Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
57693
Gene name Gene Name - the full gene name approved by the HGNC.
Zinc finger protein 317
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZNF317
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT030552 hsa-miR-24-3p qRT-PCR;Microarray 17686970
MIRT052222 hsa-let-7b-5p CLASH 23622248
MIRT041317 hsa-miR-193b-3p CLASH 23622248
MIRT295180 hsa-miR-519a-3p PAR-CLIP 20371350
MIRT295179 hsa-miR-519b-3p PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0005515 Function Protein binding IPI 21516116, 25416956, 31515488, 32296183
GO:0005634 Component Nucleus HDA 21630459
GO:0005634 Component Nucleus IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
613864 13507 ENSG00000130803
Protein
UniProt ID Q96PQ6
Protein name Zinc finger protein 317
Protein function May function as a transcription factor. May play an important role in erythroid maturation and lymphoid proliferation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 56 97 KRAB box Family
PF00096 zf-C2H2 222 244 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 250 272 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 278 300 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 306 328 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 334 356 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 390 412 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 418 440 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 446 468 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 502 524 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 530 552 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 558 580 Zinc finger, C2H2 type Domain
Tissue specificity TISSUE SPECIFICITY: Isoform 1 and isoform 2 are ubiquitously expressed. Isoform 3 and isoform 4 are expressed only in lymphocytes, spleen and lung. {ECO:0000269|PubMed:11688974}.
Sequence
MAALSPTFATSTQDSTCLQDSEFPVSSKDHSCPQNLDLFVCSGLEPHTPSVGSQESVTFQ
DVAVDFTEKEWPLLDSSQRKLYKDVMLENYSNLTSLG
YQVGKPSLISHLEQEEEPRTEER
GAHQGACADWETPSKTKWSLLMEDIFGKETPSGVTMERAGLGEKSTEYAHLFEVFGMDPH
LTQPMGRHAGKRPYHRRDYGVAFKGRPHLTQHMSMYDGRKMHECHQCQKAFTTSASLTRH
RRIH
TGEKPYECSDCGKAFNDPSALRSHARTHLKEKPFDCSQCGNAFRTLSALKIHMRVH
TGERPYKCDQCGKAYGRSCHLIAHKRTHTGERPYECHDCGKAFQHPSHLKEHVRNHTGEK
PYACTQCGKAFRWKSNFNLHKKNHMVEKTYECKECGKSFGDLVSRRKHMRIHIVKKPVEC
RQCGKTFRNQSILKTHMNSH
TGEKPYGCDLCGKAFSASSNLTAHRKIHTQERRYECAACG
KVFGDYLSRRRHMSVHLVKKRVECRQCGKAFRNQSTLKTHMRSHTGEKPYECDHCGKAFS
IGSNLNVHRRIH
TGEKPYECLVCGKAFSDHSSLRSHVKTHRGEKLFVSSVWKRLQ
Sequence length 595
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Hypercholesterolemia Hypercholesterolemia, Familial rs28942111, rs28942112, rs137852912, rs121908025, rs28942082, rs28942083, rs121908028, rs121908030, rs28942079, rs28942084, rs121908032, rs387906302, rs387906303, rs121908033, rs121908034
View all (1161 more)
22968135