Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	6147
Gene name	Ribosomal protein L23a
Gene symbol	RPL23A
Synonyms (NCBI Gene)	L23AMDA20uL23
Chromosome	17
Chromosome location	17q11.2
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal pro

274

Show/Hide all (274)

miRTarBase ID	miRNA	Experiments	Reference
MIRT041229	hsa-miR-193b-3p	CLASH	23622248
MIRT039258	hsa-miR-671-5p	CLASH	23622248
MIRT039135	hsa-miR-769-3p	CLASH	23622248
MIRT038169	hsa-miR-423-5p	CLASH	23622248
MIRT037257	hsa-miR-877-5p	CLASH	23622248
MIRT286306	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT344565	hsa-miR-8076	HITS-CLIP	21572407
MIRT344563	hsa-miR-6074	HITS-CLIP	21572407
MIRT344564	hsa-miR-892c-5p	HITS-CLIP	21572407
MIRT508638	hsa-miR-506-5p	HITS-CLIP	21572407
MIRT286304	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT508637	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT286306	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT344563	hsa-miR-6074	HITS-CLIP	21572407
MIRT344564	hsa-miR-892c-5p	HITS-CLIP	21572407
MIRT508638	hsa-miR-506-5p	HITS-CLIP	21572407
MIRT286304	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT508637	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT286306	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT344565	hsa-miR-8076	PAR-CLIP	20371350
MIRT344563	hsa-miR-6074	PAR-CLIP	20371350
MIRT344564	hsa-miR-892c-5p	PAR-CLIP	20371350
MIRT508638	hsa-miR-506-5p	PAR-CLIP	20371350
MIRT286304	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT508637	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT286306	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT344565	hsa-miR-8076	PAR-CLIP	21572407
MIRT344563	hsa-miR-6074	PAR-CLIP	21572407
MIRT344564	hsa-miR-892c-5p	PAR-CLIP	21572407
MIRT508638	hsa-miR-506-5p	PAR-CLIP	21572407
MIRT286304	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT508637	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT286306	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT344565	hsa-miR-8076	PAR-CLIP	23446348
MIRT344563	hsa-miR-6074	PAR-CLIP	23446348
MIRT344564	hsa-miR-892c-5p	PAR-CLIP	23446348
MIRT508638	hsa-miR-506-5p	PAR-CLIP	23446348
MIRT286304	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT508637	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT286306	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT344565	hsa-miR-8076	PAR-CLIP	23446348
MIRT344563	hsa-miR-6074	PAR-CLIP	23446348
MIRT344564	hsa-miR-892c-5p	PAR-CLIP	23446348
MIRT508638	hsa-miR-506-5p	PAR-CLIP	23446348
MIRT286304	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT508637	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT286306	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT344565	hsa-miR-8076	HITS-CLIP	21572407
MIRT344563	hsa-miR-6074	HITS-CLIP	21572407
MIRT344564	hsa-miR-892c-5p	HITS-CLIP	21572407
MIRT508638	hsa-miR-506-5p	HITS-CLIP	21572407
MIRT286304	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT508637	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT286306	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT344563	hsa-miR-6074	HITS-CLIP	21572407
MIRT344564	hsa-miR-892c-5p	HITS-CLIP	21572407
MIRT508638	hsa-miR-506-5p	HITS-CLIP	21572407
MIRT286304	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT508637	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT286306	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT344565	hsa-miR-8076	PAR-CLIP	20371350
MIRT344563	hsa-miR-6074	PAR-CLIP	20371350
MIRT344564	hsa-miR-892c-5p	PAR-CLIP	20371350
MIRT508638	hsa-miR-506-5p	PAR-CLIP	20371350
MIRT286304	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT508637	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT286306	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT344565	hsa-miR-8076	PAR-CLIP	21572407
MIRT344563	hsa-miR-6074	PAR-CLIP	21572407
MIRT344564	hsa-miR-892c-5p	PAR-CLIP	21572407
MIRT508638	hsa-miR-506-5p	PAR-CLIP	21572407
MIRT286304	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT508637	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT286306	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT344565	hsa-miR-8076	PAR-CLIP	23446348
MIRT344563	hsa-miR-6074	PAR-CLIP	23446348
MIRT344564	hsa-miR-892c-5p	PAR-CLIP	23446348
MIRT508638	hsa-miR-506-5p	PAR-CLIP	23446348
MIRT286304	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT508637	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT286306	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT344565	hsa-miR-8076	PAR-CLIP	23446348
MIRT344563	hsa-miR-6074	PAR-CLIP	23446348
MIRT344564	hsa-miR-892c-5p	PAR-CLIP	23446348
MIRT508638	hsa-miR-506-5p	PAR-CLIP	23446348
MIRT286304	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT508637	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT1316350	hsa-let-7a	CLIP-seq
MIRT1316351	hsa-let-7b	CLIP-seq
MIRT1316352	hsa-let-7c	CLIP-seq
MIRT1316353	hsa-let-7d	CLIP-seq
MIRT1316354	hsa-let-7e	CLIP-seq
MIRT1316355	hsa-let-7f	CLIP-seq
MIRT1316356	hsa-let-7g	CLIP-seq
MIRT1316357	hsa-let-7i	CLIP-seq
MIRT1316358	hsa-miR-1	CLIP-seq
MIRT1316359	hsa-miR-1207-3p	CLIP-seq
MIRT1316360	hsa-miR-1207-5p	CLIP-seq
MIRT1316361	hsa-miR-122	CLIP-seq
MIRT1316362	hsa-miR-1294	CLIP-seq
MIRT1316363	hsa-miR-1299	CLIP-seq
MIRT1316364	hsa-miR-147	CLIP-seq
MIRT1316365	hsa-miR-202	CLIP-seq
MIRT1316366	hsa-miR-206	CLIP-seq
MIRT1316367	hsa-miR-2682	CLIP-seq
MIRT1316368	hsa-miR-3156-5p	CLIP-seq
MIRT1316369	hsa-miR-3165	CLIP-seq
MIRT1316370	hsa-miR-326	CLIP-seq
MIRT1316371	hsa-miR-330-5p	CLIP-seq
MIRT1316372	hsa-miR-3673	CLIP-seq
MIRT1316373	hsa-miR-378	CLIP-seq
MIRT1316374	hsa-miR-378b	CLIP-seq
MIRT1316375	hsa-miR-378c	CLIP-seq
MIRT1316376	hsa-miR-378d	CLIP-seq
MIRT1316377	hsa-miR-378e	CLIP-seq
MIRT1316378	hsa-miR-378f	CLIP-seq
MIRT1316379	hsa-miR-378h	CLIP-seq
MIRT1316380	hsa-miR-378i	CLIP-seq
MIRT1316381	hsa-miR-3911	CLIP-seq
MIRT1316382	hsa-miR-422a	CLIP-seq
MIRT1316383	hsa-miR-4423-3p	CLIP-seq
MIRT1316384	hsa-miR-4458	CLIP-seq
MIRT1316385	hsa-miR-449c	CLIP-seq
MIRT1316386	hsa-miR-4500	CLIP-seq
MIRT1316387	hsa-miR-4678	CLIP-seq
MIRT1316388	hsa-miR-4690-3p	CLIP-seq
MIRT1316389	hsa-miR-4710	CLIP-seq
MIRT1316390	hsa-miR-4719	CLIP-seq
MIRT1316391	hsa-miR-4736	CLIP-seq
MIRT1316392	hsa-miR-4757-5p	CLIP-seq
MIRT1316393	hsa-miR-4763-3p	CLIP-seq
MIRT1316394	hsa-miR-4802-3p	CLIP-seq
MIRT1316395	hsa-miR-485-3p	CLIP-seq
MIRT1316396	hsa-miR-487a	CLIP-seq
MIRT1316397	hsa-miR-554	CLIP-seq
MIRT1316398	hsa-miR-562	CLIP-seq
MIRT1316399	hsa-miR-607	CLIP-seq
MIRT1316400	hsa-miR-613	CLIP-seq
MIRT1316401	hsa-miR-618	CLIP-seq
MIRT1316402	hsa-miR-644	CLIP-seq
MIRT1316403	hsa-miR-663b	CLIP-seq
MIRT1316404	hsa-miR-875-3p	CLIP-seq
MIRT1316405	hsa-miR-940	CLIP-seq
MIRT1316406	hsa-miR-98	CLIP-seq
MIRT1316389	hsa-miR-4710	CLIP-seq
MIRT1316350	hsa-let-7a	CLIP-seq
MIRT1316351	hsa-let-7b	CLIP-seq
MIRT1316352	hsa-let-7c	CLIP-seq
MIRT1316353	hsa-let-7d	CLIP-seq
MIRT1316354	hsa-let-7e	CLIP-seq
MIRT1316355	hsa-let-7f	CLIP-seq
MIRT1316356	hsa-let-7g	CLIP-seq
MIRT1316357	hsa-let-7i	CLIP-seq
MIRT1316358	hsa-miR-1	CLIP-seq
MIRT1316360	hsa-miR-1207-5p	CLIP-seq
MIRT1316361	hsa-miR-122	CLIP-seq
MIRT2094027	hsa-miR-1256	CLIP-seq
MIRT2094028	hsa-miR-1285	CLIP-seq
MIRT1316363	hsa-miR-1299	CLIP-seq
MIRT2094029	hsa-miR-1324	CLIP-seq
MIRT1316365	hsa-miR-202	CLIP-seq
MIRT1316366	hsa-miR-206	CLIP-seq
MIRT1316368	hsa-miR-3156-5p	CLIP-seq
MIRT1316369	hsa-miR-3165	CLIP-seq
MIRT2094030	hsa-miR-3187-5p	CLIP-seq
MIRT1316370	hsa-miR-326	CLIP-seq
MIRT1316371	hsa-miR-330-5p	CLIP-seq
MIRT2094031	hsa-miR-3591-3p	CLIP-seq
MIRT1316372	hsa-miR-3673	CLIP-seq
MIRT2094032	hsa-miR-3945	CLIP-seq
MIRT2094033	hsa-miR-4253	CLIP-seq
MIRT2094034	hsa-miR-4292	CLIP-seq
MIRT1316384	hsa-miR-4458	CLIP-seq
MIRT1316386	hsa-miR-4500	CLIP-seq
MIRT2094035	hsa-miR-4672	CLIP-seq
MIRT1316387	hsa-miR-4678	CLIP-seq
MIRT2094036	hsa-miR-4682	CLIP-seq
MIRT1316389	hsa-miR-4710	CLIP-seq
MIRT1316390	hsa-miR-4719	CLIP-seq
MIRT1316391	hsa-miR-4736	CLIP-seq
MIRT1316393	hsa-miR-4763-3p	CLIP-seq
MIRT1316394	hsa-miR-4802-3p	CLIP-seq
MIRT1316395	hsa-miR-485-3p	CLIP-seq
MIRT1316396	hsa-miR-487a	CLIP-seq
MIRT1316397	hsa-miR-554	CLIP-seq
MIRT1316398	hsa-miR-562	CLIP-seq
MIRT1316399	hsa-miR-607	CLIP-seq
MIRT2094037	hsa-miR-612	CLIP-seq
MIRT1316400	hsa-miR-613	CLIP-seq
MIRT1316401	hsa-miR-618	CLIP-seq
MIRT1316404	hsa-miR-875-3p	CLIP-seq
MIRT1316406	hsa-miR-98	CLIP-seq
MIRT1316358	hsa-miR-1	CLIP-seq
MIRT1316359	hsa-miR-1207-3p	CLIP-seq
MIRT1316362	hsa-miR-1294	CLIP-seq
MIRT1316363	hsa-miR-1299	CLIP-seq
MIRT2094029	hsa-miR-1324	CLIP-seq
MIRT1316366	hsa-miR-206	CLIP-seq
MIRT1316367	hsa-miR-2682	CLIP-seq
MIRT1316368	hsa-miR-3156-5p	CLIP-seq
MIRT1316370	hsa-miR-326	CLIP-seq
MIRT1316371	hsa-miR-330-5p	CLIP-seq
MIRT1316372	hsa-miR-3673	CLIP-seq
MIRT1316373	hsa-miR-378	CLIP-seq
MIRT1316374	hsa-miR-378b	CLIP-seq
MIRT1316375	hsa-miR-378c	CLIP-seq
MIRT1316376	hsa-miR-378d	CLIP-seq
MIRT1316377	hsa-miR-378e	CLIP-seq
MIRT1316378	hsa-miR-378f	CLIP-seq
MIRT1316379	hsa-miR-378h	CLIP-seq
MIRT1316380	hsa-miR-378i	CLIP-seq
MIRT2318595	hsa-miR-411	CLIP-seq
MIRT1316382	hsa-miR-422a	CLIP-seq
MIRT1316383	hsa-miR-4423-3p	CLIP-seq
MIRT1316385	hsa-miR-449c	CLIP-seq
MIRT2318596	hsa-miR-4520a-3p	CLIP-seq
MIRT2318597	hsa-miR-4520b-3p	CLIP-seq
MIRT2094036	hsa-miR-4682	CLIP-seq
MIRT1316389	hsa-miR-4710	CLIP-seq
MIRT1316390	hsa-miR-4719	CLIP-seq
MIRT1316395	hsa-miR-485-3p	CLIP-seq
MIRT1316396	hsa-miR-487a	CLIP-seq
MIRT1316397	hsa-miR-554	CLIP-seq
MIRT1316400	hsa-miR-613	CLIP-seq
MIRT1316404	hsa-miR-875-3p	CLIP-seq
MIRT1316405	hsa-miR-940	CLIP-seq
MIRT2094029	hsa-miR-1324	CLIP-seq
MIRT1316389	hsa-miR-4710	CLIP-seq
MIRT2614303	hsa-miR-1236	CLIP-seq
MIRT2094027	hsa-miR-1256	CLIP-seq
MIRT2094028	hsa-miR-1285	CLIP-seq
MIRT1316364	hsa-miR-147	CLIP-seq
MIRT2094030	hsa-miR-3187-5p	CLIP-seq
MIRT2094031	hsa-miR-3591-3p	CLIP-seq
MIRT2614304	hsa-miR-3612	CLIP-seq
MIRT1316381	hsa-miR-3911	CLIP-seq
MIRT2094032	hsa-miR-3945	CLIP-seq
MIRT2094033	hsa-miR-4253	CLIP-seq
MIRT2094034	hsa-miR-4292	CLIP-seq
MIRT2614305	hsa-miR-4303	CLIP-seq
MIRT2614306	hsa-miR-4443	CLIP-seq
MIRT2094035	hsa-miR-4672	CLIP-seq
MIRT2094036	hsa-miR-4682	CLIP-seq
MIRT2614307	hsa-miR-4685-5p	CLIP-seq
MIRT1316388	hsa-miR-4690-3p	CLIP-seq
MIRT1316392	hsa-miR-4757-5p	CLIP-seq
MIRT2614308	hsa-miR-4802-5p	CLIP-seq
MIRT1316395	hsa-miR-485-3p	CLIP-seq
MIRT2614309	hsa-miR-578	CLIP-seq
MIRT2094037	hsa-miR-612	CLIP-seq
MIRT2614310	hsa-miR-643	CLIP-seq
MIRT1316402	hsa-miR-644	CLIP-seq
MIRT2614311	hsa-miR-650	CLIP-seq
MIRT1316403	hsa-miR-663b	CLIP-seq
MIRT2614312	hsa-miR-888	CLIP-seq
MIRT2614303	hsa-miR-1236	CLIP-seq
MIRT2094027	hsa-miR-1256	CLIP-seq
MIRT2094028	hsa-miR-1285	CLIP-seq
MIRT2094030	hsa-miR-3187-5p	CLIP-seq
MIRT2094031	hsa-miR-3591-3p	CLIP-seq
MIRT2614304	hsa-miR-3612	CLIP-seq
MIRT2094032	hsa-miR-3945	CLIP-seq
MIRT2094033	hsa-miR-4253	CLIP-seq
MIRT2094034	hsa-miR-4292	CLIP-seq
MIRT2614306	hsa-miR-4443	CLIP-seq
MIRT2094035	hsa-miR-4672	CLIP-seq
MIRT2614307	hsa-miR-4685-5p	CLIP-seq
MIRT2614308	hsa-miR-4802-5p	CLIP-seq
MIRT1316395	hsa-miR-485-3p	CLIP-seq
MIRT2614309	hsa-miR-578	CLIP-seq
MIRT2094037	hsa-miR-612	CLIP-seq
MIRT2614310	hsa-miR-643	CLIP-seq
MIRT2614311	hsa-miR-650	CLIP-seq
MIRT2614312	hsa-miR-888	CLIP-seq

Show/Hide all (31)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002181	Process	Cytoplasmic translation	IC	23636399
GO:0002181	Process	Cytoplasmic translation	NAS	25901680
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0003735	Function	Structural constituent of ribosome	IBA
GO:0003735	Function	Structural constituent of ribosome	IDA	23636399, 32669547
GO:0003735	Function	Structural constituent of ribosome	IEA
GO:0003735	Function	Structural constituent of ribosome	NAS	9417910, 12962325
GO:0005515	Function	Protein binding	IPI	9687515, 23414517, 24725412, 24965446, 30021884, 33961781, 35637966
GO:0005634	Component	Nucleus	IDA	9687515
GO:0005634	Component	Nucleus	IEA
GO:0005730	Component	Nucleolus	HDA	16791210
GO:0005737	Component	Cytoplasm	HDA	16791210
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	NAS	25901680
GO:0005829	Component	Cytosol	TAS
GO:0005840	Component	Ribosome	IEA
GO:0006412	Process	Translation	IEA
GO:0006412	Process	Translation	NAS	9417910, 12962325
GO:0019843	Function	RRNA binding	IEA
GO:0022625	Component	Cytosolic large ribosomal subunit	HDA	12962325
GO:0022625	Component	Cytosolic large ribosomal subunit	IBA
GO:0022625	Component	Cytosolic large ribosomal subunit	IDA	32669547
GO:0022625	Component	Cytosolic large ribosomal subunit	IEA
GO:0022625	Component	Cytosolic large ribosomal subunit	IPI	25901680
GO:0022625	Component	Cytosolic large ribosomal subunit	NAS	9417910
GO:0022626	Component	Cytosolic ribosome	IDA	23636399
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:1904841	Function	TORC2 complex binding	ISS
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
602326	10317	ENSG00000198242

P62750

Protein name

Large ribosomal subunit protein uL23 (60S ribosomal protein L23a)

Protein function

Component of the large ribosomal subunit (PubMed:23636399, PubMed:32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:32669547). Binds a specific region on t

PDB

4UG0 , 4V6X , 5AJ0 , 5LKS , 5T2C , 6IP5 , 6IP6 , 6IP8 , 6LQM , 6LSR , 6LSS , 6LU8 , 6OLE , 6OLF , 6OLG , 6OLI , 6OLZ , 6OM0 , 6OM7 , 6QZP , 6SXO , 6W6L , 6XA1 , 6Y0G , 6Y2L , 6Y57 , 6Y6X , 6Z6L , 6Z6M , 6Z6N , 6ZM7 , 6ZME , 6ZMI , 6ZMO , 7BHP , 7F5S , 7OW7 , 7QVP , 7XNX , 7XNY , 8A3D , 8FKP , 8FKQ , 8FKR , 8FKS , 8FKT , 8FKU , 8FKV , 8FKW , 8FKX , 8FKY

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03939	Ribosomal_L23eN	17 → 67	Ribosomal protein L23, N-terminal domain	Family
PF00276	Ribosomal_L23	75 → 148	Ribosomal protein L23	Family

Sequence

MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKY
PRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDID
VAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII

Sequence length

156

Interactions

View interactions

	KEGG		Reactome
	Ribosome Coronavirus disease - COVID-19		L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

RPL23A (ribosomal protein L23a)