Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	60412
Gene name	Exocyst complex component 4
Gene symbol	EXOC4
Synonyms (NCBI Gene)	SEC8SEC8L1Sec8p
Chromosome	7
Chromosome location	7q33
Summary	The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and f

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miRTarBase ID	miRNA	Experiments	Reference
MIRT028232	hsa-miR-33a-5p	Sequencing	20371350
MIRT038770	hsa-miR-93-3p	CLASH	23622248
MIRT037134	hsa-miR-877-3p	CLASH	23622248
MIRT052819	hsa-miR-3200-3p	CLASH	23622248
MIRT972609	hsa-miR-23a	CLIP-seq
MIRT972610	hsa-miR-23b	CLIP-seq
MIRT972611	hsa-miR-23c	CLIP-seq
MIRT972612	hsa-miR-297	CLIP-seq
MIRT972613	hsa-miR-3149	CLIP-seq
MIRT972614	hsa-miR-3647-3p	CLIP-seq
MIRT972615	hsa-miR-409-3p	CLIP-seq
MIRT972616	hsa-miR-4263	CLIP-seq
MIRT972617	hsa-miR-4735-5p	CLIP-seq
MIRT972618	hsa-miR-4781-3p	CLIP-seq
MIRT972619	hsa-miR-576-5p	CLIP-seq
MIRT972620	hsa-miR-1253	CLIP-seq
MIRT972621	hsa-miR-1271	CLIP-seq
MIRT972622	hsa-miR-1324	CLIP-seq
MIRT972623	hsa-miR-182	CLIP-seq
MIRT972624	hsa-miR-30a	CLIP-seq
MIRT972625	hsa-miR-30b	CLIP-seq
MIRT972626	hsa-miR-30c	CLIP-seq
MIRT972627	hsa-miR-30d	CLIP-seq
MIRT972628	hsa-miR-30e	CLIP-seq
MIRT972629	hsa-miR-3120-3p	CLIP-seq
MIRT972630	hsa-miR-3545-3p	CLIP-seq
MIRT972631	hsa-miR-3607-3p	CLIP-seq
MIRT972632	hsa-miR-3613-5p	CLIP-seq
MIRT972633	hsa-miR-3908	CLIP-seq
MIRT972634	hsa-miR-3974	CLIP-seq
MIRT972635	hsa-miR-3976	CLIP-seq
MIRT972636	hsa-miR-4251	CLIP-seq
MIRT972637	hsa-miR-4433	CLIP-seq
MIRT972638	hsa-miR-4459	CLIP-seq
MIRT972639	hsa-miR-4729	CLIP-seq
MIRT972640	hsa-miR-4768-3p	CLIP-seq
MIRT972641	hsa-miR-4786-3p	CLIP-seq
MIRT972642	hsa-miR-553	CLIP-seq
MIRT972643	hsa-miR-646	CLIP-seq
MIRT972644	hsa-miR-96	CLIP-seq
MIRT972629	hsa-miR-3120-3p	CLIP-seq
MIRT1548455	hsa-miR-4789-5p	CLIP-seq
MIRT1548456	hsa-miR-922	CLIP-seq
MIRT972620	hsa-miR-1253	CLIP-seq
MIRT972621	hsa-miR-1271	CLIP-seq
MIRT972622	hsa-miR-1324	CLIP-seq
MIRT972623	hsa-miR-182	CLIP-seq
MIRT972629	hsa-miR-3120-3p	CLIP-seq
MIRT1988157	hsa-miR-3150b-3p	CLIP-seq
MIRT738444	hsa-miR-3664-5p	CLIP-seq
MIRT1988158	hsa-miR-382	CLIP-seq
MIRT972633	hsa-miR-3908	CLIP-seq
MIRT972635	hsa-miR-3976	CLIP-seq
MIRT972636	hsa-miR-4251	CLIP-seq
MIRT738445	hsa-miR-4639-3p	CLIP-seq
MIRT972639	hsa-miR-4729	CLIP-seq
MIRT1988159	hsa-miR-4784	CLIP-seq
MIRT972641	hsa-miR-4786-3p	CLIP-seq
MIRT738447	hsa-miR-539	CLIP-seq
MIRT972643	hsa-miR-646	CLIP-seq
MIRT738446	hsa-miR-668	CLIP-seq
MIRT972644	hsa-miR-96	CLIP-seq
MIRT2222638	hsa-miR-1207-3p	CLIP-seq
MIRT2222639	hsa-miR-1227	CLIP-seq
MIRT972621	hsa-miR-1271	CLIP-seq
MIRT972623	hsa-miR-182	CLIP-seq
MIRT2222640	hsa-miR-302a	CLIP-seq
MIRT2222641	hsa-miR-302b	CLIP-seq
MIRT2222642	hsa-miR-302c	CLIP-seq
MIRT2222643	hsa-miR-302d	CLIP-seq
MIRT2222644	hsa-miR-302e	CLIP-seq
MIRT972624	hsa-miR-30a	CLIP-seq
MIRT972625	hsa-miR-30b	CLIP-seq
MIRT972626	hsa-miR-30c	CLIP-seq
MIRT972627	hsa-miR-30d	CLIP-seq
MIRT972628	hsa-miR-30e	CLIP-seq
MIRT2222645	hsa-miR-3125	CLIP-seq
MIRT2222646	hsa-miR-3148	CLIP-seq
MIRT972630	hsa-miR-3545-3p	CLIP-seq
MIRT972631	hsa-miR-3607-3p	CLIP-seq
MIRT2222647	hsa-miR-372	CLIP-seq
MIRT2222648	hsa-miR-373	CLIP-seq
MIRT2222649	hsa-miR-3916	CLIP-seq
MIRT2222650	hsa-miR-3919	CLIP-seq
MIRT2222651	hsa-miR-3942-3p	CLIP-seq
MIRT972634	hsa-miR-3974	CLIP-seq
MIRT972635	hsa-miR-3976	CLIP-seq
MIRT2222652	hsa-miR-4302	CLIP-seq
MIRT972637	hsa-miR-4433	CLIP-seq
MIRT2222653	hsa-miR-4436b-5p	CLIP-seq
MIRT972638	hsa-miR-4459	CLIP-seq
MIRT2222654	hsa-miR-452	CLIP-seq
MIRT2222655	hsa-miR-4676-3p	CLIP-seq
MIRT972639	hsa-miR-4729	CLIP-seq
MIRT2222656	hsa-miR-4755-3p	CLIP-seq
MIRT2222657	hsa-miR-4756-3p	CLIP-seq
MIRT972640	hsa-miR-4768-3p	CLIP-seq
MIRT2222658	hsa-miR-4803	CLIP-seq
MIRT2222659	hsa-miR-519a	CLIP-seq
MIRT2222660	hsa-miR-519b-3p	CLIP-seq
MIRT2222661	hsa-miR-519c-3p	CLIP-seq
MIRT2222662	hsa-miR-520a-3p	CLIP-seq
MIRT2222663	hsa-miR-520b	CLIP-seq
MIRT2222664	hsa-miR-520c-3p	CLIP-seq
MIRT2222665	hsa-miR-520d-3p	CLIP-seq
MIRT2222666	hsa-miR-520e	CLIP-seq
MIRT2222667	hsa-miR-548a-5p	CLIP-seq
MIRT2222668	hsa-miR-548ab	CLIP-seq
MIRT2222669	hsa-miR-548ac	CLIP-seq
MIRT2222670	hsa-miR-548ak	CLIP-seq
MIRT2222671	hsa-miR-548b-5p	CLIP-seq
MIRT2222672	hsa-miR-548c-5p	CLIP-seq
MIRT2222673	hsa-miR-548d-3p	CLIP-seq
MIRT2222674	hsa-miR-548d-5p	CLIP-seq
MIRT2222675	hsa-miR-548h	CLIP-seq
MIRT2222676	hsa-miR-548i	CLIP-seq
MIRT2222677	hsa-miR-548j	CLIP-seq
MIRT2222678	hsa-miR-548k	CLIP-seq
MIRT2222679	hsa-miR-548l	CLIP-seq
MIRT2222680	hsa-miR-548w	CLIP-seq
MIRT2222681	hsa-miR-548y	CLIP-seq
MIRT2222682	hsa-miR-548z	CLIP-seq
MIRT972642	hsa-miR-553	CLIP-seq
MIRT2222683	hsa-miR-559	CLIP-seq
MIRT2222684	hsa-miR-648	CLIP-seq
MIRT2222685	hsa-miR-759	CLIP-seq
MIRT2222686	hsa-miR-873	CLIP-seq
MIRT2222687	hsa-miR-888	CLIP-seq
MIRT972644	hsa-miR-96	CLIP-seq
MIRT2449002	hsa-miR-4282	CLIP-seq
MIRT2526274	hsa-miR-1179	CLIP-seq
MIRT2526275	hsa-miR-1183	CLIP-seq
MIRT2526276	hsa-miR-1208	CLIP-seq
MIRT972620	hsa-miR-1253	CLIP-seq
MIRT2526277	hsa-miR-129-3p	CLIP-seq
MIRT2526278	hsa-miR-134	CLIP-seq
MIRT2526279	hsa-miR-148a	CLIP-seq
MIRT2526280	hsa-miR-148b	CLIP-seq
MIRT2526281	hsa-miR-152	CLIP-seq
MIRT2526282	hsa-miR-15a	CLIP-seq
MIRT2526283	hsa-miR-15b	CLIP-seq
MIRT2526284	hsa-miR-16	CLIP-seq
MIRT2526285	hsa-miR-1915	CLIP-seq
MIRT2526286	hsa-miR-195	CLIP-seq
MIRT2526287	hsa-miR-196a	CLIP-seq
MIRT2526288	hsa-miR-196b	CLIP-seq
MIRT2526289	hsa-miR-2052	CLIP-seq
MIRT2526290	hsa-miR-2054	CLIP-seq
MIRT972624	hsa-miR-30a	CLIP-seq
MIRT972625	hsa-miR-30b	CLIP-seq
MIRT972626	hsa-miR-30c	CLIP-seq
MIRT972627	hsa-miR-30d	CLIP-seq
MIRT972628	hsa-miR-30e	CLIP-seq
MIRT2526291	hsa-miR-3118	CLIP-seq
MIRT972629	hsa-miR-3120-3p	CLIP-seq
MIRT2526292	hsa-miR-3123	CLIP-seq
MIRT2526293	hsa-miR-3124-3p	CLIP-seq
MIRT2222645	hsa-miR-3125	CLIP-seq
MIRT2526294	hsa-miR-3136-5p	CLIP-seq
MIRT2526295	hsa-miR-3144-5p	CLIP-seq
MIRT2222646	hsa-miR-3148	CLIP-seq
MIRT2526296	hsa-miR-3162-5p	CLIP-seq
MIRT2526297	hsa-miR-3164	CLIP-seq
MIRT2526298	hsa-miR-3183	CLIP-seq
MIRT2526299	hsa-miR-3184	CLIP-seq
MIRT2526300	hsa-miR-3199	CLIP-seq
MIRT2526301	hsa-miR-331-5p	CLIP-seq
MIRT2526302	hsa-miR-33a	CLIP-seq
MIRT2526303	hsa-miR-33b	CLIP-seq
MIRT2526304	hsa-miR-34c-3p	CLIP-seq
MIRT972630	hsa-miR-3545-3p	CLIP-seq
MIRT972631	hsa-miR-3607-3p	CLIP-seq
MIRT972632	hsa-miR-3613-5p	CLIP-seq
MIRT2526305	hsa-miR-3652	CLIP-seq
MIRT2526306	hsa-miR-3667-3p	CLIP-seq
MIRT2526307	hsa-miR-3671	CLIP-seq
MIRT2526308	hsa-miR-3685	CLIP-seq
MIRT2526309	hsa-miR-380	CLIP-seq
MIRT2526310	hsa-miR-384	CLIP-seq
MIRT972633	hsa-miR-3908	CLIP-seq
MIRT2222649	hsa-miR-3916	CLIP-seq
MIRT2526311	hsa-miR-3924	CLIP-seq
MIRT2526312	hsa-miR-3925-5p	CLIP-seq
MIRT2526313	hsa-miR-3927	CLIP-seq
MIRT972634	hsa-miR-3974	CLIP-seq
MIRT2526314	hsa-miR-423-5p	CLIP-seq
MIRT2526315	hsa-miR-424	CLIP-seq
MIRT972636	hsa-miR-4251	CLIP-seq
MIRT2526316	hsa-miR-4297	CLIP-seq
MIRT2526317	hsa-miR-4430	CLIP-seq
MIRT972637	hsa-miR-4433	CLIP-seq
MIRT2526318	hsa-miR-4439	CLIP-seq
MIRT972638	hsa-miR-4459	CLIP-seq
MIRT2526319	hsa-miR-4461	CLIP-seq
MIRT2526320	hsa-miR-4495	CLIP-seq
MIRT2526321	hsa-miR-450b-3p	CLIP-seq
MIRT2526322	hsa-miR-4513	CLIP-seq
MIRT2526323	hsa-miR-4515	CLIP-seq
MIRT2222654	hsa-miR-452	CLIP-seq
MIRT2526324	hsa-miR-4524	CLIP-seq
MIRT2526325	hsa-miR-4652-3p	CLIP-seq
MIRT2222655	hsa-miR-4676-3p	CLIP-seq
MIRT2526326	hsa-miR-4687-5p	CLIP-seq
MIRT2526327	hsa-miR-4697-3p	CLIP-seq
MIRT2526328	hsa-miR-4713-3p	CLIP-seq
MIRT2526329	hsa-miR-4723-3p	CLIP-seq
MIRT2526330	hsa-miR-4726-3p	CLIP-seq
MIRT972639	hsa-miR-4729	CLIP-seq
MIRT2526331	hsa-miR-4732-5p	CLIP-seq
MIRT972640	hsa-miR-4768-3p	CLIP-seq
MIRT972641	hsa-miR-4786-3p	CLIP-seq
MIRT2222658	hsa-miR-4803	CLIP-seq
MIRT2526332	hsa-miR-497	CLIP-seq
MIRT2526333	hsa-miR-503	CLIP-seq
MIRT2222667	hsa-miR-548a-5p	CLIP-seq
MIRT2222668	hsa-miR-548ab	CLIP-seq
MIRT2222669	hsa-miR-548ac	CLIP-seq
MIRT2222670	hsa-miR-548ak	CLIP-seq
MIRT2222671	hsa-miR-548b-5p	CLIP-seq
MIRT2222672	hsa-miR-548c-5p	CLIP-seq
MIRT2222673	hsa-miR-548d-3p	CLIP-seq
MIRT2222674	hsa-miR-548d-5p	CLIP-seq
MIRT2222675	hsa-miR-548h	CLIP-seq
MIRT2222676	hsa-miR-548i	CLIP-seq
MIRT2222677	hsa-miR-548j	CLIP-seq
MIRT2222678	hsa-miR-548k	CLIP-seq
MIRT2222679	hsa-miR-548l	CLIP-seq
MIRT2526334	hsa-miR-548n	CLIP-seq
MIRT2526335	hsa-miR-548t	CLIP-seq
MIRT2526336	hsa-miR-548u	CLIP-seq
MIRT2222680	hsa-miR-548w	CLIP-seq
MIRT2222681	hsa-miR-548y	CLIP-seq
MIRT2222682	hsa-miR-548z	CLIP-seq
MIRT972642	hsa-miR-553	CLIP-seq
MIRT2222683	hsa-miR-559	CLIP-seq
MIRT2526337	hsa-miR-638	CLIP-seq
MIRT972643	hsa-miR-646	CLIP-seq
MIRT2526338	hsa-miR-659	CLIP-seq
MIRT2526339	hsa-miR-769-3p	CLIP-seq
MIRT2526340	hsa-miR-877	CLIP-seq
MIRT2222687	hsa-miR-888	CLIP-seq
MIRT2526274	hsa-miR-1179	CLIP-seq
MIRT2526275	hsa-miR-1183	CLIP-seq
MIRT2526276	hsa-miR-1208	CLIP-seq
MIRT972620	hsa-miR-1253	CLIP-seq
MIRT2526277	hsa-miR-129-3p	CLIP-seq
MIRT2526279	hsa-miR-148a	CLIP-seq
MIRT2526280	hsa-miR-148b	CLIP-seq
MIRT2526281	hsa-miR-152	CLIP-seq
MIRT2526282	hsa-miR-15a	CLIP-seq
MIRT2526283	hsa-miR-15b	CLIP-seq
MIRT2526284	hsa-miR-16	CLIP-seq
MIRT2526285	hsa-miR-1915	CLIP-seq
MIRT2526286	hsa-miR-195	CLIP-seq
MIRT2526287	hsa-miR-196a	CLIP-seq
MIRT2526288	hsa-miR-196b	CLIP-seq
MIRT2526289	hsa-miR-2052	CLIP-seq
MIRT2526290	hsa-miR-2054	CLIP-seq
MIRT972624	hsa-miR-30a	CLIP-seq
MIRT972625	hsa-miR-30b	CLIP-seq
MIRT972626	hsa-miR-30c	CLIP-seq
MIRT972627	hsa-miR-30d	CLIP-seq
MIRT972628	hsa-miR-30e	CLIP-seq
MIRT972629	hsa-miR-3120-3p	CLIP-seq
MIRT2526292	hsa-miR-3123	CLIP-seq
MIRT2526293	hsa-miR-3124-3p	CLIP-seq
MIRT2222645	hsa-miR-3125	CLIP-seq
MIRT2222646	hsa-miR-3148	CLIP-seq
MIRT2526296	hsa-miR-3162-5p	CLIP-seq
MIRT2526298	hsa-miR-3183	CLIP-seq
MIRT2526300	hsa-miR-3199	CLIP-seq
MIRT2526301	hsa-miR-331-5p	CLIP-seq
MIRT2526302	hsa-miR-33a	CLIP-seq
MIRT2526303	hsa-miR-33b	CLIP-seq
MIRT2526304	hsa-miR-34c-3p	CLIP-seq
MIRT972630	hsa-miR-3545-3p	CLIP-seq
MIRT972631	hsa-miR-3607-3p	CLIP-seq
MIRT972632	hsa-miR-3613-5p	CLIP-seq
MIRT2526305	hsa-miR-3652	CLIP-seq
MIRT2526306	hsa-miR-3667-3p	CLIP-seq
MIRT2526307	hsa-miR-3671	CLIP-seq
MIRT2526308	hsa-miR-3685	CLIP-seq
MIRT2526309	hsa-miR-380	CLIP-seq
MIRT2526310	hsa-miR-384	CLIP-seq
MIRT972633	hsa-miR-3908	CLIP-seq
MIRT2222649	hsa-miR-3916	CLIP-seq
MIRT2526311	hsa-miR-3924	CLIP-seq
MIRT2526312	hsa-miR-3925-5p	CLIP-seq
MIRT2526313	hsa-miR-3927	CLIP-seq
MIRT972634	hsa-miR-3974	CLIP-seq
MIRT2526315	hsa-miR-424	CLIP-seq
MIRT972636	hsa-miR-4251	CLIP-seq
MIRT2526316	hsa-miR-4297	CLIP-seq
MIRT2526317	hsa-miR-4430	CLIP-seq
MIRT972637	hsa-miR-4433	CLIP-seq
MIRT972638	hsa-miR-4459	CLIP-seq
MIRT2526319	hsa-miR-4461	CLIP-seq
MIRT2526320	hsa-miR-4495	CLIP-seq
MIRT2526321	hsa-miR-450b-3p	CLIP-seq
MIRT2526323	hsa-miR-4515	CLIP-seq
MIRT2222654	hsa-miR-452	CLIP-seq
MIRT2526324	hsa-miR-4524	CLIP-seq
MIRT2526325	hsa-miR-4652-3p	CLIP-seq
MIRT2222655	hsa-miR-4676-3p	CLIP-seq
MIRT2526326	hsa-miR-4687-5p	CLIP-seq
MIRT2526327	hsa-miR-4697-3p	CLIP-seq
MIRT2526328	hsa-miR-4713-3p	CLIP-seq
MIRT2526329	hsa-miR-4723-3p	CLIP-seq
MIRT2526330	hsa-miR-4726-3p	CLIP-seq
MIRT972639	hsa-miR-4729	CLIP-seq
MIRT2526331	hsa-miR-4732-5p	CLIP-seq
MIRT972640	hsa-miR-4768-3p	CLIP-seq
MIRT972641	hsa-miR-4786-3p	CLIP-seq
MIRT2526332	hsa-miR-497	CLIP-seq
MIRT2526333	hsa-miR-503	CLIP-seq
MIRT2222667	hsa-miR-548a-5p	CLIP-seq
MIRT2680386	hsa-miR-548aa	CLIP-seq
MIRT2222668	hsa-miR-548ab	CLIP-seq
MIRT2222669	hsa-miR-548ac	CLIP-seq
MIRT2222670	hsa-miR-548ak	CLIP-seq
MIRT2222671	hsa-miR-548b-5p	CLIP-seq
MIRT2222672	hsa-miR-548c-5p	CLIP-seq
MIRT2222673	hsa-miR-548d-3p	CLIP-seq
MIRT2222674	hsa-miR-548d-5p	CLIP-seq
MIRT2222675	hsa-miR-548h	CLIP-seq
MIRT2222676	hsa-miR-548i	CLIP-seq
MIRT2222677	hsa-miR-548j	CLIP-seq
MIRT2222678	hsa-miR-548k	CLIP-seq
MIRT2222679	hsa-miR-548l	CLIP-seq
MIRT2526334	hsa-miR-548n	CLIP-seq
MIRT2526335	hsa-miR-548t	CLIP-seq
MIRT2526336	hsa-miR-548u	CLIP-seq
MIRT2222680	hsa-miR-548w	CLIP-seq
MIRT2222681	hsa-miR-548y	CLIP-seq
MIRT2222682	hsa-miR-548z	CLIP-seq
MIRT972642	hsa-miR-553	CLIP-seq
MIRT2222683	hsa-miR-559	CLIP-seq
MIRT2526337	hsa-miR-638	CLIP-seq
MIRT972643	hsa-miR-646	CLIP-seq
MIRT2526338	hsa-miR-659	CLIP-seq
MIRT2526339	hsa-miR-769-3p	CLIP-seq
MIRT2526340	hsa-miR-877	CLIP-seq
MIRT2222687	hsa-miR-888	CLIP-seq

Show/Hide all (35)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000145	Component	Exocyst	IBA
GO:0000145	Component	Exocyst	IEA
GO:0000145	Component	Exocyst	NAS	22420621
GO:0000281	Process	Mitotic cytokinesis	NAS	22420621
GO:0005515	Function	Protein binding	IPI	17043677, 18329369, 18480549, 19885391, 20579884, 21241894, 21658605, 24056301, 25244576, 25594178, 26760201, 27173435, 28514442, 31413325, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	26638075
GO:0005813	Component	Centrosome	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005902	Component	Microvillus	IEA
GO:0006887	Process	Exocytosis	IBA
GO:0006887	Process	Exocytosis	IEA
GO:0006893	Process	Golgi to plasma membrane transport	IBA
GO:0006904	Process	Vesicle docking involved in exocytosis	IEA
GO:0006904	Process	Vesicle docking involved in exocytosis	NAS	22420621
GO:0007268	Process	Chemical synaptic transmission	IBA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016241	Process	Regulation of macroautophagy	TAS	21241894
GO:0030165	Function	PDZ domain binding	IEA
GO:0032584	Component	Growth cone membrane	IBA
GO:0032584	Component	Growth cone membrane	IEA
GO:0035748	Component	Myelin sheath abaxonal region	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0045202	Component	Synapse	IBA
GO:0048341	Process	Paraxial mesoderm formation	IEA
GO:0071806	Process	Protein transmembrane transport	IEA
GO:0090148	Process	Membrane fission	NAS	22420621
GO:0090522	Process	Vesicle tethering involved in exocytosis	IEA
GO:0090522	Process	Vesicle tethering involved in exocytosis	NAS	22420621
GO:0090543	Component	Flemming body	IEA

MIM	HGNC	e!Ensembl
608185	30389	ENSG00000131558

Q96A65

Protein name

Exocyst complex component 4 (Exocyst complex component Sec8)

Protein function

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

PDB

7PC5

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04048	Sec8_exocyst	27 → 144	Sec8 exocyst complex component specific domain	Domain

Sequence

MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEAYEKCDRDLDE
LIVQHYTELTTAIRTYQSITERITNSRNKIKQVKENLLSCKMLLHCKRDELRKLWIEGIE
HKHVLNLLDEIENIKQVPQKLEQCMASKHYLSATDMLVSAVESLEGPLLQVEGLSDLRLE
LHSKKMNLHLVLIDELHRHLYIKSTSRVVQRNKEKGKISSLVKDASVPLIDVTNLPTPRK
FLDTSHYSTAGSSSVREINLQDIKEDLELDPEENSTLFMGILIKGLAKLKKIPETVKAII
ERLEQELKQIVKRSTTQVADSGYQRGENVTVENQPRLLLELLELLFDKFNAVAAAHSVVL
GYLQDTVVTPLTQQEDIKLYDMADVWVKIQDVLQMLLTEYLDMKNTRTASEPSAQLSYAS
TGREFAAFFAKKKPQRPKNSLFKFESSSHAISMSAYLREQRRELYSRSGELQGGPDDNLI
EGGGTKFVCKPGARNITVIFHPLLRFIQEIEHALGLGPAKQCPLREFLTVYIKNIFLNQV
LAEINKEIEGVTKTSDPLKILANADTMKVLGVQRPLLQSTIIVEKTVQDLLNLMHDLSAY
SDQFLNMVCVKLQEYKDTCTAAYRGIVQSEEKLVISASWAKDDDISRLLKSLPNWMNMAQ
PKQLRPKREEEEDFIRAAFGKESEVLIGNLGDKLIPPQDILRDVSDLKALANMHESLEWL
ASRTKSAFSNLSTSQMLSPAQDSHTNTDLPPVSEQIMQTLSELAKSFQDMADRCLLVLHL
EVRVHCFHYLIPLAKEGNYAIVANVESMDYDPLVVKLNKDISAIEEAMSASLQQHKFQYI
FEGLGHLISCILINGAQYFRRISESGIKKMCRNIFVLQQNLTNITMSREADLDFARQYYE
MLYNTADELLNLVVDQGVKYTELEYIHALTLLHRSQTGVGELTTQNTRLQRLKEIICEQA
AIKQATKDKKITTV

Sequence length

974

Interactions

View interactions

	KEGG		Reactome
	Salmonella infection		Insulin processing VxPx cargo-targeting to cilium

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Meckel-Gruber syndrome	Likely pathogenic	rs730882233	RCV000162153

Show/Hide Text Mining Associations (17)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Alzheimer Disease	Associate	23978990
Arthritis Rheumatoid	Associate	15880602
Charcot Marie Tooth disease Type 2B	Associate	32741968
Colorectal Neoplasms	Associate	20126641, 31525256
Diabetes Mellitus	Associate	24299491
Diabetes Mellitus Type 2	Associate	18498660
Drug Related Side Effects and Adverse Reactions	Associate	19129090
Glaucoma Open Angle	Associate	30317457
Kidney Diseases	Associate	20126641
Meckel syndrome type 1	Associate	23169490
Neoplasm Metastasis	Stimulate	35471457
Neoplasms	Associate	24299491, 31525256
Nerve Degeneration	Associate	24299491
Otitis Media	Associate	19728873
Polycystic Kidney Autosomal Dominant	Associate	10747091
Stomach Neoplasms	Stimulate	35471457
Warts	Associate	31892232

EXOC4 (exocyst complex component 4)