Gene Gene information from NCBI Gene database.
Entrez ID 5874
Gene name RAB27B, member RAS oncogene family
Gene symbol RAB27B
Synonyms (NCBI Gene)
C25KG
Chromosome 18
Chromosome location 18q21.2
Summary Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010]
miRNA miRNA information provided by mirtarbase database.
561
miRTarBase ID miRNA Experiments Reference
MIRT005197 hsa-miR-30a-5p pSILAC 18668040
MIRT001512 hsa-miR-155-5p pSILAC 18668040
MIRT001512 hsa-miR-155-5p Proteomics;Other 18668040
MIRT023764 hsa-miR-1-3p Proteomics 18668040
MIRT005197 hsa-miR-30a-5p Proteomics;Other 18668040
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
47
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0003924 Function GTPase activity IBA
GO:0003924 Function GTPase activity IEA
GO:0003924 Function GTPase activity ISS
GO:0003925 Function G protein activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603869 9767 ENSG00000041353
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O00194
Protein name Ras-related protein Rab-27B (EC 3.6.5.2) (C25KG)
Protein function Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and sec
PDB 2F7S
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 11 183 Ras family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed primarily in testis.
Sequence
Sequence length 218
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Pancreatic secretion   Platelet degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs