Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	6152
Gene name Gene Name - the full gene name approved by the HGNC.	Ribosomal protein L24
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RPL24
Synonyms (NCBI Gene) Gene synonyms aliases	HEL-S-310, L24, eL24
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q12.3
Summary Summary of gene provided in NCBI Entrez Gene.	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal pro

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miRTarBase ID	miRNA	Experiments	Reference
MIRT050454	hsa-miR-22-3p	CLASH	23622248
MIRT048982	hsa-miR-92a-3p	CLASH	23622248
MIRT040955	hsa-miR-18a-3p	CLASH	23622248
MIRT716128	hsa-miR-1277-5p	HITS-CLIP	19536157
MIRT716127	hsa-miR-302a-5p	HITS-CLIP	19536157
MIRT716126	hsa-miR-374a-3p	HITS-CLIP	19536157
MIRT716125	hsa-miR-6813-3p	HITS-CLIP	19536157
MIRT716124	hsa-miR-6508-5p	HITS-CLIP	19536157
MIRT716123	hsa-miR-8067	HITS-CLIP	19536157
MIRT716122	hsa-miR-4668-5p	HITS-CLIP	19536157
MIRT690351	hsa-miR-4798-3p	HITS-CLIP	23313552
MIRT690350	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT690349	hsa-miR-6499-5p	HITS-CLIP	23313552
MIRT690348	hsa-miR-4743-5p	HITS-CLIP	23313552
MIRT690347	hsa-miR-3178	HITS-CLIP	23313552
MIRT690346	hsa-miR-7977	HITS-CLIP	23313552
MIRT690345	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT690344	hsa-miR-3122	HITS-CLIP	23313552
MIRT690343	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT690342	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT690341	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT679718	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT679717	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT679716	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT679715	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT679714	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT679713	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679712	hsa-miR-1976	HITS-CLIP	23824327
MIRT679711	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679710	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679709	hsa-miR-4454	HITS-CLIP	23824327
MIRT679708	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679707	hsa-miR-433-3p	HITS-CLIP	23824327
MIRT679706	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT559986	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT559985	hsa-miR-4769-3p	PAR-CLIP	20371350
MIRT559984	hsa-miR-6817-5p	PAR-CLIP	20371350
MIRT559983	hsa-miR-374a-5p	PAR-CLIP	20371350
MIRT559982	hsa-miR-374b-5p	PAR-CLIP	20371350
MIRT559981	hsa-miR-4727-5p	PAR-CLIP	20371350
MIRT048982	hsa-miR-92a-3p	PAR-CLIP	27292025
MIRT716128	hsa-miR-1277-5p	HITS-CLIP	19536157
MIRT716127	hsa-miR-302a-5p	HITS-CLIP	19536157
MIRT716126	hsa-miR-374a-3p	HITS-CLIP	19536157
MIRT716125	hsa-miR-6813-3p	HITS-CLIP	19536157
MIRT716124	hsa-miR-6508-5p	HITS-CLIP	19536157
MIRT716123	hsa-miR-8067	HITS-CLIP	19536157
MIRT716122	hsa-miR-4668-5p	HITS-CLIP	19536157
MIRT690351	hsa-miR-4798-3p	HITS-CLIP	23313552
MIRT690350	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT690349	hsa-miR-6499-5p	HITS-CLIP	23313552
MIRT690348	hsa-miR-4743-5p	HITS-CLIP	23313552
MIRT690347	hsa-miR-3178	HITS-CLIP	23313552
MIRT690346	hsa-miR-7977	HITS-CLIP	23313552
MIRT690345	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT690344	hsa-miR-3122	HITS-CLIP	23313552
MIRT690343	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT690342	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT690341	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT679718	hsa-miR-186-3p	HITS-CLIP	23824327
MIRT679717	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT679716	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT679715	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT679714	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT679713	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679712	hsa-miR-1976	HITS-CLIP	23824327
MIRT679711	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679710	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679709	hsa-miR-4454	HITS-CLIP	23824327
MIRT679708	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679707	hsa-miR-433-3p	HITS-CLIP	23824327
MIRT679706	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT559986	hsa-miR-548c-3p	PAR-CLIP	20371350
MIRT559985	hsa-miR-4769-3p	PAR-CLIP	20371350
MIRT559984	hsa-miR-6817-5p	PAR-CLIP	20371350
MIRT559983	hsa-miR-374a-5p	PAR-CLIP	20371350
MIRT559982	hsa-miR-374b-5p	PAR-CLIP	20371350
MIRT559981	hsa-miR-4727-5p	PAR-CLIP	20371350

Show/Hide all(30)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000027	Process	Ribosomal large subunit assembly	IBA	21873635
GO:0000184	Process	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	TAS
GO:0002181	Process	Cytoplasmic translation	IDA	25957688
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IBA	21873635
GO:0003735	Function	Structural constituent of ribosome	IBA	21873635
GO:0003735	Function	Structural constituent of ribosome	NAS	12962325
GO:0005515	Function	Protein binding	IPI	24965446
GO:0005737	Component	Cytoplasm	IDA	25468996
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006412	Process	Translation	IBA	21873635
GO:0006412	Process	Translation	NAS	12962325
GO:0006413	Process	Translational initiation	TAS
GO:0006614	Process	SRP-dependent cotranslational protein targeting to membrane	TAS
GO:0010458	Process	Exit from mitosis	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0019083	Process	Viral transcription	TAS
GO:0021554	Process	Optic nerve development	IEA
GO:0022625	Component	Cytosolic large ribosomal subunit	HDA	12962325
GO:0022625	Component	Cytosolic large ribosomal subunit	IBA	21873635
GO:0022625	Component	Cytosolic large ribosomal subunit	IDA	25957688
GO:0031290	Process	Retinal ganglion cell axon guidance	IEA
GO:0042788	Component	Polysomal ribosome	IDA	25957688
GO:0045202	Component	Synapse	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0060041	Process	Retina development in camera-type eye	IEA
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:1902626	Process	Assembly of large subunit precursor of preribosome	IBA	21873635

MIM	HGNC	e!Ensembl
604180	10325	ENSG00000114391

Protein

UniProt ID

P83731

Protein name

Large ribosomal subunit protein eL24 (60S ribosomal protein L24) (60S ribosomal protein L30)

Protein function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

PDB

4UG0 , 4V6X , 5A2Q , 5AJ0 , 5LKS , 5T2C , 6IP5 , 6IP6 , 6IP8 , 6LQM , 6LSR , 6OLE , 6OLF , 6OLG , 6OLI , 6OLZ , 6OM0 , 6OM7 , 6QZP , 6W6L , 6XA1 , 6Y0G , 6Y2L , 6Y57 , 6Y6X , 6Z6L , 6Z6M , 6Z6N , 6ZM7 , 6ZME , 6ZMI , 6ZMO , 7BHP , 7F5S , 7OW7 , 7XNX , 7XNY , 8A3D , 8G5Y , 8G60 , 8G61 , 8G6J , 8GLP , 8IFD , 8IFE , 8JDJ , 8JDK , 8JDL , 8JDM , 8K2C , 8OHD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01246	Ribosomal_L24e	1 → 66	Ribosomal protein L24e	Domain

Sequence

MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHK
KGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQ
ASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR

Sequence length

157

Interactions

View interactions

	KEGG		Reactome
	Ribosome Coronavirus disease - COVID-19		L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Gastrointestinal stromal tumor	Gastrointestinal Stromal Tumors, Gastrointestinal Stromal Sarcoma	rs587776653, rs74315368, rs74315369, rs587776793, rs587776794, rs587776795, rs606231209, rs121908589, rs121913685, rs121913680, rs794726675, rs587776804, rs121913517, rs121913234, rs121913512 View all (59 more)	27793025

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References
Associations from Text Mining
Alzheimer Disease	Associate	38176923
Breast Neoplasms	Associate	24970821
Carcinogenesis	Associate	24970821
Carcinoma Hepatocellular	Associate	25520117, 36378050
Diffuse Neurofibrillary Tangles with Calcification	Associate	38554950
Neoplasms	Associate	24970821, 25520117

RPL24 (ribosomal protein L24)