DPF2 (double PHD fingers 2)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5977 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Double PHD fingers 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DPF2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CSS7, REQ, SMARCG2, UBID4, ubi-d4 |
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Chromosome
Chromosome number
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11 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11q13.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival fa |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | Q92785 | ||||||||||||||||||||
| Protein name | Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem) | ||||||||||||||||||||
| Protein function | Plays an active role in transcriptional regulation by binding modified histones H3 and H4 (PubMed:27775714, PubMed:28533407). Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (PubMed:28533407). Might also have | ||||||||||||||||||||
| PDB | 3IUF , 5B79 , 5VDC , 6LTH , 6LTJ | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 391 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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