Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	57794
Gene name	SURP and G-patch domain containing 1
Gene symbol	SUGP1
Synonyms (NCBI Gene)	F23858RBPSF4
Chromosome	19
Chromosome location	19p13.11
Summary	SF4 is a member of the SURP family of splicing factors.[supplied by OMIM, Sep 2003]

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miRTarBase ID	miRNA	Experiments	Reference
MIRT023869	hsa-miR-1-3p	Proteomics;Microarray	18668037
MIRT049813	hsa-miR-92a-3p	CLASH	23622248
MIRT696466	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT696465	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT696464	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT696463	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT696462	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT696461	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT696460	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT696459	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT696458	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT696457	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT696456	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT696455	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT696454	hsa-miR-302e	HITS-CLIP	23313552
MIRT696453	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT696452	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT696451	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT696450	hsa-miR-520b	HITS-CLIP	23313552
MIRT696449	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT696448	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT696447	hsa-miR-520e	HITS-CLIP	23313552
MIRT696446	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT696445	hsa-miR-3973	HITS-CLIP	23313552
MIRT696444	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT696443	hsa-miR-520h	HITS-CLIP	23313552
MIRT696442	hsa-miR-212-5p	HITS-CLIP	23313552
MIRT696441	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT696440	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT696439	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT696438	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT696437	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT696436	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT696435	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT696434	hsa-miR-4707-3p	HITS-CLIP	23313552
MIRT696433	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT696432	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT696431	hsa-miR-6744-5p	HITS-CLIP	23313552
MIRT696430	hsa-miR-4757-5p	HITS-CLIP	23313552
MIRT696429	hsa-miR-6744-3p	HITS-CLIP	23313552
MIRT696428	hsa-miR-5187-5p	HITS-CLIP	23313552
MIRT696427	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT696426	hsa-miR-6728-5p	HITS-CLIP	23313552
MIRT696466	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT696465	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT696464	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT696463	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT696462	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT696461	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT696460	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT696459	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT696458	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT696457	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT696456	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT696455	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT696454	hsa-miR-302e	HITS-CLIP	23313552
MIRT696453	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT696452	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT696451	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT696450	hsa-miR-520b	HITS-CLIP	23313552
MIRT696449	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT696448	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT696447	hsa-miR-520e	HITS-CLIP	23313552
MIRT696446	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT696445	hsa-miR-3973	HITS-CLIP	23313552
MIRT696444	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT696443	hsa-miR-520h	HITS-CLIP	23313552
MIRT696442	hsa-miR-212-5p	HITS-CLIP	23313552
MIRT696441	hsa-miR-371b-5p	HITS-CLIP	23313552
MIRT696440	hsa-miR-373-5p	HITS-CLIP	23313552
MIRT696439	hsa-miR-616-5p	HITS-CLIP	23313552
MIRT696438	hsa-miR-371a-5p	HITS-CLIP	23313552
MIRT696437	hsa-miR-372-5p	HITS-CLIP	23313552
MIRT696436	hsa-miR-619-5p	HITS-CLIP	23313552
MIRT696435	hsa-miR-6506-5p	HITS-CLIP	23313552
MIRT696434	hsa-miR-4707-3p	HITS-CLIP	23313552
MIRT696433	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT696432	hsa-miR-5589-5p	HITS-CLIP	23313552
MIRT696431	hsa-miR-6744-5p	HITS-CLIP	23313552
MIRT696430	hsa-miR-4757-5p	HITS-CLIP	23313552
MIRT696429	hsa-miR-6744-3p	HITS-CLIP	23313552
MIRT696428	hsa-miR-5187-5p	HITS-CLIP	23313552
MIRT696427	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT696426	hsa-miR-6728-5p	HITS-CLIP	23313552
MIRT1402512	hsa-miR-191	CLIP-seq
MIRT1402513	hsa-miR-3177-3p	CLIP-seq
MIRT1402514	hsa-miR-3179	CLIP-seq
MIRT1402515	hsa-miR-3199	CLIP-seq
MIRT1402516	hsa-miR-3202	CLIP-seq
MIRT1402517	hsa-miR-3663-3p	CLIP-seq
MIRT1402518	hsa-miR-3936	CLIP-seq
MIRT1402519	hsa-miR-4504	CLIP-seq
MIRT1402520	hsa-miR-4636	CLIP-seq
MIRT1402521	hsa-miR-4651	CLIP-seq
MIRT1402522	hsa-miR-541	CLIP-seq
MIRT1402523	hsa-miR-549	CLIP-seq
MIRT1402524	hsa-miR-556-3p	CLIP-seq
MIRT1402525	hsa-miR-564	CLIP-seq
MIRT1402526	hsa-miR-602	CLIP-seq
MIRT1402527	hsa-miR-608	CLIP-seq
MIRT1402528	hsa-miR-654-5p	CLIP-seq

Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IBA
GO:0003723	Function	RNA binding	IEA
GO:0003729	Function	MRNA binding	IEA
GO:0005515	Function	Protein binding	IPI	21988832, 22365833, 35271311, 39251607
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IBA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005681	Component	Spliceosomal complex	IEA
GO:0006396	Process	RNA processing	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0008380	Process	RNA splicing	IEA

MIM	HGNC	e!Ensembl
607992	18643	ENSG00000105705

Q8IWZ8

Protein name

SURP and G-patch domain-containing protein 1 (RNA-binding protein RBP) (Splicing factor 4)

Protein function

Plays a role in pre-mRNA splicing.

PDB

8EJM , 8GXL , 8GXM

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01805	Surp	189 → 241	Surp module	Family
PF01805	Surp	264 → 316	Surp module	Family
PF01585	G-patch	562 → 607	G-patch domain	Family

Tissue specificity

TISSUE SPECIFICITY: Detected in adult testis and heart, and in adult and fetal brain, kidney and skeletal muscle. {ECO:0000269|PubMed:12594045}.

Sequence

MSLKMDNRDVAGKANRWFGVAPPKSGKMNMNILHQEELIAQKKREIEAKMEQKAKQNQVA
SPQPPHPGEITNAHNSSCISNKFANDGSFLQQFLKLQKAQTSTDAPTSAPSAPPSTPTPS
AGKRSLLISRRTGLGLASLPGPVKSYSHAKQLPVAHRPSVFQSPDEDEEEDYEQWLEIKV
SPPEGAETRKVIEKLARFVAEGGPELEKVAMEDYKDNPAFAFLHDKNSREFLYYRKKVAE
IRKEAQKSQAASQKVSPPEDEEVKNLAEKLARFIADGGPEVETIALQNNRENQAFSFLYE
PNSQGYKYYRQKLEEFRKAKASSTGSFTAPDPGLKRKSPPEALSGSLPPATTCPASSTPA
PTIIPAPAAPGKPASAATVKRKRKSRWGPEEDKVELPPAELVQRDVDASPSPLSVQDLKG
LGYEKGKPVGLVGVTELSDAQKKQLKEQQEMQQMYDMIMQHKRAMQDMQLLWEKAVQQHQ
HGYDSDEEVDSELGTWEHQLRRMEMDKTREWAEQLTKMGRGKHFIGDFLPPDELEKFMET
FKALKEGREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGSEGQGIKNPVNKGTTTVD
GAGFGIDRPAELSKEDDEYEAFRKRMMLAYRFRPNPLNNPRRPYY

Sequence length

645

Interactions

View interactions

	Reactome
			mRNA Splicing - Major Pathway

SUGP1 (SURP and G-patch domain containing 1)