LRRN1 (leucine rich repeat neuronal 1)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
57633
Gene name Gene Name - the full gene name approved by the HGNC.
Leucine rich repeat neuronal 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
LRRN1
Synonyms (NCBI Gene) Gene synonyms aliases
FIGLER3, NLRR-1, NLRR1
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p26.2
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(22)
miRTarBase ID miRNA Experiments Reference
MIRT019163 hsa-miR-335-5p Microarray 18185580
MIRT023145 hsa-miR-124-3p Microarray 18668037
MIRT049961 hsa-miR-30a-5p CLASH 23622248
MIRT1120939 hsa-miR-1246 CLIP-seq
MIRT1120940 hsa-miR-4703-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(5)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005615 Component Extracellular space IBA 21873635
GO:0016021 Component Integral component of membrane IEA
GO:0031012 Component Extracellular matrix IBA 21873635
GO:0051965 Process Positive regulation of synapse assembly IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
619623 20980 ENSG00000175928
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q6UXK5
Protein name Leucine-rich repeat neuronal protein 1 (Neuronal leucine-rich repeat protein 1) (NLRR-1)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13855 LRR_8 119 → 179 Leucine rich repeat Repeat
PF13855 LRR_8 167 → 224 Leucine rich repeat Repeat
PF13855 LRR_8 215 → 275 Leucine rich repeat Repeat
PF07679 I-set 426 → 516 Immunoglobulin I-set domain Domain
Sequence 
MARMSFVIAACQLVLGLLMTSLTESSIQNSECPQLCVCEIRPWFTPQSTYREATTVDCND
LRLTRIPSNLSSDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQ
LTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLK
VIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDS
LESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGEL
VSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESL
PNLREISIHSNPLRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYKGHQVKEVLIQDSSE
QCLPMISHDSFPNRLNVDIGTTVFLDCRAMAEPEPEIYWVTPIGNKITVETLSDKYKLSS
EGTLEISNIQIEDSGRYTCVAQNVQGADTRVATIKVNGTLLDGTQVLKIYVKQTESHSIL
VSWKVNSNVMTSNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSN
IHQQTQKSCVNVTTKNAAFAVDISDQETSTALAAVMGSMFAVISLASIAVYFAKRFKRKN
YHHSLKKYMQKTSSIPLNELYPPLINLWEGDSEKDKDGSADTKPTQVDTSRSYYMW
Sequence length 716
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Narcolepsy Narcolepsy rs104894574, rs387906655 19629137
Show/Hide Text Mining Associations (9)
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Associate 22491060, 23478628
Alzheimer Disease Associate 24731980
Carcinoma Non Small Cell Lung Associate 22491060
Carcinoma Renal Cell Associate 24977159
Carcinoma Squamous Cell Associate 22491060, 23478628
Intellectual Disability Associate 23040932
Neoplasm Metastasis Associate 22491060
Neoplasms Associate 22491060, 23478628, 24977159
Uterine Cervical Neoplasms Associate 23478628