Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	57562
Gene name Gene Name - the full gene name approved by the HGNC.	Centrosomal protein 126
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CEP126
Synonyms (NCBI Gene) Gene synonyms aliases	KIAA1377
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11q22.1

Show/Hide all(95)

miRTarBase ID	miRNA	Experiments	Reference
MIRT742247	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT742247	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT742247	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT742454	hsa-miR-26a-1-3p	HITS-CLIP	27418678
MIRT742455	hsa-miR-26a-2-3p	HITS-CLIP	27418678
MIRT742245	hsa-miR-3119	HITS-CLIP	27418678
MIRT740856	hsa-miR-6878-3p	HITS-CLIP	27418678
MIRT740814	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT740815	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT740816	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT740817	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT740818	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT740819	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT740820	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT740821	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT740822	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT740823	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT740824	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT740825	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT740826	hsa-miR-302e	HITS-CLIP	23313552
MIRT740827	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT740828	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT740829	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT740830	hsa-miR-520b	HITS-CLIP	23313552
MIRT740831	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT740832	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT740833	hsa-miR-520e	HITS-CLIP	23313552
MIRT740834	hsa-miR-4438	HITS-CLIP	23313552
MIRT740835	hsa-miR-512-3p	HITS-CLIP	23313552
MIRT740836	hsa-miR-6504-3p	HITS-CLIP	23313552
MIRT740837	hsa-miR-520g-3p	HITS-CLIP	23313552
MIRT740838	hsa-miR-520h	HITS-CLIP	23313552
MIRT740839	hsa-miR-186-3p	HITS-CLIP	23313552
MIRT740840	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT740841	hsa-miR-212-5p	HITS-CLIP	23313552
MIRT740842	hsa-miR-150-5p	HITS-CLIP	23313552
MIRT740843	hsa-miR-5186	HITS-CLIP	23313552
MIRT740844	hsa-miR-6778-3p	HITS-CLIP	23313552
MIRT740845	hsa-miR-4763-5p	HITS-CLIP	23313552
MIRT740846	hsa-miR-4312	HITS-CLIP	23313552
MIRT740847	hsa-miR-4663	HITS-CLIP	23313552
MIRT740848	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT740849	hsa-miR-8077	HITS-CLIP	23313552
MIRT740850	hsa-miR-4757-5p	HITS-CLIP	23313552
MIRT740851	hsa-miR-6744-3p	HITS-CLIP	23313552
MIRT740852	hsa-miR-5095	HITS-CLIP	23313552
MIRT740853	hsa-miR-7151-3p	HITS-CLIP	23313552
MIRT740854	hsa-miR-5001-3p	HITS-CLIP	23313552
MIRT740855	hsa-miR-6894-3p	HITS-CLIP	23313552
MIRT740856	hsa-miR-6878-3p	HITS-CLIP	23313552
MIRT740857	hsa-miR-1227-3p	HITS-CLIP	23313552
MIRT740858	hsa-miR-3149	HITS-CLIP	23313552
MIRT741756	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT741757	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT740840	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT741758	hsa-miR-325	HITS-CLIP	23824327
MIRT741759	hsa-miR-1976	HITS-CLIP	23824327
MIRT741760	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT741761	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT741762	hsa-miR-7975	HITS-CLIP	23824327
MIRT741756	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT741757	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT741758	hsa-miR-325	HITS-CLIP	23824327
MIRT741986	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT741759	hsa-miR-1976	HITS-CLIP	23824327
MIRT741762	hsa-miR-7975	HITS-CLIP	23824327
MIRT741987	hsa-miR-4279	HITS-CLIP	23824327
MIRT742244	hsa-miR-4778-5p	HITS-CLIP	23824327
MIRT742245	hsa-miR-3119	HITS-CLIP	23824327
MIRT742246	hsa-miR-4256	HITS-CLIP	23824327
MIRT740856	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT742247	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT742244	hsa-miR-4778-5p	HITS-CLIP	23824327
MIRT742245	hsa-miR-3119	HITS-CLIP	23824327
MIRT742246	hsa-miR-4256	HITS-CLIP	23824327
MIRT740856	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT742247	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT742244	hsa-miR-4778-5p	HITS-CLIP	23824327
MIRT742454	hsa-miR-26a-1-3p	HITS-CLIP	23824327
MIRT742455	hsa-miR-26a-2-3p	HITS-CLIP	23824327
MIRT742245	hsa-miR-3119	HITS-CLIP	23824327
MIRT742246	hsa-miR-4256	HITS-CLIP	23824327
MIRT740856	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT742454	hsa-miR-26a-1-3p	HITS-CLIP	23824327
MIRT742455	hsa-miR-26a-2-3p	HITS-CLIP	23824327
MIRT742245	hsa-miR-3119	HITS-CLIP	23824327
MIRT740856	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT742247	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT742244	hsa-miR-4778-5p	HITS-CLIP	23824327
MIRT742454	hsa-miR-26a-1-3p	HITS-CLIP	23824327
MIRT742455	hsa-miR-26a-2-3p	HITS-CLIP	23824327
MIRT742245	hsa-miR-3119	HITS-CLIP	23824327
MIRT742246	hsa-miR-4256	HITS-CLIP	23824327
MIRT740856	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT742247	hsa-miR-129-5p	HITS-CLIP	23824327

Show/Hide all(14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	15383276, 24867236
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IBA	21873635
GO:0005813	Component	Centrosome	IDA	24867236
GO:0007052	Process	Mitotic spindle organization	IMP	24867236
GO:0030496	Component	Midbody	IBA	21873635
GO:0030496	Component	Midbody	IDA	19799413
GO:0031122	Process	Cytoplasmic microtubule organization	IBA	21873635
GO:0031122	Process	Cytoplasmic microtubule organization	IMP	24867236
GO:0060271	Process	Cilium assembly	IBA	21873635
GO:0060271	Process	Cilium assembly	IMP	24867236
GO:0097546	Component	Ciliary base	IBA	21873635
GO:0097546	Component	Ciliary base	IDA	24867236
GO:1905515	Process	Non-motile cilium assembly	IEA

MIM	HGNC	e!Ensembl
614634	29264	ENSG00000110318

Protein

UniProt ID

Q9P2H0

Protein name

Centrosomal protein of 126 kDa

Protein function

Participates in cytokinesis (PubMed:19799413). Necessary for microtubules and mitotic spindle organization (PubMed:24867236). Involved in primary cilium formation (PubMed:24867236).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15352	K1377	105 → 1081	Susceptibility to monomelic amyotrophy	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain, lung, skeletal muscle, kidney, pancreas, testis and ovary. {ECO:0000269|PubMed:10718198}.

Sequence

MLAGRPGTRSAVGELGTESSDNLDRAPLGPRESGGHHRPGSYLDMKIHLEKNLEEERQIL
LQQQKICRNRARKYFVESNRRKKAFEEKRKEQEEKEHQIREQILQQRKQKFEEVTEKFQR
AHVPLSQRRKAVSRKPVPPLEEALKQIQESNLKSEVNLPFSRRPTINWRAIDSALPSALS
KNDHKHQKQLLSKINCEKEMNENMRATLATSKNVFQLKLEETQKLLEDQHLSNLQKFGDE
VNQITNSETLSSIDSLEATEHEEIYLTLNKEHSTSIQRNTISLKPANMQSTNLSCFDEDK
LAFSKTQHINNWLTNLDASNTQNVTAFSDILSKSNVLPSWEYFNSKEQNPSPLNGTVERA
TNTANNSVPFVSSPPMFVLDKKCEKTSETSTMRTTDSTSGAFKRERPLVTESPTFKFSKS
QSTSDSLTQEVATFPDQEKYSELNQENGTTSIPTSCVPVATPLVLPSNIQSARPSAKNSI
HIKEIDAVQCSDKLDELKDGKEEEIKYFNCNKEELPLFSDSFQDAYIPHNPDSKDEKQKL
AETSSLSNVTSNYDFVGQHKKMKYNIHERNGVRFLKSILKKESKYEHGYLKALIINQSFK
FGNQKAAAIRDSIELTKEKGAEIPKTIKKLRWFDETSNIENNAENSHSLKNKTGTTQQHS
QQFHIQSGAGSNIISVSTCAVNSADTKKSREDSISENVTTLGGSGADHMPLNCFIPSGYN
FAKHAWPASKKEESKIPVHDDSKTKQGKPQRGRAKIIRKPGSAKVQSGFICTNRKGAVIQ
PQSASKVNIFTQAQGKLIIPCPPPQSTSNIRSGKNIQVSQCQPVTPENPQNIITHNSFNS
KHVLPTEHSLNQWNQESSSPLSNACSDLVTVIPSLPSYCSSECQTFAKINHSNGTQAVAR
QDATLYCTQRSPVCEESYPSVTLRTAEEESVPLWKRGPNVLHQNKRATGSTVMRRKRIAE
TKRRNILEQKRQNPGSVGQKYSEQINNFGQSVLLSSSEPKQTTRGTSYIEEVSDSTSEFL
MAENLVKASVPEDEILTVLNSKQIQKSNLPLNKTQQFNICTLSAEEQKILESLNDLSERL
HYIQESICKNPSIKNTLQIIPLLEKREDRTSSCRDKR

Sequence length

1117

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Monomelic amyotrophy	Amyotrophy, monomelic, Monomelic amyotrophy		22264561	ClinVar

CEP126 (centrosomal protein 126)