BDKRB2 (bradykinin receptor B2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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624 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Bradykinin receptor B2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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BDKRB2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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B2R, BK-2, BK2, BKR2, BRB2 |
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Chromosome
Chromosome number
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14 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q32.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as tr |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P30411 | ||||||||||
| Protein name | B2 bradykinin receptor (B2R) (BK-2 receptor) | ||||||||||
| Protein function | Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. | ||||||||||
| PDB | 7F2O , 7F6H , 7F6I | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Widespread in normal smooth muscle tissue and neurons. {ECO:0000269|PubMed:7835885}. | ||||||||||
| Sequence |
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| Sequence length | 391 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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