MICAL3 (microtubule associated monooxygenase, calponin and LIM domain containing 3)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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57553 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Microtubule associated monooxygenase, calponin and LIM domain containing 3 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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MICAL3 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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MICAL-3 |
Chromosome
Chromosome number
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22 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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22q11.21 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||
UniProt ID | Q7RTP6 | |||||||||||||||||||||||||
Protein name | [F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3) | |||||||||||||||||||||||||
Protein function | Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization. In the absence of acti | |||||||||||||||||||||||||
PDB | 2D88 , 5SZG , 6ICI | |||||||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:15694364}. | |||||||||||||||||||||||||
Sequence |
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Sequence length | 2002 | |||||||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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