Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6138
Gene name Gene Name - the full gene name approved by the HGNC.
Ribosomal protein L15
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RPL15
Synonyms (NCBI Gene) Gene synonyms aliases
DBA12, EC45, L15, RPL10, RPLY10, RPYL10, eL15
Disease Acronyms (UniProt) Disease acronyms from UniProt database
DBA12
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p24.2
Summary Summary of gene provided in NCBI Entrez Gene.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT025638 hsa-miR-7-5p Microarray 19073608
MIRT025638 hsa-miR-7-5p Microarray 17612493
MIRT049215 hsa-miR-92a-3p CLASH 23622248
MIRT048511 hsa-miR-100-5p CLASH 23622248
MIRT047531 hsa-miR-10a-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000184 Process Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
GO:0002181 Process Cytoplasmic translation IBA 21873635
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IBA 21873635
GO:0003735 Function Structural constituent of ribosome IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
604174 10306 ENSG00000174748
Protein
UniProt ID P61313
Protein name Large ribosomal subunit protein eL15 (60S ribosomal protein L15)
Protein function Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
PDB 4UG0 , 4V6X , 5AJ0 , 5LKS , 5T2C , 6IP5 , 6IP6 , 6IP8 , 6LQM , 6LSR , 6LSS , 6LU8 , 6OLE , 6OLF , 6OLG , 6OLI , 6OLZ , 6OM0 , 6OM7 , 6QZP , 6W6L , 6XA1 , 6Y0G , 6Y2L , 6Y57 , 6Y6X , 6Z6L , 6Z6M , 6Z6N , 6ZM7 , 6ZME , 6ZMI , 6ZMO , 7BHP , 7F5S , 7OW7 , 7XNX , 7XNY , 8A3D , 8FKP , 8FKQ , 8FKR , 8FKS , 8FKT , 8FKU , 8FKV , 8FKW , 8FKX , 8FKY , 8FKZ , 8FL2
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00827 Ribosomal_L15e 2 191 Ribosomal L15 Family
Sequence
Sequence length 204
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Ribosome
Coronavirus disease - COVID-19
  L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Anemia Anemia, Macrocytic, Anemia, Diamond-Blackfan rs118204044, rs118204045, rs118204046, rs121918330, rs869320719, rs869312029, rs121918332, rs869320724, rs767094129, rs786205058, rs786205059, rs137853119, rs137853120, rs137853121, rs1384933966
View all (89 more)
28297620, 23812780
Diamond-blackfan anemia DIAMOND-BLACKFAN ANEMIA 12 rs121434389, rs1570566590, rs151155897, rs143951267, rs267607023, rs786200892, rs148622862, rs397507554, rs121434405, rs1571026775, rs142156224, rs267607021, rs1581931541, rs267607022, rs61762293
View all (76 more)
29599205, 23812780
Gastric cancer Hereditary Diffuse Gastric Cancer rs137854571, rs63751108, rs34612342, rs121908383, rs121909144, rs121909775, rs121909219, rs121909223, rs63750871, rs80359530, rs121964873, rs121913530, rs606231203, rs121918505, rs587776802
View all (244 more)
21364753
Leukemia Acute leukemia rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Associate 22491060
Alzheimer Disease Associate 27050411, 35766008
Anemia Diamond Blackfan Associate 23812780, 29599205
Brain Diseases Associate 27050411
Carcinogenesis Associate 31523176
Carcinoma Renal Cell Associate 24977159
Carcinoma Squamous Cell Associate 22491060
Colorectal Neoplasms Stimulate 31523176
COVID 19 Associate 38327202
Hydrops Fetalis Associate 29599205