NYAP2 (neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 57624
Gene name Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
Gene symbol NYAP2
Synonyms (NCBI Gene)
KIAA1486
Chromosome 2
Chromosome location 2q36.3
miRNA miRNA information provided by mirtarbase database.
42
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (42)
miRTarBase ID miRNA Experiments Reference
MIRT634509 hsa-miR-1306-5p HITS-CLIP 23824327
MIRT634508 hsa-miR-6890-3p HITS-CLIP 23824327
MIRT634507 hsa-miR-6736-3p HITS-CLIP 23824327
MIRT634506 hsa-miR-6840-3p HITS-CLIP 23824327
MIRT634505 hsa-miR-1915-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (7)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 33961781
GO:0043491 Process Phosphatidylinositol 3-kinase/protein kinase B signal transduction IBA
GO:0043491 Process Phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
GO:0043491 Process Phosphatidylinositol 3-kinase/protein kinase B signal transduction ISS
GO:0048812 Process Neuron projection morphogenesis IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
615478 29291 ENSG00000144460
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9P242
Protein name Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2
Protein function Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15439 NYAP_N 56 → 431 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Family
PF15452 NYAP_C 467 → 653 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Family
Sequence
Sequence length 653
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
55
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (55)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
AORTIC ATHEROSCLEROSIS — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BREAST CANCER — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (1)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Autism Spectrum Disorder Associate 28281572
★★★★★
★☆☆☆☆
Found in Text Mining only