RAP1B (RAP1B, member of RAS oncogene family)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 5908 |
| Gene name | RAP1B, member of RAS oncogene family |
| Gene symbol | RAP1B |
| Synonyms (NCBI Gene) |
K-REVRAL1BTHC11
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| Chromosome | 12 |
| Chromosome location | 12q15 |
| Summary | This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been |
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miRNA
miRNA information provided by mirtarbase database.
720
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P61224 | ||||||||||
| Protein name | Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B) | ||||||||||
| Protein function | GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of | ||||||||||
| PDB | 3BRW , 3CF6 , 4DXA , 4HDO , 4HDQ , 4M8N , 4MGI , 4MGK , 4MGY , 4MGZ , 4MH0 , 5KHO , 6AXF , 6BA6 , 6KYK , 6OQ3 , 6OQ4 , 6UZK , 7C7I , 7C7J , 8SU8 , 8T09 , 8T7V | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 184 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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