KLHL8 (kelch like family member 8)

Gene

• Entrez ID: 57563
• Gene name: Kelch like family member 8
• Gene symbol: KLHL8
• Synonyms (NCBI Gene): -
• Chromosome: 4
• Chromosome location: 4q22.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024647	hsa-miR-215-5p	Microarray	19074876
MIRT026842	hsa-miR-192-5p	Microarray	19074876
MIRT046891	hsa-miR-221-3p	CLASH	23622248
MIRT040093	hsa-miR-615-3p	CLASH	23622248
MIRT667702	hsa-miR-3121-3p	HITS-CLIP	23824327
MIRT667701	hsa-miR-6758-5p	HITS-CLIP	23824327
MIRT667700	hsa-miR-6856-5p	HITS-CLIP	23824327
MIRT667699	hsa-miR-3976	HITS-CLIP	23824327
MIRT667698	hsa-miR-498	HITS-CLIP	23824327
MIRT046891	hsa-miR-221-3p	PAR-CLIP	26701625
MIRT046891	hsa-miR-221-3p	PAR-CLIP	26701625
MIRT667702	hsa-miR-3121-3p	HITS-CLIP	23824327
MIRT667701	hsa-miR-6758-5p	HITS-CLIP	23824327
MIRT667700	hsa-miR-6856-5p	HITS-CLIP	23824327
MIRT667699	hsa-miR-3976	HITS-CLIP	23824327
MIRT667698	hsa-miR-498	HITS-CLIP	23824327
MIRT1098851	hsa-miR-1200	CLIP-seq
MIRT1098852	hsa-miR-1226	CLIP-seq
MIRT1098853	hsa-miR-1266	CLIP-seq
MIRT1098854	hsa-miR-1343	CLIP-seq
MIRT1098855	hsa-miR-141	CLIP-seq
MIRT1098856	hsa-miR-196a	CLIP-seq
MIRT1098857	hsa-miR-196b	CLIP-seq
MIRT1098858	hsa-miR-1976	CLIP-seq
MIRT1098859	hsa-miR-200a	CLIP-seq
MIRT1098860	hsa-miR-216a	CLIP-seq
MIRT1098861	hsa-miR-216b	CLIP-seq
MIRT1098862	hsa-miR-221	CLIP-seq
MIRT1098863	hsa-miR-222	CLIP-seq
MIRT1098864	hsa-miR-302a	CLIP-seq
MIRT1098865	hsa-miR-302b	CLIP-seq
MIRT1098866	hsa-miR-302c	CLIP-seq
MIRT1098867	hsa-miR-302d	CLIP-seq
MIRT1098868	hsa-miR-3133	CLIP-seq
MIRT1098869	hsa-miR-3150a-5p	CLIP-seq
MIRT1098870	hsa-miR-3150b-5p	CLIP-seq
MIRT1098871	hsa-miR-3183	CLIP-seq
MIRT1098872	hsa-miR-323b-5p	CLIP-seq
MIRT1098873	hsa-miR-338-3p	CLIP-seq
MIRT1098874	hsa-miR-3613-5p	CLIP-seq
MIRT1098875	hsa-miR-3664-3p	CLIP-seq
MIRT1098876	hsa-miR-372	CLIP-seq
MIRT1098877	hsa-miR-373	CLIP-seq
MIRT1098878	hsa-miR-3908	CLIP-seq
MIRT1098879	hsa-miR-3927	CLIP-seq
MIRT1098880	hsa-miR-3941	CLIP-seq
MIRT1098881	hsa-miR-3942-3p	CLIP-seq
MIRT1098882	hsa-miR-4261	CLIP-seq
MIRT1098883	hsa-miR-4279	CLIP-seq
MIRT1098884	hsa-miR-4317	CLIP-seq
MIRT1098885	hsa-miR-4324	CLIP-seq
MIRT1098886	hsa-miR-4496	CLIP-seq
MIRT1098887	hsa-miR-450b-5p	CLIP-seq
MIRT1098888	hsa-miR-4518	CLIP-seq
MIRT1098889	hsa-miR-4530	CLIP-seq
MIRT1098890	hsa-miR-4638-5p	CLIP-seq
MIRT1098891	hsa-miR-4641	CLIP-seq
MIRT1098892	hsa-miR-4650-3p	CLIP-seq
MIRT1098893	hsa-miR-466	CLIP-seq
MIRT1098894	hsa-miR-4672	CLIP-seq
MIRT1098895	hsa-miR-4722-3p	CLIP-seq
MIRT1098896	hsa-miR-4723-3p	CLIP-seq
MIRT1098897	hsa-miR-4731-3p	CLIP-seq
MIRT1098898	hsa-miR-4733-3p	CLIP-seq
MIRT1098899	hsa-miR-4787-3p	CLIP-seq
MIRT1098900	hsa-miR-4801	CLIP-seq
MIRT1098901	hsa-miR-495	CLIP-seq
MIRT1098902	hsa-miR-5095	CLIP-seq
MIRT1098903	hsa-miR-518a-5p	CLIP-seq
MIRT1098904	hsa-miR-519a	CLIP-seq
MIRT1098905	hsa-miR-527	CLIP-seq
MIRT1098906	hsa-miR-544b	CLIP-seq
MIRT1098907	hsa-miR-552	CLIP-seq
MIRT1098908	hsa-miR-584	CLIP-seq
MIRT1098909	hsa-miR-802	CLIP-seq
MIRT1098910	hsa-miR-873	CLIP-seq
MIRT2026844	hsa-miR-1193	CLIP-seq
MIRT1098851	hsa-miR-1200	CLIP-seq
MIRT2026845	hsa-miR-1224-3p	CLIP-seq
MIRT1098852	hsa-miR-1226	CLIP-seq
MIRT2026846	hsa-miR-125a-3p	CLIP-seq
MIRT1098853	hsa-miR-1266	CLIP-seq
MIRT2026847	hsa-miR-129-5p	CLIP-seq
MIRT1098854	hsa-miR-1343	CLIP-seq
MIRT1098856	hsa-miR-196a	CLIP-seq
MIRT1098857	hsa-miR-196b	CLIP-seq
MIRT2026848	hsa-miR-197	CLIP-seq
MIRT1098858	hsa-miR-1976	CLIP-seq
MIRT2026849	hsa-miR-2113	CLIP-seq
MIRT1098861	hsa-miR-216b	CLIP-seq
MIRT2026850	hsa-miR-29a	CLIP-seq
MIRT2026851	hsa-miR-29b	CLIP-seq
MIRT2026852	hsa-miR-29c	CLIP-seq
MIRT2026853	hsa-miR-3065-3p	CLIP-seq
MIRT2026854	hsa-miR-3119	CLIP-seq
MIRT2026855	hsa-miR-3127-5p	CLIP-seq
MIRT2026856	hsa-miR-323-5p	CLIP-seq
MIRT2026857	hsa-miR-331-5p	CLIP-seq
MIRT1098875	hsa-miR-3664-3p	CLIP-seq
MIRT1098879	hsa-miR-3927	CLIP-seq
MIRT2026858	hsa-miR-3934	CLIP-seq
MIRT1098883	hsa-miR-4279	CLIP-seq
MIRT1098885	hsa-miR-4324	CLIP-seq
MIRT2026859	hsa-miR-4426	CLIP-seq
MIRT2026860	hsa-miR-4474-3p	CLIP-seq
MIRT2026861	hsa-miR-4503	CLIP-seq
MIRT1098888	hsa-miR-4518	CLIP-seq
MIRT2026862	hsa-miR-4647	CLIP-seq
MIRT2026863	hsa-miR-4662b	CLIP-seq
MIRT2026864	hsa-miR-4678	CLIP-seq
MIRT1098895	hsa-miR-4722-3p	CLIP-seq
MIRT1098898	hsa-miR-4733-3p	CLIP-seq
MIRT2026865	hsa-miR-4735-5p	CLIP-seq
MIRT2026866	hsa-miR-4760-3p	CLIP-seq
MIRT2026867	hsa-miR-4775	CLIP-seq
MIRT1098899	hsa-miR-4787-3p	CLIP-seq
MIRT2026868	hsa-miR-4794	CLIP-seq
MIRT1098902	hsa-miR-5095	CLIP-seq
MIRT1098906	hsa-miR-544b	CLIP-seq
MIRT1098907	hsa-miR-552	CLIP-seq
MIRT2026869	hsa-miR-590-3p	CLIP-seq
MIRT2026870	hsa-miR-758	CLIP-seq
MIRT2026871	hsa-miR-764	CLIP-seq
MIRT2026872	hsa-miR-892b	CLIP-seq
MIRT1098851	hsa-miR-1200	CLIP-seq
MIRT1098852	hsa-miR-1226	CLIP-seq
MIRT2258083	hsa-miR-1271	CLIP-seq
MIRT2258084	hsa-miR-1279	CLIP-seq
MIRT1098854	hsa-miR-1343	CLIP-seq
MIRT2258085	hsa-miR-136	CLIP-seq
MIRT1098855	hsa-miR-141	CLIP-seq
MIRT2258086	hsa-miR-182	CLIP-seq
MIRT1098856	hsa-miR-196a	CLIP-seq
MIRT1098857	hsa-miR-196b	CLIP-seq
MIRT2026848	hsa-miR-197	CLIP-seq
MIRT1098858	hsa-miR-1976	CLIP-seq
MIRT1098859	hsa-miR-200a	CLIP-seq
MIRT2258087	hsa-miR-2054	CLIP-seq
MIRT2258088	hsa-miR-3117-5p	CLIP-seq
MIRT2026855	hsa-miR-3127-5p	CLIP-seq
MIRT2258089	hsa-miR-3137	CLIP-seq
MIRT2258090	hsa-miR-3145-5p	CLIP-seq
MIRT1098869	hsa-miR-3150a-5p	CLIP-seq
MIRT1098870	hsa-miR-3150b-5p	CLIP-seq
MIRT2258091	hsa-miR-3155	CLIP-seq
MIRT2258092	hsa-miR-3155b	CLIP-seq
MIRT2258093	hsa-miR-3162-3p	CLIP-seq
MIRT2026857	hsa-miR-331-5p	CLIP-seq
MIRT2258094	hsa-miR-338-5p	CLIP-seq
MIRT1098874	hsa-miR-3613-5p	CLIP-seq
MIRT2258095	hsa-miR-3663-5p	CLIP-seq
MIRT2258096	hsa-miR-3686	CLIP-seq
MIRT2258097	hsa-miR-382	CLIP-seq
MIRT1098879	hsa-miR-3927	CLIP-seq
MIRT2258098	hsa-miR-411	CLIP-seq
MIRT1098883	hsa-miR-4279	CLIP-seq
MIRT1098884	hsa-miR-4317	CLIP-seq
MIRT1098885	hsa-miR-4324	CLIP-seq
MIRT2026861	hsa-miR-4503	CLIP-seq
MIRT2258099	hsa-miR-4511	CLIP-seq
MIRT1098890	hsa-miR-4638-5p	CLIP-seq
MIRT2258100	hsa-miR-4676-5p	CLIP-seq
MIRT2026864	hsa-miR-4678	CLIP-seq
MIRT2258101	hsa-miR-4709-5p	CLIP-seq
MIRT2258102	hsa-miR-4714-3p	CLIP-seq
MIRT2258103	hsa-miR-4716-5p	CLIP-seq
MIRT1098895	hsa-miR-4722-3p	CLIP-seq
MIRT1098898	hsa-miR-4733-3p	CLIP-seq
MIRT2026865	hsa-miR-4735-5p	CLIP-seq
MIRT2026867	hsa-miR-4775	CLIP-seq
MIRT2258104	hsa-miR-4778-3p	CLIP-seq
MIRT2258105	hsa-miR-4778-5p	CLIP-seq
MIRT2258106	hsa-miR-4781-3p	CLIP-seq
MIRT1098899	hsa-miR-4787-3p	CLIP-seq
MIRT2026868	hsa-miR-4794	CLIP-seq
MIRT2258107	hsa-miR-484	CLIP-seq
MIRT1098901	hsa-miR-495	CLIP-seq
MIRT2258108	hsa-miR-508-5p	CLIP-seq
MIRT1098902	hsa-miR-5095	CLIP-seq
MIRT2258109	hsa-miR-5096	CLIP-seq
MIRT2258110	hsa-miR-513a-3p	CLIP-seq
MIRT2258111	hsa-miR-515-5p	CLIP-seq
MIRT1098906	hsa-miR-544b	CLIP-seq
MIRT2258112	hsa-miR-548b-3p	CLIP-seq
MIRT1098907	hsa-miR-552	CLIP-seq
MIRT2258113	hsa-miR-575	CLIP-seq
MIRT2026869	hsa-miR-590-3p	CLIP-seq
MIRT1098909	hsa-miR-802	CLIP-seq
MIRT2258114	hsa-miR-885-5p	CLIP-seq
MIRT2258115	hsa-miR-96	CLIP-seq
MIRT1098852	hsa-miR-1226	CLIP-seq
MIRT2026855	hsa-miR-3127-5p	CLIP-seq
MIRT2026857	hsa-miR-331-5p	CLIP-seq
MIRT2026861	hsa-miR-4503	CLIP-seq
MIRT2026864	hsa-miR-4678	CLIP-seq
MIRT1098898	hsa-miR-4733-3p	CLIP-seq
MIRT1098851	hsa-miR-1200	CLIP-seq
MIRT1098854	hsa-miR-1343	CLIP-seq
MIRT1098858	hsa-miR-1976	CLIP-seq
MIRT2258098	hsa-miR-411	CLIP-seq
MIRT1098883	hsa-miR-4279	CLIP-seq
MIRT1098885	hsa-miR-4324	CLIP-seq
MIRT1098895	hsa-miR-4722-3p	CLIP-seq
MIRT2026865	hsa-miR-4735-5p	CLIP-seq
MIRT2026867	hsa-miR-4775	CLIP-seq
MIRT1098899	hsa-miR-4787-3p	CLIP-seq
MIRT2026868	hsa-miR-4794	CLIP-seq
MIRT1098906	hsa-miR-544b	CLIP-seq
MIRT2026869	hsa-miR-590-3p	CLIP-seq
MIRT1098851	hsa-miR-1200	CLIP-seq
MIRT1098854	hsa-miR-1343	CLIP-seq
MIRT1098858	hsa-miR-1976	CLIP-seq
MIRT1098883	hsa-miR-4279	CLIP-seq
MIRT1098885	hsa-miR-4324	CLIP-seq
MIRT1098895	hsa-miR-4722-3p	CLIP-seq
MIRT1098906	hsa-miR-544b	CLIP-seq
MIRT1098851	hsa-miR-1200	CLIP-seq
MIRT1098852	hsa-miR-1226	CLIP-seq
MIRT2559048	hsa-miR-1243	CLIP-seq
MIRT2559049	hsa-miR-1290	CLIP-seq
MIRT1098854	hsa-miR-1343	CLIP-seq
MIRT1098855	hsa-miR-141	CLIP-seq
MIRT1098856	hsa-miR-196a	CLIP-seq
MIRT1098857	hsa-miR-196b	CLIP-seq
MIRT1098858	hsa-miR-1976	CLIP-seq
MIRT1098859	hsa-miR-200a	CLIP-seq
MIRT2559050	hsa-miR-21	CLIP-seq
MIRT1098862	hsa-miR-221	CLIP-seq
MIRT1098863	hsa-miR-222	CLIP-seq
MIRT1098864	hsa-miR-302a	CLIP-seq
MIRT1098865	hsa-miR-302b	CLIP-seq
MIRT1098866	hsa-miR-302c	CLIP-seq
MIRT1098867	hsa-miR-302d	CLIP-seq
MIRT2258088	hsa-miR-3117-5p	CLIP-seq
MIRT2026855	hsa-miR-3127-5p	CLIP-seq
MIRT1098868	hsa-miR-3133	CLIP-seq
MIRT2559051	hsa-miR-3167	CLIP-seq
MIRT2026857	hsa-miR-331-5p	CLIP-seq
MIRT1098873	hsa-miR-338-3p	CLIP-seq
MIRT2559052	hsa-miR-3654	CLIP-seq
MIRT1098876	hsa-miR-372	CLIP-seq
MIRT1098877	hsa-miR-373	CLIP-seq
MIRT1098878	hsa-miR-3908	CLIP-seq
MIRT1098879	hsa-miR-3927	CLIP-seq
MIRT1098880	hsa-miR-3941	CLIP-seq
MIRT1098881	hsa-miR-3942-3p	CLIP-seq
MIRT2258098	hsa-miR-411	CLIP-seq
MIRT1098883	hsa-miR-4279	CLIP-seq
MIRT1098885	hsa-miR-4324	CLIP-seq
MIRT2026861	hsa-miR-4503	CLIP-seq
MIRT1098889	hsa-miR-4530	CLIP-seq
MIRT1098891	hsa-miR-4641	CLIP-seq
MIRT1098892	hsa-miR-4650-3p	CLIP-seq
MIRT1098893	hsa-miR-466	CLIP-seq
MIRT1098894	hsa-miR-4672	CLIP-seq
MIRT2258100	hsa-miR-4676-5p	CLIP-seq
MIRT2026864	hsa-miR-4678	CLIP-seq
MIRT1098895	hsa-miR-4722-3p	CLIP-seq
MIRT1098897	hsa-miR-4731-3p	CLIP-seq
MIRT1098898	hsa-miR-4733-3p	CLIP-seq
MIRT2026865	hsa-miR-4735-5p	CLIP-seq
MIRT2026867	hsa-miR-4775	CLIP-seq
MIRT2258104	hsa-miR-4778-3p	CLIP-seq
MIRT1098899	hsa-miR-4787-3p	CLIP-seq
MIRT2026868	hsa-miR-4794	CLIP-seq
MIRT1098900	hsa-miR-4801	CLIP-seq
MIRT2258111	hsa-miR-515-5p	CLIP-seq
MIRT1098904	hsa-miR-519a	CLIP-seq
MIRT1098906	hsa-miR-544b	CLIP-seq
MIRT2258113	hsa-miR-575	CLIP-seq
MIRT2026869	hsa-miR-590-3p	CLIP-seq
MIRT2559053	hsa-miR-590-5p	CLIP-seq
MIRT2559054	hsa-miR-876-5p	CLIP-seq
MIRT1098851	hsa-miR-1200	CLIP-seq
MIRT1098852	hsa-miR-1226	CLIP-seq
MIRT1098854	hsa-miR-1343	CLIP-seq
MIRT2258085	hsa-miR-136	CLIP-seq
MIRT1098855	hsa-miR-141	CLIP-seq
MIRT1098856	hsa-miR-196a	CLIP-seq
MIRT1098857	hsa-miR-196b	CLIP-seq
MIRT1098858	hsa-miR-1976	CLIP-seq
MIRT1098859	hsa-miR-200a	CLIP-seq
MIRT2258088	hsa-miR-3117-5p	CLIP-seq
MIRT2026855	hsa-miR-3127-5p	CLIP-seq
MIRT1098868	hsa-miR-3133	CLIP-seq
MIRT2258090	hsa-miR-3145-5p	CLIP-seq
MIRT2258093	hsa-miR-3162-3p	CLIP-seq
MIRT2683635	hsa-miR-3163	CLIP-seq
MIRT2026857	hsa-miR-331-5p	CLIP-seq
MIRT1098873	hsa-miR-338-3p	CLIP-seq
MIRT1098878	hsa-miR-3908	CLIP-seq
MIRT1098879	hsa-miR-3927	CLIP-seq
MIRT1098880	hsa-miR-3941	CLIP-seq
MIRT1098881	hsa-miR-3942-3p	CLIP-seq
MIRT2258098	hsa-miR-411	CLIP-seq
MIRT1098883	hsa-miR-4279	CLIP-seq
MIRT1098885	hsa-miR-4324	CLIP-seq
MIRT2026861	hsa-miR-4503	CLIP-seq
MIRT1098887	hsa-miR-450b-5p	CLIP-seq
MIRT1098889	hsa-miR-4530	CLIP-seq
MIRT1098891	hsa-miR-4641	CLIP-seq
MIRT1098892	hsa-miR-4650-3p	CLIP-seq
MIRT1098893	hsa-miR-466	CLIP-seq
MIRT1098894	hsa-miR-4672	CLIP-seq
MIRT2258100	hsa-miR-4676-5p	CLIP-seq
MIRT2026864	hsa-miR-4678	CLIP-seq
MIRT1098895	hsa-miR-4722-3p	CLIP-seq
MIRT1098897	hsa-miR-4731-3p	CLIP-seq
MIRT1098898	hsa-miR-4733-3p	CLIP-seq
MIRT2026865	hsa-miR-4735-5p	CLIP-seq
MIRT2026867	hsa-miR-4775	CLIP-seq
MIRT2258104	hsa-miR-4778-3p	CLIP-seq
MIRT1098899	hsa-miR-4787-3p	CLIP-seq
MIRT2683636	hsa-miR-4793-3p	CLIP-seq
MIRT2026868	hsa-miR-4794	CLIP-seq
MIRT1098900	hsa-miR-4801	CLIP-seq
MIRT2258108	hsa-miR-508-5p	CLIP-seq
MIRT2258111	hsa-miR-515-5p	CLIP-seq
MIRT1098903	hsa-miR-518a-5p	CLIP-seq
MIRT1098905	hsa-miR-527	CLIP-seq
MIRT1098906	hsa-miR-544b	CLIP-seq
MIRT2258113	hsa-miR-575	CLIP-seq
MIRT2026869	hsa-miR-590-3p	CLIP-seq
MIRT2258114	hsa-miR-885-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21145461, 30190310, 32296183, 33961781, 34591642
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IDA	19158078
GO:0016567	Process	Protein ubiquitination	IDA	19158078
GO:0016567	Process	Protein ubiquitination	IEA
GO:0031463	Component	Cul3-RING ubiquitin ligase complex	IBA
GO:0031463	Component	Cul3-RING ubiquitin ligase complex	IDA	19158078
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IBA

Other IDs

• MIM: 611967
• HGNC: 18644
• e!Ensembl: ENSG00000145332

Protein

• UniProt ID: Q9P2G9
• Protein name: Kelch-like protein 8
• Protein function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00651	BTB	57 → 163	BTB/POZ domain	Domain
  PF07707	BACK	169 → 271	BTB And C-terminal Kelch	Domain
  PF01344	Kelch_1	316 → 353	Kelch motif	Repeat
  PF01344	Kelch_1	355 → 400	Kelch motif	Repeat
  PF01344	Kelch_1	402 → 447	Kelch motif	Repeat
  PF01344	Kelch_1	449 → 494	Kelch motif	Repeat
  PF01344	Kelch_1	496 → 541	Kelch motif	Repeat
  PF01344	Kelch_1	543 → 588	Kelch motif	Repeat

• Sequence:

  MASDSMSSKQARNHITKGKRQQQHQQIKNRSSISDGDGEDSFIFEANEAWKDFHGSLLRF
  YENGELCDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIED
  LVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHN
  RIDLMDMADQYACDHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYNAAIKWLLA
  NPQHHSKWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSRA
  VPDFEYSIRTTPRKHTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVG
  VISVEGKVYAVGGHDGNEHLGSMEMFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGG
  LDDNTCFNDVERYDIESDQWSTVAPMNTPRGGVGSVALVNHVYAVGGNDGMASLSSVERY
  DPHLDKWIEVKEMGQRRAGNGVSKLHGCLYVVGGFDDNSPLSSVERYDPRSNKWDYVAAL
  TTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDPVLNRWELVGSVSHCRAGAGVAVCS
  CLTSQIRDVGHGSNNVVDCM

• Sequence length: 620

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BULIMIA NERVOSA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CIRRHOSIS OF LIVER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GOUT	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPOGONADISM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INTRAHEPATIC BILE DUCT CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER NEOPLASM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROBLASTOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-ALCOHOLIC FATTY LIVER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POLYMORPHIC CATECHOLERGIC VENTRICULAR TACHYCARDIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Menopause Premature	Associate	33860118	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	27358489	★☆☆☆☆ Found in Text Mining only