GNB4 (G protein subunit beta 4)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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59345 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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G protein subunit beta 4 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GNB4 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CMTD1F, HG2B |
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Chromosome
Chromosome number
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3 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q26.33 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene enc |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||||||||||||
| UniProt ID | Q9HAV0 | ||||||||||||||||||||||||||||||||||||||||
| Protein name | Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4) | ||||||||||||||||||||||||||||||||||||||||
| Protein function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G prote | ||||||||||||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Strongly expressed in lung and placenta, whereas it is weakly expressed in brain and heart. Abundantly expressed in the axons and Schwann cells of peripheral nerves. {ECO:0000269|PubMed:11842130, ECO:0000269|PubMed:23434117}. | ||||||||||||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 340 | ||||||||||||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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