MICAL3 (microtubule associated monooxygenase, calponin and LIM domain containing 3)

Gene

• Entrez ID: 57553
• Gene name: Microtubule associated monooxygenase, calponin and LIM domain containing 3
• Gene symbol: MICAL3
• Synonyms (NCBI Gene): MICAL-3
• Chromosome: 22
• Chromosome location: 22q11.21

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1148031	hsa-let-7a	CLIP-seq
MIRT1148032	hsa-let-7b	CLIP-seq
MIRT1148033	hsa-let-7c	CLIP-seq
MIRT1148034	hsa-let-7d	CLIP-seq
MIRT1148035	hsa-let-7e	CLIP-seq
MIRT1148036	hsa-let-7f	CLIP-seq
MIRT1148037	hsa-let-7g	CLIP-seq
MIRT1148038	hsa-let-7i	CLIP-seq
MIRT1148039	hsa-miR-1178	CLIP-seq
MIRT1148040	hsa-miR-1193	CLIP-seq
MIRT1148041	hsa-miR-1208	CLIP-seq
MIRT1148042	hsa-miR-122	CLIP-seq
MIRT1148043	hsa-miR-1245b-3p	CLIP-seq
MIRT1148044	hsa-miR-1273f	CLIP-seq
MIRT1148045	hsa-miR-128	CLIP-seq
MIRT1148046	hsa-miR-1302	CLIP-seq
MIRT1148047	hsa-miR-1343	CLIP-seq
MIRT1148048	hsa-miR-1913	CLIP-seq
MIRT1148049	hsa-miR-1976	CLIP-seq
MIRT1148050	hsa-miR-2392	CLIP-seq
MIRT1148051	hsa-miR-27a	CLIP-seq
MIRT1148052	hsa-miR-27b	CLIP-seq
MIRT1148053	hsa-miR-3121-5p	CLIP-seq
MIRT1148054	hsa-miR-3122	CLIP-seq
MIRT1148055	hsa-miR-3135b	CLIP-seq
MIRT1148056	hsa-miR-3152-3p	CLIP-seq
MIRT1148057	hsa-miR-3155	CLIP-seq
MIRT1148058	hsa-miR-3155b	CLIP-seq
MIRT1148059	hsa-miR-3194-3p	CLIP-seq
MIRT1148060	hsa-miR-3199	CLIP-seq
MIRT1148061	hsa-miR-324-3p	CLIP-seq
MIRT1148062	hsa-miR-329	CLIP-seq
MIRT1148063	hsa-miR-339-3p	CLIP-seq
MIRT1148064	hsa-miR-3545-5p	CLIP-seq
MIRT1148065	hsa-miR-362-3p	CLIP-seq
MIRT1148066	hsa-miR-3650	CLIP-seq
MIRT1148067	hsa-miR-3652	CLIP-seq
MIRT1148068	hsa-miR-3674	CLIP-seq
MIRT1148069	hsa-miR-3682-3p	CLIP-seq
MIRT1148070	hsa-miR-3913-5p	CLIP-seq
MIRT1148071	hsa-miR-3927	CLIP-seq
MIRT1148072	hsa-miR-4279	CLIP-seq
MIRT1148073	hsa-miR-4294	CLIP-seq
MIRT1148074	hsa-miR-4298	CLIP-seq
MIRT1148075	hsa-miR-4300	CLIP-seq
MIRT1148076	hsa-miR-4303	CLIP-seq
MIRT1148077	hsa-miR-431	CLIP-seq
MIRT1148078	hsa-miR-4330	CLIP-seq
MIRT1148079	hsa-miR-4420	CLIP-seq
MIRT1148080	hsa-miR-4430	CLIP-seq
MIRT1148081	hsa-miR-4438	CLIP-seq
MIRT1148082	hsa-miR-4451	CLIP-seq
MIRT1148083	hsa-miR-4457	CLIP-seq
MIRT1148084	hsa-miR-4458	CLIP-seq
MIRT1148085	hsa-miR-4500	CLIP-seq
MIRT1148086	hsa-miR-4511	CLIP-seq
MIRT1148087	hsa-miR-4519	CLIP-seq
MIRT1148088	hsa-miR-4662a-5p	CLIP-seq
MIRT1148089	hsa-miR-4676-5p	CLIP-seq
MIRT1148090	hsa-miR-4679	CLIP-seq
MIRT1148091	hsa-miR-4707-3p	CLIP-seq
MIRT1148092	hsa-miR-4719	CLIP-seq
MIRT1148093	hsa-miR-4722-3p	CLIP-seq
MIRT1148094	hsa-miR-4731-3p	CLIP-seq
MIRT1148095	hsa-miR-4732-5p	CLIP-seq
MIRT1148096	hsa-miR-4740-3p	CLIP-seq
MIRT1148097	hsa-miR-4795-5p	CLIP-seq
MIRT1148098	hsa-miR-4796-3p	CLIP-seq
MIRT1148099	hsa-miR-4801	CLIP-seq
MIRT1148100	hsa-miR-483-5p	CLIP-seq
MIRT1148101	hsa-miR-484	CLIP-seq
MIRT1148102	hsa-miR-5095	CLIP-seq
MIRT1148103	hsa-miR-513a-5p	CLIP-seq
MIRT1148104	hsa-miR-548ae	CLIP-seq
MIRT1148105	hsa-miR-548aj	CLIP-seq
MIRT1148106	hsa-miR-548al	CLIP-seq
MIRT1148107	hsa-miR-548am	CLIP-seq
MIRT1148108	hsa-miR-548x	CLIP-seq
MIRT1148109	hsa-miR-575	CLIP-seq
MIRT1148110	hsa-miR-892a	CLIP-seq
MIRT1148111	hsa-miR-920	CLIP-seq
MIRT1148112	hsa-miR-924	CLIP-seq
MIRT1148113	hsa-miR-95	CLIP-seq
MIRT1148114	hsa-miR-98	CLIP-seq
MIRT1148115	hsa-miR-1182	CLIP-seq
MIRT1148116	hsa-miR-1185	CLIP-seq
MIRT1148117	hsa-miR-1202	CLIP-seq
MIRT1148118	hsa-miR-1234	CLIP-seq
MIRT1148043	hsa-miR-1245b-3p	CLIP-seq
MIRT1148119	hsa-miR-127-5p	CLIP-seq
MIRT1148120	hsa-miR-1297	CLIP-seq
MIRT1148121	hsa-miR-1305	CLIP-seq
MIRT1148122	hsa-miR-138	CLIP-seq
MIRT1148123	hsa-miR-19a	CLIP-seq
MIRT1148124	hsa-miR-19b	CLIP-seq
MIRT1148125	hsa-miR-204	CLIP-seq
MIRT1148126	hsa-miR-211	CLIP-seq
MIRT1148127	hsa-miR-214	CLIP-seq
MIRT1148050	hsa-miR-2392	CLIP-seq
MIRT1148128	hsa-miR-26a	CLIP-seq
MIRT1148129	hsa-miR-26b	CLIP-seq
MIRT1148130	hsa-miR-28-5p	CLIP-seq
MIRT1148131	hsa-miR-3120-5p	CLIP-seq
MIRT1148132	hsa-miR-3139	CLIP-seq
MIRT1148133	hsa-miR-3148	CLIP-seq
MIRT1148134	hsa-miR-3151	CLIP-seq
MIRT1148135	hsa-miR-3187-3p	CLIP-seq
MIRT1148136	hsa-miR-323b-5p	CLIP-seq
MIRT1148137	hsa-miR-346	CLIP-seq
MIRT1148138	hsa-miR-3605-5p	CLIP-seq
MIRT1148139	hsa-miR-3619-5p	CLIP-seq
MIRT1148140	hsa-miR-3663-3p	CLIP-seq
MIRT1148141	hsa-miR-3679-5p	CLIP-seq
MIRT1148142	hsa-miR-3682-5p	CLIP-seq
MIRT1148143	hsa-miR-3938	CLIP-seq
MIRT1148144	hsa-miR-3972	CLIP-seq
MIRT1148145	hsa-miR-4265	CLIP-seq
MIRT1148146	hsa-miR-4282	CLIP-seq
MIRT1148147	hsa-miR-4288	CLIP-seq
MIRT1148148	hsa-miR-4296	CLIP-seq
MIRT1148077	hsa-miR-431	CLIP-seq
MIRT1148149	hsa-miR-4317	CLIP-seq
MIRT1148150	hsa-miR-4322	CLIP-seq
MIRT1148151	hsa-miR-4421	CLIP-seq
MIRT1148152	hsa-miR-4435	CLIP-seq
MIRT1148153	hsa-miR-4447	CLIP-seq
MIRT1148154	hsa-miR-4465	CLIP-seq
MIRT1148155	hsa-miR-4472	CLIP-seq
MIRT1148156	hsa-miR-4488	CLIP-seq
MIRT1148157	hsa-miR-4493	CLIP-seq
MIRT1148158	hsa-miR-4530	CLIP-seq
MIRT1148159	hsa-miR-4633-3p	CLIP-seq
MIRT1148160	hsa-miR-4640-5p	CLIP-seq
MIRT1148161	hsa-miR-4645-5p	CLIP-seq
MIRT1148162	hsa-miR-4663	CLIP-seq
MIRT1148163	hsa-miR-4670-3p	CLIP-seq
MIRT1148164	hsa-miR-4673	CLIP-seq
MIRT1148165	hsa-miR-4697-5p	CLIP-seq
MIRT1148166	hsa-miR-4698	CLIP-seq
MIRT1148167	hsa-miR-4701-5p	CLIP-seq
MIRT1148168	hsa-miR-4722-5p	CLIP-seq
MIRT1148169	hsa-miR-4726-5p	CLIP-seq
MIRT1148170	hsa-miR-4727-5p	CLIP-seq
MIRT1148171	hsa-miR-4755-3p	CLIP-seq
MIRT1148172	hsa-miR-4755-5p	CLIP-seq
MIRT1148173	hsa-miR-4769-3p	CLIP-seq
MIRT1148174	hsa-miR-488	CLIP-seq
MIRT1148175	hsa-miR-491-5p	CLIP-seq
MIRT1148176	hsa-miR-498	CLIP-seq
MIRT1148177	hsa-miR-544b	CLIP-seq
MIRT1148178	hsa-miR-548s	CLIP-seq
MIRT1148179	hsa-miR-579	CLIP-seq
MIRT1148180	hsa-miR-588	CLIP-seq
MIRT1148181	hsa-miR-623	CLIP-seq
MIRT1148182	hsa-miR-624	CLIP-seq
MIRT1148183	hsa-miR-632	CLIP-seq
MIRT1148184	hsa-miR-637	CLIP-seq
MIRT1148185	hsa-miR-708	CLIP-seq
MIRT1148186	hsa-miR-761	CLIP-seq
MIRT1148187	hsa-miR-888	CLIP-seq
MIRT1148113	hsa-miR-95	CLIP-seq
MIRT1148115	hsa-miR-1182	CLIP-seq
MIRT1148135	hsa-miR-3187-3p	CLIP-seq
MIRT1148152	hsa-miR-4435	CLIP-seq
MIRT1148161	hsa-miR-4645-5p	CLIP-seq
MIRT1148164	hsa-miR-4673	CLIP-seq
MIRT1148167	hsa-miR-4701-5p	CLIP-seq
MIRT1148178	hsa-miR-548s	CLIP-seq
MIRT1148180	hsa-miR-588	CLIP-seq
MIRT1148040	hsa-miR-1193	CLIP-seq
MIRT1148041	hsa-miR-1208	CLIP-seq
MIRT1148048	hsa-miR-1913	CLIP-seq
MIRT1148049	hsa-miR-1976	CLIP-seq
MIRT1148050	hsa-miR-2392	CLIP-seq
MIRT1148056	hsa-miR-3152-3p	CLIP-seq
MIRT1148061	hsa-miR-324-3p	CLIP-seq
MIRT1921680	hsa-miR-411	CLIP-seq
MIRT1148079	hsa-miR-4420	CLIP-seq
MIRT1148088	hsa-miR-4662a-5p	CLIP-seq
MIRT1148089	hsa-miR-4676-5p	CLIP-seq
MIRT1148091	hsa-miR-4707-3p	CLIP-seq
MIRT1148100	hsa-miR-483-5p	CLIP-seq
MIRT1148109	hsa-miR-575	CLIP-seq
MIRT1148110	hsa-miR-892a	CLIP-seq
MIRT1148040	hsa-miR-1193	CLIP-seq
MIRT1148041	hsa-miR-1208	CLIP-seq
MIRT1922232	hsa-miR-129-5p	CLIP-seq
MIRT1148048	hsa-miR-1913	CLIP-seq
MIRT1148049	hsa-miR-1976	CLIP-seq
MIRT1148050	hsa-miR-2392	CLIP-seq
MIRT1922233	hsa-miR-3149	CLIP-seq
MIRT1148056	hsa-miR-3152-3p	CLIP-seq
MIRT1148061	hsa-miR-324-3p	CLIP-seq
MIRT1921680	hsa-miR-411	CLIP-seq
MIRT1148079	hsa-miR-4420	CLIP-seq
MIRT1148088	hsa-miR-4662a-5p	CLIP-seq
MIRT1148089	hsa-miR-4676-5p	CLIP-seq
MIRT1148091	hsa-miR-4707-3p	CLIP-seq
MIRT1922234	hsa-miR-4775	CLIP-seq
MIRT1148100	hsa-miR-483-5p	CLIP-seq
MIRT1148109	hsa-miR-575	CLIP-seq
MIRT1922235	hsa-miR-590-3p	CLIP-seq
MIRT1148110	hsa-miR-892a	CLIP-seq
MIRT1148040	hsa-miR-1193	CLIP-seq
MIRT1148048	hsa-miR-1913	CLIP-seq
MIRT1148049	hsa-miR-1976	CLIP-seq
MIRT1148050	hsa-miR-2392	CLIP-seq
MIRT1148056	hsa-miR-3152-3p	CLIP-seq
MIRT1148061	hsa-miR-324-3p	CLIP-seq
MIRT1148088	hsa-miR-4662a-5p	CLIP-seq
MIRT1148089	hsa-miR-4676-5p	CLIP-seq
MIRT1148091	hsa-miR-4707-3p	CLIP-seq
MIRT1148109	hsa-miR-575	CLIP-seq
MIRT1148110	hsa-miR-892a	CLIP-seq
MIRT2042153	hsa-miR-1207-3p	CLIP-seq
MIRT2042154	hsa-miR-125a-3p	CLIP-seq
MIRT2042155	hsa-miR-1273g	CLIP-seq
MIRT1148045	hsa-miR-128	CLIP-seq
MIRT1148120	hsa-miR-1297	CLIP-seq
MIRT1148122	hsa-miR-138	CLIP-seq
MIRT2042156	hsa-miR-145	CLIP-seq
MIRT2042157	hsa-miR-1972	CLIP-seq
MIRT1148128	hsa-miR-26a	CLIP-seq
MIRT1148129	hsa-miR-26b	CLIP-seq
MIRT1148138	hsa-miR-3605-5p	CLIP-seq
MIRT2042158	hsa-miR-3665	CLIP-seq
MIRT1148142	hsa-miR-3682-5p	CLIP-seq
MIRT2042159	hsa-miR-383	CLIP-seq
MIRT2042160	hsa-miR-4269	CLIP-seq
MIRT2042161	hsa-miR-4277	CLIP-seq
MIRT2042162	hsa-miR-4302	CLIP-seq
MIRT1148152	hsa-miR-4435	CLIP-seq
MIRT1148154	hsa-miR-4465	CLIP-seq
MIRT2042163	hsa-miR-4474-3p	CLIP-seq
MIRT2042164	hsa-miR-4660	CLIP-seq
MIRT1148163	hsa-miR-4670-3p	CLIP-seq
MIRT2042165	hsa-miR-4685-5p	CLIP-seq
MIRT1148166	hsa-miR-4698	CLIP-seq
MIRT2042166	hsa-miR-4710	CLIP-seq
MIRT2042167	hsa-miR-4772-5p	CLIP-seq
MIRT2042168	hsa-miR-4779	CLIP-seq
MIRT2042169	hsa-miR-601	CLIP-seq
MIRT2042170	hsa-miR-765	CLIP-seq
MIRT1148056	hsa-miR-3152-3p	CLIP-seq
MIRT2271882	hsa-miR-4735-5p	CLIP-seq
MIRT1148110	hsa-miR-892a	CLIP-seq
MIRT2271883	hsa-miR-1226	CLIP-seq
MIRT1148120	hsa-miR-1297	CLIP-seq
MIRT1148121	hsa-miR-1305	CLIP-seq
MIRT1148128	hsa-miR-26a	CLIP-seq
MIRT1148129	hsa-miR-26b	CLIP-seq
MIRT2271884	hsa-miR-3183	CLIP-seq
MIRT1148078	hsa-miR-4330	CLIP-seq
MIRT1148154	hsa-miR-4465	CLIP-seq
MIRT2271885	hsa-miR-4650-5p	CLIP-seq
MIRT2271886	hsa-miR-4723-3p	CLIP-seq
MIRT1148171	hsa-miR-4755-3p	CLIP-seq
MIRT2271887	hsa-miR-642a	CLIP-seq
MIRT2271888	hsa-miR-646	CLIP-seq
MIRT1148042	hsa-miR-122	CLIP-seq
MIRT1148045	hsa-miR-128	CLIP-seq
MIRT2454120	hsa-miR-1289	CLIP-seq
MIRT1922232	hsa-miR-129-5p	CLIP-seq
MIRT1148047	hsa-miR-1343	CLIP-seq
MIRT2454121	hsa-miR-3064-3p	CLIP-seq
MIRT1148055	hsa-miR-3135b	CLIP-seq
MIRT1922233	hsa-miR-3149	CLIP-seq
MIRT1148057	hsa-miR-3155	CLIP-seq
MIRT1148058	hsa-miR-3155b	CLIP-seq
MIRT1148059	hsa-miR-3194-3p	CLIP-seq
MIRT2454122	hsa-miR-3198	CLIP-seq
MIRT1148067	hsa-miR-3652	CLIP-seq
MIRT1921680	hsa-miR-411	CLIP-seq
MIRT2454123	hsa-miR-4292	CLIP-seq
MIRT1148073	hsa-miR-4294	CLIP-seq
MIRT2454124	hsa-miR-4309	CLIP-seq
MIRT1148077	hsa-miR-431	CLIP-seq
MIRT1148080	hsa-miR-4430	CLIP-seq
MIRT1148081	hsa-miR-4438	CLIP-seq
MIRT2454125	hsa-miR-4534	CLIP-seq
MIRT2454126	hsa-miR-4715-3p	CLIP-seq
MIRT2454127	hsa-miR-4725-5p	CLIP-seq
MIRT2271882	hsa-miR-4735-5p	CLIP-seq
MIRT1922234	hsa-miR-4775	CLIP-seq
MIRT1148100	hsa-miR-483-5p	CLIP-seq
MIRT1148101	hsa-miR-484	CLIP-seq
MIRT2454128	hsa-miR-504	CLIP-seq
MIRT1148102	hsa-miR-5095	CLIP-seq
MIRT1922235	hsa-miR-590-3p	CLIP-seq
MIRT1148112	hsa-miR-924	CLIP-seq
MIRT2454129	hsa-miR-941	CLIP-seq
MIRT1922232	hsa-miR-129-5p	CLIP-seq
MIRT1922233	hsa-miR-3149	CLIP-seq
MIRT1921680	hsa-miR-411	CLIP-seq
MIRT2271882	hsa-miR-4735-5p	CLIP-seq
MIRT1922234	hsa-miR-4775	CLIP-seq
MIRT1148100	hsa-miR-483-5p	CLIP-seq
MIRT1922235	hsa-miR-590-3p	CLIP-seq
MIRT2454129	hsa-miR-941	CLIP-seq
MIRT2271883	hsa-miR-1226	CLIP-seq
MIRT1148049	hsa-miR-1976	CLIP-seq
MIRT2570741	hsa-miR-224	CLIP-seq
MIRT2570742	hsa-miR-2861	CLIP-seq
MIRT2570743	hsa-miR-3117-5p	CLIP-seq
MIRT2570744	hsa-miR-3120-3p	CLIP-seq
MIRT2570745	hsa-miR-3176	CLIP-seq
MIRT2570746	hsa-miR-3186-3p	CLIP-seq
MIRT2570747	hsa-miR-3667-3p	CLIP-seq
MIRT2570748	hsa-miR-3689a-3p	CLIP-seq
MIRT2570749	hsa-miR-3689c	CLIP-seq
MIRT2570750	hsa-miR-370	CLIP-seq
MIRT2570751	hsa-miR-378g	CLIP-seq
MIRT2570752	hsa-miR-3922-3p	CLIP-seq
MIRT2570753	hsa-miR-4283	CLIP-seq
MIRT2570754	hsa-miR-4286	CLIP-seq
MIRT2570755	hsa-miR-4437	CLIP-seq
MIRT2570756	hsa-miR-4489	CLIP-seq
MIRT2570757	hsa-miR-4674	CLIP-seq
MIRT1148167	hsa-miR-4701-5p	CLIP-seq
MIRT2570758	hsa-miR-4717-5p	CLIP-seq
MIRT2570759	hsa-miR-4728-5p	CLIP-seq
MIRT2570760	hsa-miR-4733-3p	CLIP-seq
MIRT2570761	hsa-miR-483-3p	CLIP-seq
MIRT2570762	hsa-miR-541	CLIP-seq
MIRT1148180	hsa-miR-588	CLIP-seq
MIRT2570763	hsa-miR-600	CLIP-seq
MIRT2570764	hsa-miR-654-5p	CLIP-seq
MIRT1148187	hsa-miR-888	CLIP-seq
MIRT2570765	hsa-miR-922	CLIP-seq
MIRT2570742	hsa-miR-2861	CLIP-seq
MIRT2570748	hsa-miR-3689a-3p	CLIP-seq
MIRT2570749	hsa-miR-3689c	CLIP-seq
MIRT2570759	hsa-miR-4728-5p	CLIP-seq
MIRT2570762	hsa-miR-541	CLIP-seq
MIRT2570764	hsa-miR-654-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003779	Function	Actin binding	IDA	24440334
GO:0003779	Function	Actin binding	IEA
GO:0003779	Function	Actin binding	ISS
GO:0004497	Function	Monooxygenase activity	IEA
GO:0005515	Function	Protein binding	IPI	27528609
GO:0005634	Component	Nucleus	IDA	24440334
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005819	Component	Spindle	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IDA
GO:0005938	Component	Cell cortex	IEA
GO:0006887	Process	Exocytosis	IEA
GO:0007010	Process	Cytoskeleton organization	IDA	24440334
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016709	Function	Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	ISS
GO:0030042	Process	Actin filament depolymerization	IDA	24440334
GO:0030042	Process	Actin filament depolymerization	IEA
GO:0030042	Process	Actin filament depolymerization	ISS
GO:0030496	Component	Midbody	IEA
GO:0042995	Component	Cell projection	IEA
GO:0045171	Component	Intercellular bridge	IDA
GO:0046872	Function	Metal ion binding	IEA
GO:0051301	Process	Cell division	IEA
GO:0060090	Function	Molecular adaptor activity	EXP	27528609
GO:0071949	Function	FAD binding	IEA
GO:0071949	Function	FAD binding	ISS
GO:0090543	Component	Flemming body	IDA
GO:0120501	Function	F-actin monooxygenase activity	IEA

Other IDs

• MIM: 608882
• HGNC: 24694
• e!Ensembl: ENSG00000243156

Protein

• UniProt ID: Q7RTP6
• Protein name: [F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3)
• Protein function: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of acti
• PDB: 2D88, 5SZG, 6ICI
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01494	FAD_binding_3	86 → 141	FAD binding domain	Family
  PF00307	CH	519 → 625	Calponin homology (CH) domain	Domain
  PF00412	LIM	764 → 822	LIM domain	Domain
  PF12130	DUF3585	1854 → 1988	Bivalent Mical/EHBP Rab binding domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:15694364}.
• Sequence:

  MEERKHETMNPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYW
  KAKALWAKLDKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA
  FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVN
  VEFQGLIQPPEDQENERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGK
  LAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFV
  MTAKKQSLLDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINH
  YGQPDVAMFDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMD
  SAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLR
  PSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNV
  TDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKE
  MASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQT
  ISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQN
  KVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAE
  GKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKE
  AKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPSIAKRLRGTPERIELENYRLSL
  RQAEALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESEMEEEGEEEEEEPRLPPSDLGG
  VPWKEAVRIHALLKGKSEEELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAG
  NQRLQQVMHAADPLEIQADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEP
  AEIEGEAAEDGDPGDTGAELDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKL
  PASPKHQERGPSQATSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPE
  PLLPKEKPKADAPSDLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPSPLPI
  CSQPQPSTEATVPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRR
  SDLVEEFWMKSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLL
  KPLSIPKRLGLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTL
  GSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPATWMRPPRE
  PAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWPRPEKPRHPP
  LAKENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQLSRM
  QQMELASGAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTLKHEATSEEVLSPPSDSG
  GPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEEAAAKPKSLW
  KSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLS
  SDDVLEKSSQKSRREPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQ
  VEERQRRLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARE
  LELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLR
  EREEDKDLEAAMLSKGFSLNWS

• Sequence length: 2002

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Hepatocellular carcinoma	Uncertain significance	rs200619290	RCV005929200

Associations from Text Mining
Disease Name	Relationship Type	References
COVID 19	Associate	35657140
Osteoarthritis	Associate	22385522