FBRSL1 (fibrosin like 1)

Gene

• Entrez ID: 57666
• Gene name: Fibrosin like 1
• Gene symbol: FBRSL1
• Synonyms (NCBI Gene): -
• Chromosome: 12
• Chromosome location: 12q24.33

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT042565	hsa-miR-423-3p	CLASH	23622248
MIRT739638	hsa-miR-141	CLIP-seq
MIRT739639	hsa-miR-200a	CLIP-seq
MIRT739641	hsa-miR-3130-3p	CLIP-seq
MIRT990204	hsa-miR-3151	CLIP-seq
MIRT990205	hsa-miR-3613-3p	CLIP-seq
MIRT990206	hsa-miR-4447	CLIP-seq
MIRT990207	hsa-miR-4472	CLIP-seq
MIRT990208	hsa-miR-4505	CLIP-seq
MIRT990209	hsa-miR-4646-5p	CLIP-seq
MIRT990210	hsa-miR-4668-5p	CLIP-seq
MIRT990211	hsa-miR-491-5p	CLIP-seq
MIRT990212	hsa-miR-520d-5p	CLIP-seq
MIRT990213	hsa-miR-524-5p	CLIP-seq
MIRT990214	hsa-miR-544	CLIP-seq
MIRT990215	hsa-miR-548m	CLIP-seq
MIRT990216	hsa-miR-625	CLIP-seq
MIRT739640	hsa-miR-767-5p	CLIP-seq
MIRT990217	hsa-miR-885-5p	CLIP-seq
MIRT1548622	hsa-miR-1910	CLIP-seq
MIRT1548623	hsa-miR-3140-5p	CLIP-seq
MIRT1548624	hsa-miR-4786-3p	CLIP-seq
MIRT1993443	hsa-miR-1273e	CLIP-seq
MIRT1993444	hsa-miR-128	CLIP-seq
MIRT1993445	hsa-miR-1281	CLIP-seq
MIRT1993446	hsa-miR-1292	CLIP-seq
MIRT1993447	hsa-miR-139-5p	CLIP-seq
MIRT739638	hsa-miR-141	CLIP-seq
MIRT1993448	hsa-miR-142-5p	CLIP-seq
MIRT1993449	hsa-miR-147	CLIP-seq
MIRT1993450	hsa-miR-185	CLIP-seq
MIRT1548622	hsa-miR-1910	CLIP-seq
MIRT739639	hsa-miR-200a	CLIP-seq
MIRT1993451	hsa-miR-218	CLIP-seq
MIRT1993452	hsa-miR-2277-3p	CLIP-seq
MIRT1993453	hsa-miR-27a	CLIP-seq
MIRT1993454	hsa-miR-27b	CLIP-seq
MIRT739641	hsa-miR-3130-3p	CLIP-seq
MIRT1993455	hsa-miR-3134	CLIP-seq
MIRT1548623	hsa-miR-3140-5p	CLIP-seq
MIRT990204	hsa-miR-3151	CLIP-seq
MIRT1993456	hsa-miR-3168	CLIP-seq
MIRT1993457	hsa-miR-3176	CLIP-seq
MIRT1993458	hsa-miR-340	CLIP-seq
MIRT1993459	hsa-miR-3609	CLIP-seq
MIRT1993460	hsa-miR-3618	CLIP-seq
MIRT1993461	hsa-miR-3621	CLIP-seq
MIRT1993462	hsa-miR-3653	CLIP-seq
MIRT1993463	hsa-miR-3656	CLIP-seq
MIRT1993464	hsa-miR-3658	CLIP-seq
MIRT1993465	hsa-miR-3663-5p	CLIP-seq
MIRT1993466	hsa-miR-3691-3p	CLIP-seq
MIRT1993467	hsa-miR-3914	CLIP-seq
MIRT1993468	hsa-miR-3922-3p	CLIP-seq
MIRT1993469	hsa-miR-3922-5p	CLIP-seq
MIRT1993470	hsa-miR-4300	CLIP-seq
MIRT1993471	hsa-miR-4306	CLIP-seq
MIRT1993472	hsa-miR-4420	CLIP-seq
MIRT1993473	hsa-miR-4433	CLIP-seq
MIRT1993474	hsa-miR-4446-3p	CLIP-seq
MIRT990206	hsa-miR-4447	CLIP-seq
MIRT1993475	hsa-miR-4467	CLIP-seq
MIRT1993476	hsa-miR-4471	CLIP-seq
MIRT990207	hsa-miR-4472	CLIP-seq
MIRT1993477	hsa-miR-4481	CLIP-seq
MIRT1993478	hsa-miR-4488	CLIP-seq
MIRT1993479	hsa-miR-4492	CLIP-seq
MIRT1993480	hsa-miR-4498	CLIP-seq
MIRT1993481	hsa-miR-4530	CLIP-seq
MIRT1993482	hsa-miR-4534	CLIP-seq
MIRT1993483	hsa-miR-4632	CLIP-seq
MIRT1993484	hsa-miR-4638-3p	CLIP-seq
MIRT1993485	hsa-miR-4640-5p	CLIP-seq
MIRT1993486	hsa-miR-4644	CLIP-seq
MIRT990210	hsa-miR-4668-5p	CLIP-seq
MIRT1993487	hsa-miR-4685-5p	CLIP-seq
MIRT1993488	hsa-miR-4697-5p	CLIP-seq
MIRT1993489	hsa-miR-4726-5p	CLIP-seq
MIRT1993490	hsa-miR-4734	CLIP-seq
MIRT1993491	hsa-miR-4742-3p	CLIP-seq
MIRT1993492	hsa-miR-4745-5p	CLIP-seq
MIRT1993493	hsa-miR-4746-3p	CLIP-seq
MIRT1993494	hsa-miR-4758-5p	CLIP-seq
MIRT1993495	hsa-miR-4777-5p	CLIP-seq
MIRT1548624	hsa-miR-4786-3p	CLIP-seq
MIRT1993496	hsa-miR-489	CLIP-seq
MIRT990211	hsa-miR-491-5p	CLIP-seq
MIRT1993497	hsa-miR-503	CLIP-seq
MIRT1993498	hsa-miR-512-3p	CLIP-seq
MIRT990212	hsa-miR-520d-5p	CLIP-seq
MIRT1993499	hsa-miR-520g	CLIP-seq
MIRT1993500	hsa-miR-520h	CLIP-seq
MIRT990213	hsa-miR-524-5p	CLIP-seq
MIRT1993501	hsa-miR-548ah	CLIP-seq
MIRT990215	hsa-miR-548m	CLIP-seq
MIRT1993502	hsa-miR-572	CLIP-seq
MIRT1993503	hsa-miR-598	CLIP-seq
MIRT1993504	hsa-miR-599	CLIP-seq
MIRT1993505	hsa-miR-601	CLIP-seq
MIRT1993506	hsa-miR-604	CLIP-seq
MIRT990216	hsa-miR-625	CLIP-seq
MIRT1993507	hsa-miR-629	CLIP-seq
MIRT1993508	hsa-miR-636	CLIP-seq
MIRT1993509	hsa-miR-661	CLIP-seq
MIRT1993510	hsa-miR-665	CLIP-seq
MIRT1993511	hsa-miR-758	CLIP-seq
MIRT1993512	hsa-miR-762	CLIP-seq
MIRT739640	hsa-miR-767-5p	CLIP-seq
MIRT1993513	hsa-miR-802	CLIP-seq
MIRT990217	hsa-miR-885-5p	CLIP-seq
MIRT1993514	hsa-miR-920	CLIP-seq
MIRT2227326	hsa-miR-1249	CLIP-seq
MIRT1993444	hsa-miR-128	CLIP-seq
MIRT1993445	hsa-miR-1281	CLIP-seq
MIRT1993446	hsa-miR-1292	CLIP-seq
MIRT2227327	hsa-miR-1299	CLIP-seq
MIRT2227328	hsa-miR-153	CLIP-seq
MIRT1993450	hsa-miR-185	CLIP-seq
MIRT1548622	hsa-miR-1910	CLIP-seq
MIRT1993453	hsa-miR-27a	CLIP-seq
MIRT1993454	hsa-miR-27b	CLIP-seq
MIRT2227329	hsa-miR-3074-3p	CLIP-seq
MIRT2227330	hsa-miR-3135b	CLIP-seq
MIRT1548623	hsa-miR-3140-5p	CLIP-seq
MIRT990204	hsa-miR-3151	CLIP-seq
MIRT1993457	hsa-miR-3176	CLIP-seq
MIRT2227331	hsa-miR-3607-3p	CLIP-seq
MIRT2227332	hsa-miR-3620	CLIP-seq
MIRT1993461	hsa-miR-3621	CLIP-seq
MIRT2227333	hsa-miR-3652	CLIP-seq
MIRT1993462	hsa-miR-3653	CLIP-seq
MIRT1993463	hsa-miR-3656	CLIP-seq
MIRT1993464	hsa-miR-3658	CLIP-seq
MIRT2227334	hsa-miR-3686	CLIP-seq
MIRT1993466	hsa-miR-3691-3p	CLIP-seq
MIRT1993468	hsa-miR-3922-3p	CLIP-seq
MIRT1993469	hsa-miR-3922-5p	CLIP-seq
MIRT2227335	hsa-miR-421	CLIP-seq
MIRT2227336	hsa-miR-4261	CLIP-seq
MIRT1993471	hsa-miR-4306	CLIP-seq
MIRT1993472	hsa-miR-4420	CLIP-seq
MIRT2227337	hsa-miR-4430	CLIP-seq
MIRT1993474	hsa-miR-4446-3p	CLIP-seq
MIRT990206	hsa-miR-4447	CLIP-seq
MIRT1993475	hsa-miR-4467	CLIP-seq
MIRT1993476	hsa-miR-4471	CLIP-seq
MIRT990207	hsa-miR-4472	CLIP-seq
MIRT2227338	hsa-miR-448	CLIP-seq
MIRT1993477	hsa-miR-4481	CLIP-seq
MIRT1993478	hsa-miR-4488	CLIP-seq
MIRT1993479	hsa-miR-4492	CLIP-seq
MIRT1993480	hsa-miR-4498	CLIP-seq
MIRT1993481	hsa-miR-4530	CLIP-seq
MIRT1993483	hsa-miR-4632	CLIP-seq
MIRT1993485	hsa-miR-4640-5p	CLIP-seq
MIRT1993486	hsa-miR-4644	CLIP-seq
MIRT990210	hsa-miR-4668-5p	CLIP-seq
MIRT1993487	hsa-miR-4685-5p	CLIP-seq
MIRT1993488	hsa-miR-4697-5p	CLIP-seq
MIRT2227339	hsa-miR-4709-5p	CLIP-seq
MIRT1993489	hsa-miR-4726-5p	CLIP-seq
MIRT1993490	hsa-miR-4734	CLIP-seq
MIRT1993491	hsa-miR-4742-3p	CLIP-seq
MIRT1993492	hsa-miR-4745-5p	CLIP-seq
MIRT1993494	hsa-miR-4758-5p	CLIP-seq
MIRT2227340	hsa-miR-4782-5p	CLIP-seq
MIRT1993496	hsa-miR-489	CLIP-seq
MIRT990211	hsa-miR-491-5p	CLIP-seq
MIRT1993497	hsa-miR-503	CLIP-seq
MIRT2227341	hsa-miR-516b	CLIP-seq
MIRT990212	hsa-miR-520d-5p	CLIP-seq
MIRT990213	hsa-miR-524-5p	CLIP-seq
MIRT990215	hsa-miR-548m	CLIP-seq
MIRT2227342	hsa-miR-553	CLIP-seq
MIRT2227343	hsa-miR-570	CLIP-seq
MIRT1993506	hsa-miR-604	CLIP-seq
MIRT990216	hsa-miR-625	CLIP-seq
MIRT1993507	hsa-miR-629	CLIP-seq
MIRT1993509	hsa-miR-661	CLIP-seq
MIRT1993511	hsa-miR-758	CLIP-seq
MIRT1993512	hsa-miR-762	CLIP-seq
MIRT739640	hsa-miR-767-5p	CLIP-seq
MIRT2227344	hsa-miR-875-3p	CLIP-seq
MIRT990217	hsa-miR-885-5p	CLIP-seq
MIRT2227345	hsa-miR-889	CLIP-seq
MIRT1993444	hsa-miR-128	CLIP-seq
MIRT1993449	hsa-miR-147	CLIP-seq
MIRT1993453	hsa-miR-27a	CLIP-seq
MIRT1993454	hsa-miR-27b	CLIP-seq
MIRT1993457	hsa-miR-3176	CLIP-seq
MIRT2227332	hsa-miR-3620	CLIP-seq
MIRT1993466	hsa-miR-3691-3p	CLIP-seq
MIRT1993468	hsa-miR-3922-3p	CLIP-seq
MIRT1993474	hsa-miR-4446-3p	CLIP-seq
MIRT990206	hsa-miR-4447	CLIP-seq
MIRT990207	hsa-miR-4472	CLIP-seq
MIRT1993477	hsa-miR-4481	CLIP-seq
MIRT1993478	hsa-miR-4488	CLIP-seq
MIRT1993479	hsa-miR-4492	CLIP-seq
MIRT1993480	hsa-miR-4498	CLIP-seq
MIRT1993481	hsa-miR-4530	CLIP-seq
MIRT1993488	hsa-miR-4697-5p	CLIP-seq
MIRT1993492	hsa-miR-4745-5p	CLIP-seq
MIRT1993494	hsa-miR-4758-5p	CLIP-seq
MIRT1993504	hsa-miR-599	CLIP-seq
MIRT1993512	hsa-miR-762	CLIP-seq
MIRT1993473	hsa-miR-4433	CLIP-seq
MIRT1993483	hsa-miR-4632	CLIP-seq
MIRT1993498	hsa-miR-512-3p	CLIP-seq
MIRT1993510	hsa-miR-665	CLIP-seq
MIRT2531289	hsa-miR-1207-5p	CLIP-seq
MIRT2531290	hsa-miR-3622b-5p	CLIP-seq
MIRT2531291	hsa-miR-4253	CLIP-seq
MIRT2531292	hsa-miR-4761-3p	CLIP-seq
MIRT2531293	hsa-miR-4763-3p	CLIP-seq
MIRT2531294	hsa-miR-486-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889

Other IDs

• MIM: 620123
• HGNC: 29308
• e!Ensembl: ENSG00000112787

Protein

• UniProt ID: Q9HCM7
• Protein name: Fibrosin-1-like protein (AUTS2-like protein) (HBV X-transactivated gene 9 protein) (HBV XAg-transactivated protein 9)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15336	Auts2	587 → 791	Autism susceptibility gene 2 protein	Family

• Sequence:

  MEAKVRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPA
  PRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPR
  ESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDS
  VLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAK
  AGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQ
  PPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHL
  STSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQ
  SAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDK
  YAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVVKVS
  TCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIAW
  QIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPA
  SNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEG
  SSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLL
  EKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMP
  ARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRG
  LELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPAL
  DGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTT
  PLGGLGPGEARDYSPSRNPPEVEAR

• Sequence length: 1045

Pathways

KEGG:

Polycomb repressive complex

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Moyamoya angiopathy	Likely pathogenic	rs2040109939	RCV004704493

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
FBRSL1-associated neurodevelopmental syndrome	Uncertain significance	rs1299339182	RCV002227594
FBRSL1-related disorder	Uncertain significance; Benign; Likely benign	rs1274787495, rs1420336153, rs2541118501, rs538547455, rs180891480	RCV003414540 RCV003402122 RCV003397851 RCV003904782 RCV003943847
See cases	Likely benign	rs749751607, rs2541447147	RCV003151941 RCV003151942
Syndromic disease	Benign	rs538547455	RCV003994606

Associations from Text Mining
Disease Name	Relationship Type	References
Asthma	Associate	35597955
Melanoma	Associate	23659246