PTMA (prothymosin alpha)

Gene
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
5757
Gene name Gene Name - the full gene name approved by the HGNC.
Prothymosin alpha
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PTMA
Synonyms (NCBI Gene) Gene synonyms aliases
TMSA
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q37.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Show/Hide all(1021)
miRTarBase ID miRNA Experiments Reference
MIRT001343 hsa-miR-1-3p pSILAC 18668040
MIRT001343 hsa-miR-1-3p Immunoblot, Immunofluorescence, Immunoprecipitaion, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 22210864
MIRT001343 hsa-miR-1-3p Immunoblot, Immunofluorescence, Immunoprecipitaion, Luciferase reporter assay, Microarray, qRT-PCR, Western blot 22210864
MIRT001343 hsa-miR-1-3p Luciferase reporter assay 22059741
MIRT001343 hsa-miR-1-3p Luciferase reporter assay 22059741
Transcription factors
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Show/Hide all(1)
Transcription factor Regulation Reference
ESR1 Repression 12149645
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
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GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 15607035, 16478804, 21044950, 25556234
GO:0005634 Component Nucleus IDA 8485135, 11897665
GO:0005654 Component Nucleoplasm IDA
GO:0005829 Component Cytosol IDA
GO:0006351 Process Transcription, DNA-templated TAS 10854063
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
188390 9623 ENSG00000187514
Protein
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
UniProt ID P06454
Protein name Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]
Protein function Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
PDB 2L9I , 2MNQ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03247 Prothymosin 2 → 110 Prothymosin/parathymosin family Family
Sequence
Sequence length 111
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 10822126
Rhabdomyosarcoma Rhabdomyosarcoma rs137854557, rs121909224, rs63751466, rs11540652, rs28934874, rs104894229, rs104894230, rs267606708, rs80357867, rs276174889, rs80359011, rs80358556, rs80359391, rs80357989, rs886037650
View all (19 more)		 16669873
Show/Hide Text Mining Associations (13)
Associations from Text Mining
Disease Name Relationship Type References
Carcinogenesis Associate 25197357
Carcinoma Hepatocellular Associate 26517516
Colorectal Neoplasms Associate 25197357
Dermatomyositis Associate 36742332
Glioma Associate 35297481
Lymphatic Metastasis Stimulate 25197357
Neoplasm Metastasis Stimulate 25197357
Neoplasms Associate 25197357, 27892895, 35297481
Neuroendocrine Tumors Associate 36686485
Osteoporosis Associate 22957024, 23367184