Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	6235
Gene name Gene Name - the full gene name approved by the HGNC.	Ribosomal protein S29
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RPS29
Synonyms (NCBI Gene) Gene synonyms aliases	DBA13, S29, uS14
Disease Acronyms (UniProt) Disease acronyms from UniProt database	DBA13
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q21.3
Summary Summary of gene provided in NCBI Entrez Gene.	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal pro

Show/Hide all(82)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016617	hsa-miR-484	Sequencing	20371350
MIRT027890	hsa-miR-96-5p	Sequencing	20371350
MIRT047627	hsa-miR-10a-5p	CLASH	23622248
MIRT039486	hsa-miR-652-3p	CLASH	23622248
MIRT1317956	hsa-miR-135a	CLIP-seq
MIRT1317957	hsa-miR-135b	CLIP-seq
MIRT1317958	hsa-miR-3119	CLIP-seq
MIRT1317959	hsa-miR-3124-3p	CLIP-seq
MIRT1317960	hsa-miR-4426	CLIP-seq
MIRT1317961	hsa-miR-4647	CLIP-seq
MIRT1317962	hsa-miR-4662b	CLIP-seq
MIRT1317963	hsa-miR-105	CLIP-seq
MIRT1317964	hsa-miR-1252	CLIP-seq
MIRT1317965	hsa-miR-1305	CLIP-seq
MIRT1317966	hsa-miR-186	CLIP-seq
MIRT1317967	hsa-miR-2681	CLIP-seq
MIRT1317968	hsa-miR-300	CLIP-seq
MIRT1317969	hsa-miR-3179	CLIP-seq
MIRT1317970	hsa-miR-3671	CLIP-seq
MIRT1317971	hsa-miR-381	CLIP-seq
MIRT1317972	hsa-miR-4666-3p	CLIP-seq
MIRT1317973	hsa-miR-500a	CLIP-seq
MIRT1317974	hsa-miR-520d-5p	CLIP-seq
MIRT1317975	hsa-miR-524-5p	CLIP-seq
MIRT1317976	hsa-miR-607	CLIP-seq
MIRT1317963	hsa-miR-105	CLIP-seq
MIRT1317970	hsa-miR-3671	CLIP-seq
MIRT1317976	hsa-miR-607	CLIP-seq
MIRT2094468	hsa-miR-1178	CLIP-seq
MIRT2094469	hsa-miR-1226	CLIP-seq
MIRT2094470	hsa-miR-1285	CLIP-seq
MIRT2094471	hsa-miR-150	CLIP-seq
MIRT2094472	hsa-miR-1587	CLIP-seq
MIRT2094473	hsa-miR-218	CLIP-seq
MIRT1317959	hsa-miR-3124-3p	CLIP-seq
MIRT2094474	hsa-miR-3138	CLIP-seq
MIRT2094475	hsa-miR-3147	CLIP-seq
MIRT2094476	hsa-miR-3180-5p	CLIP-seq
MIRT2094477	hsa-miR-3187-5p	CLIP-seq
MIRT2094478	hsa-miR-3619-3p	CLIP-seq
MIRT2094479	hsa-miR-3945	CLIP-seq
MIRT2094480	hsa-miR-409-3p	CLIP-seq
MIRT2094481	hsa-miR-4252	CLIP-seq
MIRT2094482	hsa-miR-4253	CLIP-seq
MIRT2094483	hsa-miR-4425	CLIP-seq
MIRT2094484	hsa-miR-455-5p	CLIP-seq
MIRT2094485	hsa-miR-4713-5p	CLIP-seq
MIRT2094486	hsa-miR-4733-3p	CLIP-seq
MIRT2094487	hsa-miR-4752	CLIP-seq
MIRT2094488	hsa-miR-4776-5p	CLIP-seq
MIRT2094489	hsa-miR-4781-3p	CLIP-seq
MIRT2094490	hsa-miR-4786-3p	CLIP-seq
MIRT2094491	hsa-miR-4800-5p	CLIP-seq
MIRT2094492	hsa-miR-511	CLIP-seq
MIRT2094493	hsa-miR-520a-5p	CLIP-seq
MIRT2094494	hsa-miR-525-5p	CLIP-seq
MIRT2094495	hsa-miR-532-3p	CLIP-seq
MIRT2094496	hsa-miR-612	CLIP-seq
MIRT2094497	hsa-miR-634	CLIP-seq
MIRT2094498	hsa-miR-636	CLIP-seq
MIRT2094499	hsa-miR-873	CLIP-seq
MIRT2094468	hsa-miR-1178	CLIP-seq
MIRT2094469	hsa-miR-1226	CLIP-seq
MIRT2318981	hsa-miR-1266	CLIP-seq
MIRT2094471	hsa-miR-150	CLIP-seq
MIRT2094472	hsa-miR-1587	CLIP-seq
MIRT2318982	hsa-miR-2392	CLIP-seq
MIRT2094475	hsa-miR-3147	CLIP-seq
MIRT2318983	hsa-miR-3187-3p	CLIP-seq
MIRT2318984	hsa-miR-3664-3p	CLIP-seq
MIRT2318985	hsa-miR-3682-3p	CLIP-seq
MIRT2094480	hsa-miR-409-3p	CLIP-seq
MIRT2094483	hsa-miR-4425	CLIP-seq
MIRT2318986	hsa-miR-4518	CLIP-seq
MIRT2318987	hsa-miR-4529-5p	CLIP-seq
MIRT2318988	hsa-miR-4674	CLIP-seq
MIRT2094485	hsa-miR-4713-5p	CLIP-seq
MIRT2094486	hsa-miR-4733-3p	CLIP-seq
MIRT2094489	hsa-miR-4781-3p	CLIP-seq
MIRT2094495	hsa-miR-532-3p	CLIP-seq
MIRT2094497	hsa-miR-634	CLIP-seq
MIRT2318989	hsa-miR-635	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000184	Process	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	TAS
GO:0002181	Process	Cytoplasmic translation	IDA	25957688
GO:0003735	Function	Structural constituent of ribosome	HDA	15883184
GO:0003735	Function	Structural constituent of ribosome	IBA	21873635
GO:0005654	Component	Nucleoplasm	TAS
GO:0005829	Component	Cytosol	TAS
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0006412	Process	Translation	IC	8706699, 15883184
GO:0006413	Process	Translational initiation	TAS
GO:0006614	Process	SRP-dependent cotranslational protein targeting to membrane	TAS
GO:0008270	Function	Zinc ion binding	IBA	21873635
GO:0008270	Function	Zinc ion binding	IDA	8781548, 25957688
GO:0015935	Component	Small ribosomal subunit	HDA	15883184
GO:0019083	Process	Viral transcription	TAS
GO:0022627	Component	Cytosolic small ribosomal subunit	HDA	15883184
GO:0022627	Component	Cytosolic small ribosomal subunit	IBA	21873635
GO:0022627	Component	Cytosolic small ribosomal subunit	IDA	8706699, 23636399
GO:0042788	Component	Polysomal ribosome	IDA	25957688
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:0098556	Component	Cytoplasmic side of rough endoplasmic reticulum membrane	ISS

MIM	HGNC	e!Ensembl
603633	10419	ENSG00000213741

Protein

UniProt ID

P62273

Protein name

Small ribosomal subunit protein uS14 (40S ribosomal protein S29)

Protein function

Component of the small ribosomal subunit (PubMed:23636399, PubMed:25901680, PubMed:25957688). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:25901680, PubMed:25957

PDB

4UG0 , 4V6X , 5A2Q , 5AJ0 , 5FLX , 5LKS , 5OA3 , 5T2C , 5VYC , 6FEC , 6G51 , 6G53 , 6G5H , 6G5I , 6IP5 , 6IP6 , 6IP8 , 6OLE , 6OLF , 6OLG , 6OLI , 6OLZ , 6OM0 , 6OM7 , 6QZP , 6XA1 , 6Y0G , 6Y2L , 6Y57 , 6YBS , 6Z6L , 6Z6M , 6Z6N , 6ZLW , 6ZM7 , 6ZME , 6ZMI , 6ZMO , 6ZMT , 6ZMW , 6ZN5 , 6ZOJ , 6ZOL , 6ZON , 6ZP4 , 6ZUO , 6ZV6 , 6ZVH , 6ZVJ , 6ZXD , 6ZXE

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00253	Ribosomal_S14	6 → 55	Ribosomal protein S14p/S29e	Family

Sequence

MGHQQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKLD

Sequence length

Interactions

View interactions

	KEGG		Reactome
	Ribosome Coronavirus disease - COVID-19		L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Show/Hide Causal Diseases (4)

Disease term	Disease name	dbSNP ID	References
Causal
Anemia	Anemia, Macrocytic, Normocytic anemia, Anemia, Diamond-Blackfan	rs118204044, rs118204045, rs118204046, rs121918330, rs869320719, rs869312029, rs121918332, rs869320724, rs767094129, rs786205058, rs786205059, rs137853119, rs137853120, rs137853121, rs1384933966 View all (89 more)	24829207, 28297620
Diamond-blackfan anemia	DIAMOND-BLACKFAN ANEMIA 13	rs121434389, rs1570566590, rs151155897, rs143951267, rs267607023, rs786200892, rs148622862, rs397507554, rs121434405, rs1571026775, rs142156224, rs267607021, rs1581931541, rs267607022, rs61762293 View all (76 more)	24829207
Leukemia	Acute leukemia	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297
Migraine	Migraine Disorders	rs794727411

Show/Hide Text Mining Associations (7)

Disease Name	Relationship Type	References
Associations from Text Mining
Alzheimer Disease	Associate	34326892
Anemia Diamond Blackfan	Associate	20116044
Brain Damage Chronic	Associate	37063869
COVID 19	Associate	37063869
Neoplasms	Associate	10708601, 19650912
Pre Eclampsia	Associate	30653101
Squamous Cell Carcinoma of Head and Neck	Associate	19650912

RPS29 (ribosomal protein S29)