ROBO1 (roundabout guidance receptor 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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6091 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Roundabout guidance receptor 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ROBO1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CPHD8, DUTT1, NORS, NYS8, SAX3 |
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Chromosome
Chromosome number
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3 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3p12.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||||||||||||||||||||||||||||||||
| UniProt ID | Q9Y6N7 | |||||||||||||||||||||||||||||||||||||||||||||
| Protein name | Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) | |||||||||||||||||||||||||||||||||||||||||||||
| Protein function | Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal de | |||||||||||||||||||||||||||||||||||||||||||||
| PDB | 2EO9 , 2V9Q , 2V9R , 2V9T , 3WIH , 4HLJ , 5O5G , 5O5I , 5OPE , 6A77 , 6A78 , 6A79 | |||||||||||||||||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed, with exception of kidney. {ECO:0000269|PubMed:9608531}. | |||||||||||||||||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 1651 | |||||||||||||||||||||||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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