Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	5982
Gene name Gene Name - the full gene name approved by the HGNC.	Replication factor C subunit 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RFC2
Synonyms (NCBI Gene) Gene synonyms aliases	RFC40
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q11.23
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor

Show/Hide all(286)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023820	hsa-miR-1-3p	Proteomics	18668040
MIRT048154	hsa-miR-196a-5p	CLASH	23622248
MIRT045679	hsa-miR-149-5p	CLASH	23622248
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	19536157
MIRT629587	hsa-miR-767-5p	HITS-CLIP	19536157
MIRT629583	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	19536157
MIRT629587	hsa-miR-767-5p	HITS-CLIP	19536157
MIRT629583	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT629597	hsa-miR-5197-5p	HITS-CLIP	19536157
MIRT629589	hsa-miR-183-5p	HITS-CLIP	19536157
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	19536157
MIRT629587	hsa-miR-767-5p	HITS-CLIP	19536157
MIRT629583	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	19536157
MIRT629587	hsa-miR-767-5p	HITS-CLIP	19536157
MIRT629583	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT681296	hsa-miR-512-5p	HITS-CLIP	23706177
MIRT681295	hsa-miR-510-5p	HITS-CLIP	23706177
MIRT681294	hsa-miR-4695-5p	HITS-CLIP	23706177
MIRT681293	hsa-miR-4779	HITS-CLIP	23706177
MIRT681292	hsa-miR-3929	HITS-CLIP	23706177
MIRT681291	hsa-miR-4419b	HITS-CLIP	23706177
MIRT681290	hsa-miR-4478	HITS-CLIP	23706177
MIRT681289	hsa-miR-3614-5p	HITS-CLIP	23706177
MIRT681288	hsa-miR-6500-3p	HITS-CLIP	23706177
MIRT681287	hsa-miR-4768-3p	HITS-CLIP	23706177
MIRT681286	hsa-miR-4459	HITS-CLIP	23706177
MIRT681285	hsa-miR-4433a-3p	HITS-CLIP	23706177
MIRT681284	hsa-miR-3664-3p	HITS-CLIP	23706177
MIRT681283	hsa-miR-7162-3p	HITS-CLIP	23706177
MIRT681282	hsa-miR-1225-3p	HITS-CLIP	23706177
MIRT681281	hsa-miR-1233-3p	HITS-CLIP	23706177
MIRT681280	hsa-miR-3975	HITS-CLIP	23706177
MIRT681279	hsa-miR-2467-5p	HITS-CLIP	23706177
MIRT681278	hsa-miR-485-5p	HITS-CLIP	23706177
MIRT681277	hsa-miR-6884-5p	HITS-CLIP	23706177
MIRT681276	hsa-miR-3188	HITS-CLIP	23706177
MIRT681275	hsa-let-7a-5p	HITS-CLIP	23706177
MIRT681274	hsa-let-7b-5p	HITS-CLIP	23706177
MIRT681273	hsa-let-7c-5p	HITS-CLIP	23706177
MIRT681272	hsa-let-7d-5p	HITS-CLIP	23706177
MIRT681271	hsa-let-7e-5p	HITS-CLIP	23706177
MIRT681270	hsa-let-7f-5p	HITS-CLIP	23706177
MIRT681269	hsa-let-7g-5p	HITS-CLIP	23706177
MIRT681268	hsa-let-7i-5p	HITS-CLIP	23706177
MIRT681267	hsa-miR-4458	HITS-CLIP	23706177
MIRT681266	hsa-miR-4500	HITS-CLIP	23706177
MIRT681265	hsa-miR-98-5p	HITS-CLIP	23706177
MIRT681264	hsa-miR-202-3p	HITS-CLIP	23706177
MIRT681263	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681262	hsa-miR-6086	HITS-CLIP	23706177
MIRT681261	hsa-miR-7160-5p	HITS-CLIP	23706177
MIRT681260	hsa-miR-6894-5p	HITS-CLIP	23706177
MIRT681259	hsa-miR-4266	HITS-CLIP	23706177
MIRT681258	hsa-miR-6807-5p	HITS-CLIP	23706177
MIRT681257	hsa-miR-6765-5p	HITS-CLIP	23706177
MIRT681256	hsa-miR-1304-5p	HITS-CLIP	23706177
MIRT681255	hsa-miR-1273g-5p	HITS-CLIP	23706177
MIRT681254	hsa-miR-665	HITS-CLIP	23706177
MIRT629597	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT629596	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629595	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629594	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629593	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629592	hsa-miR-3666	HITS-CLIP	23824327
MIRT629591	hsa-miR-4295	HITS-CLIP	23824327
MIRT629590	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629589	hsa-miR-183-5p	HITS-CLIP	23824327
MIRT629587	hsa-miR-767-5p	HITS-CLIP	23824327
MIRT629584	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629583	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT629582	hsa-miR-3652	HITS-CLIP	23824327
MIRT629581	hsa-miR-4430	HITS-CLIP	23824327
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT629597	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT629596	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629595	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629594	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629593	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629592	hsa-miR-3666	HITS-CLIP	23824327
MIRT629591	hsa-miR-4295	HITS-CLIP	23824327
MIRT629590	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629589	hsa-miR-183-5p	HITS-CLIP	23824327
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	23824327
MIRT629587	hsa-miR-767-5p	HITS-CLIP	23824327
MIRT629586	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629585	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629584	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629583	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT629582	hsa-miR-3652	HITS-CLIP	23824327
MIRT629581	hsa-miR-4430	HITS-CLIP	23824327
MIRT629580	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	19536157
MIRT629587	hsa-miR-767-5p	HITS-CLIP	19536157
MIRT629583	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	19536157
MIRT629587	hsa-miR-767-5p	HITS-CLIP	19536157
MIRT629583	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT629597	hsa-miR-5197-5p	HITS-CLIP	19536157
MIRT629589	hsa-miR-183-5p	HITS-CLIP	19536157
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	19536157
MIRT629587	hsa-miR-767-5p	HITS-CLIP	19536157
MIRT629583	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	19536157
MIRT629587	hsa-miR-767-5p	HITS-CLIP	19536157
MIRT629583	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT681296	hsa-miR-512-5p	HITS-CLIP	23706177
MIRT681295	hsa-miR-510-5p	HITS-CLIP	23706177
MIRT681294	hsa-miR-4695-5p	HITS-CLIP	23706177
MIRT681293	hsa-miR-4779	HITS-CLIP	23706177
MIRT681292	hsa-miR-3929	HITS-CLIP	23706177
MIRT681291	hsa-miR-4419b	HITS-CLIP	23706177
MIRT681290	hsa-miR-4478	HITS-CLIP	23706177
MIRT681289	hsa-miR-3614-5p	HITS-CLIP	23706177
MIRT681288	hsa-miR-6500-3p	HITS-CLIP	23706177
MIRT681287	hsa-miR-4768-3p	HITS-CLIP	23706177
MIRT681286	hsa-miR-4459	HITS-CLIP	23706177
MIRT681285	hsa-miR-4433a-3p	HITS-CLIP	23706177
MIRT681284	hsa-miR-3664-3p	HITS-CLIP	23706177
MIRT681283	hsa-miR-7162-3p	HITS-CLIP	23706177
MIRT681282	hsa-miR-1225-3p	HITS-CLIP	23706177
MIRT681281	hsa-miR-1233-3p	HITS-CLIP	23706177
MIRT681280	hsa-miR-3975	HITS-CLIP	23706177
MIRT681279	hsa-miR-2467-5p	HITS-CLIP	23706177
MIRT681278	hsa-miR-485-5p	HITS-CLIP	23706177
MIRT681277	hsa-miR-6884-5p	HITS-CLIP	23706177
MIRT681276	hsa-miR-3188	HITS-CLIP	23706177
MIRT681275	hsa-let-7a-5p	HITS-CLIP	23706177
MIRT681274	hsa-let-7b-5p	HITS-CLIP	23706177
MIRT681273	hsa-let-7c-5p	HITS-CLIP	23706177
MIRT681272	hsa-let-7d-5p	HITS-CLIP	23706177
MIRT681271	hsa-let-7e-5p	HITS-CLIP	23706177
MIRT681270	hsa-let-7f-5p	HITS-CLIP	23706177
MIRT681269	hsa-let-7g-5p	HITS-CLIP	23706177
MIRT681268	hsa-let-7i-5p	HITS-CLIP	23706177
MIRT681267	hsa-miR-4458	HITS-CLIP	23706177
MIRT681266	hsa-miR-4500	HITS-CLIP	23706177
MIRT681265	hsa-miR-98-5p	HITS-CLIP	23706177
MIRT681264	hsa-miR-202-3p	HITS-CLIP	23706177
MIRT681263	hsa-miR-377-5p	HITS-CLIP	23706177
MIRT681262	hsa-miR-6086	HITS-CLIP	23706177
MIRT681261	hsa-miR-7160-5p	HITS-CLIP	23706177
MIRT681260	hsa-miR-6894-5p	HITS-CLIP	23706177
MIRT681259	hsa-miR-4266	HITS-CLIP	23706177
MIRT681258	hsa-miR-6807-5p	HITS-CLIP	23706177
MIRT681257	hsa-miR-6765-5p	HITS-CLIP	23706177
MIRT681256	hsa-miR-1304-5p	HITS-CLIP	23706177
MIRT681255	hsa-miR-1273g-5p	HITS-CLIP	23706177
MIRT681254	hsa-miR-665	HITS-CLIP	23706177
MIRT629597	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT629596	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629595	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629594	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629593	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629592	hsa-miR-3666	HITS-CLIP	23824327
MIRT629591	hsa-miR-4295	HITS-CLIP	23824327
MIRT629590	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629589	hsa-miR-183-5p	HITS-CLIP	23824327
MIRT629587	hsa-miR-767-5p	HITS-CLIP	23824327
MIRT629584	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629583	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT629582	hsa-miR-3652	HITS-CLIP	23824327
MIRT629581	hsa-miR-4430	HITS-CLIP	23824327
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT629597	hsa-miR-5197-5p	HITS-CLIP	23824327
MIRT629596	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT629595	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT629594	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT629593	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT629592	hsa-miR-3666	HITS-CLIP	23824327
MIRT629591	hsa-miR-4295	HITS-CLIP	23824327
MIRT629590	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT629589	hsa-miR-183-5p	HITS-CLIP	23824327
MIRT629588	hsa-miR-4999-3p	HITS-CLIP	23824327
MIRT629587	hsa-miR-767-5p	HITS-CLIP	23824327
MIRT629586	hsa-miR-3135b	HITS-CLIP	23824327
MIRT629585	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT629584	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT629583	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT629582	hsa-miR-3652	HITS-CLIP	23824327
MIRT629581	hsa-miR-4430	HITS-CLIP	23824327
MIRT629580	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT629579	hsa-miR-6836-3p	HITS-CLIP	23824327
MIRT629578	hsa-miR-3152-5p	HITS-CLIP	23824327
MIRT1301523	hsa-miR-224	CLIP-seq
MIRT1301524	hsa-miR-4775	CLIP-seq
MIRT1301525	hsa-miR-590-3p	CLIP-seq
MIRT1301526	hsa-miR-1254	CLIP-seq
MIRT1301527	hsa-miR-1343	CLIP-seq
MIRT1301528	hsa-miR-141	CLIP-seq
MIRT1301529	hsa-miR-200a	CLIP-seq
MIRT1301530	hsa-miR-2276	CLIP-seq
MIRT1301531	hsa-miR-2355-5p	CLIP-seq
MIRT1301532	hsa-miR-24	CLIP-seq
MIRT1301533	hsa-miR-3065-5p	CLIP-seq
MIRT1301534	hsa-miR-3116	CLIP-seq
MIRT1301535	hsa-miR-3194-5p	CLIP-seq
MIRT1301536	hsa-miR-3662	CLIP-seq
MIRT1301537	hsa-miR-3679-3p	CLIP-seq
MIRT1301538	hsa-miR-4252	CLIP-seq
MIRT1301539	hsa-miR-4284	CLIP-seq
MIRT1301540	hsa-miR-4435	CLIP-seq
MIRT1301541	hsa-miR-4691-3p	CLIP-seq
MIRT1301542	hsa-miR-4708-3p	CLIP-seq
MIRT1301543	hsa-miR-4772-3p	CLIP-seq
MIRT1301544	hsa-miR-495	CLIP-seq
MIRT1301545	hsa-miR-548u	CLIP-seq
MIRT1301546	hsa-miR-550a	CLIP-seq
MIRT1301547	hsa-miR-661	CLIP-seq
MIRT1301527	hsa-miR-1343	CLIP-seq
MIRT1301523	hsa-miR-224	CLIP-seq
MIRT1301531	hsa-miR-2355-5p	CLIP-seq
MIRT1301537	hsa-miR-3679-3p	CLIP-seq
MIRT1301539	hsa-miR-4284	CLIP-seq
MIRT2089520	hsa-miR-764	CLIP-seq
MIRT2314443	hsa-miR-1234	CLIP-seq
MIRT2314444	hsa-miR-125a-3p	CLIP-seq
MIRT2314445	hsa-miR-150	CLIP-seq
MIRT2314446	hsa-miR-342-5p	CLIP-seq
MIRT2314447	hsa-miR-3934	CLIP-seq
MIRT2314448	hsa-miR-4651	CLIP-seq
MIRT2314449	hsa-miR-4664-5p	CLIP-seq
MIRT2314450	hsa-miR-520g	CLIP-seq
MIRT2314451	hsa-miR-520h	CLIP-seq
MIRT2314452	hsa-miR-608	CLIP-seq
MIRT2314453	hsa-miR-640	CLIP-seq
MIRT2089520	hsa-miR-764	CLIP-seq
MIRT2393633	hsa-miR-122	CLIP-seq
MIRT2393634	hsa-miR-130a	CLIP-seq
MIRT2393635	hsa-miR-130b	CLIP-seq
MIRT2393636	hsa-miR-301a	CLIP-seq
MIRT2393637	hsa-miR-301b	CLIP-seq
MIRT2393638	hsa-miR-3650	CLIP-seq
MIRT2393639	hsa-miR-454	CLIP-seq
MIRT1301527	hsa-miR-1343	CLIP-seq
MIRT2458060	hsa-miR-3064-3p	CLIP-seq
MIRT2393633	hsa-miR-122	CLIP-seq
MIRT2393634	hsa-miR-130a	CLIP-seq
MIRT2393635	hsa-miR-130b	CLIP-seq
MIRT1301527	hsa-miR-1343	CLIP-seq
MIRT1301532	hsa-miR-24	CLIP-seq
MIRT2393636	hsa-miR-301a	CLIP-seq
MIRT2393637	hsa-miR-301b	CLIP-seq
MIRT2458060	hsa-miR-3064-3p	CLIP-seq
MIRT2393638	hsa-miR-3650	CLIP-seq
MIRT1301539	hsa-miR-4284	CLIP-seq
MIRT2393639	hsa-miR-454	CLIP-seq
MIRT2610856	hsa-miR-4735-5p	CLIP-seq
MIRT1301524	hsa-miR-4775	CLIP-seq
MIRT1301525	hsa-miR-590-3p	CLIP-seq
MIRT2393633	hsa-miR-122	CLIP-seq
MIRT2393634	hsa-miR-130a	CLIP-seq
MIRT2393635	hsa-miR-130b	CLIP-seq
MIRT1301527	hsa-miR-1343	CLIP-seq
MIRT1301532	hsa-miR-24	CLIP-seq
MIRT2393636	hsa-miR-301a	CLIP-seq
MIRT2393637	hsa-miR-301b	CLIP-seq
MIRT2458060	hsa-miR-3064-3p	CLIP-seq
MIRT2393638	hsa-miR-3650	CLIP-seq
MIRT1301539	hsa-miR-4284	CLIP-seq
MIRT2393639	hsa-miR-454	CLIP-seq
MIRT2610856	hsa-miR-4735-5p	CLIP-seq
MIRT1301543	hsa-miR-4772-3p	CLIP-seq
MIRT1301524	hsa-miR-4775	CLIP-seq
MIRT1301525	hsa-miR-590-3p	CLIP-seq

Show/Hide all(23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003689	Function	DNA clamp loader activity	IBA
GO:0003689	Function	DNA clamp loader activity	IDA	12930902
GO:0005515	Function	Protein binding	IPI	9488738, 15655353, 18499658, 32296183, 33961781
GO:0005524	Function	ATP binding	IEA
GO:0005524	Function	ATP binding	TAS	1313560
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005663	Component	DNA replication factor C complex	IBA
GO:0005663	Component	DNA replication factor C complex	IDA	9488738
GO:0005663	Component	DNA replication factor C complex	IPI	9488738
GO:0005694	Component	Chromosome	IEA
GO:0006260	Process	DNA replication	IEA
GO:0006261	Process	DNA-templated DNA replication	IBA
GO:0006261	Process	DNA-templated DNA replication	IDA	9488738
GO:0006281	Process	DNA repair	IBA
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0017116	Function	Single-stranded DNA helicase activity	IDA	12930902
GO:0019899	Function	Enzyme binding	IEA
GO:0031390	Component	Ctf18 RFC-like complex	IDA	12930902
GO:1900264	Process	Positive regulation of DNA-directed DNA polymerase activity	IDA	12930902

MIM	HGNC	e!Ensembl
600404	9970	ENSG00000049541

Protein

UniProt ID

P35250

Protein name

Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40)

Protein function

Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA

PDB

6VVO , 7Z6H , 8UI7 , 8UI8 , 8UI9 , 8UII , 8UMT , 8UMU , 8UMV , 8UMW , 8UMY , 8UN0 , 8UNJ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00004	AAA	72 → 193	ATPase family associated with various cellular activities (AAA)	Domain
PF08542	Rep_fac_C	258 → 343	Replication factor C C-terminal domain	Domain

Sequence

MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI
KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP
IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF
SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF
RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS

Sequence length

354

Interactions

View interactions

	KEGG		Reactome
	DNA replication Base excision repair Nucleotide excision repair Mismatch repair		Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere Activation of ATR in response to replication stress PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Regulation of TP53 Activity through Phosphorylation Polymerase switching G2/M DNA damage checkpoint

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Systemic lupus erythematosus	Systemic lupus erythematosus	N/A	N/A	GWAS

Show/Hide Text Mining Associations (21)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Carcinoma Hepatocellular	Stimulate	34022962
Choriocarcinoma	Stimulate	15846072
Colorectal Neoplasms	Associate	30658502, 37821801
Diabetes Mellitus Type 2	Associate	31797865
DNA Virus Infections	Associate	23112151
Esophageal Squamous Cell Carcinoma	Associate	31845510
Fanconi Anemia	Associate	34404366
Gestational Trophoblastic Disease	Stimulate	15846072
Glioblastoma	Associate	15494095
Glioma	Associate	35210438
Kidney Neoplasms	Associate	36189312
Myocardial Infarction	Associate	40587682
Neoplasm Metastasis	Associate	37821801
Neoplasms	Associate	35210438, 36189312, 37821801
Prostatic Neoplasms	Associate	37950047
Prostatic Neoplasms Castration Resistant	Stimulate	37950047
Sarcoma	Stimulate	35483337
Stomach Neoplasms	Associate	35791074
Uterine Cervical Dysplasia	Associate	34404366
Uterine Cervical Neoplasms	Associate	34404366
Williams Syndrome	Associate	17564965, 22608712, 25105779, 28098859

RFC2 (replication factor C subunit 2)