Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	6208
Gene name Gene Name - the full gene name approved by the HGNC.	Ribosomal protein S14
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RPS14
Synonyms (NCBI Gene) Gene synonyms aliases	EMTB, S14, uS11
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5q33.1
Summary Summary of gene provided in NCBI Entrez Gene.	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal pro

Show/Hide all(106)

miRTarBase ID	miRNA	Experiments	Reference
MIRT050273	hsa-miR-25-3p	CLASH	23622248
MIRT049275	hsa-miR-92a-3p	CLASH	23622248
MIRT044278	hsa-miR-106b-5p	CLASH	23622248
MIRT043360	hsa-miR-331-3p	CLASH	23622248
MIRT043360	hsa-miR-331-3p	CLASH	23622248
MIRT041923	hsa-miR-484	CLASH	23622248
MIRT041170	hsa-miR-181d-5p	CLASH	23622248
MIRT040719	hsa-miR-92b-3p	CLASH	23622248
MIRT037567	hsa-miR-744-5p	CLASH	23622248
MIRT468959	hsa-miR-8060	PAR-CLIP	20371350
MIRT468957	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT468956	hsa-miR-4493	PAR-CLIP	20371350
MIRT468950	hsa-miR-4666a-5p	PAR-CLIP	20371350
MIRT468949	hsa-miR-4477a	PAR-CLIP	20371350
MIRT468948	hsa-miR-6126	PAR-CLIP	20371350
MIRT468959	hsa-miR-8060	PAR-CLIP	20371350
MIRT468957	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT468956	hsa-miR-4493	PAR-CLIP	20371350
MIRT468950	hsa-miR-4666a-5p	PAR-CLIP	20371350
MIRT468949	hsa-miR-4477a	PAR-CLIP	20371350
MIRT468948	hsa-miR-6126	PAR-CLIP	20371350
MIRT563169	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT563168	hsa-miR-4464	PAR-CLIP	20371350
MIRT563167	hsa-miR-4748	PAR-CLIP	20371350
MIRT563166	hsa-miR-455-5p	PAR-CLIP	20371350
MIRT563165	hsa-miR-3665	PAR-CLIP	20371350
MIRT563164	hsa-miR-657	PAR-CLIP	20371350
MIRT563163	hsa-miR-5087	PAR-CLIP	20371350
MIRT563162	hsa-miR-1227-3p	PAR-CLIP	20371350
MIRT563161	hsa-miR-8068	PAR-CLIP	20371350
MIRT563160	hsa-miR-3924	PAR-CLIP	20371350
MIRT563159	hsa-miR-4659a-5p	PAR-CLIP	20371350
MIRT563158	hsa-miR-4659b-5p	PAR-CLIP	20371350
MIRT468959	hsa-miR-8060	PAR-CLIP	23446348
MIRT468958	hsa-miR-494-3p	PAR-CLIP	23446348
MIRT468957	hsa-miR-605-3p	PAR-CLIP	23446348
MIRT468956	hsa-miR-4493	PAR-CLIP	23446348
MIRT468950	hsa-miR-4666a-5p	PAR-CLIP	23446348
MIRT468949	hsa-miR-4477a	PAR-CLIP	23446348
MIRT468948	hsa-miR-6126	PAR-CLIP	23446348
MIRT468947	hsa-miR-510-3p	PAR-CLIP	23446348
MIRT468959	hsa-miR-8060	PAR-CLIP	23592263
MIRT468958	hsa-miR-494-3p	PAR-CLIP	23592263
MIRT468957	hsa-miR-605-3p	PAR-CLIP	23592263
MIRT468956	hsa-miR-4493	PAR-CLIP	23592263
MIRT468955	hsa-miR-219a-1-3p	PAR-CLIP	23592263
MIRT468954	hsa-miR-3135b	PAR-CLIP	23592263
MIRT468953	hsa-miR-4653-3p	PAR-CLIP	23592263
MIRT468952	hsa-miR-3652	PAR-CLIP	23592263
MIRT468951	hsa-miR-4430	PAR-CLIP	23592263
MIRT468950	hsa-miR-4666a-5p	PAR-CLIP	23592263
MIRT468949	hsa-miR-4477a	PAR-CLIP	23592263
MIRT468948	hsa-miR-6126	PAR-CLIP	23592263
MIRT468947	hsa-miR-510-3p	PAR-CLIP	23592263
MIRT468959	hsa-miR-8060	PAR-CLIP	20371350
MIRT468957	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT468956	hsa-miR-4493	PAR-CLIP	20371350
MIRT468950	hsa-miR-4666a-5p	PAR-CLIP	20371350
MIRT468949	hsa-miR-4477a	PAR-CLIP	20371350
MIRT468948	hsa-miR-6126	PAR-CLIP	20371350
MIRT468959	hsa-miR-8060	PAR-CLIP	20371350
MIRT468957	hsa-miR-605-3p	PAR-CLIP	20371350
MIRT468956	hsa-miR-4493	PAR-CLIP	20371350
MIRT468950	hsa-miR-4666a-5p	PAR-CLIP	20371350
MIRT468949	hsa-miR-4477a	PAR-CLIP	20371350
MIRT468948	hsa-miR-6126	PAR-CLIP	20371350
MIRT563169	hsa-miR-5580-3p	PAR-CLIP	20371350
MIRT563168	hsa-miR-4464	PAR-CLIP	20371350
MIRT563167	hsa-miR-4748	PAR-CLIP	20371350
MIRT563166	hsa-miR-455-5p	PAR-CLIP	20371350
MIRT563165	hsa-miR-3665	PAR-CLIP	20371350
MIRT563164	hsa-miR-657	PAR-CLIP	20371350
MIRT563163	hsa-miR-5087	PAR-CLIP	20371350
MIRT563162	hsa-miR-1227-3p	PAR-CLIP	20371350
MIRT563161	hsa-miR-8068	PAR-CLIP	20371350
MIRT563160	hsa-miR-3924	PAR-CLIP	20371350
MIRT563159	hsa-miR-4659a-5p	PAR-CLIP	20371350
MIRT563158	hsa-miR-4659b-5p	PAR-CLIP	20371350
MIRT468959	hsa-miR-8060	PAR-CLIP	23446348
MIRT468958	hsa-miR-494-3p	PAR-CLIP	23446348
MIRT468957	hsa-miR-605-3p	PAR-CLIP	23446348
MIRT468956	hsa-miR-4493	PAR-CLIP	23446348
MIRT468950	hsa-miR-4666a-5p	PAR-CLIP	23446348
MIRT468949	hsa-miR-4477a	PAR-CLIP	23446348
MIRT468948	hsa-miR-6126	PAR-CLIP	23446348
MIRT468947	hsa-miR-510-3p	PAR-CLIP	23446348
MIRT468959	hsa-miR-8060	PAR-CLIP	23592263
MIRT468958	hsa-miR-494-3p	PAR-CLIP	23592263
MIRT468957	hsa-miR-605-3p	PAR-CLIP	23592263
MIRT468956	hsa-miR-4493	PAR-CLIP	23592263
MIRT468955	hsa-miR-219a-1-3p	PAR-CLIP	23592263
MIRT468954	hsa-miR-3135b	PAR-CLIP	23592263
MIRT468953	hsa-miR-4653-3p	PAR-CLIP	23592263
MIRT468952	hsa-miR-3652	PAR-CLIP	23592263
MIRT468951	hsa-miR-4430	PAR-CLIP	23592263
MIRT468950	hsa-miR-4666a-5p	PAR-CLIP	23592263
MIRT468949	hsa-miR-4477a	PAR-CLIP	23592263
MIRT468948	hsa-miR-6126	PAR-CLIP	23592263
MIRT468947	hsa-miR-510-3p	PAR-CLIP	23592263
MIRT1317710	hsa-miR-4666-5p	CLIP-seq
MIRT1317711	hsa-miR-494	CLIP-seq
MIRT2094424	hsa-miR-1224-5p	CLIP-seq
MIRT2094425	hsa-miR-1304	CLIP-seq
MIRT2094426	hsa-miR-3915	CLIP-seq
MIRT2094427	hsa-miR-3928	CLIP-seq
MIRT2094428	hsa-miR-4689	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000028	Process	Ribosomal small subunit assembly	IBA
GO:0000028	Process	Ribosomal small subunit assembly	ISS
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	7867928
GO:0002181	Process	Cytoplasmic translation	IC	3785212, 8706699, 15883184, 23636399
GO:0002181	Process	Cytoplasmic translation	IMP	3683397, 9152021
GO:0002181	Process	Cytoplasmic translation	NAS	25901680
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	ISS
GO:0003735	Function	Structural constituent of ribosome	HDA	15883184
GO:0003735	Function	Structural constituent of ribosome	IBA
GO:0003735	Function	Structural constituent of ribosome	IDA	23636399
GO:0003735	Function	Structural constituent of ribosome	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 16713569, 24965446, 25009770, 25416956, 28514442, 30021884, 32296183, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IDA	9152021
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	NAS	25901680
GO:0005829	Component	Cytosol	TAS
GO:0005840	Component	Ribosome	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0006412	Process	Translation	IBA
GO:0006412	Process	Translation	IEA
GO:0014069	Component	Postsynaptic density	EXP	21170055
GO:0014069	Component	Postsynaptic density	IDA	21170055
GO:0016020	Component	Membrane	HDA	19946888
GO:0022626	Component	Cytosolic ribosome	IDA	23636399
GO:0022627	Component	Cytosolic small ribosomal subunit	HDA	15883184
GO:0022627	Component	Cytosolic small ribosomal subunit	IBA
GO:0022627	Component	Cytosolic small ribosomal subunit	IDA	8706699, 9152021
GO:0022627	Component	Cytosolic small ribosomal subunit	IEA
GO:0022627	Component	Cytosolic small ribosomal subunit	NAS	25901680
GO:0030218	Process	Erythrocyte differentiation	IMP	18202658
GO:0030490	Process	Maturation of SSU-rRNA	ISS
GO:0032040	Component	Small-subunit processome	IDA	34516797
GO:0042274	Process	Ribosomal small subunit biogenesis	IDA	34516797
GO:0045202	Component	Synapse	IEA
GO:0048027	Function	MRNA 5'-UTR binding	IDA	7867928
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
130620	10387	ENSG00000164587

Protein

UniProt ID

P62263

Protein name

Small ribosomal subunit protein uS11 (40S ribosomal protein S14)

Protein function

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subu

PDB

4UG0 , 4V6X , 5A2Q , 5AJ0 , 5FLX , 5LKS , 5OA3 , 5T2C , 5VYC , 6FEC , 6G18 , 6G4S , 6G4W , 6G51 , 6G53 , 6G5H , 6G5I , 6IP5 , 6IP6 , 6IP8 , 6OLE , 6OLF , 6OLG , 6OLI , 6OLZ , 6OM0 , 6OM7 , 6QZP , 6XA1 , 6Y0G , 6Y2L , 6Y57 , 6YBD , 6YBW , 6Z6L , 6Z6M , 6Z6N , 6ZLW , 6ZM7 , 6ZME , 6ZMI , 6ZMO , 6ZMT , 6ZMW , 6ZN5 , 6ZOJ , 6ZOK , 6ZON , 6ZP4 , 6ZUO , 6ZV6

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00411	Ribosomal_S11	29 → 147	Ribosomal protein S11	Family

Sequence

MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGM
KVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALA
RSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Sequence length

151

Interactions

View interactions

	KEGG		Reactome
	Ribosome Coronavirus disease - COVID-19		L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

RPS14 (ribosomal protein S14)