ZNF319 (zinc finger protein 319)

Gene

• Entrez ID: 57567
• Gene name: Zinc finger protein 319
• Gene symbol: ZNF319
• Synonyms (NCBI Gene): ZFP319
• Chromosome: 16
• Chromosome location: 16q21

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT651180	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT651179	hsa-miR-23c	HITS-CLIP	23824327
MIRT651178	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT651177	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT651176	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT651175	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT651174	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT651173	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT651172	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT651171	hsa-miR-6083	HITS-CLIP	23824327
MIRT651180	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT651179	hsa-miR-23c	HITS-CLIP	23824327
MIRT651178	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT651177	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT651176	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT651175	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT651174	hsa-miR-410-3p	HITS-CLIP	23824327
MIRT651173	hsa-miR-153-5p	HITS-CLIP	23824327
MIRT651172	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT651171	hsa-miR-6083	HITS-CLIP	23824327
MIRT1521847	hsa-miR-23a	CLIP-seq
MIRT1521848	hsa-miR-23b	CLIP-seq
MIRT1521849	hsa-miR-3127-5p	CLIP-seq
MIRT1521850	hsa-miR-3156-5p	CLIP-seq
MIRT1521851	hsa-miR-3160-5p	CLIP-seq
MIRT1521852	hsa-miR-377	CLIP-seq
MIRT1521853	hsa-miR-3942-3p	CLIP-seq
MIRT1521854	hsa-miR-410	CLIP-seq
MIRT1521855	hsa-miR-4433	CLIP-seq
MIRT1521856	hsa-miR-4755-3p	CLIP-seq
MIRT1521857	hsa-miR-495	CLIP-seq
MIRT1521858	hsa-miR-659	CLIP-seq
MIRT1521859	hsa-miR-665	CLIP-seq
MIRT1521860	hsa-miR-9	CLIP-seq
MIRT1555803	hsa-miR-3663-5p	CLIP-seq
MIRT1555804	hsa-miR-3925-3p	CLIP-seq
MIRT1555805	hsa-miR-4514	CLIP-seq
MIRT1555806	hsa-miR-4645-5p	CLIP-seq
MIRT1555807	hsa-miR-4673	CLIP-seq
MIRT1555808	hsa-miR-4692	CLIP-seq
MIRT1555809	hsa-miR-766	CLIP-seq
MIRT2157586	hsa-miR-1226	CLIP-seq
MIRT2157587	hsa-miR-3120-5p	CLIP-seq
MIRT2157588	hsa-miR-346	CLIP-seq
MIRT2157589	hsa-miR-4277	CLIP-seq
MIRT2157590	hsa-miR-4288	CLIP-seq
MIRT2157591	hsa-miR-4530	CLIP-seq
MIRT2157592	hsa-miR-4663	CLIP-seq
MIRT2157593	hsa-miR-615-5p	CLIP-seq
MIRT2157594	hsa-miR-632	CLIP-seq
MIRT2157595	hsa-miR-634	CLIP-seq
MIRT2377110	hsa-miR-1228	CLIP-seq
MIRT2377111	hsa-miR-1283	CLIP-seq
MIRT1521851	hsa-miR-3160-5p	CLIP-seq
MIRT2377112	hsa-miR-3176	CLIP-seq
MIRT2377113	hsa-miR-3914	CLIP-seq
MIRT2377114	hsa-miR-3922-3p	CLIP-seq
MIRT1521853	hsa-miR-3942-3p	CLIP-seq
MIRT2377115	hsa-miR-4323	CLIP-seq
MIRT2157591	hsa-miR-4530	CLIP-seq
MIRT2377116	hsa-miR-4793-3p	CLIP-seq
MIRT1521857	hsa-miR-495	CLIP-seq
MIRT2377117	hsa-miR-520d-5p	CLIP-seq
MIRT2377118	hsa-miR-524-5p	CLIP-seq
MIRT2377119	hsa-miR-548p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9P2F9
• Protein name: Zinc finger protein 319
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	202 → 224	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	230 → 252	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	258 → 280	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	315 → 337	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	343 → 365	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	371 → 393	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	428 → 450	Zinc finger, C2H2 type	Domain
  PF13465	zf-H2C2_2	500 → 525		Domain

• Sequence:

  MSESWQQPPQTQPQQPQPPQPQHHAEPPPALAEHTLPPGTAENPLGCAVYGILLQPDPGL
  QPPQHAPLQAAGEPGPKCGVCGHDLAHLSSPHEHQCLAGHDRSFQCTQCLKIFHQATDLL
  EHQCVQAEQKPFVCGVCKMGFSLLTSLAQHHSSHSGLVKCSICEKTYKPAEAAEPATTAA
  PSLPAAPAPSTVTPAEQADKPYSCPICQKPFKHLSELSRHERIHTGEKPYKCTLCDKSFS
  QSSHLVHHKRTHSSERPYKCAVCEKTFKHRSHLVRHMYAHSGEHHLFRCNVCELHFKESS
  ELLQHPCTPSGERPFRCGECQKAFKRPSDLRQHERTHSAERPFKCDLCPMGFKQQYALMR
  HRRTHKTEEPFKCGLCEKGFGQPSHLLYHQHVHTLETLFKCPVCQKGFDQSAELLRHKCL
  PGAAERPFKCPVCNKAYKRASALQKHQLAHCAAAEKPLRCTLCERRFFSSSEFVQHRCDP
  AREKPLKCPDCEKRFKYASDLQRHRRVHTGEKPYKCPNCDKAFKQREHLNKHQGVHAREQ
  QFKCVWCGERFLDVALLQEHSAQHSAAAAAAEGAYQVAACLP

• Sequence length: 582

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CHRONIC OBSTRUCTIVE PULMONARY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations