Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
57606
Gene name Gene Name - the full gene name approved by the HGNC.
SLAIN motif family member 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLAIN2
Synonyms (NCBI Gene) Gene synonyms aliases
KIAA1458
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4p11
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT030692 hsa-miR-21-5p Microarray 18591254
MIRT093988 hsa-miR-409-3p PAR-CLIP 21572407
MIRT093983 hsa-miR-103a-3p PAR-CLIP 21572407
MIRT093984 hsa-miR-107 PAR-CLIP 21572407
MIRT093990 hsa-miR-944 PAR-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21646404, 26496610, 33961781
GO:0005737 Component Cytoplasm IEA
GO:0005813 Component Centrosome IDA 21399614
GO:0005829 Component Cytosol IDA
GO:0005856 Component Cytoskeleton IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610492 29282 ENSG00000109171
Protein
UniProt ID Q9P270
Protein name SLAIN motif-containing protein 2
Protein function Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase. {
PDB 3RDV
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15301 SLAIN 130 581 SLAIN motif-containing family Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed with highest levels in adult liver, testis and ovary, and lowest levels in adult pancreas and spleen and in fetal brain. {ECO:0000269|PubMed:10819331}.
Sequence
Sequence length 581
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Bipolar Disorder Bipolar disorder N/A N/A GWAS
Crohn Disease Crohn's disease N/A N/A GWAS
Inflammatory Bowel Disease Inflammatory bowel disease N/A N/A GWAS
Schizophrenia Schizophrenia N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Colorectal Neoplasms Associate 30797712
Dementia Associate 28600779
Intellectual Disability Associate 28600779
Neoplasm Metastasis Associate 30797712