Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6051
Gene name Gene Name - the full gene name approved by the HGNC.
Arginyl aminopeptidase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RNPEP
Synonyms (NCBI Gene) Gene synonyms aliases
AP-B, APB
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q32.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT045299 hsa-miR-186-5p CLASH 23622248
MIRT1314340 hsa-miR-1184 CLIP-seq
MIRT1314341 hsa-miR-1254 CLIP-seq
MIRT1314342 hsa-miR-153 CLIP-seq
MIRT1314343 hsa-miR-185 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004177 Function Aminopeptidase activity ISS 9405297
GO:0004177 Function Aminopeptidase activity NAS 12119107
GO:0004301 Function Epoxide hydrolase activity NAS 12119107
GO:0005576 Component Extracellular region HDA 27068509
GO:0005576 Component Extracellular region ISS 9405297
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
602675 10078 ENSG00000176393
Protein
UniProt ID Q9H4A4
Protein name Aminopeptidase B (AP-B) (EC 3.4.11.6) (Arginine aminopeptidase) (Arginyl aminopeptidase)
Protein function Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF17900 Peptidase_M1_N 37 230 Domain
PF01433 Peptidase_M1 261 482 Peptidase family M1 domain Domain
PF09127 Leuk-A4-hydro_C 530 645 Leukotriene A4 hydrolase, C-terminal Family
Sequence
Sequence length 650
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Chronic obstructive pulmonary disease Chronic Obstructive Airway Disease 26634245 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Adenoma Stimulate 26078706
Alternating hemiplegia of childhood Associate 23505069, 24709898
Breast Neoplasms Associate 20025767
Carcinogenesis Associate 26078706
Carcinoma Renal Cell Associate 16985214, 23019229
Carcinoma Renal Cell Inhibit 18216146
Colorectal Neoplasms Associate 26078706
Inflammatory Bowel Diseases Associate 29777136
Kidney Neoplasms Associate 18216146
Neoplasms Associate 16985214, 21037079