Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	57697
Gene name Gene Name - the full gene name approved by the HGNC.	FA complementation group M
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FANCM
Synonyms (NCBI Gene) Gene synonyms aliases	FAAP250, KIAA1596, POF15, SPGF28
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q21.2
Summary Summary of gene provided in NCBI Entrez Gene.	The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FAN

Show/Hide all(19)

SNP ID	Visualize variation	Clinical significance	Consequence
rs61753893	A>G	Conflicting-interpretations-of-pathogenicity, benign	Non coding transcript variant, genic upstream transcript variant, coding sequence variant, missense variant
rs142864437	A>C,G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Synonymous variant, genic downstream transcript variant, coding sequence variant, non coding transcript variant, missense variant
rs144215747	C>G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, missense variant, non coding transcript variant
rs144567652	C>A,T	Uncertain-significance, pathogenic	Stop gained, synonymous variant, genic downstream transcript variant, coding sequence variant, non coding transcript variant, intron variant
rs146897650	A>G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, non coding transcript variant, downstream transcript variant, missense variant
rs147021911	C>T	Pathogenic, likely-pathogenic, risk-factor	Stop gained, genic downstream transcript variant, coding sequence variant, non coding transcript variant, downstream transcript variant
rs200173413	A>C,G	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, non coding transcript variant, missense variant, genic downstream transcript variant
rs762570903	CTCT>-,CT,CTCTCT	Pathogenic	Genic downstream transcript variant, stop gained, frameshift variant, non coding transcript variant, coding sequence variant
rs768006618	AAAA>-,AAAAA	Likely-pathogenic, uncertain-significance	Frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs797045116	->A	Likely-pathogenic, pathogenic	Coding sequence variant, non coding transcript variant, frameshift variant, genic upstream transcript variant
rs1375421660	AT>-	Likely-pathogenic	Frameshift variant, non coding transcript variant, coding sequence variant, genic downstream transcript variant
rs1555361990	G>-	Likely-pathogenic	Genic upstream transcript variant, non coding transcript variant, coding sequence variant, frameshift variant
rs1555363275	CAGAGAAGCCTTC>-	Pathogenic	Genic upstream transcript variant, non coding transcript variant, coding sequence variant, frameshift variant
rs1555365959	A>G	Pathogenic	Genic downstream transcript variant, intron variant
rs1566761441	G>T	Pathogenic	Genic downstream transcript variant, non coding transcript variant, stop gained, coding sequence variant
rs1566764032	G>T	Pathogenic	Genic downstream transcript variant, non coding transcript variant, stop gained, coding sequence variant
rs1566766719	->G	Pathogenic	Genic downstream transcript variant, frameshift variant, non coding transcript variant, coding sequence variant
rs1566775496	C>G	Pathogenic	Genic downstream transcript variant, non coding transcript variant, stop gained, coding sequence variant
rs1594810654	TTTT>CAACTTTCCTCATTACTTGACTCAACATTACTTGACTCAACTCAACTC	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant, inframe indel, non coding transcript variant

Show/Hide all(153)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016474	hsa-miR-193b-3p	Microarray	20304954
MIRT026567	hsa-miR-192-5p	Microarray	19074876
MIRT695957	hsa-miR-122-3p	HITS-CLIP	23313552
MIRT695956	hsa-miR-1247-3p	HITS-CLIP	23313552
MIRT695955	hsa-miR-4532	HITS-CLIP	23313552
MIRT695954	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT695953	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT695952	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT695951	hsa-miR-1976	HITS-CLIP	23313552
MIRT695949	hsa-miR-4268	HITS-CLIP	23313552
MIRT695950	hsa-miR-4448	HITS-CLIP	23313552
MIRT695948	hsa-miR-6772-3p	HITS-CLIP	23313552
MIRT551967	hsa-miR-4803	PAR-CLIP	21572407
MIRT070052	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT070051	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT070050	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT070055	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT070060	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT070064	hsa-miR-3908	PAR-CLIP	21572407
MIRT551966	hsa-miR-4795-5p	PAR-CLIP	21572407
MIRT070058	hsa-miR-889-3p	PAR-CLIP	21572407
MIRT070062	hsa-miR-3616-5p	PAR-CLIP	21572407
MIRT070054	hsa-miR-573	PAR-CLIP	21572407
MIRT695957	hsa-miR-122-3p	HITS-CLIP	23313552
MIRT695956	hsa-miR-1247-3p	HITS-CLIP	23313552
MIRT695955	hsa-miR-4532	HITS-CLIP	23313552
MIRT695954	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT695953	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT695952	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT695951	hsa-miR-1976	HITS-CLIP	23313552
MIRT695949	hsa-miR-4268	HITS-CLIP	23313552
MIRT695950	hsa-miR-4448	HITS-CLIP	23313552
MIRT695948	hsa-miR-6772-3p	HITS-CLIP	23313552
MIRT551967	hsa-miR-4803	PAR-CLIP	21572407
MIRT070052	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT070051	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT070050	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT070055	hsa-miR-580-5p	PAR-CLIP	21572407
MIRT070060	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT070064	hsa-miR-3908	PAR-CLIP	21572407
MIRT551966	hsa-miR-4795-5p	PAR-CLIP	21572407
MIRT070058	hsa-miR-889-3p	PAR-CLIP	21572407
MIRT070062	hsa-miR-3616-5p	PAR-CLIP	21572407
MIRT070054	hsa-miR-573	PAR-CLIP	21572407
MIRT989199	hsa-miR-146a	CLIP-seq
MIRT989200	hsa-miR-146b-5p	CLIP-seq
MIRT989201	hsa-miR-21	CLIP-seq
MIRT989202	hsa-miR-2110	CLIP-seq
MIRT989203	hsa-miR-2467-3p	CLIP-seq
MIRT989204	hsa-miR-3074-3p	CLIP-seq
MIRT989205	hsa-miR-31	CLIP-seq
MIRT989206	hsa-miR-3125	CLIP-seq
MIRT989207	hsa-miR-3144-5p	CLIP-seq
MIRT989208	hsa-miR-3150a-3p	CLIP-seq
MIRT989209	hsa-miR-3158-5p	CLIP-seq
MIRT989210	hsa-miR-3163	CLIP-seq
MIRT989211	hsa-miR-3191	CLIP-seq
MIRT989212	hsa-miR-340	CLIP-seq
MIRT989213	hsa-miR-34a	CLIP-seq
MIRT989214	hsa-miR-34c-5p	CLIP-seq
MIRT989215	hsa-miR-361-5p	CLIP-seq
MIRT989216	hsa-miR-3647-5p	CLIP-seq
MIRT989217	hsa-miR-3678-3p	CLIP-seq
MIRT989218	hsa-miR-3692	CLIP-seq
MIRT989219	hsa-miR-3916	CLIP-seq
MIRT989220	hsa-miR-3925-5p	CLIP-seq
MIRT989221	hsa-miR-4418	CLIP-seq
MIRT989222	hsa-miR-449a	CLIP-seq
MIRT989223	hsa-miR-449b	CLIP-seq
MIRT989224	hsa-miR-4652-5p	CLIP-seq
MIRT989225	hsa-miR-509-3-5p	CLIP-seq
MIRT989226	hsa-miR-509-5p	CLIP-seq
MIRT989227	hsa-miR-519a	CLIP-seq
MIRT989228	hsa-miR-548aa	CLIP-seq
MIRT989229	hsa-miR-590-5p	CLIP-seq
MIRT989230	hsa-miR-659	CLIP-seq
MIRT989231	hsa-miR-759	CLIP-seq
MIRT989232	hsa-miR-889	CLIP-seq
MIRT1993111	hsa-miR-101	CLIP-seq
MIRT1993112	hsa-miR-128	CLIP-seq
MIRT1993113	hsa-miR-1910	CLIP-seq
MIRT1993114	hsa-miR-27a	CLIP-seq
MIRT1993115	hsa-miR-27b	CLIP-seq
MIRT1993116	hsa-miR-3122	CLIP-seq
MIRT989208	hsa-miR-3150a-3p	CLIP-seq
MIRT1993117	hsa-miR-3153	CLIP-seq
MIRT1993118	hsa-miR-3175	CLIP-seq
MIRT1993119	hsa-miR-3652	CLIP-seq
MIRT1993120	hsa-miR-3913-5p	CLIP-seq
MIRT1993121	hsa-miR-4430	CLIP-seq
MIRT1993122	hsa-miR-4471	CLIP-seq
MIRT1993123	hsa-miR-4505	CLIP-seq
MIRT1993124	hsa-miR-4667-5p	CLIP-seq
MIRT1993125	hsa-miR-4668-5p	CLIP-seq
MIRT1993126	hsa-miR-4700-5p	CLIP-seq
MIRT1993127	hsa-miR-4709-5p	CLIP-seq
MIRT1993128	hsa-miR-4731-5p	CLIP-seq
MIRT1993129	hsa-miR-4775	CLIP-seq
MIRT1993130	hsa-miR-590-3p	CLIP-seq
MIRT1993131	hsa-miR-939	CLIP-seq
MIRT2227029	hsa-miR-1275	CLIP-seq
MIRT1993112	hsa-miR-128	CLIP-seq
MIRT1993113	hsa-miR-1910	CLIP-seq
MIRT989202	hsa-miR-2110	CLIP-seq
MIRT1993114	hsa-miR-27a	CLIP-seq
MIRT1993115	hsa-miR-27b	CLIP-seq
MIRT989204	hsa-miR-3074-3p	CLIP-seq
MIRT989207	hsa-miR-3144-5p	CLIP-seq
MIRT989208	hsa-miR-3150a-3p	CLIP-seq
MIRT1993118	hsa-miR-3175	CLIP-seq
MIRT989211	hsa-miR-3191	CLIP-seq
MIRT989215	hsa-miR-361-5p	CLIP-seq
MIRT1993119	hsa-miR-3652	CLIP-seq
MIRT1993121	hsa-miR-4430	CLIP-seq
MIRT1993122	hsa-miR-4471	CLIP-seq
MIRT1993123	hsa-miR-4505	CLIP-seq
MIRT2227030	hsa-miR-4525	CLIP-seq
MIRT989224	hsa-miR-4652-5p	CLIP-seq
MIRT2227031	hsa-miR-4665-5p	CLIP-seq
MIRT1993124	hsa-miR-4667-5p	CLIP-seq
MIRT1993126	hsa-miR-4700-5p	CLIP-seq
MIRT2227032	hsa-miR-4723-5p	CLIP-seq
MIRT1993128	hsa-miR-4731-5p	CLIP-seq
MIRT2227033	hsa-miR-4773	CLIP-seq
MIRT2227034	hsa-miR-625	CLIP-seq
MIRT989230	hsa-miR-659	CLIP-seq
MIRT1993131	hsa-miR-939	CLIP-seq
MIRT1993112	hsa-miR-128	CLIP-seq
MIRT1993113	hsa-miR-1910	CLIP-seq
MIRT1993114	hsa-miR-27a	CLIP-seq
MIRT1993115	hsa-miR-27b	CLIP-seq
MIRT989208	hsa-miR-3150a-3p	CLIP-seq
MIRT1993118	hsa-miR-3175	CLIP-seq
MIRT1993119	hsa-miR-3652	CLIP-seq
MIRT1993121	hsa-miR-4430	CLIP-seq
MIRT1993123	hsa-miR-4505	CLIP-seq
MIRT1993124	hsa-miR-4667-5p	CLIP-seq
MIRT1993126	hsa-miR-4700-5p	CLIP-seq
MIRT1993128	hsa-miR-4731-5p	CLIP-seq
MIRT1993131	hsa-miR-939	CLIP-seq
MIRT1993112	hsa-miR-128	CLIP-seq
MIRT1993113	hsa-miR-1910	CLIP-seq
MIRT1993114	hsa-miR-27a	CLIP-seq
MIRT1993115	hsa-miR-27b	CLIP-seq
MIRT989208	hsa-miR-3150a-3p	CLIP-seq
MIRT1993118	hsa-miR-3175	CLIP-seq
MIRT1993119	hsa-miR-3652	CLIP-seq
MIRT1993121	hsa-miR-4430	CLIP-seq
MIRT1993123	hsa-miR-4505	CLIP-seq
MIRT1993124	hsa-miR-4667-5p	CLIP-seq
MIRT1993126	hsa-miR-4700-5p	CLIP-seq
MIRT1993128	hsa-miR-4731-5p	CLIP-seq
MIRT1993131	hsa-miR-939	CLIP-seq

Show/Hide all(32)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000400	Function	Four-way junction DNA binding	IBA
GO:0000712	Process	Resolution of meiotic recombination intermediates	IMP	20347428
GO:0000785	Component	Chromatin	IDA	20347429
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003682	Function	Chromatin binding	IDA	20347429
GO:0003724	Function	RNA helicase activity	IEA
GO:0004386	Function	Helicase activity	IEA
GO:0004518	Function	Nuclease activity	IEA
GO:0005515	Function	Protein binding	IPI	17289582, 20347429, 23932590, 25416956, 32296183, 32769987, 33961781
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005829	Component	Cytosol	TAS
GO:0006281	Process	DNA repair	IEA
GO:0006974	Process	DNA damage response	IEA
GO:0009378	Function	Four-way junction helicase activity	IBA
GO:0016787	Function	Hydrolase activity	IEA
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0031297	Process	Replication fork processing	IMP	20347428
GO:0035825	Process	Homologous recombination	IEA
GO:0036297	Process	Interstrand cross-link repair	IBA
GO:0036297	Process	Interstrand cross-link repair	IDA	20347429
GO:0043138	Function	3'-5' DNA helicase activity	IBA
GO:0043138	Function	3'-5' DNA helicase activity	IEA
GO:0043240	Component	Fanconi anaemia nuclear complex	IDA	20347428, 20347429
GO:0045003	Process	Double-strand break repair via synthesis-dependent strand annealing	IBA
GO:0071821	Component	FANCM-MHF complex	IDA	20347428
GO:0071821	Component	FANCM-MHF complex	IPI	20347429
GO:1902527	Process	Positive regulation of protein monoubiquitination	IMP	29231814

MIM	HGNC	e!Ensembl
609644	23168	ENSG00000187790

Protein

UniProt ID

Q8IYD8

Protein name

Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)

Protein function

DNA-dependent ATPase component of the Fanconi anemia (FA) core complex (PubMed:16116422). Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resista

PDB

4BXO , 4DAY , 4DRB , 4E45 , 4M6W

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04851	ResIII	88 → 250	Type III restriction enzyme, res subunit	Family
PF00271	Helicase_C	456 → 581	Helicase conserved C-terminal domain	Family
PF16783	FANCM-MHF_bd	675 → 790	FANCM to MHF binding domain	Domain
PF02732	ERCC4	1826 → 1948	ERCC4 domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in germ cells of fetal and adult ovaries. In fetal ovaries, it is present in oogonia but expression is stronger in pachytene stage oocytes. Expressed in oocytes arrested at the diplotene stage of prophase I during the last tr

Sequence

MSGRQRTLFQTWGSSISRSSGTPGCSSGTERPQSPGSSKAPLPAAAEAQLESDDDVLLVA
AYEAERQLCLENGGFCTSAGALWIYPTNCPVRDYQLHISRAALFCNTLVCLPTGLGKTFI
AAVVMYNFYRWFPSGKVVFMAPTKPLVTQQIEACYQVMGIPQSHMAEMTGSTQASTRKEI
WCSKRVLFLTPQVMVNDLSRGACPAAEIKCLVIDEAHKALGNYAYCQVVRELVKYTNHFR
ILALSATPGSDIKAVQQVITNLLIGQIELRSEDSPDILTYSHERKVEKLIVPLGEELAAI
QKTYIQILESFARSLIQRNVLMRRDIPNLTKYQIILARDQFRKNPSPNIVGIQQGIIEGE
FAICISLYHGYELLQQMGMRSLYFFLCGIMDGTKGMTRSKNELGRNEDFMKLYNHLECMF
ARTRSTSANGISAIQQGDKNKKFVYSHPKLKKLEEVVIEHFKSWNAENTTEKKRDETRVM
IFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTL
VSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQ
SQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKS
SIFSYRDGMRQSSLKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKP
AQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRHEEGECSYELE
VESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIV
KQTHIKPTKIVSLKKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRT
SDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFNDEKSVSSNLF
LPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENL
LFLPCAEHLRSDKCTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSL
CDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQDESLLLFEDV
NTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANS
FKSRDQRGVQEEKVKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLY
GRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEEL
LSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNST
FDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPED
QKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNARRGIKVPKR
QSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSE
MRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSE
EEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNV
NDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKD
TISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRP
HLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNR
MVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDS
LLTTLIGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIP
NISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVFDIQMLPNDLN
QDRLKSDI

Sequence length

2048

Interactions

View interactions

	KEGG		Reactome
	Fanconi anemia pathway		Fanconi Anemia Pathway

Show/Hide Causal Diseases (7)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Fanconi Anemia	fanconi anemia, Fanconi anemia complementation group A	rs1566766719, rs1383262366, rs768006618, rs765686151, rs147021911, rs1888605629, rs778744393, rs368728266, rs1888681090, rs1594810556, rs1888718087, rs754297345, rs757391108, rs1166587869, rs1566790465 View all (16 more)	N/A
Premature Ovarian Failure	premature ovarian failure 15	rs144567652, rs147021911	N/A
Spermatogenic Failure	spermatogenic failure 28	rs768006618, rs1555365959, rs368728266, rs1555363275, rs797045116, rs144567652	N/A
Azoospermia	azoospermia	rs144567652	N/A
Hereditary nonpolyposis colorectal cancer	hereditary nonpolyposis colorectal carcinoma	rs144567652	N/A
Male infertility	male infertility with azoospermia or oligozoospermia due to single gene mutation	rs797045116	N/A
Retinoblastoma	retinoblastoma	rs1375421660	N/A

Show/Hide Unknown Diseases (5)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Aplastic anemia	aplastic anemia	N/A	N/A	ClinVar
Breast Cancer	breast cancer	N/A	N/A	GenCC
Glioblastoma	Glioblastoma	N/A	N/A	GWAS
Hepatoblastoma	hepatoblastoma	N/A	N/A	ClinVar
hereditary cancer	Hereditary cancer	N/A	N/A	ClinVar

Show/Hide Text Mining Associations (36)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenomatous Polyposis Coli	Associate	39519399
Alternating hemiplegia of childhood	Inhibit	31138797
Anemia Hemolytic	Associate	20160754, 22510687
Azoospermia	Associate	35172124
Azoospermia Nonobstructive	Associate	36017582
Bloom Syndrome	Associate	20064455, 22392978
Bone Marrow Failure Disorders	Associate	37450374
Breast Neoplasms	Associate	25288723, 26130695, 27542569, 28033443, 28591191, 28702895, 28837162, 29231814, 29351780, 33118316, 34282249, 35353237, 36315097, 36835452
Burkitt Lymphoma	Associate	30779244
Carcinoma Pancreatic Ductal	Associate	32113160
Carcinoma Renal Cell	Stimulate	34331411
Cardiac Output Low	Inhibit	36652992
Chordoma	Associate	37024492
Chromosome Aberrations	Associate	29231814
Chromosome Fragility	Associate	28837157, 28837162
Colorectal Neoplasms	Associate	33118316, 36356413
Drug Related Side Effects and Adverse Reactions	Associate	28837157, 28837162
Epileptic Syndromes	Associate	36835452
Fanconi Anemia	Associate	16116422, 19405097, 19423727, 20064455, 20347418, 20347429, 20670894, 22547783, 23698467, 23932590, 24003026, 24885126, 26825464, 27351285, 28837157, 35867033, 40447800 View all (2 more)
Friedreich Ataxia 1	Associate	20160754
Hereditary Breast and Ovarian Cancer Syndrome	Associate	30306255, 30927251, 31882575, 33099839
Hereditary pancreatitis	Associate	28687971
Inflammation	Associate	27351285
Intestinal Polyposis	Associate	36356413
Kidney Diseases	Associate	34067580
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	40344211
Leukemia Myeloid Acute	Associate	32868804
Medulloblastoma	Associate	28376765
Myelodysplastic Syndromes	Associate	36503307
Neoplasms	Associate	20160754, 26689913, 28687971, 28702895, 28837157, 28837162, 30942098, 34331411, 37024492, 40447800
Neoplastic Syndromes Hereditary	Associate	28050010
Ovarian Neoplasms	Associate	28033443, 28702895, 33036707, 36721777
Pancreatic Neoplasms	Associate	26483394, 32113160, 39256447
Primary Ovarian Insufficiency	Associate	29231814, 33036707, 36099812, 38521400
Sertoli Cell Only Syndrome	Associate	37296437
Triple Negative Breast Neoplasms	Associate	25288723, 28702895

FANCM (FA complementation group M)