PTPN13 (protein tyrosine phosphatase non-receptor type 13)

Gene

• Entrez ID: 5783
• Gene name: Protein tyrosine phosphatase non-receptor type 13
• Gene symbol: PTPN13
• Synonyms (NCBI Gene): FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E
• Chromosome: 4
• Chromosome location: 4q21.3
• Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005593	hsa-miR-200c-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	20620960
MIRT005593	hsa-miR-200c-3p	FACS, Luciferase reporter assay, qRT-PCR, Western blot	20620960
MIRT005894	hsa-miR-194-5p	Luciferase reporter assay, qRT-PCR, Western blot	20979124
MIRT005593	hsa-miR-200c-3p	Reporter assay	20620960
MIRT049422	hsa-miR-92a-3p	CLASH	23622248
MIRT045058	hsa-miR-186-5p	CLASH	23622248
MIRT043492	hsa-miR-331-3p	CLASH	23622248
MIRT213685	hsa-miR-26a-5p	Luciferase reporter assay, qRT-PCR, Western blot	27285768
MIRT213685	hsa-miR-26a-5p	Luciferase reporter assay, qRT-PCR, Western blot	27285768
MIRT1274839	hsa-miR-1297	CLIP-seq
MIRT1274840	hsa-miR-200b	CLIP-seq
MIRT1274841	hsa-miR-200c	CLIP-seq
MIRT1274842	hsa-miR-26a	CLIP-seq
MIRT1274843	hsa-miR-26b	CLIP-seq
MIRT1274844	hsa-miR-3120-3p	CLIP-seq
MIRT1274845	hsa-miR-320a	CLIP-seq
MIRT1274846	hsa-miR-320b	CLIP-seq
MIRT1274847	hsa-miR-320c	CLIP-seq
MIRT1274848	hsa-miR-320d	CLIP-seq
MIRT1274849	hsa-miR-429	CLIP-seq
MIRT1274850	hsa-miR-4310	CLIP-seq
MIRT1274851	hsa-miR-4429	CLIP-seq
MIRT1274852	hsa-miR-4465	CLIP-seq
MIRT1274853	hsa-miR-4693-5p	CLIP-seq
MIRT1274854	hsa-miR-4729	CLIP-seq
MIRT1274855	hsa-miR-498	CLIP-seq
MIRT1274856	hsa-miR-548c-3p	CLIP-seq
MIRT1274857	hsa-miR-616	CLIP-seq
MIRT1274840	hsa-miR-200b	CLIP-seq
MIRT1274841	hsa-miR-200c	CLIP-seq
MIRT1274845	hsa-miR-320a	CLIP-seq
MIRT1274846	hsa-miR-320b	CLIP-seq
MIRT1274847	hsa-miR-320c	CLIP-seq
MIRT1274848	hsa-miR-320d	CLIP-seq
MIRT1274849	hsa-miR-429	CLIP-seq
MIRT1274851	hsa-miR-4429	CLIP-seq
MIRT1274853	hsa-miR-4693-5p	CLIP-seq
MIRT1274854	hsa-miR-4729	CLIP-seq
MIRT1274857	hsa-miR-616	CLIP-seq
MIRT2080847	hsa-miR-30a	CLIP-seq
MIRT2080848	hsa-miR-30b	CLIP-seq
MIRT2080849	hsa-miR-30c	CLIP-seq
MIRT2080850	hsa-miR-30d	CLIP-seq
MIRT2080851	hsa-miR-30e	CLIP-seq
MIRT2306872	hsa-miR-101	CLIP-seq
MIRT1274839	hsa-miR-1297	CLIP-seq
MIRT2306873	hsa-miR-1322	CLIP-seq
MIRT2306874	hsa-miR-136	CLIP-seq
MIRT2306875	hsa-miR-144	CLIP-seq
MIRT1274840	hsa-miR-200b	CLIP-seq
MIRT1274841	hsa-miR-200c	CLIP-seq
MIRT1274842	hsa-miR-26a	CLIP-seq
MIRT1274843	hsa-miR-26b	CLIP-seq
MIRT2080847	hsa-miR-30a	CLIP-seq
MIRT2080848	hsa-miR-30b	CLIP-seq
MIRT2080849	hsa-miR-30c	CLIP-seq
MIRT2080850	hsa-miR-30d	CLIP-seq
MIRT2080851	hsa-miR-30e	CLIP-seq
MIRT2306876	hsa-miR-3163	CLIP-seq
MIRT1274845	hsa-miR-320a	CLIP-seq
MIRT1274846	hsa-miR-320b	CLIP-seq
MIRT1274847	hsa-miR-320c	CLIP-seq
MIRT1274848	hsa-miR-320d	CLIP-seq
MIRT2306877	hsa-miR-346	CLIP-seq
MIRT2306878	hsa-miR-4288	CLIP-seq
MIRT1274849	hsa-miR-429	CLIP-seq
MIRT1274851	hsa-miR-4429	CLIP-seq
MIRT1274852	hsa-miR-4465	CLIP-seq
MIRT1274853	hsa-miR-4693-5p	CLIP-seq
MIRT1274854	hsa-miR-4729	CLIP-seq
MIRT2306879	hsa-miR-4764-3p	CLIP-seq
MIRT2306880	hsa-miR-495	CLIP-seq
MIRT1274855	hsa-miR-498	CLIP-seq
MIRT1274857	hsa-miR-616	CLIP-seq
MIRT2306881	hsa-miR-632	CLIP-seq
MIRT2306882	hsa-miR-654-3p	CLIP-seq
MIRT2306883	hsa-miR-802	CLIP-seq
MIRT2306872	hsa-miR-101	CLIP-seq
MIRT2432327	hsa-miR-105	CLIP-seq
MIRT1274839	hsa-miR-1297	CLIP-seq
MIRT2306874	hsa-miR-136	CLIP-seq
MIRT2306875	hsa-miR-144	CLIP-seq
MIRT2432328	hsa-miR-194	CLIP-seq
MIRT1274840	hsa-miR-200b	CLIP-seq
MIRT1274841	hsa-miR-200c	CLIP-seq
MIRT1274842	hsa-miR-26a	CLIP-seq
MIRT1274843	hsa-miR-26b	CLIP-seq
MIRT2080847	hsa-miR-30a	CLIP-seq
MIRT2080848	hsa-miR-30b	CLIP-seq
MIRT2080849	hsa-miR-30c	CLIP-seq
MIRT2080850	hsa-miR-30d	CLIP-seq
MIRT2080851	hsa-miR-30e	CLIP-seq
MIRT2306876	hsa-miR-3163	CLIP-seq
MIRT1274845	hsa-miR-320a	CLIP-seq
MIRT1274846	hsa-miR-320b	CLIP-seq
MIRT1274847	hsa-miR-320c	CLIP-seq
MIRT1274848	hsa-miR-320d	CLIP-seq
MIRT2306877	hsa-miR-346	CLIP-seq
MIRT2432329	hsa-miR-410	CLIP-seq
MIRT2306878	hsa-miR-4288	CLIP-seq
MIRT1274849	hsa-miR-429	CLIP-seq
MIRT2432330	hsa-miR-433	CLIP-seq
MIRT1274851	hsa-miR-4429	CLIP-seq
MIRT1274852	hsa-miR-4465	CLIP-seq
MIRT1274854	hsa-miR-4729	CLIP-seq
MIRT2306879	hsa-miR-4764-3p	CLIP-seq
MIRT1274855	hsa-miR-498	CLIP-seq
MIRT2432331	hsa-miR-520d-5p	CLIP-seq
MIRT2432332	hsa-miR-524-5p	CLIP-seq
MIRT2432333	hsa-miR-548l	CLIP-seq
MIRT2432334	hsa-miR-548n	CLIP-seq
MIRT1274857	hsa-miR-616	CLIP-seq
MIRT2306881	hsa-miR-632	CLIP-seq
MIRT2306882	hsa-miR-654-3p	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
CEBPB	Unknown	11696979
NFKB1	Unknown	11696979;16306044
RELA	Unknown	11696979;16306044
STAT3	Activation	24191246
TP53	Unknown	11696979

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001933	Process	Negative regulation of protein phosphorylation	IMP	25893857
GO:0004721	Function	Phosphoprotein phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	IBA
GO:0004725	Function	Protein tyrosine phosphatase activity	IDA	14516276, 15611135, 19307596
GO:0004725	Function	Protein tyrosine phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	IMP	23604317
GO:0005515	Function	Protein binding	IPI	10826496, 10918185, 11356191, 12095257, 12724420, 14516276, 14698303, 17240990, 17657516, 18684861, 19307596, 23108400, 23604317, 23611113, 24316673
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	10826496, 11356191
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	14516276
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IDA	14516276
GO:0005886	Component	Plasma membrane	TAS
GO:0006470	Process	Protein dephosphorylation	IDA	17657516
GO:0016787	Function	Hydrolase activity	IEA
GO:0030027	Component	Lamellipodium	IDA	11356191
GO:0030027	Component	Lamellipodium	IEA
GO:0035335	Process	Peptidyl-tyrosine dephosphorylation	IMP	23604317
GO:0036312	Function	Phosphatidylinositol 3-kinase regulatory subunit binding	IBA
GO:0036312	Function	Phosphatidylinositol 3-kinase regulatory subunit binding	IPI	23604317
GO:0042995	Component	Cell projection	IEA
GO:0044297	Component	Cell body	IEA
GO:0051896	Process	Regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IBA
GO:0051896	Process	Regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA	23604317
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0097237	Process	Cellular response to toxic substance	IEA
GO:1904890	Process	Negative regulation of excitatory synapse assembly	IBA
GO:1904890	Process	Negative regulation of excitatory synapse assembly	IEA

Other IDs

• MIM: 600267
• HGNC: 9646
• e!Ensembl: ENSG00000163629

Protein

• UniProt ID: Q12923
• Protein name: Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
• Protein function: Tyrosine phosphatase which negatively regulates FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317). {EC
• PDB: 1D5G, 1Q7X, 1WCH, 2M0Z, 2M10, 3LNX, 3LNY, 3PDZ, 5GLJ, 7QCX, 7QCY, 7XTY
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF09379	FERM_N	576 → 638	FERM N-terminal domain	Domain
  PF00373	FERM_M	666 → 781	FERM central domain	Domain
  PF09380	FERM_C	787 → 876	FERM C-terminal PH-like domain	Domain
  PF00595	PDZ	1093 → 1176	PDZ domain	Domain
  PF16599	PTN13_u3	1177 → 1367		Family
  PF00595	PDZ	1368 → 1450	PDZ domain	Domain
  PF00595	PDZ	1501 → 1585	PDZ domain	Domain
  PF00595	PDZ	1788 → 1866	PDZ domain	Domain
  PF00595	PDZ	1883 → 1961	PDZ domain	Domain
  PF00102	Y_phosphatase	2237 → 2466	Protein-tyrosine phosphatase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in keratinocytes (at protein level) (PubMed:29043977). Present in most tissues with the exception of the liver and skeletal muscle. Most abundant in lung, kidney and fetal brain. {ECO:0000269|PubMed:29043977}.
• Sequence:

  MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
  SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
  PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
  SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
  MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
  SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
  PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
  IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
  KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
  PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
  VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
  KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
  VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
  HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
  GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
  FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
  EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
  LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR
  WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP
  GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM
  KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ
  VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD
  SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI
  SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN
  TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF
  EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA
  SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ
  PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH
  QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP
  QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG
  FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT
  VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA
  IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA
  PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE
  SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE
  DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER
  TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL
  QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI
  ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA
  LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR
  SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC
  YQVILYVLTRLQAEEEQKQQPQLLK

• Sequence length: 2485

Pathways

KEGG:

Apoptosis

Reactome:

Synthesis of PIPs at the plasma membrane
Interleukin-37 signaling

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Cervical cancer	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHRONIC KIDNEY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETIC NEPHROPATHY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
FAMILIAL LONG QT SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Likely benign; Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Meniere disease	Uncertain significance	ClinVar Disgenet	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Nonpapillary renal cell carcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Conflicting classifications of pathogenicity	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PTPN13-related disorder	Conflicting classifications of pathogenicity; Uncertain significance; Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Likely benign; Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Adenocarcinoma	Associate	26683690, 29884612	★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of Lung	Associate	24894543	★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Associate	31888563	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	12354757, 19004008, 22279592, 24338422	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Inhibit	24338422	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	26801674	★☆☆☆☆ Found in Text Mining only
Carcinoma Non Small Cell Lung	Associate	26252379, 29415055	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Associate	24191246, 26252379	★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Associate	15494722, 20039457	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	15494722, 15611135, 24338422, 33884652, 34045552	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Associate	38241313	★☆☆☆☆ Found in Text Mining only
Endodermal Sinus Tumor	Associate	16306258	★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Associate	38039548	★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Associate	38039548	★☆☆☆☆ Found in Text Mining only
Familial cylindromatosis	Associate	29884612	★☆☆☆☆ Found in Text Mining only
Hirschsprung Disease	Associate	29093530	★☆☆☆☆ Found in Text Mining only
Laryngeal Neoplasms	Associate	19892796	★☆☆☆☆ Found in Text Mining only
Leukemia Lymphoma Adult T Cell	Associate	11472346	★☆☆☆☆ Found in Text Mining only
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	23519466	★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Associate	39270538	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Associate	24191246, 25837438, 26683690, 31826912	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Stimulate	31888563, 33884652	★☆☆☆☆ Found in Text Mining only
Lymphoma Large B Cell Diffuse	Associate	26133246	★☆☆☆☆ Found in Text Mining only
Lymphoma Non Hodgkin	Associate	26133246	★☆☆☆☆ Found in Text Mining only
Lymphoma T Cell	Associate	9375749	★☆☆☆☆ Found in Text Mining only
Neoplasm Metastasis	Associate	38039548	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	11106428, 11472346, 15494722, 20620960, 24894543, 25837438, 26252379, 28010732, 29606096, 31826912, 33884652, 39208653	★☆☆☆☆ Found in Text Mining only
Neoplasms	Stimulate	16306044	★☆☆☆☆ Found in Text Mining only
Neoplasms	Inhibit	19004008, 22279592, 24191246, 26133246, 26801674, 8824809	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Associate	11290551, 8824809	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Inhibit	37895093	★☆☆☆☆ Found in Text Mining only
Peritoneal Neoplasms	Associate	26811494	★☆☆☆☆ Found in Text Mining only
Pharyngeal Neoplasms	Associate	19892796	★☆☆☆☆ Found in Text Mining only
Polycystic Kidney Autosomal Dominant	Associate	8824809	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	22274591, 23559010	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Associate	19892796	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Associate	26811494	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Associate	27339696	★☆☆☆☆ Found in Text Mining only