Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
58505
Gene name Gene Name - the full gene name approved by the HGNC.
Oligosaccharyltransferase complex non-catalytic subunit
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
OSTC
Synonyms (NCBI Gene) Gene synonyms aliases
DC2
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q25
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT043072 hsa-miR-324-5p CLASH 23622248
MIRT440062 hsa-miR-377-3p HITS-CLIP 24374217
MIRT440062 hsa-miR-377-3p HITS-CLIP 24374217
MIRT1206999 hsa-miR-1290 CLIP-seq
MIRT1207000 hsa-miR-1298 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004579 Function Dolichyl-diphosphooligosaccharide-protein glycotransferase activity IC 15835887
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IDA 21768116
GO:0005789 Component Endoplasmic reticulum membrane NAS 31831667
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
619023 24448 ENSG00000198856
Protein
UniProt ID Q9NRP0
Protein name Oligosaccharyltransferase complex subunit OSTC (Hydrophobic protein HSF-28)
Protein function Subunit of STT3A-containing oligosaccharyl transferase (OST-A) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an
PDB 6S7O , 8B6L , 8PN9
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04756 OST3_OST6 9 148 OST3 / OST6 family, transporter family Family
Sequence
Sequence length 149
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  N-Glycan biosynthesis
Various types of N-glycan biosynthesis
Protein processing in endoplasmic reticulum
 
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Glioblastoma Glioblastoma N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Coronary Artery Disease Associate 32710445
Drug Hypersensitivity Associate 32431702
Inflammation Associate 32431702
Pulmonary Disease Chronic Obstructive Associate 37466093