Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	57569
Gene name Gene Name - the full gene name approved by the HGNC.	Rho GTPase activating protein 20
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ARHGAP20
Synonyms (NCBI Gene) Gene synonyms aliases	RARHOGAP
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11q22.3-q23.1
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. [provided by RefSeq, Sep 2016]

Show/Hide all(266)

miRTarBase ID	miRNA	Experiments
MIRT794051	hsa-miR-1303	CLIP-seq
MIRT794052	hsa-miR-1324	CLIP-seq
MIRT794053	hsa-miR-148a	CLIP-seq
MIRT794054	hsa-miR-148b	CLIP-seq
MIRT794055	hsa-miR-152	CLIP-seq
MIRT794056	hsa-miR-23a	CLIP-seq
MIRT794057	hsa-miR-23b	CLIP-seq
MIRT794058	hsa-miR-23c	CLIP-seq
MIRT794059	hsa-miR-3123	CLIP-seq
MIRT794060	hsa-miR-3925-5p	CLIP-seq
MIRT794061	hsa-miR-4310	CLIP-seq
MIRT794062	hsa-miR-4312	CLIP-seq
MIRT794063	hsa-miR-4422	CLIP-seq
MIRT794064	hsa-miR-4659a-3p	CLIP-seq
MIRT794065	hsa-miR-4659b-3p	CLIP-seq
MIRT794066	hsa-miR-4711-5p	CLIP-seq
MIRT794067	hsa-miR-4778-3p	CLIP-seq
MIRT794068	hsa-miR-515-3p	CLIP-seq
MIRT794069	hsa-miR-519e	CLIP-seq
MIRT794070	hsa-miR-548aa	CLIP-seq
MIRT794071	hsa-miR-570	CLIP-seq
MIRT794072	hsa-miR-577	CLIP-seq
MIRT794073	hsa-miR-599	CLIP-seq
MIRT794074	hsa-miR-622	CLIP-seq
MIRT794075	hsa-miR-656	CLIP-seq
MIRT1934309	hsa-miR-150	CLIP-seq
MIRT1934310	hsa-miR-216a	CLIP-seq
MIRT1934311	hsa-miR-3163	CLIP-seq
MIRT1934311	hsa-miR-3163	CLIP-seq
MIRT2435453	hsa-miR-1266	CLIP-seq
MIRT2435454	hsa-miR-1289	CLIP-seq
MIRT2435455	hsa-miR-199a-3p	CLIP-seq
MIRT2435456	hsa-miR-199b-3p	CLIP-seq
MIRT2435457	hsa-miR-2114	CLIP-seq
MIRT1934310	hsa-miR-216a	CLIP-seq
MIRT2435458	hsa-miR-3129-5p	CLIP-seq
MIRT2435459	hsa-miR-3153	CLIP-seq
MIRT2435460	hsa-miR-3157-3p	CLIP-seq
MIRT2435461	hsa-miR-342-3p	CLIP-seq
MIRT2435462	hsa-miR-3664-3p	CLIP-seq
MIRT2435463	hsa-miR-370	CLIP-seq
MIRT2435464	hsa-miR-3913-3p	CLIP-seq
MIRT2435465	hsa-miR-4436a	CLIP-seq
MIRT2435466	hsa-miR-4475	CLIP-seq
MIRT2435467	hsa-miR-4518	CLIP-seq
MIRT2435468	hsa-miR-4645-3p	CLIP-seq
MIRT2435469	hsa-miR-628-5p	CLIP-seq
MIRT2435470	hsa-miR-942	CLIP-seq
MIRT2477712	hsa-miR-106a	CLIP-seq
MIRT2477713	hsa-miR-106b	CLIP-seq
MIRT2477714	hsa-miR-1264	CLIP-seq
MIRT2477715	hsa-miR-1276	CLIP-seq
MIRT2435454	hsa-miR-1289	CLIP-seq
MIRT2477716	hsa-miR-1297	CLIP-seq
MIRT2477717	hsa-miR-1299	CLIP-seq
MIRT794051	hsa-miR-1303	CLIP-seq
MIRT2477718	hsa-miR-142-5p	CLIP-seq
MIRT794053	hsa-miR-148a	CLIP-seq
MIRT794054	hsa-miR-148b	CLIP-seq
MIRT1934309	hsa-miR-150	CLIP-seq
MIRT794055	hsa-miR-152	CLIP-seq
MIRT2477719	hsa-miR-15a	CLIP-seq
MIRT2477720	hsa-miR-15b	CLIP-seq
MIRT2477721	hsa-miR-16	CLIP-seq
MIRT2477722	hsa-miR-17	CLIP-seq
MIRT2477723	hsa-miR-190	CLIP-seq
MIRT2477724	hsa-miR-190b	CLIP-seq
MIRT2477725	hsa-miR-1915	CLIP-seq
MIRT2477726	hsa-miR-195	CLIP-seq
MIRT2435455	hsa-miR-199a-3p	CLIP-seq
MIRT2435456	hsa-miR-199b-3p	CLIP-seq
MIRT2477727	hsa-miR-20a	CLIP-seq
MIRT2477728	hsa-miR-20b	CLIP-seq
MIRT2435457	hsa-miR-2114	CLIP-seq
MIRT2477729	hsa-miR-2276	CLIP-seq
MIRT2477730	hsa-miR-2355-3p	CLIP-seq
MIRT2477731	hsa-miR-26a	CLIP-seq
MIRT2477732	hsa-miR-26b	CLIP-seq
MIRT2477733	hsa-miR-300	CLIP-seq
MIRT2477734	hsa-miR-3117-3p	CLIP-seq
MIRT794059	hsa-miR-3123	CLIP-seq
MIRT2435458	hsa-miR-3129-5p	CLIP-seq
MIRT2477735	hsa-miR-3133	CLIP-seq
MIRT2477736	hsa-miR-3144-3p	CLIP-seq
MIRT2477737	hsa-miR-3146	CLIP-seq
MIRT2435459	hsa-miR-3153	CLIP-seq
MIRT2435460	hsa-miR-3157-3p	CLIP-seq
MIRT2477738	hsa-miR-3169	CLIP-seq
MIRT2477739	hsa-miR-340	CLIP-seq
MIRT2477740	hsa-miR-3609	CLIP-seq
MIRT2477741	hsa-miR-3613-3p	CLIP-seq
MIRT2477742	hsa-miR-361-5p	CLIP-seq
MIRT2477743	hsa-miR-3617	CLIP-seq
MIRT2477744	hsa-miR-3647-3p	CLIP-seq
MIRT2477745	hsa-miR-3668	CLIP-seq
MIRT2477746	hsa-miR-3673	CLIP-seq
MIRT2477747	hsa-miR-3688-3p	CLIP-seq
MIRT2435463	hsa-miR-370	CLIP-seq
MIRT2477748	hsa-miR-381	CLIP-seq
MIRT2477749	hsa-miR-3908	CLIP-seq
MIRT794060	hsa-miR-3925-5p	CLIP-seq
MIRT2477750	hsa-miR-3936	CLIP-seq
MIRT2477751	hsa-miR-3942-5p	CLIP-seq
MIRT2477752	hsa-miR-424	CLIP-seq
MIRT2477753	hsa-miR-4260	CLIP-seq
MIRT2477754	hsa-miR-4282	CLIP-seq
MIRT2477755	hsa-miR-4299	CLIP-seq
MIRT2477756	hsa-miR-4311	CLIP-seq
MIRT794062	hsa-miR-4312	CLIP-seq
MIRT2477757	hsa-miR-4453	CLIP-seq
MIRT2477758	hsa-miR-4456	CLIP-seq
MIRT2477759	hsa-miR-4465	CLIP-seq
MIRT2477760	hsa-miR-4474-5p	CLIP-seq
MIRT2435466	hsa-miR-4475	CLIP-seq
MIRT2477761	hsa-miR-448	CLIP-seq
MIRT2477762	hsa-miR-4515	CLIP-seq
MIRT2477763	hsa-miR-4517	CLIP-seq
MIRT2477764	hsa-miR-4524	CLIP-seq
MIRT2477765	hsa-miR-4538	CLIP-seq
MIRT2435468	hsa-miR-4645-3p	CLIP-seq
MIRT794064	hsa-miR-4659a-3p	CLIP-seq
MIRT794065	hsa-miR-4659b-3p	CLIP-seq
MIRT2477766	hsa-miR-4666-3p	CLIP-seq
MIRT2477767	hsa-miR-4703-5p	CLIP-seq
MIRT2477768	hsa-miR-4713-5p	CLIP-seq
MIRT2477769	hsa-miR-4726-3p	CLIP-seq
MIRT2477770	hsa-miR-4759	CLIP-seq
MIRT2477771	hsa-miR-4766-3p	CLIP-seq
MIRT2477772	hsa-miR-4772-3p	CLIP-seq
MIRT2477773	hsa-miR-4773	CLIP-seq
MIRT794067	hsa-miR-4778-3p	CLIP-seq
MIRT2477774	hsa-miR-4789-5p	CLIP-seq
MIRT2477775	hsa-miR-4796-3p	CLIP-seq
MIRT2477776	hsa-miR-485-3p	CLIP-seq
MIRT2477777	hsa-miR-486-3p	CLIP-seq
MIRT2477778	hsa-miR-494	CLIP-seq
MIRT2477779	hsa-miR-497	CLIP-seq
MIRT2477780	hsa-miR-500a	CLIP-seq
MIRT2477781	hsa-miR-503	CLIP-seq
MIRT794068	hsa-miR-515-3p	CLIP-seq
MIRT2477782	hsa-miR-519d	CLIP-seq
MIRT794069	hsa-miR-519e	CLIP-seq
MIRT2477783	hsa-miR-520d-5p	CLIP-seq
MIRT2477784	hsa-miR-524-5p	CLIP-seq
MIRT2477785	hsa-miR-532-3p	CLIP-seq
MIRT2477786	hsa-miR-544	CLIP-seq
MIRT2477787	hsa-miR-548a-5p	CLIP-seq
MIRT794070	hsa-miR-548aa	CLIP-seq
MIRT2477788	hsa-miR-548ab	CLIP-seq
MIRT2477789	hsa-miR-548ah	CLIP-seq
MIRT2477790	hsa-miR-548ak	CLIP-seq
MIRT2477791	hsa-miR-548b-5p	CLIP-seq
MIRT2477792	hsa-miR-548c-5p	CLIP-seq
MIRT2477793	hsa-miR-548d-5p	CLIP-seq
MIRT2477794	hsa-miR-548h	CLIP-seq
MIRT2477795	hsa-miR-548i	CLIP-seq
MIRT2477796	hsa-miR-548j	CLIP-seq
MIRT2477797	hsa-miR-548k	CLIP-seq
MIRT2477798	hsa-miR-548l	CLIP-seq
MIRT2477799	hsa-miR-548n	CLIP-seq
MIRT2477800	hsa-miR-548p	CLIP-seq
MIRT2477801	hsa-miR-548q	CLIP-seq
MIRT2477802	hsa-miR-548t	CLIP-seq
MIRT2477803	hsa-miR-548w	CLIP-seq
MIRT2477804	hsa-miR-548y	CLIP-seq
MIRT2477805	hsa-miR-559	CLIP-seq
MIRT794071	hsa-miR-570	CLIP-seq
MIRT2477806	hsa-miR-583	CLIP-seq
MIRT2477807	hsa-miR-591	CLIP-seq
MIRT2435469	hsa-miR-628-5p	CLIP-seq
MIRT2477808	hsa-miR-641	CLIP-seq
MIRT2477809	hsa-miR-646	CLIP-seq
MIRT794075	hsa-miR-656	CLIP-seq
MIRT2477810	hsa-miR-671-5p	CLIP-seq
MIRT2477811	hsa-miR-676	CLIP-seq
MIRT2477812	hsa-miR-875-3p	CLIP-seq
MIRT2477813	hsa-miR-885-5p	CLIP-seq
MIRT2477814	hsa-miR-889	CLIP-seq
MIRT2477815	hsa-miR-93	CLIP-seq
MIRT2477816	hsa-miR-944	CLIP-seq
MIRT2477714	hsa-miR-1264	CLIP-seq
MIRT2477715	hsa-miR-1276	CLIP-seq
MIRT2435454	hsa-miR-1289	CLIP-seq
MIRT2477716	hsa-miR-1297	CLIP-seq
MIRT2477718	hsa-miR-142-5p	CLIP-seq
MIRT794053	hsa-miR-148a	CLIP-seq
MIRT794054	hsa-miR-148b	CLIP-seq
MIRT794055	hsa-miR-152	CLIP-seq
MIRT2477723	hsa-miR-190	CLIP-seq
MIRT2477724	hsa-miR-190b	CLIP-seq
MIRT2435455	hsa-miR-199a-3p	CLIP-seq
MIRT2435456	hsa-miR-199b-3p	CLIP-seq
MIRT2435457	hsa-miR-2114	CLIP-seq
MIRT2477730	hsa-miR-2355-3p	CLIP-seq
MIRT2477731	hsa-miR-26a	CLIP-seq
MIRT2477732	hsa-miR-26b	CLIP-seq
MIRT2477734	hsa-miR-3117-3p	CLIP-seq
MIRT794059	hsa-miR-3123	CLIP-seq
MIRT2435458	hsa-miR-3129-5p	CLIP-seq
MIRT2477735	hsa-miR-3133	CLIP-seq
MIRT2477736	hsa-miR-3144-3p	CLIP-seq
MIRT2477737	hsa-miR-3146	CLIP-seq
MIRT2435459	hsa-miR-3153	CLIP-seq
MIRT2435460	hsa-miR-3157-3p	CLIP-seq
MIRT2477738	hsa-miR-3169	CLIP-seq
MIRT2477741	hsa-miR-3613-3p	CLIP-seq
MIRT2477742	hsa-miR-361-5p	CLIP-seq
MIRT2477743	hsa-miR-3617	CLIP-seq
MIRT2477744	hsa-miR-3647-3p	CLIP-seq
MIRT2477745	hsa-miR-3668	CLIP-seq
MIRT2477746	hsa-miR-3673	CLIP-seq
MIRT2477747	hsa-miR-3688-3p	CLIP-seq
MIRT2435463	hsa-miR-370	CLIP-seq
MIRT2477749	hsa-miR-3908	CLIP-seq
MIRT2477751	hsa-miR-3942-5p	CLIP-seq
MIRT2477753	hsa-miR-4260	CLIP-seq
MIRT2477754	hsa-miR-4282	CLIP-seq
MIRT2477755	hsa-miR-4299	CLIP-seq
MIRT2477756	hsa-miR-4311	CLIP-seq
MIRT794062	hsa-miR-4312	CLIP-seq
MIRT2477757	hsa-miR-4453	CLIP-seq
MIRT2477758	hsa-miR-4456	CLIP-seq
MIRT2477759	hsa-miR-4465	CLIP-seq
MIRT2477760	hsa-miR-4474-5p	CLIP-seq
MIRT2435466	hsa-miR-4475	CLIP-seq
MIRT2477761	hsa-miR-448	CLIP-seq
MIRT2477762	hsa-miR-4515	CLIP-seq
MIRT2477763	hsa-miR-4517	CLIP-seq
MIRT2477765	hsa-miR-4538	CLIP-seq
MIRT2435468	hsa-miR-4645-3p	CLIP-seq
MIRT2477767	hsa-miR-4703-5p	CLIP-seq
MIRT2477770	hsa-miR-4759	CLIP-seq
MIRT2477771	hsa-miR-4766-3p	CLIP-seq
MIRT2477773	hsa-miR-4773	CLIP-seq
MIRT2477776	hsa-miR-485-3p	CLIP-seq
MIRT2477777	hsa-miR-486-3p	CLIP-seq
MIRT2477778	hsa-miR-494	CLIP-seq
MIRT2477780	hsa-miR-500a	CLIP-seq
MIRT794068	hsa-miR-515-3p	CLIP-seq
MIRT794069	hsa-miR-519e	CLIP-seq
MIRT2477787	hsa-miR-548a-5p	CLIP-seq
MIRT794070	hsa-miR-548aa	CLIP-seq
MIRT2477788	hsa-miR-548ab	CLIP-seq
MIRT2477790	hsa-miR-548ak	CLIP-seq
MIRT2477791	hsa-miR-548b-5p	CLIP-seq
MIRT2477792	hsa-miR-548c-5p	CLIP-seq
MIRT2477793	hsa-miR-548d-5p	CLIP-seq
MIRT2477794	hsa-miR-548h	CLIP-seq
MIRT2477795	hsa-miR-548i	CLIP-seq
MIRT2477796	hsa-miR-548j	CLIP-seq
MIRT2477797	hsa-miR-548k	CLIP-seq
MIRT2477798	hsa-miR-548l	CLIP-seq
MIRT2477801	hsa-miR-548q	CLIP-seq
MIRT2477803	hsa-miR-548w	CLIP-seq
MIRT2477804	hsa-miR-548y	CLIP-seq
MIRT2477805	hsa-miR-559	CLIP-seq
MIRT794071	hsa-miR-570	CLIP-seq
MIRT2477806	hsa-miR-583	CLIP-seq
MIRT2477807	hsa-miR-591	CLIP-seq
MIRT2435469	hsa-miR-628-5p	CLIP-seq
MIRT2477808	hsa-miR-641	CLIP-seq
MIRT794075	hsa-miR-656	CLIP-seq
MIRT2477811	hsa-miR-676	CLIP-seq
MIRT2477813	hsa-miR-885-5p	CLIP-seq
MIRT2477814	hsa-miR-889	CLIP-seq
MIRT2477816	hsa-miR-944	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IEA
GO:0005096	Function	GTPase activator activity	TAS
GO:0005829	Component	Cytosol	TAS
GO:0007165	Process	Signal transduction	IEA
GO:0035023	Process	Regulation of Rho protein signal transduction	IEA
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	IEA
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS

MIM	HGNC	e!Ensembl
609568	18357	ENSG00000137727

Protein

UniProt ID

Q9P2F6

Protein name

Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20)

Protein function

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.

PDB

3MSX

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00788	RA	194 → 291	Ras association (RalGDS/AF-6) domain	Domain
PF00620	RhoGAP	377 → 527	RhoGAP domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed predominantly in the brain. Lower expression is found in lymph nodes. {ECO:0000269|PubMed:15543602}.

Sequence

MEAMSPQQETLGGQPGRSSSLTGVSRLAGGSCTKKKMKTLAERRRSAPSLILDKALQKRP
TTRDSPSASVDTCTFLSSLVCSNRTLLIDGRAELKRGLQRQERHLFLFNDLFVVAKIKYN
NNFKIKNKIKLTDMWTASCVDEVGEGNTNAMKSFVLGWPTVNFVATFSSPEQKDKWLSLL
QRYINLEKEKDYPKSIPLKIFAKDIGNCAYSKTITVMNSDTANEVINMSLPMLGITGSER
DYQLWVNSGKEEAPYPLIGHEYPYGIKMSHLRDSALLTPGSKDSTTPFNLQEPFLMEQLP
REMQCQFILKPSRLAAAQQLSDSGHKTFKRRRSIINWAFWRGSSTHLDNLPSSPTSPMPG
QLFGISLPNICENDNLPKPVLDMLFFLNQKGPLTKGIFRQSANVKSCRELKEKLNSGVEV
HLDCESIFVIASVLKDFLRNIPGSIFSSDLYDHWVSVMDQGNDEEKINTVQRLLDQLPRA
NVVLLRYLFGVLHNIEQHSSSNQMTAFNLAVCVAPSILWPPASSSPELENEFTKKVSLLI
QFLIENCLRIFGEEITSLFREVSVRCDTRENASDISCFQLNDSSYDSLENELNEDVDAPC
SDLVKKLGQGSRSMDSVLTLSDYDLDQPEVEGLLTLSDFDLAHSKDEDVQMKRPLESKPV
NILVYTKIPLRDHARAPSAMCTPSYLSTAAANAAKSLRRHRRCSEPSIDYLDSKLSYLRE
FYQKKLRKSSCDAILSQKDEDYLKQNQPLQEEGKTCFKQSLVTGTDVSKKNATTQNTKKK
SLSGSEGNHVKLFPKSKPVAISVASYSPMSSQDHSKNQPFDVNTSGYSPPHTADALKGPR
THRRCSEPNIEDQNRKLTYLRGIYSKKQHKTSCEAGLLHGEEDYLKRHKSLQMEGQKLIN
QSLVMGIEVGKSSATNQNTEKVLPPRLNLCPRTSYSSLSSPGTSPSGSSVSSQDSAFSQI
SEHSVFTPTETSSPIDCTFQAQRKREDLSPDFSNASHVSGMPGPSSGQACSRPAYTKKDT
MEWHSQMHSVTLHPSTWLRNGVASLKNWSLKKKAKAARPEEEKIASPKGPLEPPPHASGV
PEANSLQEEQKDLPLRAAEGLSPVQSAQRCSSSPFQDSERHCSSPFSLVESRLKLCMKSH
EEIEPGSQSSSGSLPWERASASSWTLEDATSPDSGPTVVCDIEDRYLTKDI

Sequence length

1191

Interactions

View interactions

	Reactome
			Rho GTPase cycle

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Coronary artery disease	Coronary artery disease	N/A	N/A	GWAS

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Neoplasms	Associate	33949771
Rectal Neoplasms	Associate	33949771

ARHGAP20 (Rho GTPase activating protein 20)