DPF2 (double PHD fingers 2)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 5977 |
| Gene name | Double PHD fingers 2 |
| Gene symbol | DPF2 |
| Synonyms (NCBI Gene) |
CSS7REQSMARCG2UBID4ubi-d4
|
| Chromosome | 11 |
| Chromosome location | 11q13.1 |
| Summary | The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival fa |
|
SNPs
SNP information provided by dbSNP.
5
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
miRNA
miRNA information provided by mirtarbase database.
519
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
34
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q92785 | ||||||||||||||||||||
| Protein name | Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem) | ||||||||||||||||||||
| Protein function | Plays an active role in transcriptional regulation by binding modified histones H3 and H4 (PubMed:27775714, PubMed:28533407). Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (PubMed:28533407). Might also have | ||||||||||||||||||||
| PDB | 3IUF , 5B79 , 5VDC , 6LTH , 6LTJ | ||||||||||||||||||||
| Family and domains |
Pfam
|
||||||||||||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. | ||||||||||||||||||||
| Sequence |
|
||||||||||||||||||||
| Sequence length | 391 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
||||||||
|
||||||||
|
Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
41
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||