Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	58516
Gene name Gene Name - the full gene name approved by the HGNC.	SIN3-HDAC complex associated factor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SINHCAF
Synonyms (NCBI Gene) Gene synonyms aliases	C12orf14, FAM60A, L4, TERA
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12p11.21

Show/Hide all(82)

miRTarBase ID	miRNA	Experiments	Reference
MIRT703663	hsa-miR-495-5p	HITS-CLIP	23313552
MIRT703662	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT703661	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT703660	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT703659	hsa-miR-940	HITS-CLIP	23313552
MIRT703658	hsa-miR-3929	HITS-CLIP	23313552
MIRT703657	hsa-miR-4419b	HITS-CLIP	23313552
MIRT703656	hsa-miR-4478	HITS-CLIP	23313552
MIRT703655	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT703654	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT703653	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT703652	hsa-miR-1247-3p	HITS-CLIP	23313552
MIRT703651	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT703650	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT703649	hsa-miR-1827	HITS-CLIP	23313552
MIRT703648	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT703647	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT703646	hsa-miR-139-3p	HITS-CLIP	23313552
MIRT703645	hsa-miR-455-3p	HITS-CLIP	23313552
MIRT703644	hsa-miR-6516-5p	HITS-CLIP	23313552
MIRT703643	hsa-miR-665	HITS-CLIP	23313552
MIRT559915	hsa-miR-583	PAR-CLIP	20371350
MIRT559912	hsa-miR-1178-5p	PAR-CLIP	20371350
MIRT567617	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT559910	hsa-miR-4328	PAR-CLIP	20371350
MIRT567616	hsa-miR-371b-5p	PAR-CLIP	20371350
MIRT567615	hsa-miR-373-5p	PAR-CLIP	20371350
MIRT567614	hsa-miR-616-5p	PAR-CLIP	20371350
MIRT567613	hsa-miR-371a-5p	PAR-CLIP	20371350
MIRT567612	hsa-miR-372-5p	PAR-CLIP	20371350
MIRT559911	hsa-miR-223-3p	PAR-CLIP	20371350
MIRT559909	hsa-miR-4668-5p	PAR-CLIP	20371350
MIRT559907	hsa-miR-5087	PAR-CLIP	20371350
MIRT559915	hsa-miR-583	PAR-CLIP	20371350
MIRT559914	hsa-miR-208a-5p	PAR-CLIP	20371350
MIRT559913	hsa-miR-208b-5p	PAR-CLIP	20371350
MIRT567617	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT559910	hsa-miR-4328	PAR-CLIP	20371350
MIRT567616	hsa-miR-371b-5p	PAR-CLIP	20371350
MIRT567615	hsa-miR-373-5p	PAR-CLIP	20371350
MIRT567614	hsa-miR-616-5p	PAR-CLIP	20371350
MIRT567613	hsa-miR-371a-5p	PAR-CLIP	20371350
MIRT567612	hsa-miR-372-5p	PAR-CLIP	20371350
MIRT559909	hsa-miR-4668-5p	PAR-CLIP	20371350
MIRT559911	hsa-miR-223-3p	PAR-CLIP	20371350
MIRT559908	hsa-miR-3674	PAR-CLIP	20371350
MIRT559907	hsa-miR-5087	PAR-CLIP	20371350
MIRT559915	hsa-miR-583	PAR-CLIP	20371350
MIRT559914	hsa-miR-208a-5p	PAR-CLIP	20371350
MIRT559913	hsa-miR-208b-5p	PAR-CLIP	20371350
MIRT559912	hsa-miR-1178-5p	PAR-CLIP	20371350
MIRT559910	hsa-miR-4328	PAR-CLIP	20371350
MIRT559911	hsa-miR-223-3p	PAR-CLIP	20371350
MIRT559908	hsa-miR-3674	PAR-CLIP	20371350
MIRT559909	hsa-miR-4668-5p	PAR-CLIP	20371350
MIRT559907	hsa-miR-5087	PAR-CLIP	20371350
MIRT507323	hsa-miR-548n	PAR-CLIP	21572407
MIRT507322	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT507321	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT507320	hsa-miR-561-3p	PAR-CLIP	21572407
MIRT507319	hsa-miR-628-3p	PAR-CLIP	21572407
MIRT507317	hsa-miR-2052	PAR-CLIP	21572407
MIRT507323	hsa-miR-548n	PAR-CLIP	22012620
MIRT507322	hsa-miR-548az-5p	PAR-CLIP	22012620
MIRT507321	hsa-miR-548t-5p	PAR-CLIP	22012620
MIRT507320	hsa-miR-561-3p	PAR-CLIP	22012620
MIRT507319	hsa-miR-628-3p	PAR-CLIP	22012620
MIRT507317	hsa-miR-2052	PAR-CLIP	22012620
MIRT507323	hsa-miR-548n	PAR-CLIP	23446348
MIRT507322	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT507321	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT507320	hsa-miR-561-3p	PAR-CLIP	23446348
MIRT507319	hsa-miR-628-3p	PAR-CLIP	23446348
MIRT507317	hsa-miR-2052	PAR-CLIP	23446348
MIRT477012	hsa-miR-5692a	PAR-CLIP	23592263
MIRT477011	hsa-miR-4318	PAR-CLIP	23592263
MIRT477010	hsa-miR-325	PAR-CLIP	23592263
MIRT477009	hsa-miR-601	PAR-CLIP	23592263
MIRT477008	hsa-miR-380-5p	PAR-CLIP	23592263
MIRT477007	hsa-miR-563	PAR-CLIP	23592263
MIRT477006	hsa-miR-203a-5p	PAR-CLIP	23592263
MIRT477005	hsa-miR-1273g-5p	PAR-CLIP	23592263

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	23752268, 26496610, 28514442, 32296183
GO:0008284	Process	Positive regulation of cell population proliferation	ISS
GO:0016580	Component	Sin3 complex	IBA	21873635
GO:0016580	Component	Sin3 complex	IDA	22984288
GO:0030336	Process	Negative regulation of cell migration	IBA	21873635
GO:0030336	Process	Negative regulation of cell migration	IMP	22984288
GO:0045596	Process	Negative regulation of cell differentiation	ISS

MIM	HGNC	e!Ensembl
615027	30702	ENSG00000139146

Protein

UniProt ID

Q9NP50

Protein name

SIN3-HDAC complex-associated factor (Protein FAM60A) (Tera protein homolog)

Protein function

Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (PubMed:22865885, PubMed:22984288). Core component of a SIN3A complex (composed of a

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15396	FAM60A	2 → 198	Protein Family FAM60A	Family

Sequence

MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLV
KRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKVKTLSGNRIKSNQISKLQKEFKRHNS
DAHSTTSSASPAQSPCYSNQSDDGSDTEMASGSNRTPVFSFLDLTYWKRQKICCGIIYKG
RFGEVLIDTHLFKPCCSNKKAAAEKPEEQGPEPLPISTQEW

Sequence length

221

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Diabetes mellitus	Diabetes Mellitus, Non-Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237 View all (293 more)	26818947, 30718926

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Diabetes	Diabetes	GWAS
Coronary artery disease	Coronary artery disease	GWAS

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining
Esophageal Neoplasms	Associate	28169357
Osteosarcoma	Stimulate	37439040

SINHCAF (SIN3-HDAC complex associated factor)