Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	58491
Gene name	Zinc finger protein 71
Gene symbol	ZNF71
Synonyms (NCBI Gene)	EZFIT
Chromosome	19
Chromosome location	19q13.43

169

Show/Hide all (169)

miRTarBase ID	miRNA	Experiments	Reference
MIRT041568	hsa-miR-193b-3p	CLASH	23622248
MIRT710747	hsa-miR-590-3p	HITS-CLIP	19536157
MIRT710746	hsa-miR-6765-3p	HITS-CLIP	19536157
MIRT710745	hsa-miR-4735-5p	HITS-CLIP	19536157
MIRT710744	hsa-miR-4794	HITS-CLIP	19536157
MIRT710743	hsa-miR-664a-5p	HITS-CLIP	19536157
MIRT710742	hsa-miR-4775	HITS-CLIP	19536157
MIRT710740	hsa-miR-4263	HITS-CLIP	19536157
MIRT710741	hsa-miR-576-5p	HITS-CLIP	19536157
MIRT540466	hsa-miR-4781-3p	PAR-CLIP	21572407
MIRT540465	hsa-miR-3135a	PAR-CLIP	21572407
MIRT540464	hsa-miR-31-3p	PAR-CLIP	21572407
MIRT540463	hsa-miR-431-5p	PAR-CLIP	21572407
MIRT540462	hsa-miR-6501-5p	PAR-CLIP	21572407
MIRT540461	hsa-miR-4423-5p	PAR-CLIP	21572407
MIRT540460	hsa-miR-744-3p	PAR-CLIP	21572407
MIRT540459	hsa-miR-4774-3p	PAR-CLIP	21572407
MIRT529964	hsa-miR-298	PAR-CLIP	22012620
MIRT529963	hsa-miR-1273h-3p	PAR-CLIP	22012620
MIRT529962	hsa-miR-3678-3p	PAR-CLIP	22012620
MIRT529961	hsa-miR-6516-5p	PAR-CLIP	22012620
MIRT710747	hsa-miR-590-3p	HITS-CLIP	19536157
MIRT710746	hsa-miR-6765-3p	HITS-CLIP	19536157
MIRT710745	hsa-miR-4735-5p	HITS-CLIP	19536157
MIRT710744	hsa-miR-4794	HITS-CLIP	19536157
MIRT710743	hsa-miR-664a-5p	HITS-CLIP	19536157
MIRT710742	hsa-miR-4775	HITS-CLIP	19536157
MIRT710740	hsa-miR-4263	HITS-CLIP	19536157
MIRT710741	hsa-miR-576-5p	HITS-CLIP	19536157
MIRT540466	hsa-miR-4781-3p	PAR-CLIP	21572407
MIRT540465	hsa-miR-3135a	PAR-CLIP	21572407
MIRT540464	hsa-miR-31-3p	PAR-CLIP	21572407
MIRT540463	hsa-miR-431-5p	PAR-CLIP	21572407
MIRT540462	hsa-miR-6501-5p	PAR-CLIP	21572407
MIRT540461	hsa-miR-4423-5p	PAR-CLIP	21572407
MIRT540460	hsa-miR-744-3p	PAR-CLIP	21572407
MIRT540459	hsa-miR-4774-3p	PAR-CLIP	21572407
MIRT529964	hsa-miR-298	PAR-CLIP	22012620
MIRT529963	hsa-miR-1273h-3p	PAR-CLIP	22012620
MIRT529962	hsa-miR-3678-3p	PAR-CLIP	22012620
MIRT529961	hsa-miR-6516-5p	PAR-CLIP	22012620
MIRT1537135	hsa-miR-1237	CLIP-seq
MIRT1537136	hsa-miR-1248	CLIP-seq
MIRT1537137	hsa-miR-1912	CLIP-seq
MIRT1537138	hsa-miR-208a	CLIP-seq
MIRT1537139	hsa-miR-208b	CLIP-seq
MIRT1537140	hsa-miR-214	CLIP-seq
MIRT1537141	hsa-miR-3122	CLIP-seq
MIRT1537142	hsa-miR-3127-5p	CLIP-seq
MIRT1537143	hsa-miR-3130-5p	CLIP-seq
MIRT1537144	hsa-miR-3202	CLIP-seq
MIRT1537145	hsa-miR-340	CLIP-seq
MIRT1537146	hsa-miR-3617	CLIP-seq
MIRT1537147	hsa-miR-3619-5p	CLIP-seq
MIRT1537148	hsa-miR-3689a-3p	CLIP-seq
MIRT1537149	hsa-miR-3689c	CLIP-seq
MIRT1537150	hsa-miR-3913-5p	CLIP-seq
MIRT1537151	hsa-miR-3918	CLIP-seq
MIRT1537152	hsa-miR-3974	CLIP-seq
MIRT1537153	hsa-miR-4475	CLIP-seq
MIRT1537154	hsa-miR-4476	CLIP-seq
MIRT1537155	hsa-miR-4482	CLIP-seq
MIRT1537156	hsa-miR-4521	CLIP-seq
MIRT1537157	hsa-miR-4728-5p	CLIP-seq
MIRT1537158	hsa-miR-4749-3p	CLIP-seq
MIRT1537159	hsa-miR-499-5p	CLIP-seq
MIRT1537160	hsa-miR-641	CLIP-seq
MIRT1537161	hsa-miR-761	CLIP-seq
MIRT2162297	hsa-miR-1269	CLIP-seq
MIRT2162298	hsa-miR-1269b	CLIP-seq
MIRT2162299	hsa-miR-338-3p	CLIP-seq
MIRT2162300	hsa-miR-432	CLIP-seq
MIRT2162301	hsa-miR-4529-3p	CLIP-seq
MIRT1537158	hsa-miR-4749-3p	CLIP-seq
MIRT2162302	hsa-miR-617	CLIP-seq
MIRT2381404	hsa-miR-106a	CLIP-seq
MIRT2381405	hsa-miR-106b	CLIP-seq
MIRT2381406	hsa-miR-122	CLIP-seq
MIRT2162297	hsa-miR-1269	CLIP-seq
MIRT2162298	hsa-miR-1269b	CLIP-seq
MIRT2381407	hsa-miR-17	CLIP-seq
MIRT2381408	hsa-miR-20a	CLIP-seq
MIRT2381409	hsa-miR-20b	CLIP-seq
MIRT2381410	hsa-miR-2110	CLIP-seq
MIRT2381411	hsa-miR-24	CLIP-seq
MIRT2381412	hsa-miR-2467-5p	CLIP-seq
MIRT2381413	hsa-miR-3150a-3p	CLIP-seq
MIRT2381414	hsa-miR-3160-5p	CLIP-seq
MIRT2381415	hsa-miR-3173-3p	CLIP-seq
MIRT2381416	hsa-miR-3188	CLIP-seq
MIRT2381417	hsa-miR-3190	CLIP-seq
MIRT2162299	hsa-miR-338-3p	CLIP-seq
MIRT2381418	hsa-miR-34b	CLIP-seq
MIRT2381419	hsa-miR-3911	CLIP-seq
MIRT2381420	hsa-miR-3975	CLIP-seq
MIRT2381421	hsa-miR-4260	CLIP-seq
MIRT2381422	hsa-miR-4271	CLIP-seq
MIRT2381423	hsa-miR-4303	CLIP-seq
MIRT2162300	hsa-miR-432	CLIP-seq
MIRT2381424	hsa-miR-4325	CLIP-seq
MIRT2381425	hsa-miR-4418	CLIP-seq
MIRT2381426	hsa-miR-4428	CLIP-seq
MIRT2162301	hsa-miR-4529-3p	CLIP-seq
MIRT2381427	hsa-miR-4649-3p	CLIP-seq
MIRT2381428	hsa-miR-4725-3p	CLIP-seq
MIRT2381429	hsa-miR-4762-3p	CLIP-seq
MIRT2381430	hsa-miR-4797-3p	CLIP-seq
MIRT2381431	hsa-miR-485-5p	CLIP-seq
MIRT2381432	hsa-miR-509-3-5p	CLIP-seq
MIRT2381433	hsa-miR-509-5p	CLIP-seq
MIRT2381434	hsa-miR-519a	CLIP-seq
MIRT2381435	hsa-miR-519b-3p	CLIP-seq
MIRT2381436	hsa-miR-519c-3p	CLIP-seq
MIRT2381437	hsa-miR-519d	CLIP-seq
MIRT2381438	hsa-miR-574-5p	CLIP-seq
MIRT2162302	hsa-miR-617	CLIP-seq
MIRT2381439	hsa-miR-875-3p	CLIP-seq
MIRT2381440	hsa-miR-93	CLIP-seq
MIRT2397708	hsa-miR-1202	CLIP-seq
MIRT2397709	hsa-miR-1205	CLIP-seq
MIRT2162297	hsa-miR-1269	CLIP-seq
MIRT2162298	hsa-miR-1269b	CLIP-seq
MIRT2397710	hsa-miR-1909	CLIP-seq
MIRT2397711	hsa-miR-3194-5p	CLIP-seq
MIRT2162299	hsa-miR-338-3p	CLIP-seq
MIRT2397712	hsa-miR-3972	CLIP-seq
MIRT2162300	hsa-miR-432	CLIP-seq
MIRT2381425	hsa-miR-4418	CLIP-seq
MIRT2162301	hsa-miR-4529-3p	CLIP-seq
MIRT2381432	hsa-miR-509-3-5p	CLIP-seq
MIRT2381433	hsa-miR-509-5p	CLIP-seq
MIRT2162302	hsa-miR-617	CLIP-seq
MIRT2441880	hsa-miR-15a	CLIP-seq
MIRT2441881	hsa-miR-15b	CLIP-seq
MIRT2441882	hsa-miR-16	CLIP-seq
MIRT2441883	hsa-miR-195	CLIP-seq
MIRT1537140	hsa-miR-214	CLIP-seq
MIRT2441884	hsa-miR-3120-3p	CLIP-seq
MIRT1537144	hsa-miR-3202	CLIP-seq
MIRT1537147	hsa-miR-3619-5p	CLIP-seq
MIRT2441885	hsa-miR-424	CLIP-seq
MIRT1537153	hsa-miR-4475	CLIP-seq
MIRT1537154	hsa-miR-4476	CLIP-seq
MIRT2441886	hsa-miR-497	CLIP-seq
MIRT1537161	hsa-miR-761	CLIP-seq
MIRT2162297	hsa-miR-1269	CLIP-seq
MIRT2162298	hsa-miR-1269b	CLIP-seq
MIRT2162299	hsa-miR-338-3p	CLIP-seq
MIRT2162300	hsa-miR-432	CLIP-seq
MIRT2162301	hsa-miR-4529-3p	CLIP-seq
MIRT2162302	hsa-miR-617	CLIP-seq
MIRT2162297	hsa-miR-1269	CLIP-seq
MIRT2162298	hsa-miR-1269b	CLIP-seq
MIRT2162299	hsa-miR-338-3p	CLIP-seq
MIRT2162300	hsa-miR-432	CLIP-seq
MIRT2162301	hsa-miR-4529-3p	CLIP-seq
MIRT2162302	hsa-miR-617	CLIP-seq
MIRT2162297	hsa-miR-1269	CLIP-seq
MIRT2162298	hsa-miR-1269b	CLIP-seq
MIRT2162299	hsa-miR-338-3p	CLIP-seq
MIRT2162300	hsa-miR-432	CLIP-seq
MIRT2162301	hsa-miR-4529-3p	CLIP-seq
MIRT2162302	hsa-miR-617	CLIP-seq
MIRT2162297	hsa-miR-1269	CLIP-seq
MIRT2162298	hsa-miR-1269b	CLIP-seq
MIRT2162299	hsa-miR-338-3p	CLIP-seq
MIRT2162300	hsa-miR-432	CLIP-seq
MIRT2162301	hsa-miR-4529-3p	CLIP-seq
MIRT2162302	hsa-miR-617	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	28514442, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
194545	13141	ENSG00000197951

Q9NQZ8

Protein name

Endothelial zinc finger protein induced by tumor necrosis factor alpha (Zinc finger protein 71)

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00096	zf-C2H2	130 → 152	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	158 → 180	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	186 → 208	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	214 → 236	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	242 → 264	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	270 → 292	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	298 → 320	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	326 → 348	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	354 → 376	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	382 → 404	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	410 → 432	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	438 → 460	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	466 → 488	Zinc finger, C2H2 type	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in placenta, followed by brain, testis, pancreas, heart, small intestine, muscle, uterus, prostate and peripheral blood leukocytes. Not detected in liver, lung, colon, stomach, salivary and thyroid gland.

Sequence

MKELDPKNDISEDKLSVVGEATGGPTRNGARGPGSEGVWEPGSWPERPRGDAGAEWEPLG
IPQGNKLLGGSVPACHELKAFANQGCVLVPPRLDDPTEKGACPPVRRGKNFSSTSDLSKP
PMPCEEKKTYDCSECGKAFSRSSSLIKHQRIHTGEKPFECDTCGKHFIERSSLTIHQRVH
TGEKPYACGDCGKAFSQRMNLTVHQRTHTGEKPYVCDVCGKAFRKTSSLTQHERIHTGEK
PYACGDCGKAFSQNMHLIVHQRTHTGEKPYVCPECGRAFSQNMHLTEHQRTHTGEKPYAC
KECGKAFNKSSSLTLHQRNHTGEKPYVCGECGKAFSQSSYLIQHQRFHIGVKPFECSECG
KAFSKNSSLTQHQRIHTGEKPYECYICKKHFTGRSSLIVHQIVHTGEKPYVCGECGKAFS
QSAYLIEHQRIHTGEKPYRCGQCGKSFIKNSSLTVHQRIHTGEKPYRCGECGKTFSRNTN
LTRHLRIHT

Sequence length

489

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
INSOMNIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Carcinoma Non Small Cell Lung	Associate	29861409, 33916522, 36499305	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasm Metastasis	Inhibit	36369089	★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Associate	36369089	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF71 (zinc finger protein 71)