Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	59343
Gene name Gene Name - the full gene name approved by the HGNC.	SUMO specific peptidase 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SENP2
Synonyms (NCBI Gene) Gene synonyms aliases	AXAM2, SMT3IP2
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q27.2
Summary Summary of gene provided in NCBI Entrez Gene.	SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-cont

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miRTarBase ID	miRNA	Experiments	Reference
MIRT027689	hsa-miR-98-5p	Microarray	19088304
MIRT047781	hsa-miR-30d-5p	CLASH	23622248
MIRT1335729	hsa-let-7a	CLIP-seq
MIRT1335730	hsa-let-7b	CLIP-seq
MIRT1335731	hsa-let-7c	CLIP-seq
MIRT1335732	hsa-let-7d	CLIP-seq
MIRT1335733	hsa-let-7e	CLIP-seq
MIRT1335734	hsa-let-7f	CLIP-seq
MIRT1335735	hsa-let-7g	CLIP-seq
MIRT1335736	hsa-let-7i	CLIP-seq
MIRT1335737	hsa-miR-132	CLIP-seq
MIRT1335738	hsa-miR-142-3p	CLIP-seq
MIRT1335739	hsa-miR-1972	CLIP-seq
MIRT1335740	hsa-miR-202	CLIP-seq
MIRT1335741	hsa-miR-203	CLIP-seq
MIRT1335742	hsa-miR-212	CLIP-seq
MIRT1335743	hsa-miR-3130-3p	CLIP-seq
MIRT1335744	hsa-miR-3194-5p	CLIP-seq
MIRT1335745	hsa-miR-3613-3p	CLIP-seq
MIRT1335746	hsa-miR-3688-3p	CLIP-seq
MIRT1335747	hsa-miR-3691-3p	CLIP-seq
MIRT1335748	hsa-miR-3692	CLIP-seq
MIRT1335749	hsa-miR-3921	CLIP-seq
MIRT1335750	hsa-miR-3940-5p	CLIP-seq
MIRT1335751	hsa-miR-4276	CLIP-seq
MIRT1335752	hsa-miR-4436a	CLIP-seq
MIRT1335753	hsa-miR-4458	CLIP-seq
MIRT1335754	hsa-miR-4494	CLIP-seq
MIRT1335755	hsa-miR-4500	CLIP-seq
MIRT1335756	hsa-miR-4507	CLIP-seq
MIRT1335757	hsa-miR-455-3p	CLIP-seq
MIRT1335758	hsa-miR-4650-5p	CLIP-seq
MIRT1335759	hsa-miR-4653-5p	CLIP-seq
MIRT1335760	hsa-miR-4659a-3p	CLIP-seq
MIRT1335761	hsa-miR-4659b-3p	CLIP-seq
MIRT1335762	hsa-miR-4677-3p	CLIP-seq
MIRT1335763	hsa-miR-4679	CLIP-seq
MIRT1335764	hsa-miR-4687-5p	CLIP-seq
MIRT1335765	hsa-miR-4719	CLIP-seq
MIRT1335766	hsa-miR-4759	CLIP-seq
MIRT1335767	hsa-miR-4766-5p	CLIP-seq
MIRT1335768	hsa-miR-4793-3p	CLIP-seq
MIRT1335769	hsa-miR-488	CLIP-seq
MIRT1335770	hsa-miR-499a-5p	CLIP-seq
MIRT1335771	hsa-miR-513a-3p	CLIP-seq
MIRT1335772	hsa-miR-520d-5p	CLIP-seq
MIRT1335773	hsa-miR-524-5p	CLIP-seq
MIRT1335774	hsa-miR-548an	CLIP-seq
MIRT1335775	hsa-miR-617	CLIP-seq
MIRT1335776	hsa-miR-654-3p	CLIP-seq
MIRT1335777	hsa-miR-98	CLIP-seq
MIRT2099264	hsa-miR-1226	CLIP-seq
MIRT2099265	hsa-miR-1261	CLIP-seq
MIRT2099266	hsa-miR-129-5p	CLIP-seq
MIRT2099267	hsa-miR-18a	CLIP-seq
MIRT2099268	hsa-miR-18b	CLIP-seq
MIRT2099269	hsa-miR-1976	CLIP-seq
MIRT2099270	hsa-miR-214	CLIP-seq
MIRT2099271	hsa-miR-28-3p	CLIP-seq
MIRT2099272	hsa-miR-3074-3p	CLIP-seq
MIRT2099273	hsa-miR-3121-3p	CLIP-seq
MIRT2099274	hsa-miR-3133	CLIP-seq
MIRT2099275	hsa-miR-3143	CLIP-seq
MIRT2099276	hsa-miR-3180-5p	CLIP-seq
MIRT1335745	hsa-miR-3613-3p	CLIP-seq
MIRT2099277	hsa-miR-3619-5p	CLIP-seq
MIRT2099278	hsa-miR-3622a-5p	CLIP-seq
MIRT1335748	hsa-miR-3692	CLIP-seq
MIRT2099279	hsa-miR-370	CLIP-seq
MIRT2099280	hsa-miR-371b-5p	CLIP-seq
MIRT1335749	hsa-miR-3921	CLIP-seq
MIRT2099281	hsa-miR-3942-3p	CLIP-seq
MIRT2099282	hsa-miR-4269	CLIP-seq
MIRT2099283	hsa-miR-4270	CLIP-seq
MIRT1335751	hsa-miR-4276	CLIP-seq
MIRT2099284	hsa-miR-4291	CLIP-seq
MIRT2099285	hsa-miR-4303	CLIP-seq
MIRT2099286	hsa-miR-4310	CLIP-seq
MIRT2099287	hsa-miR-4423-3p	CLIP-seq
MIRT2099288	hsa-miR-4441	CLIP-seq
MIRT2099289	hsa-miR-4468	CLIP-seq
MIRT2099290	hsa-miR-4477b	CLIP-seq
MIRT2099291	hsa-miR-4530	CLIP-seq
MIRT1335759	hsa-miR-4653-5p	CLIP-seq
MIRT1335760	hsa-miR-4659a-3p	CLIP-seq
MIRT1335761	hsa-miR-4659b-3p	CLIP-seq
MIRT2099292	hsa-miR-4690-5p	CLIP-seq
MIRT1335765	hsa-miR-4719	CLIP-seq
MIRT2099293	hsa-miR-4735-3p	CLIP-seq
MIRT2099294	hsa-miR-4753-3p	CLIP-seq
MIRT1335771	hsa-miR-513a-3p	CLIP-seq
MIRT2099295	hsa-miR-518a-5p	CLIP-seq
MIRT2099296	hsa-miR-520a-5p	CLIP-seq
MIRT2099297	hsa-miR-525-5p	CLIP-seq
MIRT2099298	hsa-miR-527	CLIP-seq
MIRT2099299	hsa-miR-543	CLIP-seq
MIRT2099300	hsa-miR-548b-3p	CLIP-seq
MIRT2099301	hsa-miR-634	CLIP-seq
MIRT2099302	hsa-miR-646	CLIP-seq
MIRT2099303	hsa-miR-759	CLIP-seq
MIRT2099304	hsa-miR-761	CLIP-seq
MIRT2099305	hsa-miR-802	CLIP-seq
MIRT2099306	hsa-miR-885-3p	CLIP-seq
MIRT2099307	hsa-miR-888	CLIP-seq
MIRT2099308	hsa-miR-922	CLIP-seq
MIRT2323994	hsa-miR-1208	CLIP-seq
MIRT2099264	hsa-miR-1226	CLIP-seq
MIRT2323995	hsa-miR-1227	CLIP-seq
MIRT2323996	hsa-miR-1273d	CLIP-seq
MIRT1335737	hsa-miR-132	CLIP-seq
MIRT2323997	hsa-miR-145	CLIP-seq
MIRT2323998	hsa-miR-146a	CLIP-seq
MIRT2323999	hsa-miR-146b-5p	CLIP-seq
MIRT2324000	hsa-miR-147	CLIP-seq
MIRT2324001	hsa-miR-1470	CLIP-seq
MIRT2099267	hsa-miR-18a	CLIP-seq
MIRT2099268	hsa-miR-18b	CLIP-seq
MIRT2324002	hsa-miR-1909	CLIP-seq
MIRT2324003	hsa-miR-197	CLIP-seq
MIRT1335739	hsa-miR-1972	CLIP-seq
MIRT2099269	hsa-miR-1976	CLIP-seq
MIRT1335742	hsa-miR-212	CLIP-seq
MIRT2099270	hsa-miR-214	CLIP-seq
MIRT2324004	hsa-miR-224	CLIP-seq
MIRT2099271	hsa-miR-28-3p	CLIP-seq
MIRT2099274	hsa-miR-3133	CLIP-seq
MIRT1335744	hsa-miR-3194-5p	CLIP-seq
MIRT2324005	hsa-miR-361-3p	CLIP-seq
MIRT2099277	hsa-miR-3619-5p	CLIP-seq
MIRT2099278	hsa-miR-3622a-5p	CLIP-seq
MIRT2324006	hsa-miR-3646	CLIP-seq
MIRT1335747	hsa-miR-3691-3p	CLIP-seq
MIRT2099279	hsa-miR-370	CLIP-seq
MIRT2324007	hsa-miR-3911	CLIP-seq
MIRT1335749	hsa-miR-3921	CLIP-seq
MIRT1335750	hsa-miR-3940-5p	CLIP-seq
MIRT2099282	hsa-miR-4269	CLIP-seq
MIRT2099284	hsa-miR-4291	CLIP-seq
MIRT2099285	hsa-miR-4303	CLIP-seq
MIRT2099287	hsa-miR-4423-3p	CLIP-seq
MIRT2324008	hsa-miR-4436b-5p	CLIP-seq
MIRT2099289	hsa-miR-4468	CLIP-seq
MIRT2099290	hsa-miR-4477b	CLIP-seq
MIRT2324009	hsa-miR-4480	CLIP-seq
MIRT1335756	hsa-miR-4507	CLIP-seq
MIRT2099291	hsa-miR-4530	CLIP-seq
MIRT1335757	hsa-miR-455-3p	CLIP-seq
MIRT2324010	hsa-miR-4649-3p	CLIP-seq
MIRT1335758	hsa-miR-4650-5p	CLIP-seq
MIRT1335759	hsa-miR-4653-5p	CLIP-seq
MIRT2324011	hsa-miR-4667-3p	CLIP-seq
MIRT1335762	hsa-miR-4677-3p	CLIP-seq
MIRT1335764	hsa-miR-4687-5p	CLIP-seq
MIRT2099292	hsa-miR-4690-5p	CLIP-seq
MIRT2324012	hsa-miR-4693-3p	CLIP-seq
MIRT2324013	hsa-miR-4704-5p	CLIP-seq
MIRT2324014	hsa-miR-4709-3p	CLIP-seq
MIRT2324015	hsa-miR-4727-5p	CLIP-seq
MIRT2099293	hsa-miR-4735-3p	CLIP-seq
MIRT2099294	hsa-miR-4753-3p	CLIP-seq
MIRT1335767	hsa-miR-4766-5p	CLIP-seq
MIRT2324016	hsa-miR-4769-3p	CLIP-seq
MIRT2324017	hsa-miR-4773	CLIP-seq
MIRT1335769	hsa-miR-488	CLIP-seq
MIRT2324018	hsa-miR-499-3p	CLIP-seq
MIRT2324019	hsa-miR-499a-3p	CLIP-seq
MIRT1335771	hsa-miR-513a-3p	CLIP-seq
MIRT2099295	hsa-miR-518a-5p	CLIP-seq
MIRT1335772	hsa-miR-520d-5p	CLIP-seq
MIRT1335773	hsa-miR-524-5p	CLIP-seq
MIRT2099298	hsa-miR-527	CLIP-seq
MIRT1335774	hsa-miR-548an	CLIP-seq
MIRT2099300	hsa-miR-548b-3p	CLIP-seq
MIRT2324020	hsa-miR-556-3p	CLIP-seq
MIRT2324021	hsa-miR-581	CLIP-seq
MIRT2324022	hsa-miR-589	CLIP-seq
MIRT2099301	hsa-miR-634	CLIP-seq
MIRT2324023	hsa-miR-642a	CLIP-seq
MIRT2324024	hsa-miR-644	CLIP-seq
MIRT2099302	hsa-miR-646	CLIP-seq
MIRT2324025	hsa-miR-718	CLIP-seq
MIRT2099304	hsa-miR-761	CLIP-seq
MIRT2099308	hsa-miR-922	CLIP-seq
MIRT2324026	hsa-miR-935	CLIP-seq
MIRT1335729	hsa-let-7a	CLIP-seq
MIRT1335730	hsa-let-7b	CLIP-seq
MIRT1335731	hsa-let-7c	CLIP-seq
MIRT1335732	hsa-let-7d	CLIP-seq
MIRT1335733	hsa-let-7e	CLIP-seq
MIRT1335734	hsa-let-7f	CLIP-seq
MIRT1335735	hsa-let-7g	CLIP-seq
MIRT1335736	hsa-let-7i	CLIP-seq
MIRT2619877	hsa-miR-122	CLIP-seq
MIRT2619878	hsa-miR-1260	CLIP-seq
MIRT2619879	hsa-miR-1260b	CLIP-seq
MIRT2323996	hsa-miR-1273d	CLIP-seq
MIRT2323998	hsa-miR-146a	CLIP-seq
MIRT2323999	hsa-miR-146b-5p	CLIP-seq
MIRT2324000	hsa-miR-147	CLIP-seq
MIRT2619880	hsa-miR-181a	CLIP-seq
MIRT2619881	hsa-miR-181b	CLIP-seq
MIRT2619882	hsa-miR-181c	CLIP-seq
MIRT2619883	hsa-miR-181d	CLIP-seq
MIRT2619884	hsa-miR-186	CLIP-seq
MIRT2619885	hsa-miR-188-3p	CLIP-seq
MIRT2324002	hsa-miR-1909	CLIP-seq
MIRT1335740	hsa-miR-202	CLIP-seq
MIRT2619886	hsa-miR-2116	CLIP-seq
MIRT2619887	hsa-miR-216b	CLIP-seq
MIRT2619888	hsa-miR-2277-3p	CLIP-seq
MIRT2619889	hsa-miR-27a	CLIP-seq
MIRT2619890	hsa-miR-27b	CLIP-seq
MIRT2619891	hsa-miR-3150a-3p	CLIP-seq
MIRT2619892	hsa-miR-3156-3p	CLIP-seq
MIRT1335748	hsa-miR-3692	CLIP-seq
MIRT2619893	hsa-miR-375	CLIP-seq
MIRT2619894	hsa-miR-376a	CLIP-seq
MIRT2619895	hsa-miR-376b	CLIP-seq
MIRT2619896	hsa-miR-4262	CLIP-seq
MIRT2619897	hsa-miR-4273	CLIP-seq
MIRT1335751	hsa-miR-4276	CLIP-seq
MIRT2619898	hsa-miR-4450	CLIP-seq
MIRT1335753	hsa-miR-4458	CLIP-seq
MIRT2619899	hsa-miR-4474-5p	CLIP-seq
MIRT2324009	hsa-miR-4480	CLIP-seq
MIRT1335755	hsa-miR-4500	CLIP-seq
MIRT2619900	hsa-miR-4534	CLIP-seq
MIRT1335760	hsa-miR-4659a-3p	CLIP-seq
MIRT1335761	hsa-miR-4659b-3p	CLIP-seq
MIRT2619901	hsa-miR-4668-5p	CLIP-seq
MIRT1335762	hsa-miR-4677-3p	CLIP-seq
MIRT2619902	hsa-miR-4677-5p	CLIP-seq
MIRT1335765	hsa-miR-4719	CLIP-seq
MIRT2324017	hsa-miR-4773	CLIP-seq
MIRT2619903	hsa-miR-4797-3p	CLIP-seq
MIRT2619904	hsa-miR-491-5p	CLIP-seq
MIRT2619905	hsa-miR-495	CLIP-seq
MIRT1335771	hsa-miR-513a-3p	CLIP-seq
MIRT2619906	hsa-miR-513a-5p	CLIP-seq
MIRT2619907	hsa-miR-578	CLIP-seq
MIRT2324021	hsa-miR-581	CLIP-seq
MIRT2324022	hsa-miR-589	CLIP-seq
MIRT2619908	hsa-miR-605	CLIP-seq
MIRT2619909	hsa-miR-939	CLIP-seq
MIRT1335777	hsa-miR-98	CLIP-seq
MIRT2619877	hsa-miR-122	CLIP-seq
MIRT2619878	hsa-miR-1260	CLIP-seq
MIRT2619879	hsa-miR-1260b	CLIP-seq
MIRT2323996	hsa-miR-1273d	CLIP-seq
MIRT2323998	hsa-miR-146a	CLIP-seq
MIRT2323999	hsa-miR-146b-5p	CLIP-seq
MIRT2619880	hsa-miR-181a	CLIP-seq
MIRT2619881	hsa-miR-181b	CLIP-seq
MIRT2619882	hsa-miR-181c	CLIP-seq
MIRT2619883	hsa-miR-181d	CLIP-seq
MIRT2619884	hsa-miR-186	CLIP-seq
MIRT2619885	hsa-miR-188-3p	CLIP-seq
MIRT2324002	hsa-miR-1909	CLIP-seq
MIRT2619887	hsa-miR-216b	CLIP-seq
MIRT2619888	hsa-miR-2277-3p	CLIP-seq
MIRT2619889	hsa-miR-27a	CLIP-seq
MIRT2619890	hsa-miR-27b	CLIP-seq
MIRT2619891	hsa-miR-3150a-3p	CLIP-seq
MIRT2619892	hsa-miR-3156-3p	CLIP-seq
MIRT1335748	hsa-miR-3692	CLIP-seq
MIRT2619894	hsa-miR-376a	CLIP-seq
MIRT2619895	hsa-miR-376b	CLIP-seq
MIRT2619896	hsa-miR-4262	CLIP-seq
MIRT1335751	hsa-miR-4276	CLIP-seq
MIRT2619898	hsa-miR-4450	CLIP-seq
MIRT2619899	hsa-miR-4474-5p	CLIP-seq
MIRT2324009	hsa-miR-4480	CLIP-seq
MIRT2619900	hsa-miR-4534	CLIP-seq
MIRT1335760	hsa-miR-4659a-3p	CLIP-seq
MIRT1335761	hsa-miR-4659b-3p	CLIP-seq
MIRT2619901	hsa-miR-4668-5p	CLIP-seq
MIRT1335762	hsa-miR-4677-3p	CLIP-seq
MIRT1335765	hsa-miR-4719	CLIP-seq
MIRT2324017	hsa-miR-4773	CLIP-seq
MIRT2619903	hsa-miR-4797-3p	CLIP-seq
MIRT2619904	hsa-miR-491-5p	CLIP-seq
MIRT2619905	hsa-miR-495	CLIP-seq
MIRT1335771	hsa-miR-513a-3p	CLIP-seq
MIRT2619906	hsa-miR-513a-5p	CLIP-seq
MIRT2324022	hsa-miR-589	CLIP-seq
MIRT2619908	hsa-miR-605	CLIP-seq
MIRT2619909	hsa-miR-939	CLIP-seq

Show/Hide all(45)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	11896061, 15296745, 17099700, 20098747, 21965678, 25416956, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005643	Component	Nuclear pore	IDA	12192048
GO:0005643	Component	Nuclear pore	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006508	Process	Proteolysis	IEA
GO:0007507	Process	Heart development	IEA
GO:0008233	Function	Peptidase activity	IEA
GO:0008234	Function	Cysteine-type peptidase activity	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016604	Component	Nuclear body	IEA
GO:0016605	Component	PML body	IEA
GO:0016605	Component	PML body	ISS
GO:0016787	Function	Hydrolase activity	IEA
GO:0016925	Process	Protein sumoylation	IEA
GO:0016925	Process	Protein sumoylation	TAS
GO:0016926	Process	Protein desumoylation	IBA
GO:0016926	Process	Protein desumoylation	IDA	20194620
GO:0016926	Process	Protein desumoylation	IEA
GO:0016926	Process	Protein desumoylation	IMP	21965678, 22028379
GO:0016929	Function	DeSUMOylase activity	IBA
GO:0016929	Function	DeSUMOylase activity	IEA
GO:0030111	Process	Regulation of Wnt signaling pathway	NAS	11896061
GO:0031397	Process	Negative regulation of protein ubiquitination	IDA	22028379
GO:0031398	Process	Positive regulation of protein ubiquitination	IMP	22028379
GO:0031648	Process	Protein destabilization	IMP	22028379
GO:0031965	Component	Nuclear membrane	IEA
GO:0032875	Process	Regulation of DNA endoreduplication	IEA
GO:0045444	Process	Fat cell differentiation	IEA
GO:0045444	Process	Fat cell differentiation	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0051028	Process	MRNA transport	IEA
GO:0060255	Process	Regulation of macromolecule metabolic process	IEA
GO:0060707	Process	Trophoblast giant cell differentiation	IEA
GO:0060711	Process	Labyrinthine layer development	IEA
GO:0070139	Function	SUMO-specific endopeptidase activity	EXP	16608850, 17591783
GO:0070139	Function	SUMO-specific endopeptidase activity	IDA	11896061
GO:0070139	Function	SUMO-specific endopeptidase activity	IEA
GO:0080090	Process	Regulation of primary metabolic process	IEA
GO:2000045	Process	Regulation of G1/S transition of mitotic cell cycle	IEA

MIM	HGNC	e!Ensembl
608261	23116	ENSG00000163904

Protein

UniProt ID

Q9HC62

Protein name

Sentrin-specific protease 2 (EC 3.4.22.-) (Axam2) (SMT3-specific isopeptidase 2) (Smt3ip2) (Sentrin/SUMO-specific protease SENP2)

Protein function

Protease that catalyzes two essential functions in the SUMO pathway (PubMed:11896061, PubMed:12192048, PubMed:15296745, PubMed:20194620, PubMed:21965678). The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the s

PDB

1TGZ , 1TH0 , 2IO0 , 2IO1 , 2IO2 , 2IO3 , 3ZO5 , 5AEK

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02902	Peptidase_C48	409 → 588	Ulp1 protease family, C-terminal catalytic domain	Domain

Sequence

MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVK
NSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLG
NKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKP
QEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYH
SSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTE
TMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDR
RTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYM
NLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWS
LVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIP
QQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL

Sequence length

589

Interactions

View interactions

	KEGG		Reactome
	Nucleocytoplasmic transport Wnt signaling pathway		SUMO is proteolytically processed

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes, Type 2 diabetes (adjusted for BMI)	N/A	N/A	GWAS
Gout	Gout	N/A	N/A	GWAS
Seborrheic dermatitis	Seborrheic dermatitis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (16)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	23874428
Breast Neoplasms	Associate	24422630, 27178176, 29955155, 30732133
Carcinogenesis	Associate	29955155
Carcinoma Hepatocellular	Associate	23098437, 24969559
Carcinoma Squamous Cell	Associate	24004673
Chromosome Aberrations	Associate	21595939
Hypoxia	Associate	30612578
Leukemia Lymphocytic Chronic B Cell	Inhibit	30431078
Lymphatic Metastasis	Associate	30732133
Multiple Myeloma	Associate	31964975
Neoplasm Metastasis	Associate	23874428, 26369384, 27178176
Neoplasm Metastasis	Inhibit	24008762
Neoplasms	Associate	23098437, 29955155
Neoplasms	Inhibit	24969559, 29060933, 30431078
Stomach Neoplasms	Associate	29060933
Urinary Bladder Neoplasms	Inhibit	24008762, 26369384

SENP2 (SUMO specific peptidase 2)