INIP (INTS3 and NABP interacting protein)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 58493
Gene name INTS3 and NABP interacting protein
Gene symbol INIP
Synonyms (NCBI Gene)
C9orf80HSPC043MISESOSSCSSBIP1hSSBIP1
Chromosome 9
Chromosome location 9q32
Summary The protein encoded by this gene is a subunit of single-stranded DNA binding complexes that are important for maintaining genome stability. These complexes are involved in G2/M checkpoint control and homologous recombination repair. [provided by RefSeq, J
miRNA miRNA information provided by mirtarbase database.
106
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (106)
miRTarBase ID miRNA Experiments Reference
MIRT024664 hsa-miR-215-5p Microarray 19074876
MIRT026602 hsa-miR-192-5p Microarray 19074876
MIRT639363 hsa-miR-500a-5p HITS-CLIP 23824327
MIRT639362 hsa-miR-501-5p HITS-CLIP 23824327
MIRT662897 hsa-miR-335-5p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (18)
GO ID Ontology Definition Evidence Reference
GO:0000724 Process Double-strand break repair via homologous recombination IDA 19683501
GO:0005515 Function Protein binding IPI 19683501, 25416956, 29892012, 32296183
GO:0005634 Component Nucleus IDA 19605351, 19683501
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
613273 24994 ENSG00000148153
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NRY2
Protein name SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1) (hSSBIP1)
Protein function Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in
PDB 4OWT , 4OWW , 8RBZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15925 SOSSC 18 → 101 SOSS complex subunit C Family
Sequence
Sequence length 104
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
INIP-related disorder Likely benign rs150494593 RCV003909747
Show/Hide Text Mining Associations (2)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Chromosomal Instability Associate 19605351
Drug Hypersensitivity Associate 19605351