DENND1A (DENN domain containing 1A)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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57706 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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DENN domain containing 1A |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DENND1A |
Synonyms (NCBI Gene)
Gene synonyms aliases
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FAM31A, KIAA1608 |
Chromosome
Chromosome number
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9 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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9q33.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | Q8TEH3 | ||||||||||||||||||||
Protein name | DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn) (Protein FAM31A) | ||||||||||||||||||||
Protein function | Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endo | ||||||||||||||||||||
PDB | 6EKK | ||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 1009 | ||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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