Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	58506
Gene name Gene Name - the full gene name approved by the HGNC.	SR-related CTD associated factor 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SCAF1
Synonyms (NCBI Gene) Gene synonyms aliases	SRA1
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.33

Show/Hide all(41)

miRTarBase ID	miRNA	Experiments	Reference
MIRT026982	hsa-miR-103a-3p	Sequencing	20371350
MIRT028412	hsa-miR-30a-5p	Proteomics	18668040
MIRT044596	hsa-miR-320a	CLASH	23622248
MIRT040703	hsa-miR-92b-3p	CLASH	23622248
MIRT1327708	hsa-miR-1321	CLIP-seq
MIRT1327709	hsa-miR-2110	CLIP-seq
MIRT1327710	hsa-miR-3144-5p	CLIP-seq
MIRT1327711	hsa-miR-3150a-3p	CLIP-seq
MIRT1327712	hsa-miR-3175	CLIP-seq
MIRT1327713	hsa-miR-3184	CLIP-seq
MIRT1327714	hsa-miR-3191	CLIP-seq
MIRT1327715	hsa-miR-423-5p	CLIP-seq
MIRT1327716	hsa-miR-4438	CLIP-seq
MIRT1327717	hsa-miR-4652-5p	CLIP-seq
MIRT1327718	hsa-miR-4667-5p	CLIP-seq
MIRT1327719	hsa-miR-4688	CLIP-seq
MIRT1327720	hsa-miR-4700-5p	CLIP-seq
MIRT1327721	hsa-miR-4728-5p	CLIP-seq
MIRT1327722	hsa-miR-4739	CLIP-seq
MIRT1327723	hsa-miR-4756-5p	CLIP-seq
MIRT1327724	hsa-miR-939	CLIP-seq
MIRT2097289	hsa-miR-3156-3p	CLIP-seq
MIRT2097290	hsa-miR-4301	CLIP-seq
MIRT1327708	hsa-miR-1321	CLIP-seq
MIRT2321618	hsa-miR-198	CLIP-seq
MIRT1327709	hsa-miR-2110	CLIP-seq
MIRT1327711	hsa-miR-3150a-3p	CLIP-seq
MIRT2321619	hsa-miR-3154	CLIP-seq
MIRT1327712	hsa-miR-3175	CLIP-seq
MIRT1327713	hsa-miR-3184	CLIP-seq
MIRT1327715	hsa-miR-423-5p	CLIP-seq
MIRT1327719	hsa-miR-4688	CLIP-seq
MIRT2321620	hsa-miR-4710	CLIP-seq
MIRT1327721	hsa-miR-4728-5p	CLIP-seq
MIRT1327722	hsa-miR-4739	CLIP-seq
MIRT1327723	hsa-miR-4756-5p	CLIP-seq
MIRT2321621	hsa-miR-520a-5p	CLIP-seq
MIRT2321622	hsa-miR-525-5p	CLIP-seq
MIRT2321623	hsa-miR-583	CLIP-seq
MIRT2321624	hsa-miR-607	CLIP-seq
MIRT1327724	hsa-miR-939	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0006366	Process	Transcription by RNA polymerase II	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0019904	Function	Protein domain specific binding	IEA
GO:0099122	Function	RNA polymerase II C-terminal domain binding	IBA	21873635
GO:0099122	Function	RNA polymerase II C-terminal domain binding	IPI	15992770

MIM	HGNC	e!Ensembl
617264	30403	ENSG00000126461

Protein

UniProt ID

Q9H7N4

Protein name

Splicing factor, arginine/serine-rich 19 (SR-related C-terminal domain-associated factor 1) (SR-related and CTD-associated factor 1) (SR-related-CTD-associated factor) (SCAF) (Serine arginine-rich pre-mRNA splicing factor SR-A1) (SR-A1)

Protein function

May function in pre-mRNA splicing.

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colo

Sequence

MEEEDESRGKTEESGEDRGDGPPDRDPTLSPSAFILRAIQQAVGSSLQGDLPNDKDGSRC
HGLRWRRCRSPRSEPRSQESGGTDTATVLDMATDSFLAGLVSVLDPPDTWVPSRLDLRPG
ESEDMLELVAEVRIGDRDPIPLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTG
DGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSP
PPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISET
LAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAE
ACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPT
PAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGL
DLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQ
PAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRS
RSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSE
KAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSP
APASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDR
DRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVL
IREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKT
KVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAE
ETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGG
AEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQ
LPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRKP
PSSLGMTPAPVPTSLGLPPGPSSYLLPGSLPLGGCGSTPPTPTGLAATSDKREGSSSSEG
RGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEINP
VKVSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLPPL

Sequence length

1312

Interactions

View interactions

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Basal cell neoplasm	Basal Cell Neoplasm, Basal Cell Cancer	rs587776578, rs587776579, rs2117956624, rs2118419579, rs2118365442, rs2118041703, rs2136689212, rs2118336503, rs1587692888, rs267606984, rs878853849, rs1554695110, rs1064793921, rs1588605348, rs1588568813	31174203
Carcinoma	Basal cell carcinoma	rs121912654, rs555607708, rs786202962, rs1564055259	31174203
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	29483656

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Dyslexia	Dyslexia			GWAS

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Autistic Disorder	Associate	35982159
Cognition Disorders	Associate	35982159
Prostate cancer familial	Associate	31511525

SCAF1 (SR-related CTD associated factor 1)