OSTC (oligosaccharyltransferase complex non-catalytic subunit)

Gene

• Entrez ID: 58505
• Gene name: Oligosaccharyltransferase complex non-catalytic subunit
• Gene symbol: OSTC
• Synonyms (NCBI Gene): DC2
• Chromosome: 4
• Chromosome location: 4q25

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT043072	hsa-miR-324-5p	CLASH	23622248
MIRT440062	hsa-miR-377-3p	HITS-CLIP	24374217
MIRT440062	hsa-miR-377-3p	HITS-CLIP	24374217
MIRT1206999	hsa-miR-1290	CLIP-seq
MIRT1207000	hsa-miR-1298	CLIP-seq
MIRT1207001	hsa-miR-1299	CLIP-seq
MIRT1207002	hsa-miR-198	CLIP-seq
MIRT1207003	hsa-miR-2053	CLIP-seq
MIRT1207004	hsa-miR-214	CLIP-seq
MIRT1207005	hsa-miR-296-3p	CLIP-seq
MIRT1207006	hsa-miR-29a	CLIP-seq
MIRT1207007	hsa-miR-29b	CLIP-seq
MIRT1207008	hsa-miR-29c	CLIP-seq
MIRT1207009	hsa-miR-3145-3p	CLIP-seq
MIRT1207010	hsa-miR-3148	CLIP-seq
MIRT1207011	hsa-miR-3167	CLIP-seq
MIRT1207012	hsa-miR-320a	CLIP-seq
MIRT1207013	hsa-miR-320b	CLIP-seq
MIRT1207014	hsa-miR-320c	CLIP-seq
MIRT1207015	hsa-miR-320d	CLIP-seq
MIRT1207016	hsa-miR-330-3p	CLIP-seq
MIRT1207017	hsa-miR-34b	CLIP-seq
MIRT1207018	hsa-miR-3613-3p	CLIP-seq
MIRT1207019	hsa-miR-3619-5p	CLIP-seq
MIRT1207020	hsa-miR-3674	CLIP-seq
MIRT1207021	hsa-miR-3688-3p	CLIP-seq
MIRT1207022	hsa-miR-3689a-5p	CLIP-seq
MIRT1207023	hsa-miR-3689b	CLIP-seq
MIRT1207024	hsa-miR-3689e	CLIP-seq
MIRT1207025	hsa-miR-3689f	CLIP-seq
MIRT1207026	hsa-miR-3692	CLIP-seq
MIRT1207027	hsa-miR-3908	CLIP-seq
MIRT1207028	hsa-miR-3935	CLIP-seq
MIRT1207029	hsa-miR-3942-5p	CLIP-seq
MIRT1207030	hsa-miR-3977	CLIP-seq
MIRT1207031	hsa-miR-4252	CLIP-seq
MIRT1207032	hsa-miR-4261	CLIP-seq
MIRT1207033	hsa-miR-4328	CLIP-seq
MIRT1207034	hsa-miR-4429	CLIP-seq
MIRT1207035	hsa-miR-4484	CLIP-seq
MIRT1207036	hsa-miR-4496	CLIP-seq
MIRT1207037	hsa-miR-4530	CLIP-seq
MIRT1207038	hsa-miR-4677-3p	CLIP-seq
MIRT1207039	hsa-miR-4679	CLIP-seq
MIRT1207040	hsa-miR-4703-5p	CLIP-seq
MIRT1207041	hsa-miR-4717-5p	CLIP-seq
MIRT1207042	hsa-miR-4766-3p	CLIP-seq
MIRT1207043	hsa-miR-4775	CLIP-seq
MIRT1207044	hsa-miR-4778-5p	CLIP-seq
MIRT1207045	hsa-miR-4782-5p	CLIP-seq
MIRT1207046	hsa-miR-4788	CLIP-seq
MIRT1207047	hsa-miR-515-5p	CLIP-seq
MIRT1207048	hsa-miR-516b	CLIP-seq
MIRT1207049	hsa-miR-520a-5p	CLIP-seq
MIRT1207050	hsa-miR-525-5p	CLIP-seq
MIRT1207051	hsa-miR-548an	CLIP-seq
MIRT1207052	hsa-miR-569	CLIP-seq
MIRT1207053	hsa-miR-603	CLIP-seq
MIRT1207054	hsa-miR-656	CLIP-seq
MIRT1207055	hsa-miR-761	CLIP-seq
MIRT1207056	hsa-miR-767-5p	CLIP-seq
MIRT1207057	hsa-miR-873	CLIP-seq
MIRT1207058	hsa-miR-876-5p	CLIP-seq
MIRT1207009	hsa-miR-3145-3p	CLIP-seq
MIRT1207020	hsa-miR-3674	CLIP-seq
MIRT1207028	hsa-miR-3935	CLIP-seq
MIRT1207054	hsa-miR-656	CLIP-seq
MIRT2059469	hsa-miR-1263	CLIP-seq
MIRT2059470	hsa-miR-1279	CLIP-seq
MIRT1207000	hsa-miR-1298	CLIP-seq
MIRT1207002	hsa-miR-198	CLIP-seq
MIRT2059471	hsa-miR-28-3p	CLIP-seq
MIRT1207006	hsa-miR-29a	CLIP-seq
MIRT1207007	hsa-miR-29b	CLIP-seq
MIRT1207008	hsa-miR-29c	CLIP-seq
MIRT2059472	hsa-miR-3125	CLIP-seq
MIRT1207009	hsa-miR-3145-3p	CLIP-seq
MIRT2059473	hsa-miR-3200-5p	CLIP-seq
MIRT1207012	hsa-miR-320a	CLIP-seq
MIRT1207013	hsa-miR-320b	CLIP-seq
MIRT1207014	hsa-miR-320c	CLIP-seq
MIRT1207015	hsa-miR-320d	CLIP-seq
MIRT1207026	hsa-miR-3692	CLIP-seq
MIRT2059474	hsa-miR-377	CLIP-seq
MIRT2059475	hsa-miR-3916	CLIP-seq
MIRT1207032	hsa-miR-4261	CLIP-seq
MIRT1207033	hsa-miR-4328	CLIP-seq
MIRT1207034	hsa-miR-4429	CLIP-seq
MIRT1207036	hsa-miR-4496	CLIP-seq
MIRT2059476	hsa-miR-4766-5p	CLIP-seq
MIRT1207046	hsa-miR-4788	CLIP-seq
MIRT2059477	hsa-miR-509-3p	CLIP-seq
MIRT2059478	hsa-miR-5096	CLIP-seq
MIRT2059479	hsa-miR-516a-3p	CLIP-seq
MIRT1207049	hsa-miR-520a-5p	CLIP-seq
MIRT1207050	hsa-miR-525-5p	CLIP-seq
MIRT2059480	hsa-miR-548a-3p	CLIP-seq
MIRT2059481	hsa-miR-548e	CLIP-seq
MIRT2059482	hsa-miR-548f	CLIP-seq
MIRT2059483	hsa-miR-554	CLIP-seq
MIRT2059484	hsa-miR-593	CLIP-seq
MIRT1207056	hsa-miR-767-5p	CLIP-seq
MIRT1207057	hsa-miR-873	CLIP-seq
MIRT2059485	hsa-miR-877	CLIP-seq
MIRT2059469	hsa-miR-1263	CLIP-seq
MIRT2059470	hsa-miR-1279	CLIP-seq
MIRT1206999	hsa-miR-1290	CLIP-seq
MIRT1207000	hsa-miR-1298	CLIP-seq
MIRT1207001	hsa-miR-1299	CLIP-seq
MIRT1207002	hsa-miR-198	CLIP-seq
MIRT1207006	hsa-miR-29a	CLIP-seq
MIRT1207007	hsa-miR-29b	CLIP-seq
MIRT1207008	hsa-miR-29c	CLIP-seq
MIRT2059472	hsa-miR-3125	CLIP-seq
MIRT1207009	hsa-miR-3145-3p	CLIP-seq
MIRT1207011	hsa-miR-3167	CLIP-seq
MIRT1207012	hsa-miR-320a	CLIP-seq
MIRT1207013	hsa-miR-320b	CLIP-seq
MIRT1207014	hsa-miR-320c	CLIP-seq
MIRT1207015	hsa-miR-320d	CLIP-seq
MIRT1207016	hsa-miR-330-3p	CLIP-seq
MIRT1207017	hsa-miR-34b	CLIP-seq
MIRT1207020	hsa-miR-3674	CLIP-seq
MIRT1207021	hsa-miR-3688-3p	CLIP-seq
MIRT1207026	hsa-miR-3692	CLIP-seq
MIRT2059474	hsa-miR-377	CLIP-seq
MIRT2059475	hsa-miR-3916	CLIP-seq
MIRT1207028	hsa-miR-3935	CLIP-seq
MIRT1207030	hsa-miR-3977	CLIP-seq
MIRT1207031	hsa-miR-4252	CLIP-seq
MIRT1207034	hsa-miR-4429	CLIP-seq
MIRT1207035	hsa-miR-4484	CLIP-seq
MIRT2287914	hsa-miR-4659a-3p	CLIP-seq
MIRT2287915	hsa-miR-4659b-3p	CLIP-seq
MIRT2287916	hsa-miR-4712-5p	CLIP-seq
MIRT1207045	hsa-miR-4782-5p	CLIP-seq
MIRT1207046	hsa-miR-4788	CLIP-seq
MIRT2059477	hsa-miR-509-3p	CLIP-seq
MIRT2287917	hsa-miR-513c	CLIP-seq
MIRT2287918	hsa-miR-514b-5p	CLIP-seq
MIRT1207048	hsa-miR-516b	CLIP-seq
MIRT1207049	hsa-miR-520a-5p	CLIP-seq
MIRT1207050	hsa-miR-525-5p	CLIP-seq
MIRT2059480	hsa-miR-548a-3p	CLIP-seq
MIRT1207051	hsa-miR-548an	CLIP-seq
MIRT2059481	hsa-miR-548e	CLIP-seq
MIRT2059482	hsa-miR-548f	CLIP-seq
MIRT1207053	hsa-miR-603	CLIP-seq
MIRT1207054	hsa-miR-656	CLIP-seq
MIRT1207056	hsa-miR-767-5p	CLIP-seq
MIRT2287919	hsa-miR-770-5p	CLIP-seq
MIRT1207058	hsa-miR-876-5p	CLIP-seq
MIRT2059485	hsa-miR-877	CLIP-seq
MIRT2287920	hsa-miR-942	CLIP-seq
MIRT1207006	hsa-miR-29a	CLIP-seq
MIRT1207007	hsa-miR-29b	CLIP-seq
MIRT1207008	hsa-miR-29c	CLIP-seq
MIRT1207009	hsa-miR-3145-3p	CLIP-seq
MIRT1207012	hsa-miR-320a	CLIP-seq
MIRT1207013	hsa-miR-320b	CLIP-seq
MIRT1207014	hsa-miR-320c	CLIP-seq
MIRT1207015	hsa-miR-320d	CLIP-seq
MIRT1207016	hsa-miR-330-3p	CLIP-seq
MIRT1207020	hsa-miR-3674	CLIP-seq
MIRT1207028	hsa-miR-3935	CLIP-seq
MIRT1207034	hsa-miR-4429	CLIP-seq
MIRT1207035	hsa-miR-4484	CLIP-seq
MIRT1207051	hsa-miR-548an	CLIP-seq
MIRT1207053	hsa-miR-603	CLIP-seq
MIRT1207054	hsa-miR-656	CLIP-seq
MIRT1207056	hsa-miR-767-5p	CLIP-seq
MIRT1207002	hsa-miR-198	CLIP-seq
MIRT1207006	hsa-miR-29a	CLIP-seq
MIRT1207007	hsa-miR-29b	CLIP-seq
MIRT1207008	hsa-miR-29c	CLIP-seq
MIRT2059473	hsa-miR-3200-5p	CLIP-seq
MIRT1207012	hsa-miR-320a	CLIP-seq
MIRT1207013	hsa-miR-320b	CLIP-seq
MIRT1207014	hsa-miR-320c	CLIP-seq
MIRT1207015	hsa-miR-320d	CLIP-seq
MIRT1207016	hsa-miR-330-3p	CLIP-seq
MIRT2059474	hsa-miR-377	CLIP-seq
MIRT1207030	hsa-miR-3977	CLIP-seq
MIRT1207032	hsa-miR-4261	CLIP-seq
MIRT1207033	hsa-miR-4328	CLIP-seq
MIRT1207034	hsa-miR-4429	CLIP-seq
MIRT1207035	hsa-miR-4484	CLIP-seq
MIRT1207036	hsa-miR-4496	CLIP-seq
MIRT2059476	hsa-miR-4766-5p	CLIP-seq
MIRT1207046	hsa-miR-4788	CLIP-seq
MIRT1207049	hsa-miR-520a-5p	CLIP-seq
MIRT1207050	hsa-miR-525-5p	CLIP-seq
MIRT1207051	hsa-miR-548an	CLIP-seq
MIRT1207053	hsa-miR-603	CLIP-seq
MIRT1207056	hsa-miR-767-5p	CLIP-seq
MIRT1207057	hsa-miR-873	CLIP-seq
MIRT2586081	hsa-miR-124	CLIP-seq
MIRT1206999	hsa-miR-1290	CLIP-seq
MIRT1207001	hsa-miR-1299	CLIP-seq
MIRT1207002	hsa-miR-198	CLIP-seq
MIRT1207003	hsa-miR-2053	CLIP-seq
MIRT1207004	hsa-miR-214	CLIP-seq
MIRT2059471	hsa-miR-28-3p	CLIP-seq
MIRT1207006	hsa-miR-29a	CLIP-seq
MIRT1207007	hsa-miR-29b	CLIP-seq
MIRT1207008	hsa-miR-29c	CLIP-seq
MIRT1207009	hsa-miR-3145-3p	CLIP-seq
MIRT1207010	hsa-miR-3148	CLIP-seq
MIRT1207011	hsa-miR-3167	CLIP-seq
MIRT1207012	hsa-miR-320a	CLIP-seq
MIRT1207013	hsa-miR-320b	CLIP-seq
MIRT1207014	hsa-miR-320c	CLIP-seq
MIRT1207015	hsa-miR-320d	CLIP-seq
MIRT1207016	hsa-miR-330-3p	CLIP-seq
MIRT1207019	hsa-miR-3619-5p	CLIP-seq
MIRT2586082	hsa-miR-3647-3p	CLIP-seq
MIRT1207022	hsa-miR-3689a-5p	CLIP-seq
MIRT1207023	hsa-miR-3689b	CLIP-seq
MIRT1207024	hsa-miR-3689e	CLIP-seq
MIRT1207025	hsa-miR-3689f	CLIP-seq
MIRT2586083	hsa-miR-371-5p	CLIP-seq
MIRT2586084	hsa-miR-371b-5p	CLIP-seq
MIRT2586085	hsa-miR-374c	CLIP-seq
MIRT1207027	hsa-miR-3908	CLIP-seq
MIRT1207029	hsa-miR-3942-5p	CLIP-seq
MIRT1207030	hsa-miR-3977	CLIP-seq
MIRT1207031	hsa-miR-4252	CLIP-seq
MIRT1207034	hsa-miR-4429	CLIP-seq
MIRT1207035	hsa-miR-4484	CLIP-seq
MIRT1207037	hsa-miR-4530	CLIP-seq
MIRT2287914	hsa-miR-4659a-3p	CLIP-seq
MIRT2287915	hsa-miR-4659b-3p	CLIP-seq
MIRT1207038	hsa-miR-4677-3p	CLIP-seq
MIRT1207039	hsa-miR-4679	CLIP-seq
MIRT1207040	hsa-miR-4703-5p	CLIP-seq
MIRT2287916	hsa-miR-4712-5p	CLIP-seq
MIRT1207041	hsa-miR-4717-5p	CLIP-seq
MIRT2586086	hsa-miR-4753-3p	CLIP-seq
MIRT2586087	hsa-miR-4762-3p	CLIP-seq
MIRT1207042	hsa-miR-4766-3p	CLIP-seq
MIRT2059476	hsa-miR-4766-5p	CLIP-seq
MIRT1207043	hsa-miR-4775	CLIP-seq
MIRT1207044	hsa-miR-4778-5p	CLIP-seq
MIRT1207045	hsa-miR-4782-5p	CLIP-seq
MIRT1207046	hsa-miR-4788	CLIP-seq
MIRT2586088	hsa-miR-506	CLIP-seq
MIRT2059478	hsa-miR-5096	CLIP-seq
MIRT2287917	hsa-miR-513c	CLIP-seq
MIRT2287918	hsa-miR-514b-5p	CLIP-seq
MIRT2059479	hsa-miR-516a-3p	CLIP-seq
MIRT1207048	hsa-miR-516b	CLIP-seq
MIRT1207049	hsa-miR-520a-5p	CLIP-seq
MIRT1207050	hsa-miR-525-5p	CLIP-seq
MIRT1207051	hsa-miR-548an	CLIP-seq
MIRT2059483	hsa-miR-554	CLIP-seq
MIRT1207052	hsa-miR-569	CLIP-seq
MIRT2059484	hsa-miR-593	CLIP-seq
MIRT1207053	hsa-miR-603	CLIP-seq
MIRT2586089	hsa-miR-655	CLIP-seq
MIRT1207055	hsa-miR-761	CLIP-seq
MIRT1207056	hsa-miR-767-5p	CLIP-seq
MIRT2287919	hsa-miR-770-5p	CLIP-seq
MIRT1207058	hsa-miR-876-5p	CLIP-seq
MIRT2287920	hsa-miR-942	CLIP-seq
MIRT2586081	hsa-miR-124	CLIP-seq
MIRT1207004	hsa-miR-214	CLIP-seq
MIRT2059471	hsa-miR-28-3p	CLIP-seq
MIRT1207009	hsa-miR-3145-3p	CLIP-seq
MIRT1207010	hsa-miR-3148	CLIP-seq
MIRT1207019	hsa-miR-3619-5p	CLIP-seq
MIRT1207022	hsa-miR-3689a-5p	CLIP-seq
MIRT1207023	hsa-miR-3689b	CLIP-seq
MIRT1207024	hsa-miR-3689e	CLIP-seq
MIRT1207025	hsa-miR-3689f	CLIP-seq
MIRT2586083	hsa-miR-371-5p	CLIP-seq
MIRT2586084	hsa-miR-371b-5p	CLIP-seq
MIRT2586085	hsa-miR-374c	CLIP-seq
MIRT1207027	hsa-miR-3908	CLIP-seq
MIRT1207029	hsa-miR-3942-5p	CLIP-seq
MIRT1207031	hsa-miR-4252	CLIP-seq
MIRT1207037	hsa-miR-4530	CLIP-seq
MIRT2287914	hsa-miR-4659a-3p	CLIP-seq
MIRT2287915	hsa-miR-4659b-3p	CLIP-seq
MIRT1207038	hsa-miR-4677-3p	CLIP-seq
MIRT1207039	hsa-miR-4679	CLIP-seq
MIRT1207040	hsa-miR-4703-5p	CLIP-seq
MIRT2287916	hsa-miR-4712-5p	CLIP-seq
MIRT1207041	hsa-miR-4717-5p	CLIP-seq
MIRT2586086	hsa-miR-4753-3p	CLIP-seq
MIRT1207042	hsa-miR-4766-3p	CLIP-seq
MIRT1207044	hsa-miR-4778-5p	CLIP-seq
MIRT2586088	hsa-miR-506	CLIP-seq
MIRT2059478	hsa-miR-5096	CLIP-seq
MIRT2287917	hsa-miR-513c	CLIP-seq
MIRT2287918	hsa-miR-514b-5p	CLIP-seq
MIRT2059479	hsa-miR-516a-3p	CLIP-seq
MIRT1207051	hsa-miR-548an	CLIP-seq
MIRT2059483	hsa-miR-554	CLIP-seq
MIRT2059484	hsa-miR-593	CLIP-seq
MIRT2586089	hsa-miR-655	CLIP-seq
MIRT1207055	hsa-miR-761	CLIP-seq
MIRT2287919	hsa-miR-770-5p	CLIP-seq
MIRT2287920	hsa-miR-942	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004579	Function	Dolichyl-diphosphooligosaccharide-protein glycotransferase activity	IC	15835887
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	21768116
GO:0005789	Component	Endoplasmic reticulum membrane	NAS	31831667
GO:0006486	Process	Protein glycosylation	IEA
GO:0006487	Process	Protein N-linked glycosylation	NAS	31831667
GO:0008250	Component	Oligosaccharyltransferase complex	IBA
GO:0008250	Component	Oligosaccharyltransferase complex	IDA	15835887, 28860277
GO:0008250	Component	Oligosaccharyltransferase complex	IEA
GO:0008250	Component	Oligosaccharyltransferase complex	NAS	31831667
GO:0016020	Component	Membrane	IEA
GO:0018279	Process	Protein N-linked glycosylation via asparagine	IDA	28860277
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	28860277
GO:0160226	Component	Oligosaccharyltransferase complex A	IDA	31831667, 36697828, 38670073

Other IDs

• MIM: 619023
• HGNC: 24448
• e!Ensembl: ENSG00000198856

Protein

• UniProt ID: Q9NRP0
• Protein name: Oligosaccharyltransferase complex subunit OSTC (Hydrophobic protein HSF-28)
• Protein function: Subunit of STT3A-containing oligosaccharyl transferase (OST-A) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an
• PDB: 6S7O, 8B6L, 8PN9
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04756	OST3_OST6	9 → 148	OST3 / OST6 family, transporter family	Family

• Sequence:

  METLYRVPFLVLECPNLKLKKPPWLHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVG
  SMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLL
  LFIGFVCVLLSFFMARVFMRMKLPGYLMG

• Sequence length: 149

Pathways

KEGG:

N-Glycan biosynthesis
Various types of N-glycan biosynthesis
Protein processing in endoplasmic reticulum