Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	57580
Gene name Gene Name - the full gene name approved by the HGNC.	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PREX1
Synonyms (NCBI Gene) Gene synonyms aliases	P-REX1
Chromosome Chromosome number	20
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	20q13.13
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is foun

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miRTarBase ID	miRNA	Experiments	Reference
MIRT002783	hsa-miR-1-3p	Microarray	15685193
MIRT002783	hsa-miR-1-3p	Microarray;Other	15685193
MIRT726858	hsa-miR-27a-3p	HITS-CLIP	22473208
MIRT726856	hsa-miR-27b-3p	HITS-CLIP	22473208
MIRT1261056	hsa-miR-1	CLIP-seq
MIRT1261057	hsa-miR-106a	CLIP-seq
MIRT1261058	hsa-miR-106b	CLIP-seq
MIRT1261059	hsa-miR-1207-5p	CLIP-seq
MIRT1261060	hsa-miR-1226	CLIP-seq
MIRT1261061	hsa-miR-1237	CLIP-seq
MIRT1261062	hsa-miR-1252	CLIP-seq
MIRT1261063	hsa-miR-1253	CLIP-seq
MIRT1261064	hsa-miR-1264	CLIP-seq
MIRT1261065	hsa-miR-1266	CLIP-seq
MIRT1261066	hsa-miR-1267	CLIP-seq
MIRT1261067	hsa-miR-133a	CLIP-seq
MIRT1261068	hsa-miR-133b	CLIP-seq
MIRT1261069	hsa-miR-138	CLIP-seq
MIRT1261070	hsa-miR-142-5p	CLIP-seq
MIRT1261071	hsa-miR-147	CLIP-seq
MIRT1261072	hsa-miR-1470	CLIP-seq
MIRT1261073	hsa-miR-148a	CLIP-seq
MIRT1261074	hsa-miR-148b	CLIP-seq
MIRT1261075	hsa-miR-149	CLIP-seq
MIRT1261076	hsa-miR-152	CLIP-seq
MIRT1261077	hsa-miR-17	CLIP-seq
MIRT1261078	hsa-miR-1825	CLIP-seq
MIRT1261079	hsa-miR-1827	CLIP-seq
MIRT1261080	hsa-miR-1914	CLIP-seq
MIRT1261081	hsa-miR-1915	CLIP-seq
MIRT1261082	hsa-miR-194	CLIP-seq
MIRT1261083	hsa-miR-1972	CLIP-seq
MIRT1261084	hsa-miR-198	CLIP-seq
MIRT1261085	hsa-miR-203	CLIP-seq
MIRT1261086	hsa-miR-204	CLIP-seq
MIRT1261087	hsa-miR-206	CLIP-seq
MIRT1261088	hsa-miR-20a	CLIP-seq
MIRT1261089	hsa-miR-20b	CLIP-seq
MIRT1261090	hsa-miR-211	CLIP-seq
MIRT1261091	hsa-miR-214	CLIP-seq
MIRT1261092	hsa-miR-2355-5p	CLIP-seq
MIRT1261093	hsa-miR-2964a-5p	CLIP-seq
MIRT1261094	hsa-miR-3064-5p	CLIP-seq
MIRT1261095	hsa-miR-3134	CLIP-seq
MIRT1261096	hsa-miR-3138	CLIP-seq
MIRT1261097	hsa-miR-3150b-3p	CLIP-seq
MIRT1261098	hsa-miR-3157-5p	CLIP-seq
MIRT1261099	hsa-miR-3173-3p	CLIP-seq
MIRT1261100	hsa-miR-3180	CLIP-seq
MIRT1261101	hsa-miR-3180-3p	CLIP-seq
MIRT1261102	hsa-miR-3182	CLIP-seq
MIRT1261103	hsa-miR-3185	CLIP-seq
MIRT1261104	hsa-miR-3189-3p	CLIP-seq
MIRT1261105	hsa-miR-3189-5p	CLIP-seq
MIRT1261106	hsa-miR-3194-3p	CLIP-seq
MIRT1261107	hsa-miR-3196	CLIP-seq
MIRT1261108	hsa-miR-320e	CLIP-seq
MIRT1261109	hsa-miR-331-3p	CLIP-seq
MIRT1261110	hsa-miR-34b	CLIP-seq
MIRT1261111	hsa-miR-3611	CLIP-seq
MIRT1261112	hsa-miR-3612	CLIP-seq
MIRT1261113	hsa-miR-3615	CLIP-seq
MIRT1261114	hsa-miR-3619-5p	CLIP-seq
MIRT1261115	hsa-miR-3622a-3p	CLIP-seq
MIRT1261116	hsa-miR-3622b-3p	CLIP-seq
MIRT1261117	hsa-miR-3650	CLIP-seq
MIRT1261118	hsa-miR-3652	CLIP-seq
MIRT1261119	hsa-miR-3662	CLIP-seq
MIRT1261120	hsa-miR-3664-3p	CLIP-seq
MIRT1261121	hsa-miR-3671	CLIP-seq
MIRT1261122	hsa-miR-3673	CLIP-seq
MIRT1261123	hsa-miR-3691-3p	CLIP-seq
MIRT1261124	hsa-miR-377	CLIP-seq
MIRT1261125	hsa-miR-3910	CLIP-seq
MIRT1261126	hsa-miR-3911	CLIP-seq
MIRT1261127	hsa-miR-3918	CLIP-seq
MIRT1261128	hsa-miR-3937	CLIP-seq
MIRT1261129	hsa-miR-3940-5p	CLIP-seq
MIRT1261130	hsa-miR-410	CLIP-seq
MIRT1261131	hsa-miR-4267	CLIP-seq
MIRT1261132	hsa-miR-4269	CLIP-seq
MIRT1261133	hsa-miR-4281	CLIP-seq
MIRT1261134	hsa-miR-4299	CLIP-seq
MIRT1261135	hsa-miR-4419a	CLIP-seq
MIRT1261136	hsa-miR-4426	CLIP-seq
MIRT1261137	hsa-miR-4430	CLIP-seq
MIRT1261138	hsa-miR-4446-3p	CLIP-seq
MIRT1261139	hsa-miR-4449	CLIP-seq
MIRT1261140	hsa-miR-4456	CLIP-seq
MIRT1261141	hsa-miR-4474-3p	CLIP-seq
MIRT1261142	hsa-miR-4480	CLIP-seq
MIRT1261143	hsa-miR-4487	CLIP-seq
MIRT1261144	hsa-miR-4490	CLIP-seq
MIRT1261145	hsa-miR-4491	CLIP-seq
MIRT1261146	hsa-miR-4492	CLIP-seq
MIRT1261147	hsa-miR-4493	CLIP-seq
MIRT1261148	hsa-miR-4495	CLIP-seq
MIRT1261149	hsa-miR-4496	CLIP-seq
MIRT1261150	hsa-miR-4498	CLIP-seq
MIRT1261151	hsa-miR-4505	CLIP-seq
MIRT1261152	hsa-miR-4507	CLIP-seq
MIRT1261153	hsa-miR-4510	CLIP-seq
MIRT1261154	hsa-miR-4514	CLIP-seq
MIRT1261155	hsa-miR-4518	CLIP-seq
MIRT1261156	hsa-miR-4530	CLIP-seq
MIRT1261157	hsa-miR-4533	CLIP-seq
MIRT1261158	hsa-miR-4534	CLIP-seq
MIRT1261159	hsa-miR-4645-5p	CLIP-seq
MIRT1261160	hsa-miR-4646-3p	CLIP-seq
MIRT1261161	hsa-miR-4647	CLIP-seq
MIRT1261162	hsa-miR-4650-5p	CLIP-seq
MIRT1261163	hsa-miR-4652-3p	CLIP-seq
MIRT1261164	hsa-miR-4655-5p	CLIP-seq
MIRT1261165	hsa-miR-4657	CLIP-seq
MIRT1261166	hsa-miR-4662b	CLIP-seq
MIRT1261167	hsa-miR-4667-3p	CLIP-seq
MIRT1261168	hsa-miR-4673	CLIP-seq
MIRT1261169	hsa-miR-4685-5p	CLIP-seq
MIRT1261170	hsa-miR-4689	CLIP-seq
MIRT1261171	hsa-miR-4690-5p	CLIP-seq
MIRT1261172	hsa-miR-4691-3p	CLIP-seq
MIRT1261173	hsa-miR-4692	CLIP-seq
MIRT1261174	hsa-miR-4695-5p	CLIP-seq
MIRT1261175	hsa-miR-4701-5p	CLIP-seq
MIRT1261176	hsa-miR-4713-3p	CLIP-seq
MIRT1261177	hsa-miR-4724-3p	CLIP-seq
MIRT1261178	hsa-miR-4731-5p	CLIP-seq
MIRT1261179	hsa-miR-4740-3p	CLIP-seq
MIRT1261180	hsa-miR-4753-5p	CLIP-seq
MIRT1261181	hsa-miR-4755-3p	CLIP-seq
MIRT1261182	hsa-miR-4755-5p	CLIP-seq
MIRT1261183	hsa-miR-4757-3p	CLIP-seq
MIRT1261184	hsa-miR-4757-5p	CLIP-seq
MIRT1261185	hsa-miR-4762-5p	CLIP-seq
MIRT1261186	hsa-miR-4763-3p	CLIP-seq
MIRT1261187	hsa-miR-4774-5p	CLIP-seq
MIRT1261188	hsa-miR-4780	CLIP-seq
MIRT1261189	hsa-miR-4784	CLIP-seq
MIRT1261190	hsa-miR-4794	CLIP-seq
MIRT1261191	hsa-miR-4800-5p	CLIP-seq
MIRT1261192	hsa-miR-4802-5p	CLIP-seq
MIRT1261193	hsa-miR-490-3p	CLIP-seq
MIRT1261194	hsa-miR-516a-3p	CLIP-seq
MIRT1261195	hsa-miR-519a	CLIP-seq
MIRT1261196	hsa-miR-519b-3p	CLIP-seq
MIRT1261197	hsa-miR-519c-3p	CLIP-seq
MIRT1261198	hsa-miR-519d	CLIP-seq
MIRT1261199	hsa-miR-520a-5p	CLIP-seq
MIRT1261200	hsa-miR-525-5p	CLIP-seq
MIRT1261201	hsa-miR-542-5p	CLIP-seq
MIRT1261202	hsa-miR-548a-5p	CLIP-seq
MIRT1261203	hsa-miR-548ab	CLIP-seq
MIRT1261204	hsa-miR-548ak	CLIP-seq
MIRT1261205	hsa-miR-548b-5p	CLIP-seq
MIRT1261206	hsa-miR-548c-3p	CLIP-seq
MIRT1261207	hsa-miR-548c-5p	CLIP-seq
MIRT1261208	hsa-miR-548d-5p	CLIP-seq
MIRT1261209	hsa-miR-548g	CLIP-seq
MIRT1261210	hsa-miR-548h	CLIP-seq
MIRT1261211	hsa-miR-548i	CLIP-seq
MIRT1261212	hsa-miR-548j	CLIP-seq
MIRT1261213	hsa-miR-548k	CLIP-seq
MIRT1261214	hsa-miR-548l	CLIP-seq
MIRT1261215	hsa-miR-548t	CLIP-seq
MIRT1261216	hsa-miR-548w	CLIP-seq
MIRT1261217	hsa-miR-548y	CLIP-seq
MIRT1261218	hsa-miR-559	CLIP-seq
MIRT1261219	hsa-miR-581	CLIP-seq
MIRT1261220	hsa-miR-588	CLIP-seq
MIRT1261221	hsa-miR-607	CLIP-seq
MIRT1261222	hsa-miR-613	CLIP-seq
MIRT1261223	hsa-miR-619	CLIP-seq
MIRT1261224	hsa-miR-623	CLIP-seq
MIRT1261225	hsa-miR-637	CLIP-seq
MIRT1261226	hsa-miR-644	CLIP-seq
MIRT1261227	hsa-miR-650	CLIP-seq
MIRT1261228	hsa-miR-657	CLIP-seq
MIRT1261229	hsa-miR-663b	CLIP-seq
MIRT1261230	hsa-miR-671-5p	CLIP-seq
MIRT1261231	hsa-miR-760	CLIP-seq
MIRT1261232	hsa-miR-761	CLIP-seq
MIRT1261233	hsa-miR-762	CLIP-seq
MIRT1261234	hsa-miR-765	CLIP-seq
MIRT1261235	hsa-miR-93	CLIP-seq
MIRT1261236	hsa-miR-940	CLIP-seq
MIRT1261225	hsa-miR-637	CLIP-seq
MIRT1261056	hsa-miR-1	CLIP-seq
MIRT1261057	hsa-miR-106a	CLIP-seq
MIRT1261058	hsa-miR-106b	CLIP-seq
MIRT1261059	hsa-miR-1207-5p	CLIP-seq
MIRT2076780	hsa-miR-1225-3p	CLIP-seq
MIRT1261060	hsa-miR-1226	CLIP-seq
MIRT1261061	hsa-miR-1237	CLIP-seq
MIRT1261062	hsa-miR-1252	CLIP-seq
MIRT1261063	hsa-miR-1253	CLIP-seq
MIRT2076781	hsa-miR-125a-3p	CLIP-seq
MIRT1261064	hsa-miR-1264	CLIP-seq
MIRT1261066	hsa-miR-1267	CLIP-seq
MIRT2076782	hsa-miR-1291	CLIP-seq
MIRT2076783	hsa-miR-1305	CLIP-seq
MIRT1261067	hsa-miR-133a	CLIP-seq
MIRT1261068	hsa-miR-133b	CLIP-seq
MIRT1261069	hsa-miR-138	CLIP-seq
MIRT1261070	hsa-miR-142-5p	CLIP-seq
MIRT1261073	hsa-miR-148a	CLIP-seq
MIRT1261074	hsa-miR-148b	CLIP-seq
MIRT1261076	hsa-miR-152	CLIP-seq
MIRT1261077	hsa-miR-17	CLIP-seq
MIRT1261078	hsa-miR-1825	CLIP-seq
MIRT1261081	hsa-miR-1915	CLIP-seq
MIRT1261082	hsa-miR-194	CLIP-seq
MIRT1261084	hsa-miR-198	CLIP-seq
MIRT1261086	hsa-miR-204	CLIP-seq
MIRT1261087	hsa-miR-206	CLIP-seq
MIRT1261088	hsa-miR-20a	CLIP-seq
MIRT1261089	hsa-miR-20b	CLIP-seq
MIRT1261090	hsa-miR-211	CLIP-seq
MIRT1261091	hsa-miR-214	CLIP-seq
MIRT1261093	hsa-miR-2964a-5p	CLIP-seq
MIRT2076784	hsa-miR-296-5p	CLIP-seq
MIRT2076785	hsa-miR-3065-3p	CLIP-seq
MIRT2076786	hsa-miR-3065-5p	CLIP-seq
MIRT2076787	hsa-miR-3128	CLIP-seq
MIRT1261095	hsa-miR-3134	CLIP-seq
MIRT1261096	hsa-miR-3138	CLIP-seq
MIRT2076788	hsa-miR-3141	CLIP-seq
MIRT2076789	hsa-miR-3144-5p	CLIP-seq
MIRT1261097	hsa-miR-3150b-3p	CLIP-seq
MIRT2076790	hsa-miR-3151	CLIP-seq
MIRT2076791	hsa-miR-3158-3p	CLIP-seq
MIRT1261100	hsa-miR-3180	CLIP-seq
MIRT1261101	hsa-miR-3180-3p	CLIP-seq
MIRT1261102	hsa-miR-3182	CLIP-seq
MIRT1261103	hsa-miR-3185	CLIP-seq
MIRT1261104	hsa-miR-3189-3p	CLIP-seq
MIRT1261105	hsa-miR-3189-5p	CLIP-seq
MIRT2076792	hsa-miR-3191	CLIP-seq
MIRT1261107	hsa-miR-3196	CLIP-seq
MIRT2076793	hsa-miR-328	CLIP-seq
MIRT1261109	hsa-miR-331-3p	CLIP-seq
MIRT1261110	hsa-miR-34b	CLIP-seq
MIRT2076794	hsa-miR-3591-3p	CLIP-seq
MIRT1261111	hsa-miR-3611	CLIP-seq
MIRT1261112	hsa-miR-3612	CLIP-seq
MIRT2076795	hsa-miR-3613-3p	CLIP-seq
MIRT2076796	hsa-miR-361-3p	CLIP-seq
MIRT1261113	hsa-miR-3615	CLIP-seq
MIRT1261114	hsa-miR-3619-5p	CLIP-seq
MIRT1261115	hsa-miR-3622a-3p	CLIP-seq
MIRT1261116	hsa-miR-3622b-3p	CLIP-seq
MIRT1261117	hsa-miR-3650	CLIP-seq
MIRT1261121	hsa-miR-3671	CLIP-seq
MIRT1261122	hsa-miR-3673	CLIP-seq
MIRT1261123	hsa-miR-3691-3p	CLIP-seq
MIRT1261124	hsa-miR-377	CLIP-seq
MIRT1261127	hsa-miR-3918	CLIP-seq
MIRT2076797	hsa-miR-3934	CLIP-seq
MIRT1261128	hsa-miR-3937	CLIP-seq
MIRT1261129	hsa-miR-3940-5p	CLIP-seq
MIRT2076798	hsa-miR-3943	CLIP-seq
MIRT1261130	hsa-miR-410	CLIP-seq
MIRT2076799	hsa-miR-4261	CLIP-seq
MIRT1261131	hsa-miR-4267	CLIP-seq
MIRT1261132	hsa-miR-4269	CLIP-seq
MIRT2076800	hsa-miR-4270	CLIP-seq
MIRT1261133	hsa-miR-4281	CLIP-seq
MIRT2076801	hsa-miR-4283	CLIP-seq
MIRT2076802	hsa-miR-4290	CLIP-seq
MIRT2076803	hsa-miR-4292	CLIP-seq
MIRT2076804	hsa-miR-4314	CLIP-seq
MIRT1261135	hsa-miR-4419a	CLIP-seq
MIRT1261136	hsa-miR-4426	CLIP-seq
MIRT2076805	hsa-miR-4441	CLIP-seq
MIRT2076806	hsa-miR-4443	CLIP-seq
MIRT1261142	hsa-miR-4480	CLIP-seq
MIRT1261143	hsa-miR-4487	CLIP-seq
MIRT2076807	hsa-miR-4488	CLIP-seq
MIRT2076808	hsa-miR-4489	CLIP-seq
MIRT1261144	hsa-miR-4490	CLIP-seq
MIRT1261145	hsa-miR-4491	CLIP-seq
MIRT1261147	hsa-miR-4493	CLIP-seq
MIRT1261149	hsa-miR-4496	CLIP-seq
MIRT1261152	hsa-miR-4507	CLIP-seq
MIRT1261153	hsa-miR-4510	CLIP-seq
MIRT1261158	hsa-miR-4534	CLIP-seq
MIRT2076809	hsa-miR-4537	CLIP-seq
MIRT1261159	hsa-miR-4645-5p	CLIP-seq
MIRT1261161	hsa-miR-4647	CLIP-seq
MIRT1261162	hsa-miR-4650-5p	CLIP-seq
MIRT1261163	hsa-miR-4652-3p	CLIP-seq
MIRT2076810	hsa-miR-4652-5p	CLIP-seq
MIRT1261164	hsa-miR-4655-5p	CLIP-seq
MIRT1261165	hsa-miR-4657	CLIP-seq
MIRT1261166	hsa-miR-4662b	CLIP-seq
MIRT2076811	hsa-miR-4667-5p	CLIP-seq
MIRT2076812	hsa-miR-4668-3p	CLIP-seq
MIRT1261168	hsa-miR-4673	CLIP-seq
MIRT1261169	hsa-miR-4685-5p	CLIP-seq
MIRT1261170	hsa-miR-4689	CLIP-seq
MIRT2076813	hsa-miR-4697-5p	CLIP-seq
MIRT2076814	hsa-miR-4700-5p	CLIP-seq
MIRT1261176	hsa-miR-4713-3p	CLIP-seq
MIRT2076815	hsa-miR-4720-5p	CLIP-seq
MIRT2076816	hsa-miR-4721	CLIP-seq
MIRT2076817	hsa-miR-4722-5p	CLIP-seq
MIRT1261177	hsa-miR-4724-3p	CLIP-seq
MIRT2076818	hsa-miR-4726-3p	CLIP-seq
MIRT2076819	hsa-miR-4728-5p	CLIP-seq
MIRT2076820	hsa-miR-4733-5p	CLIP-seq
MIRT2076821	hsa-miR-4736	CLIP-seq
MIRT1261179	hsa-miR-4740-3p	CLIP-seq
MIRT1261180	hsa-miR-4753-5p	CLIP-seq
MIRT1261181	hsa-miR-4755-3p	CLIP-seq
MIRT1261182	hsa-miR-4755-5p	CLIP-seq
MIRT2076822	hsa-miR-4756-3p	CLIP-seq
MIRT1261183	hsa-miR-4757-3p	CLIP-seq
MIRT1261184	hsa-miR-4757-5p	CLIP-seq
MIRT1261185	hsa-miR-4762-5p	CLIP-seq
MIRT1261186	hsa-miR-4763-3p	CLIP-seq
MIRT1261187	hsa-miR-4774-5p	CLIP-seq
MIRT2076823	hsa-miR-4775	CLIP-seq
MIRT1261188	hsa-miR-4780	CLIP-seq
MIRT1261189	hsa-miR-4784	CLIP-seq
MIRT2076824	hsa-miR-4799-3p	CLIP-seq
MIRT1261191	hsa-miR-4800-5p	CLIP-seq
MIRT1261192	hsa-miR-4802-5p	CLIP-seq
MIRT2076825	hsa-miR-486-3p	CLIP-seq
MIRT1261193	hsa-miR-490-3p	CLIP-seq
MIRT2076826	hsa-miR-495	CLIP-seq
MIRT2076827	hsa-miR-498	CLIP-seq
MIRT2076828	hsa-miR-518a-3p	CLIP-seq
MIRT2076829	hsa-miR-518b	CLIP-seq
MIRT2076830	hsa-miR-518c	CLIP-seq
MIRT2076831	hsa-miR-518d-3p	CLIP-seq
MIRT2076832	hsa-miR-518f	CLIP-seq
MIRT1261195	hsa-miR-519a	CLIP-seq
MIRT1261196	hsa-miR-519b-3p	CLIP-seq
MIRT1261197	hsa-miR-519c-3p	CLIP-seq
MIRT1261198	hsa-miR-519d	CLIP-seq
MIRT1261199	hsa-miR-520a-5p	CLIP-seq
MIRT1261200	hsa-miR-525-5p	CLIP-seq
MIRT1261201	hsa-miR-542-5p	CLIP-seq
MIRT1261206	hsa-miR-548c-3p	CLIP-seq
MIRT1261215	hsa-miR-548t	CLIP-seq
MIRT2076833	hsa-miR-590-3p	CLIP-seq
MIRT2076834	hsa-miR-605	CLIP-seq
MIRT1261221	hsa-miR-607	CLIP-seq
MIRT1261222	hsa-miR-613	CLIP-seq
MIRT1261223	hsa-miR-619	CLIP-seq
MIRT1261224	hsa-miR-623	CLIP-seq
MIRT1261225	hsa-miR-637	CLIP-seq
MIRT1261227	hsa-miR-650	CLIP-seq
MIRT1261228	hsa-miR-657	CLIP-seq
MIRT2076835	hsa-miR-661	CLIP-seq
MIRT1261229	hsa-miR-663b	CLIP-seq
MIRT1261230	hsa-miR-671-5p	CLIP-seq
MIRT1261232	hsa-miR-761	CLIP-seq
MIRT2076836	hsa-miR-764	CLIP-seq
MIRT1261234	hsa-miR-765	CLIP-seq
MIRT2076837	hsa-miR-766	CLIP-seq
MIRT1261235	hsa-miR-93	CLIP-seq
MIRT1261056	hsa-miR-1	CLIP-seq
MIRT1261057	hsa-miR-106a	CLIP-seq
MIRT1261058	hsa-miR-106b	CLIP-seq
MIRT1261059	hsa-miR-1207-5p	CLIP-seq
MIRT1261061	hsa-miR-1237	CLIP-seq
MIRT1261062	hsa-miR-1252	CLIP-seq
MIRT2303496	hsa-miR-125a-5p	CLIP-seq
MIRT2303497	hsa-miR-125b	CLIP-seq
MIRT1261064	hsa-miR-1264	CLIP-seq
MIRT1261066	hsa-miR-1267	CLIP-seq
MIRT2303498	hsa-miR-1275	CLIP-seq
MIRT2303499	hsa-miR-128	CLIP-seq
MIRT2303500	hsa-miR-1321	CLIP-seq
MIRT2303501	hsa-miR-1323	CLIP-seq
MIRT1261067	hsa-miR-133a	CLIP-seq
MIRT1261068	hsa-miR-133b	CLIP-seq
MIRT1261069	hsa-miR-138	CLIP-seq
MIRT1261070	hsa-miR-142-5p	CLIP-seq
MIRT1261073	hsa-miR-148a	CLIP-seq
MIRT1261074	hsa-miR-148b	CLIP-seq
MIRT1261075	hsa-miR-149	CLIP-seq
MIRT2303502	hsa-miR-150	CLIP-seq
MIRT1261076	hsa-miR-152	CLIP-seq
MIRT1261077	hsa-miR-17	CLIP-seq
MIRT1261078	hsa-miR-1825	CLIP-seq
MIRT1261079	hsa-miR-1827	CLIP-seq
MIRT1261080	hsa-miR-1914	CLIP-seq
MIRT1261081	hsa-miR-1915	CLIP-seq
MIRT2303503	hsa-miR-193a-5p	CLIP-seq
MIRT1261082	hsa-miR-194	CLIP-seq
MIRT1261084	hsa-miR-198	CLIP-seq
MIRT1261085	hsa-miR-203	CLIP-seq
MIRT1261087	hsa-miR-206	CLIP-seq
MIRT1261088	hsa-miR-20a	CLIP-seq
MIRT1261089	hsa-miR-20b	CLIP-seq
MIRT1261091	hsa-miR-214	CLIP-seq
MIRT1261092	hsa-miR-2355-5p	CLIP-seq
MIRT2303504	hsa-miR-27a	CLIP-seq
MIRT2303505	hsa-miR-27b	CLIP-seq
MIRT1261093	hsa-miR-2964a-5p	CLIP-seq
MIRT1261094	hsa-miR-3064-5p	CLIP-seq
MIRT2076785	hsa-miR-3065-3p	CLIP-seq
MIRT2076786	hsa-miR-3065-5p	CLIP-seq
MIRT2303506	hsa-miR-3115	CLIP-seq
MIRT2076787	hsa-miR-3128	CLIP-seq
MIRT1261095	hsa-miR-3134	CLIP-seq
MIRT2303507	hsa-miR-3135b	CLIP-seq
MIRT1261096	hsa-miR-3138	CLIP-seq
MIRT1261097	hsa-miR-3150b-3p	CLIP-seq
MIRT2076790	hsa-miR-3151	CLIP-seq
MIRT1261098	hsa-miR-3157-5p	CLIP-seq
MIRT1261099	hsa-miR-3173-3p	CLIP-seq
MIRT1261100	hsa-miR-3180	CLIP-seq
MIRT1261101	hsa-miR-3180-3p	CLIP-seq
MIRT1261102	hsa-miR-3182	CLIP-seq
MIRT1261103	hsa-miR-3185	CLIP-seq
MIRT1261106	hsa-miR-3194-3p	CLIP-seq
MIRT1261107	hsa-miR-3196	CLIP-seq
MIRT1261108	hsa-miR-320e	CLIP-seq
MIRT1261109	hsa-miR-331-3p	CLIP-seq
MIRT2303508	hsa-miR-338-3p	CLIP-seq
MIRT2076794	hsa-miR-3591-3p	CLIP-seq
MIRT1261111	hsa-miR-3611	CLIP-seq
MIRT1261112	hsa-miR-3612	CLIP-seq
MIRT2076795	hsa-miR-3613-3p	CLIP-seq
MIRT1261113	hsa-miR-3615	CLIP-seq
MIRT1261114	hsa-miR-3619-5p	CLIP-seq
MIRT1261115	hsa-miR-3622a-3p	CLIP-seq
MIRT1261116	hsa-miR-3622b-3p	CLIP-seq
MIRT2303509	hsa-miR-3648	CLIP-seq
MIRT1261117	hsa-miR-3650	CLIP-seq
MIRT1261118	hsa-miR-3652	CLIP-seq
MIRT1261119	hsa-miR-3662	CLIP-seq
MIRT1261122	hsa-miR-3673	CLIP-seq
MIRT1261123	hsa-miR-3691-3p	CLIP-seq
MIRT2303510	hsa-miR-371b-5p	CLIP-seq
MIRT1261125	hsa-miR-3910	CLIP-seq
MIRT1261127	hsa-miR-3918	CLIP-seq
MIRT2303511	hsa-miR-3925-3p	CLIP-seq
MIRT1261128	hsa-miR-3937	CLIP-seq
MIRT2303512	hsa-miR-411	CLIP-seq
MIRT1261131	hsa-miR-4267	CLIP-seq
MIRT2076800	hsa-miR-4270	CLIP-seq
MIRT2303513	hsa-miR-4271	CLIP-seq
MIRT1261133	hsa-miR-4281	CLIP-seq
MIRT1261134	hsa-miR-4299	CLIP-seq
MIRT2303514	hsa-miR-4319	CLIP-seq
MIRT1261136	hsa-miR-4426	CLIP-seq
MIRT1261137	hsa-miR-4430	CLIP-seq
MIRT2303515	hsa-miR-4434	CLIP-seq
MIRT2303516	hsa-miR-4435	CLIP-seq
MIRT2076805	hsa-miR-4441	CLIP-seq
MIRT2076806	hsa-miR-4443	CLIP-seq
MIRT1261138	hsa-miR-4446-3p	CLIP-seq
MIRT2303517	hsa-miR-4446-5p	CLIP-seq
MIRT2303518	hsa-miR-4447	CLIP-seq
MIRT1261139	hsa-miR-4449	CLIP-seq
MIRT1261140	hsa-miR-4456	CLIP-seq
MIRT2303519	hsa-miR-4472	CLIP-seq
MIRT1261141	hsa-miR-4474-3p	CLIP-seq
MIRT1261142	hsa-miR-4480	CLIP-seq
MIRT1261143	hsa-miR-4487	CLIP-seq
MIRT1261144	hsa-miR-4490	CLIP-seq
MIRT1261145	hsa-miR-4491	CLIP-seq
MIRT1261146	hsa-miR-4492	CLIP-seq
MIRT1261147	hsa-miR-4493	CLIP-seq
MIRT1261148	hsa-miR-4495	CLIP-seq
MIRT1261149	hsa-miR-4496	CLIP-seq
MIRT1261150	hsa-miR-4498	CLIP-seq
MIRT1261151	hsa-miR-4505	CLIP-seq
MIRT1261154	hsa-miR-4514	CLIP-seq
MIRT2303520	hsa-miR-4516	CLIP-seq
MIRT2303521	hsa-miR-4525	CLIP-seq
MIRT1261156	hsa-miR-4530	CLIP-seq
MIRT2303522	hsa-miR-4531	CLIP-seq
MIRT1261157	hsa-miR-4533	CLIP-seq
MIRT1261158	hsa-miR-4534	CLIP-seq
MIRT1261160	hsa-miR-4646-3p	CLIP-seq
MIRT1261161	hsa-miR-4647	CLIP-seq
MIRT1261163	hsa-miR-4652-3p	CLIP-seq
MIRT1261165	hsa-miR-4657	CLIP-seq
MIRT1261166	hsa-miR-4662b	CLIP-seq
MIRT2303523	hsa-miR-4665-5p	CLIP-seq
MIRT2076812	hsa-miR-4668-3p	CLIP-seq
MIRT1261169	hsa-miR-4685-5p	CLIP-seq
MIRT1261170	hsa-miR-4689	CLIP-seq
MIRT1261171	hsa-miR-4690-5p	CLIP-seq
MIRT1261172	hsa-miR-4691-3p	CLIP-seq
MIRT1261173	hsa-miR-4692	CLIP-seq
MIRT1261174	hsa-miR-4695-5p	CLIP-seq
MIRT1261176	hsa-miR-4713-3p	CLIP-seq
MIRT2076815	hsa-miR-4720-5p	CLIP-seq
MIRT2303524	hsa-miR-4723-5p	CLIP-seq
MIRT1261177	hsa-miR-4724-3p	CLIP-seq
MIRT2303525	hsa-miR-4725-3p	CLIP-seq
MIRT1261178	hsa-miR-4731-5p	CLIP-seq
MIRT2303526	hsa-miR-4732-3p	CLIP-seq
MIRT2076820	hsa-miR-4733-5p	CLIP-seq
MIRT2076821	hsa-miR-4736	CLIP-seq
MIRT2303527	hsa-miR-4739	CLIP-seq
MIRT2303528	hsa-miR-4747-5p	CLIP-seq
MIRT1261181	hsa-miR-4755-3p	CLIP-seq
MIRT1261182	hsa-miR-4755-5p	CLIP-seq
MIRT2076822	hsa-miR-4756-3p	CLIP-seq
MIRT2303529	hsa-miR-4756-5p	CLIP-seq
MIRT1261183	hsa-miR-4757-3p	CLIP-seq
MIRT1261184	hsa-miR-4757-5p	CLIP-seq
MIRT1261185	hsa-miR-4762-5p	CLIP-seq
MIRT1261186	hsa-miR-4763-3p	CLIP-seq
MIRT1261187	hsa-miR-4774-5p	CLIP-seq
MIRT2303530	hsa-miR-4777-3p	CLIP-seq
MIRT1261189	hsa-miR-4784	CLIP-seq
MIRT1261190	hsa-miR-4794	CLIP-seq
MIRT2076824	hsa-miR-4799-3p	CLIP-seq
MIRT1261191	hsa-miR-4800-5p	CLIP-seq
MIRT1261192	hsa-miR-4802-5p	CLIP-seq
MIRT2076825	hsa-miR-486-3p	CLIP-seq
MIRT1261193	hsa-miR-490-3p	CLIP-seq
MIRT2076826	hsa-miR-495	CLIP-seq
MIRT2303531	hsa-miR-514	CLIP-seq
MIRT2303532	hsa-miR-514b-3p	CLIP-seq
MIRT1261194	hsa-miR-516a-3p	CLIP-seq
MIRT1261195	hsa-miR-519a	CLIP-seq
MIRT1261196	hsa-miR-519b-3p	CLIP-seq
MIRT1261197	hsa-miR-519c-3p	CLIP-seq
MIRT1261198	hsa-miR-519d	CLIP-seq
MIRT1261199	hsa-miR-520a-5p	CLIP-seq
MIRT1261200	hsa-miR-525-5p	CLIP-seq
MIRT1261201	hsa-miR-542-5p	CLIP-seq
MIRT1261202	hsa-miR-548a-5p	CLIP-seq
MIRT1261203	hsa-miR-548ab	CLIP-seq
MIRT2303533	hsa-miR-548ad	CLIP-seq
MIRT1261204	hsa-miR-548ak	CLIP-seq
MIRT1261205	hsa-miR-548b-5p	CLIP-seq
MIRT1261206	hsa-miR-548c-3p	CLIP-seq
MIRT1261207	hsa-miR-548c-5p	CLIP-seq
MIRT1261208	hsa-miR-548d-5p	CLIP-seq
MIRT1261210	hsa-miR-548h	CLIP-seq
MIRT1261211	hsa-miR-548i	CLIP-seq
MIRT1261212	hsa-miR-548j	CLIP-seq
MIRT1261213	hsa-miR-548k	CLIP-seq
MIRT1261214	hsa-miR-548l	CLIP-seq
MIRT2303534	hsa-miR-548o	CLIP-seq
MIRT1261215	hsa-miR-548t	CLIP-seq
MIRT1261216	hsa-miR-548w	CLIP-seq
MIRT1261217	hsa-miR-548y	CLIP-seq
MIRT2303535	hsa-miR-549	CLIP-seq
MIRT1261218	hsa-miR-559	CLIP-seq
MIRT2076834	hsa-miR-605	CLIP-seq
MIRT1261221	hsa-miR-607	CLIP-seq
MIRT1261222	hsa-miR-613	CLIP-seq
MIRT1261223	hsa-miR-619	CLIP-seq
MIRT2303536	hsa-miR-625	CLIP-seq
MIRT1261225	hsa-miR-637	CLIP-seq
MIRT1261226	hsa-miR-644	CLIP-seq
MIRT1261227	hsa-miR-650	CLIP-seq
MIRT1261228	hsa-miR-657	CLIP-seq
MIRT1261229	hsa-miR-663b	CLIP-seq
MIRT2303537	hsa-miR-670	CLIP-seq
MIRT1261230	hsa-miR-671-5p	CLIP-seq
MIRT1261231	hsa-miR-760	CLIP-seq
MIRT1261232	hsa-miR-761	CLIP-seq
MIRT1261233	hsa-miR-762	CLIP-seq
MIRT1261234	hsa-miR-765	CLIP-seq
MIRT2076837	hsa-miR-766	CLIP-seq
MIRT2303538	hsa-miR-873	CLIP-seq
MIRT2303539	hsa-miR-875-5p	CLIP-seq
MIRT1261235	hsa-miR-93	CLIP-seq
MIRT1261236	hsa-miR-940	CLIP-seq
MIRT1261069	hsa-miR-138	CLIP-seq
MIRT2392955	hsa-miR-4529-5p	CLIP-seq
MIRT1261223	hsa-miR-619	CLIP-seq
MIRT1261091	hsa-miR-214	CLIP-seq
MIRT2076786	hsa-miR-3065-5p	CLIP-seq
MIRT2076794	hsa-miR-3591-3p	CLIP-seq
MIRT2076795	hsa-miR-3613-3p	CLIP-seq
MIRT1261114	hsa-miR-3619-5p	CLIP-seq
MIRT2457141	hsa-miR-3621	CLIP-seq
MIRT2076812	hsa-miR-4668-3p	CLIP-seq
MIRT2076820	hsa-miR-4733-5p	CLIP-seq
MIRT2076828	hsa-miR-518a-3p	CLIP-seq
MIRT2076829	hsa-miR-518b	CLIP-seq
MIRT2076830	hsa-miR-518c	CLIP-seq
MIRT2076831	hsa-miR-518d-3p	CLIP-seq
MIRT2076832	hsa-miR-518f	CLIP-seq
MIRT1261206	hsa-miR-548c-3p	CLIP-seq
MIRT2076834	hsa-miR-605	CLIP-seq
MIRT1261232	hsa-miR-761	CLIP-seq
MIRT2076786	hsa-miR-3065-5p	CLIP-seq
MIRT2076794	hsa-miR-3591-3p	CLIP-seq
MIRT2076795	hsa-miR-3613-3p	CLIP-seq
MIRT2076812	hsa-miR-4668-3p	CLIP-seq
MIRT2076820	hsa-miR-4733-5p	CLIP-seq
MIRT1261206	hsa-miR-548c-3p	CLIP-seq
MIRT2076834	hsa-miR-605	CLIP-seq
MIRT1261091	hsa-miR-214	CLIP-seq
MIRT1261114	hsa-miR-3619-5p	CLIP-seq
MIRT2457141	hsa-miR-3621	CLIP-seq
MIRT2076828	hsa-miR-518a-3p	CLIP-seq
MIRT2076829	hsa-miR-518b	CLIP-seq
MIRT2076830	hsa-miR-518c	CLIP-seq
MIRT2076831	hsa-miR-518d-3p	CLIP-seq
MIRT2076832	hsa-miR-518f	CLIP-seq
MIRT1261232	hsa-miR-761	CLIP-seq
MIRT1261059	hsa-miR-1207-5p	CLIP-seq
MIRT1261091	hsa-miR-214	CLIP-seq
MIRT2076787	hsa-miR-3128	CLIP-seq
MIRT1261114	hsa-miR-3619-5p	CLIP-seq
MIRT2457141	hsa-miR-3621	CLIP-seq
MIRT1261131	hsa-miR-4267	CLIP-seq
MIRT2076815	hsa-miR-4720-5p	CLIP-seq
MIRT2076821	hsa-miR-4736	CLIP-seq
MIRT1261186	hsa-miR-4763-3p	CLIP-seq
MIRT2076824	hsa-miR-4799-3p	CLIP-seq
MIRT2076828	hsa-miR-518a-3p	CLIP-seq
MIRT2076829	hsa-miR-518b	CLIP-seq
MIRT2076830	hsa-miR-518c	CLIP-seq
MIRT2076831	hsa-miR-518d-3p	CLIP-seq
MIRT2076832	hsa-miR-518f	CLIP-seq
MIRT1261232	hsa-miR-761	CLIP-seq
MIRT2076837	hsa-miR-766	CLIP-seq

Show/Hide all(39)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IBA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	TAS	12123595
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	TAS	12123595
GO:0005515	Function	Protein binding	IPI	17565979, 21339740, 27150042, 33061433
GO:0005543	Function	Phospholipid binding	IDA	11955434
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA	11955434
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	12123595
GO:0006801	Process	Superoxide metabolic process	TAS	12123595
GO:0007186	Process	G protein-coupled receptor signaling pathway	IBA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0016020	Component	Membrane	IEA
GO:0019899	Function	Enzyme binding	TAS	12123595
GO:0030041	Process	Actin filament polymerization	TAS	12123595
GO:0030217	Process	T cell differentiation	IEA
GO:0030291	Function	Protein serine/threonine kinase inhibitor activity	IBA
GO:0030335	Process	Positive regulation of cell migration	IEA
GO:0030426	Component	Growth cone	IEA
GO:0030593	Process	Neutrophil chemotaxis	IEA
GO:0030833	Process	Regulation of actin filament polymerization	IEA
GO:0032007	Process	Negative regulation of TOR signaling	IBA
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0042119	Process	Neutrophil activation	TAS	12123595
GO:0043198	Component	Dendritic shaft	IEA
GO:0045321	Process	Leukocyte activation	IEA
GO:0045785	Process	Positive regulation of cell adhesion	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0050773	Process	Regulation of dendrite development	IEA
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	IEA
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS
GO:0072593	Process	Reactive oxygen species metabolic process	IEA
GO:0072593	Process	Reactive oxygen species metabolic process	IEA
GO:1900026	Process	Positive regulation of substrate adhesion-dependent cell spreading	IEA

MIM	HGNC	e!Ensembl
606905	32594	ENSG00000124126

Protein

UniProt ID

Q8TCU6

Protein name

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)

Protein function

Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits

PDB

3QIK , 4YON , 5D27 , 5D3V , 5D3W , 5D3X , 5D3Y , 5FI0 , 5FI1 , 6PCV , 6VSK , 7RX9 , 8TUA

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00621	RhoGEF	53 → 238	RhoGEF domain	Domain
PF00610	DEP	426 → 494	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	Domain
PF00610	DEP	527 → 595	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	Domain

Tissue specificity

TISSUE SPECIFICITY: Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.

Sequence

MEAPSGSEPGGDGAGDCAHPDPRAPGAAAPSSGPGPCAAARESERQLRLRLCVLNEILGT
ERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAALEYC
LHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKIPTVRAFLLSCMLLGG
RKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCSNINET
KRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVY
CKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWK
IHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYVMIAEKGEKLYHMM
MNKKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVS
DKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYTPVIKDRDYHLKTYK
SVLPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFRDESQYFRFHADEE
MEGTSSKNKQLRNDFKLVENILAKRLLILPQEEDYGFDIEEKNKAVVVKSVQRGSLAEVA
GLQVGRKIYSINEDLVFLRPFSEVESILNQSFCSRRPLRLLVATKAKEIIKIPDQPDTLC
FQIRGAAPPYVYAVGRGSEAMAAGLCAGQCILKVNGSNVMNDGAPEVLEHFQAFRSRREE
ALGLYQWIYHTHEDAQEARASQEASTEDPSGEQAQEEDQADSAFPLLSLGPRLSLCEDSP
MVTLTVDNVHLEHGVVYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFVEN
CRRLMALSSAIVTMPHFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEPH
PLCGLDFCPTNCHINLMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQGHLNPMSYTQH
CITTMAAPSWKCLPAAEGDPQGQGLHDGSFGPASGTLGQEDRGLSFLLKQEDREIQDAYL
QLFTKLDVALKEMKQYVTQINRLLSTITEPTSGGSCDASLAEEASSLPLVSEESEMDRSD
HGGIKKVCFKVAEEDQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDEMGS
GDELPCDMRIPSDKQDKLHGCLEHLFNQVDSINALLKGPVMSRAFEETKHFPMNHSLQEF
KQKEECTIRGRSLIQISIQEDPWNLPNSIKTLVDNIQRYVEDGKNQLLLALLKCTDTELQ
LRRDAIFCQALVAAVCTFSKQLLAALGYRYNNNGEYEESSRDASRKWLEQVAATGVLLHC
QSLLSPATVKEERTMLEDIWVTLSELDNVTFSFKQLDENYVANTNVFYHIEGSRQALKVI
FYLDSYHFSKLPSRLEGGASLRLHTALFTKVLENVEGLPSPGSQAAEDLQQDINAQSLEK
VQQYYRKLRAFYLERSNLPTDASTTAVKIDQLIRPINALDELCRLMKSFVHPKPGAAGSV
GAGLIPISSELCYRLGACQMVMCGTGMQRSTLSVSLEQAAILARSHGLLPKCIMQATDIM
RKQGPRVEILAKNLRVKDQMPQGAPRLYRLCQPPVDGDL

Sequence length

1659

Interactions

View interactions

	KEGG		Reactome
	Chemokine signaling pathway Kaposi sarcoma-associated herpesvirus infection		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events

Show/Hide Unknown Diseases (11)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Colorectal Cancer	Early onset colorectal cancer, Colorectal cancer	N/A	N/A	GWAS
Coronary artery disease	Coronary artery disease	N/A	N/A	GWAS
Hypertension	Hypertension, Hypertension (confirmatory factor analysis Factor 12), ICD10 O13: Gestational hypertension, Gestational hypertension	N/A	N/A	GWAS
Hypothyroidism	Hypothyroidism	N/A	N/A	GWAS
Multiple myeloma	Multiple myeloma	N/A	N/A	GWAS
Myocardial Infarction	Myocardial infarction	N/A	N/A	GWAS
Otosclerosis	Otosclerosis	N/A	N/A	GWAS
Psoriasis	Psoriasis	N/A	N/A	GWAS
Rheumatoid arthritis	Rheumatoid arthritis	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (20)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Breast Neoplasms	Associate	21172654, 25248717, 27185877, 27351228, 31372638, 31473760
Carcinogenesis	Associate	21172654
Carcinoma Non Small Cell Lung	Inhibit	34783629
Colorectal Neoplasms	Associate	35213358, 37749132
Diabetes Mellitus Type 2	Associate	18602983, 20650312
Glioblastoma	Associate	28051998, 29903919
Inflammation	Inhibit	27173636
Kidney Failure Chronic	Associate	18602983
Lupus Erythematosus Systemic	Associate	21436623
Melanoma	Associate	23382862
Monoclonal Gammopathy of Undetermined Significance	Associate	30134812
Multiple Myeloma	Associate	30134812, 35013207
Neoplasm Metastasis	Associate	23382862, 31473760, 37434402
Neoplasms	Associate	23382862, 30134812, 31473760, 31933512
Neoplasms Adipose Tissue	Associate	20650312
Osteoarthritis Knee	Associate	37817257
Phenylketonurias	Associate	39337507
Pulmonary Fibrosis	Associate	27173636
Stomach Neoplasms	Associate	31933512, 37434402
Triple Negative Breast Neoplasms	Associate	36693952

PREX1 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1)