LRRN1 (leucine rich repeat neuronal 1)

Gene

• Entrez ID: 57633
• Gene name: Leucine rich repeat neuronal 1
• Gene symbol: LRRN1
• Synonyms (NCBI Gene): FIGLER3, NLRR-1, NLRR1
• Chromosome: 3
• Chromosome location: 3p26.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019163	hsa-miR-335-5p	Microarray	18185580
MIRT023145	hsa-miR-124-3p	Microarray	18668037
MIRT049961	hsa-miR-30a-5p	CLASH	23622248
MIRT1120939	hsa-miR-1246	CLIP-seq
MIRT1120940	hsa-miR-4703-3p	CLIP-seq
MIRT1120941	hsa-miR-4764-5p	CLIP-seq
MIRT2034240	hsa-miR-3646	CLIP-seq
MIRT2264690	hsa-miR-1183	CLIP-seq
MIRT2264691	hsa-miR-323-3p	CLIP-seq
MIRT2264692	hsa-miR-4461	CLIP-seq
MIRT2264693	hsa-miR-548c-3p	CLIP-seq
MIRT2264694	hsa-miR-885-3p	CLIP-seq
MIRT2563589	hsa-miR-1323	CLIP-seq
MIRT2563590	hsa-miR-3129-3p	CLIP-seq
MIRT2563591	hsa-miR-4735-5p	CLIP-seq
MIRT2264693	hsa-miR-548c-3p	CLIP-seq
MIRT2563592	hsa-miR-548o	CLIP-seq
MIRT2563589	hsa-miR-1323	CLIP-seq
MIRT2563590	hsa-miR-3129-3p	CLIP-seq
MIRT2563591	hsa-miR-4735-5p	CLIP-seq
MIRT2264693	hsa-miR-548c-3p	CLIP-seq
MIRT2563592	hsa-miR-548o	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0038023	Function	Signaling receptor activity	IBA
GO:0051965	Process	Positive regulation of synapse assembly	IEA

Other IDs

• MIM: 619623
• HGNC: 20980
• e!Ensembl: ENSG00000175928

Protein

• UniProt ID: Q6UXK5
• Protein name: Leucine-rich repeat neuronal protein 1 (Neuronal leucine-rich repeat protein 1) (NLRR-1)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13855	LRR_8	119 → 179	Leucine rich repeat	Repeat
  PF13855	LRR_8	167 → 224	Leucine rich repeat	Repeat
  PF13855	LRR_8	215 → 275	Leucine rich repeat	Repeat
  PF07679	I-set	426 → 516	Immunoglobulin I-set domain	Domain

• Sequence:

  MARMSFVIAACQLVLGLLMTSLTESSIQNSECPQLCVCEIRPWFTPQSTYREATTVDCND
  LRLTRIPSNLSSDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQ
  LTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLK
  VIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDS
  LESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGEL
  VSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESL
  PNLREISIHSNPLRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYKGHQVKEVLIQDSSE
  QCLPMISHDSFPNRLNVDIGTTVFLDCRAMAEPEPEIYWVTPIGNKITVETLSDKYKLSS
  EGTLEISNIQIEDSGRYTCVAQNVQGADTRVATIKVNGTLLDGTQVLKIYVKQTESHSIL
  VSWKVNSNVMTSNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSN
  IHQQTQKSCVNVTTKNAAFAVDISDQETSTALAAVMGSMFAVISLASIAVYFAKRFKRKN
  YHHSLKKYMQKTSSIPLNELYPPLINLWEGDSEKDKDGSADTKPTQVDTSRSYYMW

• Sequence length: 716