Gene Gene information from NCBI Gene database.
Entrez ID 5939
Gene name RNA binding motif single stranded interacting protein 2
Gene symbol RBMS2
Synonyms (NCBI Gene)
SCR3
Chromosome 12
Chromosome location 12q13.3
Summary The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP
miRNA miRNA information provided by mirtarbase database.
1351
miRTarBase ID miRNA Experiments Reference
MIRT029628 hsa-miR-26b-5p Microarray 19088304
MIRT042413 hsa-miR-18b-5p CLASH 23622248
MIRT042145 hsa-miR-484 CLASH 23622248
MIRT700253 hsa-miR-548an HITS-CLIP 23313552
MIRT700252 hsa-miR-4484 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0003676 Function Nucleic acid binding IEA
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IEA
GO:0003723 Function RNA binding TAS 8041632
GO:0003730 Function MRNA 3'-UTR binding IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
602387 9909 ENSG00000076067
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q15434
Protein name RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3)
PDB 1X4E
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00076 RRM_1 58 123 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 137 203 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
Sequence
MLLSVTSRPGISTFGYNRNNKKPYVSLAQQMAPPSPSNSTPNSSSGSNGNDQLSKTNLYI
RGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKAS
GVQ
AQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFA
RMESTEKCEAIITHFNGKYIKTP
PGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPR
NADMGVMALTYDPTTALQNGFYPAPYNITPNRMLAQSALSPYLSSPVSSYQRVTQTSPLQ
VPNPSWMHHHSYLMQPSGSVLTPGMDHPISLQPASMMGPLTQQLGHLSLSSTGTYMPTAA
AMQGAYISQYTPVPSSSVSVEESSGQQNQVAVDAPSEHGVYSFQFNK
Sequence length 407
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
COLOR VISION DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CROHN'S DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Familial cancer of breast Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Carcinoma Renal Cell Associate 38058408
★☆☆☆☆
Found in Text Mining only
Inflammation Associate 25188723
★☆☆☆☆
Found in Text Mining only
Neoplasms Inhibit 38058408
★☆☆☆☆
Found in Text Mining only