ATG101 (autophagy related 101)

Gene
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
60673
Gene name Gene Name - the full gene name approved by the HGNC.
Autophagy related 101
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ATG101
Synonyms (NCBI Gene) Gene synonyms aliases
C12orf44
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q13.13
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(11)
GO ID Ontology Definition Evidence Reference
GO:0000045 Process Autophagosome assembly IBA 21873635
GO:0000045 Process Autophagosome assembly IMP 19597335
GO:0000407 Component Phagophore assembly site IBA 21873635
GO:0000407 Component Phagophore assembly site IDA 19597335
GO:0005515 Function Protein binding IPI 19597335, 20562859, 23392225, 24290141, 26030876, 26299944, 32296183
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
615089 25679 ENSG00000123395
Protein
Gene Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q9BSB4
Protein name Autophagy-related protein 101
Protein function Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.
PDB 4WZG , 5C50 , 5XUY , 5XV1 , 5XV3 , 5XV4 , 5XV6 , 8DO8
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07855 ATG101 9 → 172 Autophagy-related protein 101 Family
Sequence
Sequence length 218
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG   Reactome
  Autophagy - other
Autophagy - animal
Longevity regulating pathway
Alzheimer disease
Amyotrophic lateral sclerosis
Huntington disease
Spinocerebellar ataxia
Pathways of neurodegeneration - multiple diseases 		  Macroautophagy
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 27935865
Show/Hide Text Mining Associations (5)
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 36302799
Colorectal Neoplasms Associate 34315829
Growth Disorders Associate 34502089
Neoplasms Associate 34502089
Osteolysis Essential Associate 35668402