ROBO1 (roundabout guidance receptor 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 6091 |
| Gene name | Roundabout guidance receptor 1 |
| Gene symbol | ROBO1 |
| Synonyms (NCBI Gene) |
CPHD8DUTT1NORSNYS8SAX3
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| Chromosome | 3 |
| Chromosome location | 3p12.3 |
| Summary | Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The |
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miRNA
miRNA information provided by mirtarbase database.
522
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
53
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y6N7 | |||||||||||||||||||||||||||||||||||||||||||||
| Protein name | Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) | |||||||||||||||||||||||||||||||||||||||||||||
| Protein function | Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal de | |||||||||||||||||||||||||||||||||||||||||||||
| PDB | 2EO9 , 2V9Q , 2V9R , 2V9T , 3WIH , 4HLJ , 5O5G , 5O5I , 5OPE , 6A77 , 6A78 , 6A79 | |||||||||||||||||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed, with exception of kidney. {ECO:0000269|PubMed:9608531}. | |||||||||||||||||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 1651 | |||||||||||||||||||||||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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