Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	5771
Gene name	Protein tyrosine phosphatase non-receptor type 2
Gene symbol	PTPN2
Synonyms (NCBI Gene)	PTN2PTPTTC-PTPTC45TC48TCELLPTPTCPTP
Chromosome	18
Chromosome location	18p11.21
Summary	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that

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miRTarBase ID	miRNA	Experiments	Reference
MIRT054248	hsa-miR-210-3p	ChipLuciferase reporter assayQRTPCRWestern blot	23579275
MIRT450163	hsa-miR-1264	PAR-CLIP	22100165
MIRT450162	hsa-miR-520d-5p	PAR-CLIP	22100165
MIRT450161	hsa-miR-524-5p	PAR-CLIP	22100165
MIRT450163	hsa-miR-1264	HITS-CLIP	27418678
MIRT450163	hsa-miR-1264	HITS-CLIP	27418678
MIRT450163	hsa-miR-1264	PAR-CLIP	22100165
MIRT450162	hsa-miR-520d-5p	PAR-CLIP	22100165
MIRT450161	hsa-miR-524-5p	PAR-CLIP	22100165
MIRT1275415	hsa-miR-105	CLIP-seq
MIRT1275416	hsa-miR-1297	CLIP-seq
MIRT1275417	hsa-miR-1307	CLIP-seq
MIRT1275418	hsa-miR-205	CLIP-seq
MIRT1275419	hsa-miR-26a	CLIP-seq
MIRT1275420	hsa-miR-26b	CLIP-seq
MIRT1275421	hsa-miR-3145-3p	CLIP-seq
MIRT1275422	hsa-miR-3148	CLIP-seq
MIRT1275423	hsa-miR-3671	CLIP-seq
MIRT1275424	hsa-miR-4284	CLIP-seq
MIRT1275425	hsa-miR-4465	CLIP-seq
MIRT1275426	hsa-miR-4468	CLIP-seq
MIRT1275427	hsa-miR-4496	CLIP-seq
MIRT1275428	hsa-miR-4532	CLIP-seq
MIRT1275429	hsa-miR-4638-5p	CLIP-seq
MIRT1275430	hsa-miR-4760-3p	CLIP-seq
MIRT1275431	hsa-miR-4772-3p	CLIP-seq
MIRT1275432	hsa-miR-4775	CLIP-seq
MIRT1275433	hsa-miR-501-3p	CLIP-seq
MIRT1275434	hsa-miR-502-3p	CLIP-seq
MIRT1275435	hsa-miR-548ae	CLIP-seq
MIRT1275436	hsa-miR-548aj	CLIP-seq
MIRT1275437	hsa-miR-548am	CLIP-seq
MIRT1275438	hsa-miR-548x	CLIP-seq
MIRT1275439	hsa-miR-590-3p	CLIP-seq
MIRT1275440	hsa-miR-607	CLIP-seq
MIRT1275441	hsa-miR-651	CLIP-seq
MIRT1275442	hsa-miR-664	CLIP-seq
MIRT1275443	hsa-miR-767-5p	CLIP-seq
MIRT1275444	hsa-miR-155	CLIP-seq
MIRT1275445	hsa-miR-548l	CLIP-seq
MIRT1275446	hsa-miR-548n	CLIP-seq
MIRT1275447	hsa-miR-1180	CLIP-seq
MIRT1275448	hsa-miR-1203	CLIP-seq
MIRT1275449	hsa-miR-1294	CLIP-seq
MIRT1275450	hsa-miR-1827	CLIP-seq
MIRT1275451	hsa-miR-216a	CLIP-seq
MIRT1275452	hsa-miR-216b	CLIP-seq
MIRT1275453	hsa-miR-30a	CLIP-seq
MIRT1275454	hsa-miR-30b	CLIP-seq
MIRT1275455	hsa-miR-30c	CLIP-seq
MIRT1275456	hsa-miR-30d	CLIP-seq
MIRT1275457	hsa-miR-30e	CLIP-seq
MIRT1275458	hsa-miR-331-3p	CLIP-seq
MIRT1275459	hsa-miR-338-5p	CLIP-seq
MIRT1275460	hsa-miR-34a	CLIP-seq
MIRT1275461	hsa-miR-34c-5p	CLIP-seq
MIRT1275462	hsa-miR-3907	CLIP-seq
MIRT1275463	hsa-miR-4308	CLIP-seq
MIRT1275464	hsa-miR-431	CLIP-seq
MIRT1275465	hsa-miR-4316	CLIP-seq
MIRT1275466	hsa-miR-4417	CLIP-seq
MIRT1275467	hsa-miR-4481	CLIP-seq
MIRT1275468	hsa-miR-4495	CLIP-seq
MIRT1275469	hsa-miR-449a	CLIP-seq
MIRT1275470	hsa-miR-449b	CLIP-seq
MIRT1275471	hsa-miR-4664-3p	CLIP-seq
MIRT1275472	hsa-miR-4677-3p	CLIP-seq
MIRT1275473	hsa-miR-4698	CLIP-seq
MIRT1275474	hsa-miR-4735-5p	CLIP-seq
MIRT1275475	hsa-miR-4745-5p	CLIP-seq
MIRT1275476	hsa-miR-4764-5p	CLIP-seq
MIRT1275477	hsa-miR-495	CLIP-seq
MIRT1275478	hsa-miR-507	CLIP-seq
MIRT1275479	hsa-miR-518d-5p	CLIP-seq
MIRT1275480	hsa-miR-519b-5p	CLIP-seq
MIRT1275481	hsa-miR-519c-5p	CLIP-seq
MIRT1275482	hsa-miR-520c-5p	CLIP-seq
MIRT1275483	hsa-miR-526a	CLIP-seq
MIRT1275484	hsa-miR-548a-5p	CLIP-seq
MIRT1275485	hsa-miR-548ab	CLIP-seq
MIRT1275486	hsa-miR-548ac	CLIP-seq
MIRT1275435	hsa-miR-548ae	CLIP-seq
MIRT1275436	hsa-miR-548aj	CLIP-seq
MIRT1275487	hsa-miR-548ak	CLIP-seq
MIRT1275437	hsa-miR-548am	CLIP-seq
MIRT1275488	hsa-miR-548b-5p	CLIP-seq
MIRT1275489	hsa-miR-548c-5p	CLIP-seq
MIRT1275490	hsa-miR-548d-3p	CLIP-seq
MIRT1275491	hsa-miR-548d-5p	CLIP-seq
MIRT1275492	hsa-miR-548h	CLIP-seq
MIRT1275493	hsa-miR-548i	CLIP-seq
MIRT1275494	hsa-miR-548j	CLIP-seq
MIRT1275495	hsa-miR-548w	CLIP-seq
MIRT1275438	hsa-miR-548x	CLIP-seq
MIRT1275496	hsa-miR-548y	CLIP-seq
MIRT1275497	hsa-miR-548z	CLIP-seq
MIRT1275498	hsa-miR-557	CLIP-seq
MIRT1275499	hsa-miR-559	CLIP-seq
MIRT1275500	hsa-miR-561	CLIP-seq
MIRT1275501	hsa-miR-578	CLIP-seq
MIRT1275502	hsa-miR-643	CLIP-seq
MIRT2081102	hsa-miR-192	CLIP-seq
MIRT2081103	hsa-miR-215	CLIP-seq
MIRT2081104	hsa-miR-223	CLIP-seq
MIRT2081105	hsa-miR-33a	CLIP-seq
MIRT2081106	hsa-miR-33b	CLIP-seq
MIRT2081107	hsa-miR-3923	CLIP-seq
MIRT2081108	hsa-miR-4454	CLIP-seq
MIRT2081109	hsa-miR-4697-3p	CLIP-seq
MIRT2081110	hsa-miR-4707-3p	CLIP-seq
MIRT2081111	hsa-miR-4731-5p	CLIP-seq
MIRT2081112	hsa-miR-935	CLIP-seq
MIRT1275449	hsa-miR-1294	CLIP-seq
MIRT2306989	hsa-miR-138	CLIP-seq
MIRT1275450	hsa-miR-1827	CLIP-seq
MIRT2306990	hsa-miR-22	CLIP-seq
MIRT2306991	hsa-miR-2276	CLIP-seq
MIRT2306992	hsa-miR-298	CLIP-seq
MIRT1275453	hsa-miR-30a	CLIP-seq
MIRT1275454	hsa-miR-30b	CLIP-seq
MIRT1275455	hsa-miR-30c	CLIP-seq
MIRT1275456	hsa-miR-30d	CLIP-seq
MIRT1275457	hsa-miR-30e	CLIP-seq
MIRT2306993	hsa-miR-3158-5p	CLIP-seq
MIRT2306994	hsa-miR-3182	CLIP-seq
MIRT1275462	hsa-miR-3907	CLIP-seq
MIRT2306995	hsa-miR-4282	CLIP-seq
MIRT1275465	hsa-miR-4316	CLIP-seq
MIRT2306996	hsa-miR-4456	CLIP-seq
MIRT1275472	hsa-miR-4677-3p	CLIP-seq
MIRT1275431	hsa-miR-4772-3p	CLIP-seq
MIRT1275477	hsa-miR-495	CLIP-seq
MIRT2306997	hsa-miR-518a-5p	CLIP-seq
MIRT2306998	hsa-miR-527	CLIP-seq
MIRT2306999	hsa-miR-541	CLIP-seq
MIRT2307000	hsa-miR-544	CLIP-seq
MIRT2307001	hsa-miR-548m	CLIP-seq
MIRT1275500	hsa-miR-561	CLIP-seq
MIRT2307002	hsa-miR-654-5p	CLIP-seq
MIRT2393224	hsa-miR-106a	CLIP-seq
MIRT2393225	hsa-miR-106b	CLIP-seq
MIRT2393226	hsa-miR-125a-3p	CLIP-seq
MIRT2393227	hsa-miR-150	CLIP-seq
MIRT2393228	hsa-miR-17	CLIP-seq
MIRT2393229	hsa-miR-1913	CLIP-seq
MIRT2393230	hsa-miR-20a	CLIP-seq
MIRT2393231	hsa-miR-20b	CLIP-seq
MIRT2393232	hsa-miR-302a	CLIP-seq
MIRT2393233	hsa-miR-302b	CLIP-seq
MIRT2393234	hsa-miR-302c	CLIP-seq
MIRT2393235	hsa-miR-302d	CLIP-seq
MIRT2393236	hsa-miR-302e	CLIP-seq
MIRT2393237	hsa-miR-3157-5p	CLIP-seq
MIRT2393238	hsa-miR-324-3p	CLIP-seq
MIRT2393239	hsa-miR-372	CLIP-seq
MIRT2393240	hsa-miR-373	CLIP-seq
MIRT2393241	hsa-miR-3934	CLIP-seq
MIRT2393242	hsa-miR-4438	CLIP-seq
MIRT2081111	hsa-miR-4731-5p	CLIP-seq
MIRT2393243	hsa-miR-5095	CLIP-seq
MIRT2393244	hsa-miR-512-3p	CLIP-seq
MIRT2393245	hsa-miR-519d	CLIP-seq
MIRT2393246	hsa-miR-520a-3p	CLIP-seq
MIRT2393247	hsa-miR-520b	CLIP-seq
MIRT2393248	hsa-miR-520c-3p	CLIP-seq
MIRT2393249	hsa-miR-520d-3p	CLIP-seq
MIRT2393250	hsa-miR-520e	CLIP-seq
MIRT2393251	hsa-miR-520g	CLIP-seq
MIRT2393252	hsa-miR-520h	CLIP-seq
MIRT2393253	hsa-miR-764	CLIP-seq
MIRT2393254	hsa-miR-93	CLIP-seq
MIRT2457430	hsa-miR-122	CLIP-seq
MIRT2457431	hsa-miR-1249	CLIP-seq
MIRT2457432	hsa-miR-1273f	CLIP-seq
MIRT2457433	hsa-miR-1289	CLIP-seq
MIRT1275416	hsa-miR-1297	CLIP-seq
MIRT1275417	hsa-miR-1307	CLIP-seq
MIRT2457434	hsa-miR-143	CLIP-seq
MIRT2457435	hsa-miR-1976	CLIP-seq
MIRT1275419	hsa-miR-26a	CLIP-seq
MIRT1275420	hsa-miR-26b	CLIP-seq
MIRT2457436	hsa-miR-3064-5p	CLIP-seq
MIRT2457437	hsa-miR-3125	CLIP-seq
MIRT2457438	hsa-miR-3198	CLIP-seq
MIRT2457439	hsa-miR-335	CLIP-seq
MIRT2081105	hsa-miR-33a	CLIP-seq
MIRT2081106	hsa-miR-33b	CLIP-seq
MIRT2457440	hsa-miR-3914	CLIP-seq
MIRT2457441	hsa-miR-3916	CLIP-seq
MIRT2457442	hsa-miR-3928	CLIP-seq
MIRT2457443	hsa-miR-411	CLIP-seq
MIRT2457444	hsa-miR-4279	CLIP-seq
MIRT1275424	hsa-miR-4284	CLIP-seq
MIRT2457445	hsa-miR-4294	CLIP-seq
MIRT2457446	hsa-miR-4309	CLIP-seq
MIRT1275425	hsa-miR-4465	CLIP-seq
MIRT2457447	hsa-miR-4505	CLIP-seq
MIRT2457448	hsa-miR-450b-5p	CLIP-seq
MIRT1275428	hsa-miR-4532	CLIP-seq
MIRT2457449	hsa-miR-4534	CLIP-seq
MIRT1275429	hsa-miR-4638-5p	CLIP-seq
MIRT2457450	hsa-miR-4708-5p	CLIP-seq
MIRT2457451	hsa-miR-4722-3p	CLIP-seq
MIRT1275474	hsa-miR-4735-5p	CLIP-seq
MIRT2457452	hsa-miR-4770	CLIP-seq
MIRT1275431	hsa-miR-4772-3p	CLIP-seq
MIRT1275432	hsa-miR-4775	CLIP-seq
MIRT1275478	hsa-miR-507	CLIP-seq
MIRT1275498	hsa-miR-557	CLIP-seq
MIRT1275439	hsa-miR-590-3p	CLIP-seq
MIRT2457453	hsa-miR-720	CLIP-seq
MIRT2604582	hsa-miR-101	CLIP-seq
MIRT2604583	hsa-miR-144	CLIP-seq
MIRT2604584	hsa-miR-3163	CLIP-seq
MIRT1275460	hsa-miR-34a	CLIP-seq
MIRT1275461	hsa-miR-34c-5p	CLIP-seq
MIRT1275469	hsa-miR-449a	CLIP-seq
MIRT1275470	hsa-miR-449b	CLIP-seq
MIRT2604585	hsa-miR-548c-3p	CLIP-seq
MIRT2604582	hsa-miR-101	CLIP-seq
MIRT2604583	hsa-miR-144	CLIP-seq
MIRT2604584	hsa-miR-3163	CLIP-seq
MIRT1275460	hsa-miR-34a	CLIP-seq
MIRT1275461	hsa-miR-34c-5p	CLIP-seq
MIRT1275469	hsa-miR-449a	CLIP-seq
MIRT1275470	hsa-miR-449b	CLIP-seq
MIRT2604585	hsa-miR-548c-3p	CLIP-seq

Show/Hide all (93)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0004721	Function	Phosphoprotein phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	EXP	12138178
GO:0004725	Function	Protein tyrosine phosphatase activity	IDA	12138178, 12612081, 17210636, 23006999
GO:0004725	Function	Protein tyrosine phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	IMP	11909529, 14966296
GO:0004725	Function	Protein tyrosine phosphatase activity	TAS
GO:0004726	Function	Non-membrane spanning protein tyrosine phosphatase activity	IBA
GO:0005178	Function	Integrin binding	IPI	15592458
GO:0005515	Function	Protein binding	IPI	12359225, 12907755, 15696169, 16595549, 19273555, 22080863, 28514442, 33961781, 35013194
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	7593185, 12612081
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA	7593185, 10940933
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IDA	23006999
GO:0005793	Component	Endoplasmic reticulum-Golgi intermediate compartment	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	15592458
GO:0005886	Component	Plasma membrane	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IMP	15592458
GO:0008286	Process	Insulin receptor signaling pathway	IEA
GO:0008286	Process	Insulin receptor signaling pathway	ISS
GO:0010804	Process	Negative regulation of tumor necrosis factor-mediated signaling pathway	IEA
GO:0010804	Process	Negative regulation of tumor necrosis factor-mediated signaling pathway	ISS
GO:0010888	Process	Negative regulation of lipid storage	IEA
GO:0010888	Process	Negative regulation of lipid storage	ISS
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0019901	Function	Protein kinase binding	IBA
GO:0019901	Function	Protein kinase binding	IPI	11909529, 15696169
GO:0019905	Function	Syntaxin binding	IPI	23006999
GO:0030183	Process	B cell differentiation	IEA
GO:0030183	Process	B cell differentiation	ISS
GO:0030217	Process	T cell differentiation	IEA
GO:0030217	Process	T cell differentiation	ISS
GO:0030218	Process	Erythrocyte differentiation	IEA
GO:0030218	Process	Erythrocyte differentiation	ISS
GO:0030971	Function	Receptor tyrosine kinase binding	IEA
GO:0030971	Function	Receptor tyrosine kinase binding	IPI	18819921
GO:0031904	Component	Endosome lumen	IEA
GO:0035335	Process	Peptidyl-tyrosine dephosphorylation	IMP	11909529, 14966296
GO:0038020	Process	Insulin receptor recycling	IEA
GO:0042059	Process	Negative regulation of epidermal growth factor receptor signaling pathway	IMP	15592458
GO:0042532	Process	Negative regulation of tyrosine phosphorylation of STAT protein	IDA	12359225
GO:0042593	Process	Glucose homeostasis	IEA
GO:0042593	Process	Glucose homeostasis	ISS
GO:0045650	Process	Negative regulation of macrophage differentiation	IEA
GO:0045650	Process	Negative regulation of macrophage differentiation	ISS
GO:0045722	Process	Positive regulation of gluconeogenesis	IEA
GO:0045722	Process	Positive regulation of gluconeogenesis	ISS
GO:0046426	Process	Negative regulation of receptor signaling pathway via JAK-STAT	IBA
GO:0046627	Process	Negative regulation of insulin receptor signaling pathway	IEA
GO:0046627	Process	Negative regulation of insulin receptor signaling pathway	ISS
GO:0050728	Process	Negative regulation of inflammatory response	IEA
GO:0050728	Process	Negative regulation of inflammatory response	ISS
GO:0050860	Process	Negative regulation of T cell receptor signaling pathway	IEA
GO:0050860	Process	Negative regulation of T cell receptor signaling pathway	ISS
GO:0050922	Process	Negative regulation of chemotaxis	IEA
GO:0050922	Process	Negative regulation of chemotaxis	ISS
GO:0060334	Process	Regulation of type II interferon-mediated signaling pathway	TAS
GO:0060336	Process	Negative regulation of type II interferon-mediated signaling pathway	IDA	12138178
GO:0060336	Process	Negative regulation of type II interferon-mediated signaling pathway	IEA
GO:0060336	Process	Negative regulation of type II interferon-mediated signaling pathway	IMP	12138178
GO:0060336	Process	Negative regulation of type II interferon-mediated signaling pathway	ISS
GO:0060338	Process	Regulation of type I interferon-mediated signaling pathway	IEA
GO:0060339	Process	Negative regulation of type I interferon-mediated signaling pathway	IEA
GO:0060339	Process	Negative regulation of type I interferon-mediated signaling pathway	IMP	11909529
GO:0070104	Process	Negative regulation of interleukin-6-mediated signaling pathway	IEA
GO:0070104	Process	Negative regulation of interleukin-6-mediated signaling pathway	IMP	12359225
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IBA
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IEA
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	ISS
GO:0097677	Function	STAT family protein binding	IEA
GO:1902202	Process	Regulation of hepatocyte growth factor receptor signaling pathway	IEA
GO:1902202	Process	Regulation of hepatocyte growth factor receptor signaling pathway	IMP	18819921
GO:1902206	Process	Negative regulation of interleukin-2-mediated signaling pathway	IEA
GO:1902206	Process	Negative regulation of interleukin-2-mediated signaling pathway	IMP	11909529
GO:1902215	Process	Negative regulation of interleukin-4-mediated signaling pathway	IEA
GO:1902215	Process	Negative regulation of interleukin-4-mediated signaling pathway	IMP	17210636
GO:1902227	Process	Negative regulation of macrophage colony-stimulating factor signaling pathway	IEA
GO:1902227	Process	Negative regulation of macrophage colony-stimulating factor signaling pathway	ISS
GO:1902233	Process	Negative regulation of positive thymic T cell selection	IEA
GO:1902233	Process	Negative regulation of positive thymic T cell selection	ISS
GO:1902237	Process	Positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	IEA
GO:1903899	Process	Positive regulation of PERK-mediated unfolded protein response	IEA
GO:2000587	Process	Negative regulation of platelet-derived growth factor receptor-beta signaling pathway	IEA
GO:2000587	Process	Negative regulation of platelet-derived growth factor receptor-beta signaling pathway	ISS

MIM	HGNC	e!Ensembl
176887	9650	ENSG00000175354

P17706

Protein name

Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP)

Protein function

Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, ST

PDB

1L8K , 6ZZ4 , 7F5N , 7F5O , 7UAD , 8U0H , 8UH6 , 9C54 , 9C55 , 9C56

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00102	Y_phosphatase	42 → 274	Protein-tyrosine phosphatase	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. Isoform 2 is probably the major isoform. Isoform 1 is expressed in T-cells and in placenta. {ECO:0000269|PubMed:1731319, ECO:0000269|PubMed:2546150}.

Sequence

MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW
PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD
DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA
FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
TAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL

Sequence length

415

Interactions

View interactions

	KEGG		Reactome
	JAK-STAT signaling pathway		Negative regulation of MET activity Regulation of IFNG signaling Interleukin-37 signaling

PTPN2 (protein tyrosine phosphatase non-receptor type 2)