Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	57636
Gene name Gene Name - the full gene name approved by the HGNC.	Rho GTPase activating protein 23
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ARHGAP23
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q12
Summary Summary of gene provided in NCBI Entrez Gene.	The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactiv

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miRTarBase ID	miRNA	Experiments
MIRT794102	hsa-miR-101	CLIP-seq
MIRT794103	hsa-miR-1254	CLIP-seq
MIRT794104	hsa-miR-144	CLIP-seq
MIRT794105	hsa-miR-1587	CLIP-seq
MIRT794106	hsa-miR-3116	CLIP-seq
MIRT794107	hsa-miR-3182	CLIP-seq
MIRT794108	hsa-miR-378g	CLIP-seq
MIRT794109	hsa-miR-3944-5p	CLIP-seq
MIRT794110	hsa-miR-4299	CLIP-seq
MIRT794111	hsa-miR-4417	CLIP-seq
MIRT794112	hsa-miR-4492	CLIP-seq
MIRT794113	hsa-miR-4498	CLIP-seq
MIRT794114	hsa-miR-4656	CLIP-seq
MIRT794115	hsa-miR-4675	CLIP-seq
MIRT794116	hsa-miR-4691-3p	CLIP-seq
MIRT794117	hsa-miR-4699-3p	CLIP-seq
MIRT794118	hsa-miR-4741	CLIP-seq
MIRT794119	hsa-miR-509-3p	CLIP-seq
MIRT794120	hsa-miR-519a	CLIP-seq
MIRT794121	hsa-miR-519b-3p	CLIP-seq
MIRT794122	hsa-miR-519c-3p	CLIP-seq
MIRT794123	hsa-miR-541	CLIP-seq
MIRT794124	hsa-miR-550a	CLIP-seq
MIRT794125	hsa-miR-582-5p	CLIP-seq
MIRT794126	hsa-miR-654-5p	CLIP-seq
MIRT794127	hsa-miR-661	CLIP-seq
MIRT794128	hsa-miR-762	CLIP-seq
MIRT1545481	hsa-miR-491-5p	CLIP-seq
MIRT1555978	hsa-miR-3144-5p	CLIP-seq
MIRT1555979	hsa-miR-4716-3p	CLIP-seq
MIRT2174151	hsa-miR-153	CLIP-seq
MIRT794108	hsa-miR-378g	CLIP-seq
MIRT2174152	hsa-miR-3941	CLIP-seq
MIRT2174153	hsa-miR-448	CLIP-seq
MIRT794116	hsa-miR-4691-3p	CLIP-seq
MIRT2426393	hsa-miR-3151	CLIP-seq
MIRT2426394	hsa-miR-4447	CLIP-seq
MIRT2426395	hsa-miR-4472	CLIP-seq
MIRT794117	hsa-miR-4699-3p	CLIP-seq
MIRT1545481	hsa-miR-491-5p	CLIP-seq
MIRT2435471	hsa-miR-1909	CLIP-seq
MIRT2435472	hsa-miR-214	CLIP-seq
MIRT2435473	hsa-miR-3619-5p	CLIP-seq
MIRT2435474	hsa-miR-609	CLIP-seq
MIRT2435475	hsa-miR-761	CLIP-seq
MIRT2435471	hsa-miR-1909	CLIP-seq
MIRT2435472	hsa-miR-214	CLIP-seq
MIRT2435473	hsa-miR-3619-5p	CLIP-seq
MIRT2443907	hsa-miR-4765	CLIP-seq
MIRT2443908	hsa-miR-542-3p	CLIP-seq
MIRT2435474	hsa-miR-609	CLIP-seq
MIRT2435475	hsa-miR-761	CLIP-seq
MIRT2477831	hsa-miR-1	CLIP-seq
MIRT2477832	hsa-miR-1253	CLIP-seq
MIRT2477833	hsa-miR-1321	CLIP-seq
MIRT2477834	hsa-miR-147	CLIP-seq
MIRT2477835	hsa-miR-1470	CLIP-seq
MIRT2477836	hsa-miR-188-5p	CLIP-seq
MIRT2435471	hsa-miR-1909	CLIP-seq
MIRT2477837	hsa-miR-197	CLIP-seq
MIRT2477838	hsa-miR-206	CLIP-seq
MIRT2435472	hsa-miR-214	CLIP-seq
MIRT2477839	hsa-miR-298	CLIP-seq
MIRT2477840	hsa-miR-3126-5p	CLIP-seq
MIRT1555978	hsa-miR-3144-5p	CLIP-seq
MIRT2477841	hsa-miR-3148	CLIP-seq
MIRT2477842	hsa-miR-3150a-3p	CLIP-seq
MIRT2426393	hsa-miR-3151	CLIP-seq
MIRT2477843	hsa-miR-3175	CLIP-seq
MIRT2477844	hsa-miR-3176	CLIP-seq
MIRT794107	hsa-miR-3182	CLIP-seq
MIRT2477845	hsa-miR-3185	CLIP-seq
MIRT2477846	hsa-miR-329	CLIP-seq
MIRT2477847	hsa-miR-3616-3p	CLIP-seq
MIRT2435473	hsa-miR-3619-5p	CLIP-seq
MIRT2477848	hsa-miR-362-3p	CLIP-seq
MIRT2477849	hsa-miR-3650	CLIP-seq
MIRT2477850	hsa-miR-3673	CLIP-seq
MIRT2477851	hsa-miR-3688-3p	CLIP-seq
MIRT2477852	hsa-miR-3689a-3p	CLIP-seq
MIRT2477853	hsa-miR-3689c	CLIP-seq
MIRT794108	hsa-miR-378g	CLIP-seq
MIRT2477854	hsa-miR-3911	CLIP-seq
MIRT2477855	hsa-miR-3922-3p	CLIP-seq
MIRT2477856	hsa-miR-3936	CLIP-seq
MIRT2174152	hsa-miR-3941	CLIP-seq
MIRT2477857	hsa-miR-4271	CLIP-seq
MIRT2477858	hsa-miR-4292	CLIP-seq
MIRT794110	hsa-miR-4299	CLIP-seq
MIRT2477859	hsa-miR-4308	CLIP-seq
MIRT794111	hsa-miR-4417	CLIP-seq
MIRT2477860	hsa-miR-4419a	CLIP-seq
MIRT2477861	hsa-miR-4434	CLIP-seq
MIRT2477862	hsa-miR-4436b-3p	CLIP-seq
MIRT2426394	hsa-miR-4447	CLIP-seq
MIRT2477863	hsa-miR-4455	CLIP-seq
MIRT2426395	hsa-miR-4472	CLIP-seq
MIRT2477864	hsa-miR-4488	CLIP-seq
MIRT794112	hsa-miR-4492	CLIP-seq
MIRT794113	hsa-miR-4498	CLIP-seq
MIRT2477865	hsa-miR-4510	CLIP-seq
MIRT2477866	hsa-miR-4516	CLIP-seq
MIRT2477867	hsa-miR-4667-3p	CLIP-seq
MIRT2477868	hsa-miR-4697-5p	CLIP-seq
MIRT794117	hsa-miR-4699-3p	CLIP-seq
MIRT2477869	hsa-miR-4710	CLIP-seq
MIRT1555979	hsa-miR-4716-3p	CLIP-seq
MIRT2477870	hsa-miR-4725-3p	CLIP-seq
MIRT2477871	hsa-miR-4728-5p	CLIP-seq
MIRT2477872	hsa-miR-4739	CLIP-seq
MIRT2477873	hsa-miR-4756-5p	CLIP-seq
MIRT2443907	hsa-miR-4765	CLIP-seq
MIRT1545481	hsa-miR-491-5p	CLIP-seq
MIRT794119	hsa-miR-509-3p	CLIP-seq
MIRT794123	hsa-miR-541	CLIP-seq
MIRT2477874	hsa-miR-583	CLIP-seq
MIRT2477875	hsa-miR-603	CLIP-seq
MIRT2435474	hsa-miR-609	CLIP-seq
MIRT2477876	hsa-miR-613	CLIP-seq
MIRT2477877	hsa-miR-619	CLIP-seq
MIRT2477878	hsa-miR-634	CLIP-seq
MIRT2477879	hsa-miR-644	CLIP-seq
MIRT794126	hsa-miR-654-5p	CLIP-seq
MIRT2477880	hsa-miR-670	CLIP-seq
MIRT2435475	hsa-miR-761	CLIP-seq
MIRT794128	hsa-miR-762	CLIP-seq
MIRT2477881	hsa-miR-885-3p	CLIP-seq
MIRT2477882	hsa-miR-939	CLIP-seq
MIRT2477831	hsa-miR-1	CLIP-seq
MIRT2477833	hsa-miR-1321	CLIP-seq
MIRT2477834	hsa-miR-147	CLIP-seq
MIRT2477835	hsa-miR-1470	CLIP-seq
MIRT2477836	hsa-miR-188-5p	CLIP-seq
MIRT2435471	hsa-miR-1909	CLIP-seq
MIRT2477837	hsa-miR-197	CLIP-seq
MIRT2477838	hsa-miR-206	CLIP-seq
MIRT2435472	hsa-miR-214	CLIP-seq
MIRT2477840	hsa-miR-3126-5p	CLIP-seq
MIRT1555978	hsa-miR-3144-5p	CLIP-seq
MIRT2477841	hsa-miR-3148	CLIP-seq
MIRT2426393	hsa-miR-3151	CLIP-seq
MIRT2477844	hsa-miR-3176	CLIP-seq
MIRT2477845	hsa-miR-3185	CLIP-seq
MIRT2477846	hsa-miR-329	CLIP-seq
MIRT2477847	hsa-miR-3616-3p	CLIP-seq
MIRT2435473	hsa-miR-3619-5p	CLIP-seq
MIRT2477848	hsa-miR-362-3p	CLIP-seq
MIRT2477849	hsa-miR-3650	CLIP-seq
MIRT2477850	hsa-miR-3673	CLIP-seq
MIRT2477851	hsa-miR-3688-3p	CLIP-seq
MIRT2477852	hsa-miR-3689a-3p	CLIP-seq
MIRT2477853	hsa-miR-3689c	CLIP-seq
MIRT794108	hsa-miR-378g	CLIP-seq
MIRT2477854	hsa-miR-3911	CLIP-seq
MIRT2477855	hsa-miR-3922-3p	CLIP-seq
MIRT2477856	hsa-miR-3936	CLIP-seq
MIRT2174152	hsa-miR-3941	CLIP-seq
MIRT2477857	hsa-miR-4271	CLIP-seq
MIRT2477858	hsa-miR-4292	CLIP-seq
MIRT794110	hsa-miR-4299	CLIP-seq
MIRT2477859	hsa-miR-4308	CLIP-seq
MIRT2477860	hsa-miR-4419a	CLIP-seq
MIRT2426394	hsa-miR-4447	CLIP-seq
MIRT2477863	hsa-miR-4455	CLIP-seq
MIRT2426395	hsa-miR-4472	CLIP-seq
MIRT2477864	hsa-miR-4488	CLIP-seq
MIRT794112	hsa-miR-4492	CLIP-seq
MIRT794113	hsa-miR-4498	CLIP-seq
MIRT2477865	hsa-miR-4510	CLIP-seq
MIRT2477867	hsa-miR-4667-3p	CLIP-seq
MIRT2477868	hsa-miR-4697-5p	CLIP-seq
MIRT2477869	hsa-miR-4710	CLIP-seq
MIRT1555979	hsa-miR-4716-3p	CLIP-seq
MIRT2477870	hsa-miR-4725-3p	CLIP-seq
MIRT2675259	hsa-miR-4725-5p	CLIP-seq
MIRT2477871	hsa-miR-4728-5p	CLIP-seq
MIRT2477872	hsa-miR-4739	CLIP-seq
MIRT2477873	hsa-miR-4756-5p	CLIP-seq
MIRT2443907	hsa-miR-4765	CLIP-seq
MIRT1545481	hsa-miR-491-5p	CLIP-seq
MIRT2675260	hsa-miR-504	CLIP-seq
MIRT794123	hsa-miR-541	CLIP-seq
MIRT2477874	hsa-miR-583	CLIP-seq
MIRT2477875	hsa-miR-603	CLIP-seq
MIRT2435474	hsa-miR-609	CLIP-seq
MIRT2477876	hsa-miR-613	CLIP-seq
MIRT2477877	hsa-miR-619	CLIP-seq
MIRT2477878	hsa-miR-634	CLIP-seq
MIRT2477879	hsa-miR-644	CLIP-seq
MIRT794126	hsa-miR-654-5p	CLIP-seq
MIRT2477880	hsa-miR-670	CLIP-seq
MIRT2435475	hsa-miR-761	CLIP-seq
MIRT794128	hsa-miR-762	CLIP-seq
MIRT2477881	hsa-miR-885-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005096	Function	GTPase activator activity	IEA
GO:0005096	Function	GTPase activator activity	TAS
GO:0005829	Component	Cytosol	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS
GO:0070062	Component	Extracellular exosome	HDA	19199708

MIM	HGNC	e!Ensembl
610590	29293	ENSG00000275832

Protein

UniProt ID

Q9P227

Protein name

Rho GTPase-activating protein 23 (Rho-type GTPase-activating protein 23)

Protein function

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF17820	PDZ_6	99 → 152	PDZ domain	Domain
PF15410	PH_9	690 → 806	Pleckstrin homology domain	Domain
PF00620	RhoGAP	920 → 1074	RhoGAP domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in placenta, prostate, hippocampus and brain medulla. Also expressed in brain tumor, salivary gland tumor, head and neck tumor. {ECO:0000269|PubMed:15254754}.

Sequence

MNGVAFCLVGIPPRPEPRPPQLPLGPRDGCSPRRPFPWQGPRTLLLYKSPQDGFGFTLRH
FIVYPPESAVHCSLKEEENGGRGGGPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRL
VKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNEPYSGEAR
SIPEPPPICYPRKTYAPPARASTRATMVPEPTSALPSDPRSPAAWSDPGLRVPPAARAHL
DNSSLGMSQPRPSPGAFPHLSSEPRTPRAFPEPGSRVPPSRLECQQALSHWLSNQVPRRA
GERRCPAMAPRARSASQDRLEEVAAPRPWPCSTSQDALSQLGQEGWHRARSDDYLSRATR
SAEALGPGALVSPRFERCGWASQRSSARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYR
SYSPSFQRRTGLLHALSFRDSPFGGLPTFNLAQSPASFPPEASEPPRVVRPEPSTRALEP
PAEDRGDEVVLRQKPPTGRKVQLTPARQMNLGFGDESPEPEASGRGERLGRKVAPLATTE
DSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSSPTFTFTLGRHYSQD
CSSIKAGRRSSYLLAITTERSKSCDDGLNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSL
DSWGTSEDADAPSKRHSTSDLSDATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYA
ALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTT
ADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDPGCANQALISKKLNDYRKVSHSSGPKA
DSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP
RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRG
PGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKL
IRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMP
DRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVPNIEYLLPNIGRTVPPGDPGSDS
TTCSSAKSKGSWAPKKEPYAREMLAISFISAVNRKRKKRREARGLGSSTDDDSEQEAHKP
GAGATAPGTQERPQGPLPGAVAPEAPGRLSPPAAPEERPAADTRSIVSGYSTLSTMDRSV
CSGASGRRAGAGDEADDERSELSHVETDTEGAAGAGPGGRLTRRPSFSSHHLMPCDTLAR
RRLARGRPDGEGAGRGGPRAPEPPGSASSSSQESLRPPAAALASRPSRMEALRLRLRGTA
DDMLAVRLRRPLSPETRRRRSSWRRHTVVVQSPLTDLNFNEWKELGGGGPPEPAGARAHS
DNKDSGLSSLESTKARAPSSAASQPPAPGDTGSLQSQPPRRSAASRLHQCL

Sequence length

1491

Interactions

View interactions

	Reactome
			Rho GTPase cycle

ARHGAP23 (Rho GTPase activating protein 23)