SPCS3 (signal peptidase complex subunit 3)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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60559 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Signal peptidase complex subunit 3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SPCS3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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PRO3567, SPC22, SPC22/23, SPC23, SPC3, YLR066W |
Chromosome
Chromosome number
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4 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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4q34.2 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P61009 | ||||||||||
Protein name | Signal peptidase complex subunit 3 (Microsomal signal peptidase 22/23 kDa subunit) (SPC22/23) (SPase 22/23 kDa subunit) | ||||||||||
Protein function | Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:27499293, PubMed:34388369). | ||||||||||
PDB | 7P2P , 7P2Q | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 180 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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