Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Breast cancer |
Malignant neoplasm of breast |
rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243 View all (309 more) |
23535729 |
Breast carcinoma |
Breast Carcinoma |
rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038 View all (71 more) |
29059683, 23535729, 25751625 |
Diffuse lymphoma |
Diffuse Large B-Cell Lymphoma |
rs121912651, rs121913289, rs121913293, rs878854402, rs869025340, rs1349928568, rs1569115687, rs121913291 |
25261932 |
Hypothyroidism |
Hypothyroidism |
rs869320723, rs121908862, rs121908863, rs121908865, rs121908866, rs121908867, rs121908870, rs121908871, rs121908872, rs2140110277, rs121908881, rs121908884, rs121908885, rs786205080, rs1586182912, rs121917847, rs104893655, rs104893657, rs104893658, rs104893659, rs104893660, rs104893656, rs121917719, rs786204790, rs189261858, rs879255608, rs868197660, rs879255609, rs1586744173, rs1586182837, rs771222349, rs1587618417, rs1601844140, rs760832986, rs780982673, rs1603336347, rs1691155605 View all (22 more) |
30595370 |
Immunoglobulin a deficiency |
Immunoglobulin A deficiency (disorder) |
rs72553883, rs72553882, rs144718007 |
27723758 |
Lung adenocarcinoma |
Adenocarcinoma of lung (disorder) |
rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370, rs760043106, rs1057519788, rs1131692238, rs1131692237, rs1554350382 View all (5 more) |
28604730 |
Multiple myeloma |
Multiple Myeloma |
rs11540652, rs78311289, rs121913482, rs397507340, rs121913343, rs121913240, rs121913529, rs730882018, rs1057517992, rs121913527, rs756183569, rs746646631, rs1574706907, rs372078034, rs745380962, rs751524927, rs1575079076, rs1575446356, rs1478603808, rs1578264146, rs1578673280, rs1579484570, rs1579491104, rs1171390403, rs1582867955, rs764264135, rs951047896, rs890521687, rs1581495906, rs1587941402, rs1003155450, rs1588299621, rs1591100766, rs1591693095, rs1029296641, rs1593107841, rs1208575764, rs1593835248, rs1594406727, rs1594966387, rs1595889508, rs1159294530, rs1597073318, rs1135402871, rs1599413207, rs1418268495, rs1212577459, rs1600394490, rs1455074519, rs1603113792, rs1603415028, rs1602247047, rs1603452612 View all (38 more) |
28112199 |
Multiple sclerosis |
Multiple Sclerosis |
rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039, rs483353038, rs61731956, rs568165874, rs767480544 View all (4 more) |
21833088, 24076602 |
Renal carcinoma |
Renal Cell Carcinoma |
rs121913668, rs121913670, rs121913243, rs786202724 |
24220699 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Hodgkin lymphoma |
Adult Hodgkin Lymphoma |
|
21037568 |
ClinVar |
Eczema |
Eczema |
|
|
GWAS |
Asthma |
Asthma |
|
|
GWAS |
Multiple Sclerosis |
Multiple Sclerosis |
|
|
GWAS |
Biliary Cirrhosis |
Biliary Cirrhosis |
|
|
GWAS |
Allergic Sensitization |
Allergic Sensitization |
|
|
GWAS |
Follicular lymphoma |
Follicular lymphoma |
|
|
GWAS |
Crohn Disease |
Crohn Disease |
|
|
GWAS |
Neuroblastoma |
Neuroblastoma |
Loss of SNAI2 function reduces self-renewal, 3D invasion as well as metastatic spread in vivo, while strongly sensitizing neuroblastoma cells to RA-induced growth inhibition. |
|
GWAS, CBGDA |
Central Nervous System Lymphoma |
Central Nervous System Lymphoma |
|
|
GWAS |
Systemic lupus erythematosus |
Systemic lupus erythematosus |
|
|
GWAS |
Ovarian cancer |
Ovarian cancer |
Conditional KD of IL6 in the OCCA xenograft model delays tumor growth |
|
GWAS, CBGDA |
Colorectal Cancer |
Colorectal Cancer |
In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. |
|
GWAS, CBGDA |
Hyperthyroidism |
Hyperthyroidism |
|
|
GWAS |
Carcinoma |
Carcinoma |
|
|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Acute Kidney Injury |
Associate
|
30126849 |
Adenocarcinoma |
Associate
|
29948619, 33318305 |
Adenocarcinoma of Lung |
Stimulate
|
31986409 |
Adenocarcinoma of Lung |
Associate
|
35435126 |
Adenomatous Polyps |
Associate
|
34200314 |
Adenomyosis |
Associate
|
33728345 |
Anophthalmia with pulmonary hypoplasia |
Associate
|
39376555 |
Aortic Aneurysm Abdominal |
Associate
|
34898354 |
Arteriosclerosis Obliterans |
Associate
|
37744231 |
Asthma |
Associate
|
27484035, 33825599, 35417913 |
Astrocytoma |
Associate
|
20068183 |
Atrial Fibrillation |
Associate
|
34514000, 36065882 |
Behcet Syndrome |
Associate
|
39317938 |
Breast Neoplasms |
Associate
|
25033876, 28187158, 28235236, 28849135, 30371726, 30573632, 33327894, 35524174, 36376369, 36941464, 37009655, 37536436, 39645013, 40114244, 40684233 |
Breast Neoplasms |
Stimulate
|
33670447 |
Burkitt Lymphoma |
Associate
|
1406658, 37689284 |
Cap Myopathy |
Associate
|
32059012 |
Carcinogenesis |
Associate
|
2470097, 25400777, 26427660, 27283940, 27366943, 29286144, 29445147, 29749550, 30475759, 32992461, 37573419 |
Carcinoma Basal Cell |
Stimulate
|
40684233 |
Carcinoma Hepatocellular |
Associate
|
27495068, 28656879, 28800314, 29047230, 29749550, 30670911, 32156248, 34957996, 36418931, 36524545 |
Carcinoma Non Small Cell Lung |
Stimulate
|
25400777, 26490983 |
Carcinoma Non Small Cell Lung |
Associate
|
30832754, 31326971, 31707347, 33896835 |
Carcinoma Ovarian Epithelial |
Associate
|
27827314 |
Carcinoma Pancreatic Ductal |
Associate
|
30475759, 36724291 |
Carcinoma Renal Cell |
Associate
|
24220699, 27366943, 27774982, 33121461, 33453148, 35441392, 37848987 |
Carcinoma Renal Cell |
Stimulate
|
29081406 |
Carcinoma Squamous Cell |
Associate
|
32108138, 34112238, 35273591, 36894542 |
Cardiovascular Diseases |
Stimulate
|
35038974 |
Cataract |
Associate
|
31755246 |
Cholangiocarcinoma |
Associate
|
30305026 |
Colitis Ulcerative |
Associate
|
37445676 |
Colonic Neoplasms |
Associate
|
29948619 |
Colonic Polyps |
Associate
|
37573419 |
Colorectal Neoplasms |
Associate
|
24196785, 29512788, 29552759, 29693171, 29948619, 30504754, 31125260, 33148262, 33277837, 33455104, 33907219, 34200314, 34418232, 36366788, 37573419 |
Colorectal Neoplasms |
Stimulate
|
30922567 |
Constriction Pathologic |
Associate
|
22173169 |
Coronary Artery Disease |
Associate
|
32572930, 37744231 |
Coronary Restenosis |
Associate
|
35328496 |
Diabetes Complications |
Associate
|
35451342 |
Diabetes Gestational |
Associate
|
31627090 |
Diabetes Mellitus |
Associate
|
17881614, 30126849 |
Diabetes Mellitus Type 1 |
Associate
|
17881614 |
Diabetes Mellitus Type 2 |
Associate
|
17881614, 21526116 |
Diabetic Nephropathies |
Associate
|
21526116 |
Diabetic Nephropathies |
Stimulate
|
33408314 |
Diabetic Retinopathy |
Stimulate
|
35451342 |
Drug Hypersensitivity |
Associate
|
35274773 |
Encephalomyelitis Autoimmune Experimental |
Associate
|
34555308 |
Esophageal Neoplasms |
Associate
|
28404954, 36624401, 37263709 |
Esophageal Squamous Cell Carcinoma |
Associate
|
27966444, 34586751, 35913453, 36624401 |
Esophageal Squamous Cell Carcinoma |
Stimulate
|
28404954 |
Essential Hypertension |
Associate
|
35036445 |
Fetal Growth Retardation |
Associate
|
36047133 |
Fibrosis |
Inhibit
|
32921988 |
Fibrosis |
Associate
|
33408314, 39320020 |
Fractures Bone |
Associate
|
34592894 |
Gallbladder Neoplasms |
Stimulate
|
33067424 |
Genomic Instability |
Associate
|
17908964 |
Glioblastoma |
Associate
|
31865777 |
Glioblastoma |
Stimulate
|
38287522 |
Glioma |
Associate
|
28351322, 29046366, 30347597, 30832754, 30909189, 31696483, 31957841, 34288803, 37202742, 38287522 |
Guillain Barre Syndrome |
Stimulate
|
34373511 |
Hereditary Breast and Ovarian Cancer Syndrome |
Associate
|
17908964, 37009655 |
Hodgkin Disease |
Associate
|
21037568, 37689284 |
Hypercalcemia |
Stimulate
|
33910638 |
Hyperglycemia |
Associate
|
31625803 |
Hyperparathyroidism Primary |
Associate
|
33910638 |
Hypertension |
Associate
|
35036445 |
Hypertension Pregnancy Induced |
Inhibit
|
36047133 |
Inflammation |
Associate
|
30126849, 30305026, 33174011, 35038974, 35119126, 35274773, 36440209, 40289758 |
Inflammation |
Stimulate
|
34898354 |
Intra Articular Fractures |
Associate
|
34592894 |
Intracranial Aneurysm |
Associate
|
33750300, 40289758 |
Kidney Diseases |
Associate
|
32921988 |
Kidney Failure Chronic |
Associate
|
17881614, 21526116 |
Kidney Neoplasms |
Associate
|
27774982 |
Leukemia |
Associate
|
26545364 |
Leukemia Myeloid Acute |
Associate
|
29467491, 34871521, 36718632 |
Leukemia Promyelocytic Acute |
Associate
|
26545364 |
Leukemia T Cell |
Associate
|
1406658 |
Lung Neoplasms |
Stimulate
|
25400777 |
Lung Neoplasms |
Associate
|
33902331, 33907219, 35025697 |
Lymphatic Metastasis |
Stimulate
|
25400777, 26490983, 27775803, 36624401 |
Lymphatic Metastasis |
Associate
|
29552759, 30679629, 32664121, 36894542 |
Lymphoma |
Associate
|
35049170 |
Lymphoma |
Inhibit
|
37689284 |
Lymphoma B Cell |
Associate
|
37689284 |
Lymphoma Follicular |
Associate
|
25279986 |
Lymphoma Large B Cell Diffuse |
Associate
|
37689284 |
Lymphoma Non Hodgkin |
Associate
|
39849875 |
Medulloblastoma |
Associate
|
22832581 |
Melanoma |
Stimulate
|
28265576, 28409552 |
Melanoma |
Associate
|
29286144 |
Mesothelioma |
Associate
|
23626673, 34859258 |
Mesothelioma Malignant |
Associate
|
23626673, 24926545, 34859258 |
Metabolic Diseases |
Associate
|
30126849 |
Microvascular Angina |
Associate
|
36524545 |
Mohr Tranebjaerg syndrome |
Stimulate
|
31707347 |
Multiple Myeloma |
Associate
|
31221783, 32992461, 37496441 |
Multiple Organ Failure |
Associate
|
35119126 |
Nasopharyngeal Carcinoma |
Stimulate
|
29445147 |
Nasopharyngeal Carcinoma |
Associate
|
30141114 |
Nasopharyngeal Neoplasms |
Associate
|
30141114 |
Neoplasm Metastasis |
Associate
|
28656879, 29047230, 29081406, 29286144, 29552759, 30504754, 30679629, 31626590, 31865777, 32196583, 33109773, 34200314, 35820706, 36894542, 36941464 |
Neoplasm Metastasis |
Stimulate
|
29512788, 30922567, 31696483, 32249539, 33453148, 39376555 |
Neoplasms |
Associate
|
24196785, 25033876, 25933431, 26490983, 27232880, 27366943, 28187158, 28265576, 28276314, 28656879, 28719033, 29244840, 29445147, 29512788, 29552759, 29749550, 30126849, 30141114, 30670911, 30679629, 30767760, 30832754, 31556152, 31604907, 32058674, 32664121, 33008376, 33030666, 33067424, 33121461, 33318305, 33327894, 33430890, 33601175, 33728345, 33752525, 33902331, 33907219, 33910638, 33926464, 34040254, 34335862, 34859258, 34902986, 34946814, 35036445, 35388548, 35435126, 35664988, 35820706, 36139061, 36418931, 36718632, 36724291, 36882663, 36894542, 36941464, 37009655, 37202742, 37263709, 37573419, 37689284, 39376555 View all (48 more) |
Neoplasms |
Inhibit
|
28404954, 37496441 |
Neoplasms |
Stimulate
|
28800314, 28838211, 30468460, 30504754 |
Neuroendocrine Tumors |
Associate
|
30475759 |
Niemann Pick Disease Type C |
Associate
|
29445147 |
Non Muscle Invasive Bladder Neoplasms |
Stimulate
|
32664121 |
Nose Diseases |
Associate
|
35274773 |
Obesity |
Associate
|
35036445 |
Oral Submucous Fibrosis |
Associate
|
39320020 |
Osteoarthritis |
Stimulate
|
30126849, 33174011, 35399100, 35706414 |
Osteogenesis imperfecta type 1A |
Stimulate
|
40289758 |
Osteosarcoma |
Associate
|
27813492, 32249539 |
Osteosarcoma |
Stimulate
|
32196583, 32960485 |
Ovarian Neoplasms |
Associate
|
17908964, 26097562, 32441301, 32781203, 35820706, 38098223 |
Ovarian Neoplasms |
Stimulate
|
30468460 |
Pancreatic Neoplasms |
Stimulate
|
27028998, 39376555 |
Pancreatic Neoplasms |
Associate
|
30475759, 32499447, 33008376, 34245303, 36724291, 36882663 |
Pancreatitis |
Associate
|
36218109 |
Parathyroid Neoplasms |
Associate
|
33910638 |
Parkinson Disease |
Associate
|
34868009 |
Personality Disorders |
Associate
|
26703666, 33121461 |
Pituitary Neoplasms |
Associate
|
31604907, 37270938, 39290194 |
Plasmacytoma |
Associate
|
35049170 |
Polycystic Ovary Syndrome |
Associate
|
39773546 |
Polyps |
Stimulate
|
37573419 |
Polyradiculoneuropathy Chronic Inflammatory Demyelinating |
Stimulate
|
34373511 |
Pre Eclampsia |
Associate
|
31627090 |
Pre Eclampsia |
Inhibit
|
36047133 |
Prodromal Symptoms |
Associate
|
33148262 |
Prostatic Neoplasms |
Associate
|
21814516, 25149474, 25933431, 27693493, 27794184, 30914434, 31877167, 32059012, 32358016, 33430890, 33752525, 39183420 |
Prostatic Neoplasms |
Stimulate
|
26703666, 36053124 |
Prostatitis |
Associate
|
32680982 |
Pruritus |
Associate
|
35274773 |
Pulmonary Disease Chronic Obstructive |
Associate
|
30123065, 32342557 |
Pulmonary Fibrosis |
Associate
|
33601175 |
Purpura Thrombocytopenic Idiopathic |
Associate
|
34555308 |
Rhinitis Allergic |
Associate
|
35274773 |
Schizophrenia |
Inhibit
|
30560506 |
Sepsis |
Stimulate
|
35119126 |
Small Cell Lung Carcinoma |
Associate
|
23716474 |
Squamous Cell Carcinoma of Head and Neck |
Stimulate
|
31485648 |
Squamous Cell Carcinoma of Head and Neck |
Associate
|
34805417, 35398964, 36894542 |
Status Asthmaticus |
Associate
|
27484035 |
Stomach Neoplasms |
Associate
|
23801869, 30679629, 30832754, 31028131, 31556152, 31793989, 33277837, 33455104, 34876056, 35049170 |
Stomach Neoplasms |
Stimulate
|
29559849, 35664988 |
Stomach Neoplasms |
Inhibit
|
39578780 |
Sveinsson Chorioretinal Atrophy |
Stimulate
|
26990997 |
Systemic Inflammatory Response Syndrome |
Associate
|
30126849 |
Tertiary Lymphoid Structures |
Associate
|
34200314 |
Thyroid Cancer Papillary |
Stimulate
|
34927541 |
Thyroid Carcinoma Anaplastic |
Associate
|
35971932 |
Thyroid Neoplasms |
Associate
|
26427660, 33030666, 35388548 |
Thyroiditis |
Stimulate
|
26427660 |
Thyroiditis |
Associate
|
33030666 |
Triple Negative Breast Neoplasms |
Associate
|
30371726, 33327894, 40114244 |
Tuberculosis Multidrug Resistant |
Associate
|
29693171 |
Urinary Bladder Neoplasms |
Stimulate
|
26517688 |
Urinary Bladder Neoplasms |
Associate
|
32664121, 34902986 |
Urologic Neoplasms |
Associate
|
34335862 |
Uterine Cervical Neoplasms |
Stimulate
|
27775803 |
Uterine Cervical Neoplasms |
Associate
|
28276314, 31626590, 33109773, 38013620 |
Uveal melanoma |
Associate
|
31002139 |
|