Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	57537
Gene name	Sortilin related VPS10 domain containing receptor 2
Gene symbol	SORCS2
Synonyms (NCBI Gene)	-
Chromosome	4
Chromosome location	4p16.1
Summary	This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many e

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miRTarBase ID	miRNA	Experiments	Reference
MIRT046267	hsa-miR-23b-3p	CLASH	23622248
MIRT617529	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT617528	hsa-miR-3183	HITS-CLIP	23824327
MIRT617527	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT617526	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT617525	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617524	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT617523	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT643045	hsa-miR-567	HITS-CLIP	23824327
MIRT643044	hsa-miR-1206	HITS-CLIP	23824327
MIRT643043	hsa-miR-6853-3p	HITS-CLIP	23824327
MIRT617522	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT617525	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617524	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT617523	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT617522	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT617525	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617529	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT617528	hsa-miR-3183	HITS-CLIP	23824327
MIRT617527	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT617526	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT617525	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617524	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT617523	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT617522	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT486367	hsa-miR-4453	PAR-CLIP	20371350
MIRT486368	hsa-miR-4538	PAR-CLIP	20371350
MIRT486366	hsa-miR-5088-3p	PAR-CLIP	20371350
MIRT486365	hsa-miR-671-3p	PAR-CLIP	20371350
MIRT486364	hsa-miR-6070	PAR-CLIP	20371350
MIRT486363	hsa-miR-642b-5p	PAR-CLIP	20371350
MIRT486362	hsa-miR-623	PAR-CLIP	20371350
MIRT486361	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT486360	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT486359	hsa-miR-29b-2-5p	PAR-CLIP	20371350
MIRT486358	hsa-miR-3692-3p	PAR-CLIP	20371350
MIRT486357	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT486356	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT526299	hsa-miR-1306-5p	PAR-CLIP	20371350
MIRT526298	hsa-miR-4691-3p	PAR-CLIP	20371350
MIRT526297	hsa-miR-326	PAR-CLIP	20371350
MIRT526296	hsa-miR-330-5p	PAR-CLIP	20371350
MIRT526295	hsa-miR-3157-5p	PAR-CLIP	20371350
MIRT526299	hsa-miR-1306-5p	PAR-CLIP	22012620
MIRT526298	hsa-miR-4691-3p	PAR-CLIP	22012620
MIRT526297	hsa-miR-326	PAR-CLIP	22012620
MIRT526296	hsa-miR-330-5p	PAR-CLIP	22012620
MIRT526295	hsa-miR-3157-5p	PAR-CLIP	22012620
MIRT486367	hsa-miR-4453	PAR-CLIP	23592263
MIRT486368	hsa-miR-4538	PAR-CLIP	23592263
MIRT486366	hsa-miR-5088-3p	PAR-CLIP	23592263
MIRT486365	hsa-miR-671-3p	PAR-CLIP	23592263
MIRT486364	hsa-miR-6070	PAR-CLIP	23592263
MIRT486363	hsa-miR-642b-5p	PAR-CLIP	23592263
MIRT486362	hsa-miR-623	PAR-CLIP	23592263
MIRT486361	hsa-miR-204-5p	PAR-CLIP	23592263
MIRT486360	hsa-miR-211-5p	PAR-CLIP	23592263
MIRT486359	hsa-miR-29b-2-5p	PAR-CLIP	23592263
MIRT486358	hsa-miR-3692-3p	PAR-CLIP	23592263
MIRT486357	hsa-miR-4755-5p	PAR-CLIP	23592263
MIRT486356	hsa-miR-5006-3p	PAR-CLIP	23592263
MIRT452475	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT452474	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT452473	hsa-miR-4779	PAR-CLIP	23592263
MIRT452472	hsa-miR-1321	PAR-CLIP	23592263
MIRT452471	hsa-miR-4739	PAR-CLIP	23592263
MIRT452470	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT452469	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT452468	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT452467	hsa-miR-6752-3p	PAR-CLIP	23592263
MIRT452466	hsa-miR-4722-3p	PAR-CLIP	23592263
MIRT452465	hsa-miR-6727-3p	PAR-CLIP	23592263
MIRT452464	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452463	hsa-miR-4510	PAR-CLIP	23592263
MIRT452462	hsa-miR-6127	PAR-CLIP	23592263
MIRT452461	hsa-miR-6129	PAR-CLIP	23592263
MIRT452460	hsa-miR-6130	PAR-CLIP	23592263
MIRT452459	hsa-miR-6133	PAR-CLIP	23592263
MIRT452458	hsa-miR-765	PAR-CLIP	23592263
MIRT452457	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT452456	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT452455	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT452454	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT452453	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT452452	hsa-miR-5698	PAR-CLIP	23592263
MIRT452451	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT452449	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT452450	hsa-miR-548l	PAR-CLIP	23592263
MIRT452448	hsa-miR-3173-3p	PAR-CLIP	23592263
MIRT452447	hsa-miR-6891-5p	PAR-CLIP	23592263
MIRT452446	hsa-miR-141-5p	PAR-CLIP	23592263
MIRT452445	hsa-miR-205-3p	PAR-CLIP	23592263
MIRT452444	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT452443	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT449176	hsa-miR-106a-5p	PAR-CLIP	22100165
MIRT449175	hsa-miR-106b-5p	PAR-CLIP	22100165
MIRT449174	hsa-miR-17-5p	PAR-CLIP	22100165
MIRT449173	hsa-miR-20a-5p	PAR-CLIP	22100165
MIRT449172	hsa-miR-20b-5p	PAR-CLIP	22100165
MIRT449171	hsa-miR-519d-3p	PAR-CLIP	22100165
MIRT449170	hsa-miR-526b-3p	PAR-CLIP	22100165
MIRT449169	hsa-miR-93-5p	PAR-CLIP	22100165
MIRT449168	hsa-miR-302a-3p	PAR-CLIP	22100165
MIRT449167	hsa-miR-302b-3p	PAR-CLIP	22100165
MIRT449157	hsa-miR-302c-3p	PAR-CLIP	22100165
MIRT449166	hsa-miR-302d-3p	PAR-CLIP	22100165
MIRT449165	hsa-miR-302e	PAR-CLIP	22100165
MIRT449164	hsa-miR-372-3p	PAR-CLIP	22100165
MIRT449163	hsa-miR-373-3p	PAR-CLIP	22100165
MIRT449162	hsa-miR-520a-3p	PAR-CLIP	22100165
MIRT449161	hsa-miR-520b	PAR-CLIP	22100165
MIRT449160	hsa-miR-520c-3p	PAR-CLIP	22100165
MIRT449159	hsa-miR-520d-3p	PAR-CLIP	22100165
MIRT449158	hsa-miR-520e	PAR-CLIP	22100165
MIRT449157	hsa-miR-302c-3p	PAR-CLIP	22100165
MIRT449156	hsa-miR-520f-3p	PAR-CLIP	22100165
MIRT449155	hsa-miR-636	PAR-CLIP	22100165
MIRT449154	hsa-miR-1273e	PAR-CLIP	22100165
MIRT449153	hsa-miR-6818-5p	PAR-CLIP	22100165
MIRT737476	hsa-miR-4274	RNA-seq	31781574
MIRT617529	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT617528	hsa-miR-3183	HITS-CLIP	23824327
MIRT617527	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT617526	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT617525	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617524	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT617523	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT643045	hsa-miR-567	HITS-CLIP	23824327
MIRT643044	hsa-miR-1206	HITS-CLIP	23824327
MIRT643043	hsa-miR-6853-3p	HITS-CLIP	23824327
MIRT617522	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT617525	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617524	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT617523	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT617522	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT617525	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617529	hsa-miR-6800-3p	HITS-CLIP	23824327
MIRT617528	hsa-miR-3183	HITS-CLIP	23824327
MIRT617527	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT617526	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT617525	hsa-miR-520f-5p	HITS-CLIP	23824327
MIRT617524	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT617523	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT617522	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT486367	hsa-miR-4453	PAR-CLIP	20371350
MIRT486368	hsa-miR-4538	PAR-CLIP	20371350
MIRT486366	hsa-miR-5088-3p	PAR-CLIP	20371350
MIRT486365	hsa-miR-671-3p	PAR-CLIP	20371350
MIRT486364	hsa-miR-6070	PAR-CLIP	20371350
MIRT486363	hsa-miR-642b-5p	PAR-CLIP	20371350
MIRT486362	hsa-miR-623	PAR-CLIP	20371350
MIRT486361	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT486360	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT486359	hsa-miR-29b-2-5p	PAR-CLIP	20371350
MIRT486358	hsa-miR-3692-3p	PAR-CLIP	20371350
MIRT486357	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT486356	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT526299	hsa-miR-1306-5p	PAR-CLIP	20371350
MIRT526298	hsa-miR-4691-3p	PAR-CLIP	20371350
MIRT526297	hsa-miR-326	PAR-CLIP	20371350
MIRT526296	hsa-miR-330-5p	PAR-CLIP	20371350
MIRT526295	hsa-miR-3157-5p	PAR-CLIP	20371350
MIRT526299	hsa-miR-1306-5p	PAR-CLIP	22012620
MIRT526298	hsa-miR-4691-3p	PAR-CLIP	22012620
MIRT526297	hsa-miR-326	PAR-CLIP	22012620
MIRT526296	hsa-miR-330-5p	PAR-CLIP	22012620
MIRT526295	hsa-miR-3157-5p	PAR-CLIP	22012620
MIRT486367	hsa-miR-4453	PAR-CLIP	23592263
MIRT486368	hsa-miR-4538	PAR-CLIP	23592263
MIRT486366	hsa-miR-5088-3p	PAR-CLIP	23592263
MIRT486365	hsa-miR-671-3p	PAR-CLIP	23592263
MIRT486364	hsa-miR-6070	PAR-CLIP	23592263
MIRT486363	hsa-miR-642b-5p	PAR-CLIP	23592263
MIRT486362	hsa-miR-623	PAR-CLIP	23592263
MIRT486361	hsa-miR-204-5p	PAR-CLIP	23592263
MIRT486360	hsa-miR-211-5p	PAR-CLIP	23592263
MIRT486359	hsa-miR-29b-2-5p	PAR-CLIP	23592263
MIRT486358	hsa-miR-3692-3p	PAR-CLIP	23592263
MIRT486357	hsa-miR-4755-5p	PAR-CLIP	23592263
MIRT486356	hsa-miR-5006-3p	PAR-CLIP	23592263
MIRT452475	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT452474	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT452473	hsa-miR-4779	PAR-CLIP	23592263
MIRT452472	hsa-miR-1321	PAR-CLIP	23592263
MIRT452471	hsa-miR-4739	PAR-CLIP	23592263
MIRT452470	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT452469	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT452468	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT452467	hsa-miR-6752-3p	PAR-CLIP	23592263
MIRT452466	hsa-miR-4722-3p	PAR-CLIP	23592263
MIRT452465	hsa-miR-6727-3p	PAR-CLIP	23592263
MIRT452464	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452463	hsa-miR-4510	PAR-CLIP	23592263
MIRT452462	hsa-miR-6127	PAR-CLIP	23592263
MIRT452461	hsa-miR-6129	PAR-CLIP	23592263
MIRT452460	hsa-miR-6130	PAR-CLIP	23592263
MIRT452459	hsa-miR-6133	PAR-CLIP	23592263
MIRT452458	hsa-miR-765	PAR-CLIP	23592263
MIRT452457	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT452456	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT452455	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT452454	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT452453	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT452452	hsa-miR-5698	PAR-CLIP	23592263
MIRT452451	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT452449	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT452450	hsa-miR-548l	PAR-CLIP	23592263
MIRT452448	hsa-miR-3173-3p	PAR-CLIP	23592263
MIRT452447	hsa-miR-6891-5p	PAR-CLIP	23592263
MIRT452446	hsa-miR-141-5p	PAR-CLIP	23592263
MIRT452445	hsa-miR-205-3p	PAR-CLIP	23592263
MIRT452444	hsa-miR-873-5p	PAR-CLIP	23592263
MIRT452443	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT449176	hsa-miR-106a-5p	PAR-CLIP	22100165
MIRT449175	hsa-miR-106b-5p	PAR-CLIP	22100165
MIRT449174	hsa-miR-17-5p	PAR-CLIP	22100165
MIRT449173	hsa-miR-20a-5p	PAR-CLIP	22100165
MIRT449172	hsa-miR-20b-5p	PAR-CLIP	22100165
MIRT449171	hsa-miR-519d-3p	PAR-CLIP	22100165
MIRT449170	hsa-miR-526b-3p	PAR-CLIP	22100165
MIRT449169	hsa-miR-93-5p	PAR-CLIP	22100165
MIRT449168	hsa-miR-302a-3p	PAR-CLIP	22100165
MIRT449167	hsa-miR-302b-3p	PAR-CLIP	22100165
MIRT449157	hsa-miR-302c-3p	PAR-CLIP	22100165
MIRT449166	hsa-miR-302d-3p	PAR-CLIP	22100165
MIRT449165	hsa-miR-302e	PAR-CLIP	22100165
MIRT449164	hsa-miR-372-3p	PAR-CLIP	22100165
MIRT449163	hsa-miR-373-3p	PAR-CLIP	22100165
MIRT449162	hsa-miR-520a-3p	PAR-CLIP	22100165
MIRT449161	hsa-miR-520b	PAR-CLIP	22100165
MIRT449160	hsa-miR-520c-3p	PAR-CLIP	22100165
MIRT449159	hsa-miR-520d-3p	PAR-CLIP	22100165
MIRT449158	hsa-miR-520e	PAR-CLIP	22100165
MIRT449157	hsa-miR-302c-3p	PAR-CLIP	22100165
MIRT449156	hsa-miR-520f-3p	PAR-CLIP	22100165
MIRT449155	hsa-miR-636	PAR-CLIP	22100165
MIRT449154	hsa-miR-1273e	PAR-CLIP	22100165
MIRT449153	hsa-miR-6818-5p	PAR-CLIP	22100165
MIRT1379558	hsa-miR-1226	CLIP-seq
MIRT1379559	hsa-miR-1234	CLIP-seq
MIRT1379560	hsa-miR-1286	CLIP-seq
MIRT1379561	hsa-miR-2116	CLIP-seq
MIRT1379562	hsa-miR-214	CLIP-seq
MIRT1379563	hsa-miR-2861	CLIP-seq
MIRT1379564	hsa-miR-3127-3p	CLIP-seq
MIRT1379565	hsa-miR-338-3p	CLIP-seq
MIRT1379566	hsa-miR-342-5p	CLIP-seq
MIRT1379567	hsa-miR-3619-5p	CLIP-seq
MIRT1379568	hsa-miR-3679-3p	CLIP-seq
MIRT1379569	hsa-miR-3937	CLIP-seq
MIRT1379570	hsa-miR-4279	CLIP-seq
MIRT1379571	hsa-miR-4292	CLIP-seq
MIRT1379572	hsa-miR-4308	CLIP-seq
MIRT1379573	hsa-miR-4327	CLIP-seq
MIRT1379574	hsa-miR-4328	CLIP-seq
MIRT1379575	hsa-miR-4435	CLIP-seq
MIRT1379576	hsa-miR-4436a	CLIP-seq
MIRT1379577	hsa-miR-4530	CLIP-seq
MIRT1379578	hsa-miR-4651	CLIP-seq
MIRT1379579	hsa-miR-4664-5p	CLIP-seq
MIRT1379580	hsa-miR-4677-5p	CLIP-seq
MIRT1379581	hsa-miR-4685-5p	CLIP-seq
MIRT1379582	hsa-miR-4733-3p	CLIP-seq
MIRT1379583	hsa-miR-550a	CLIP-seq
MIRT1379584	hsa-miR-608	CLIP-seq
MIRT1379585	hsa-miR-760	CLIP-seq
MIRT1379586	hsa-miR-761	CLIP-seq
MIRT2113379	hsa-miR-1280	CLIP-seq
MIRT2113380	hsa-miR-1298	CLIP-seq
MIRT2113381	hsa-miR-3130-3p	CLIP-seq
MIRT2113382	hsa-miR-3911	CLIP-seq
MIRT2113383	hsa-miR-3934	CLIP-seq
MIRT2113384	hsa-miR-4270	CLIP-seq
MIRT2113385	hsa-miR-4286	CLIP-seq
MIRT2113386	hsa-miR-4441	CLIP-seq
MIRT2113387	hsa-miR-4665-3p	CLIP-seq
MIRT2113388	hsa-miR-4667-5p	CLIP-seq
MIRT2113389	hsa-miR-4700-5p	CLIP-seq
MIRT2113390	hsa-miR-4757-5p	CLIP-seq
MIRT2113391	hsa-miR-4793-3p	CLIP-seq
MIRT2113392	hsa-miR-552	CLIP-seq
MIRT2113393	hsa-miR-616	CLIP-seq
MIRT2113394	hsa-miR-637	CLIP-seq
MIRT2336420	hsa-miR-146b-3p	CLIP-seq
MIRT2336421	hsa-miR-185	CLIP-seq
MIRT2336422	hsa-miR-1909	CLIP-seq
MIRT2336423	hsa-miR-1913	CLIP-seq
MIRT2336424	hsa-miR-3150a-3p	CLIP-seq
MIRT2336425	hsa-miR-3173-5p	CLIP-seq
MIRT2336426	hsa-miR-3175	CLIP-seq
MIRT2336427	hsa-miR-324-3p	CLIP-seq
MIRT2336428	hsa-miR-346	CLIP-seq
MIRT1379571	hsa-miR-4292	CLIP-seq
MIRT2336429	hsa-miR-4306	CLIP-seq
MIRT2336430	hsa-miR-4644	CLIP-seq
MIRT2113388	hsa-miR-4667-5p	CLIP-seq
MIRT2113389	hsa-miR-4700-5p	CLIP-seq
MIRT2336431	hsa-miR-4736	CLIP-seq
MIRT2336432	hsa-miR-491-5p	CLIP-seq
MIRT2336433	hsa-miR-589	CLIP-seq
MIRT2336434	hsa-miR-874	CLIP-seq
MIRT2336435	hsa-miR-939	CLIP-seq
MIRT2113392	hsa-miR-552	CLIP-seq
MIRT2460246	hsa-miR-122	CLIP-seq
MIRT2460247	hsa-miR-3123	CLIP-seq
MIRT2460248	hsa-miR-3545-5p	CLIP-seq
MIRT2460249	hsa-miR-4694-3p	CLIP-seq
MIRT2460250	hsa-miR-522	CLIP-seq
MIRT2630237	hsa-miR-1207-5p	CLIP-seq
MIRT2630238	hsa-miR-1254	CLIP-seq
MIRT2630239	hsa-miR-1293	CLIP-seq
MIRT2336422	hsa-miR-1909	CLIP-seq
MIRT1379563	hsa-miR-2861	CLIP-seq
MIRT2630240	hsa-miR-3116	CLIP-seq
MIRT2630241	hsa-miR-3616-3p	CLIP-seq
MIRT2630242	hsa-miR-4254	CLIP-seq
MIRT2630243	hsa-miR-4436b-3p	CLIP-seq
MIRT2630244	hsa-miR-4483	CLIP-seq
MIRT1379581	hsa-miR-4685-5p	CLIP-seq
MIRT2630245	hsa-miR-4763-3p	CLIP-seq
MIRT1379585	hsa-miR-760	CLIP-seq
MIRT2630237	hsa-miR-1207-5p	CLIP-seq
MIRT2630238	hsa-miR-1254	CLIP-seq
MIRT2630239	hsa-miR-1293	CLIP-seq
MIRT2336422	hsa-miR-1909	CLIP-seq
MIRT1379563	hsa-miR-2861	CLIP-seq
MIRT2630240	hsa-miR-3116	CLIP-seq
MIRT2630241	hsa-miR-3616-3p	CLIP-seq
MIRT2630242	hsa-miR-4254	CLIP-seq
MIRT2630243	hsa-miR-4436b-3p	CLIP-seq
MIRT2630244	hsa-miR-4483	CLIP-seq
MIRT2630245	hsa-miR-4763-3p	CLIP-seq

Show/Hide all (24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IEA
GO:0005768	Component	Endosome	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0006886	Process	Intracellular protein transport	IEA
GO:0007218	Process	Neuropeptide signaling pathway	NAS	11499680
GO:0008188	Function	Neuropeptide receptor activity	NAS	11499680
GO:0014069	Component	Postsynaptic density	IEA
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	NAS	11499680
GO:0030425	Component	Dendrite	IEA
GO:0030659	Component	Cytoplasmic vesicle membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031901	Component	Early endosome membrane	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0043197	Component	Dendritic spine	IEA
GO:0043204	Component	Perikaryon	IEA
GO:0045202	Component	Synapse	IEA
GO:0045211	Component	Postsynaptic membrane	IEA
GO:0055038	Component	Recycling endosome membrane	IEA
GO:0060292	Process	Long-term synaptic depression	IEA
GO:0098839	Component	Postsynaptic density membrane	IEA

MIM	HGNC	e!Ensembl
606284	16698	ENSG00000184985

Q96PQ0

Protein name

VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain]

Protein function

The heterodimer formed by NGFR and SORCS2 functions as receptor for the precursor forms of NGF (proNGF) and BDNF (proBDNF) (PubMed:22155786, PubMed:24908487). ProNGF and proBDNF binding both promote axon growth cone collapse (in vitro) (PubMed:2

PDB

1WGO

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15902	Sortilin-Vps10	179 → 611	Sortilin, neurotensin receptor 3,	Domain
PF15901	Sortilin_C	613 → 775	Sortilin, neurotensin receptor 3, C-terminal	Domain
PF00801	PKD	788 → 863	PKD domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected on neurons in the caudate region (PubMed:28469074). Detected on neurons in the hippocampus (at protein level) (PubMed:30840898). Highly expressed in brain and kidney. Detected at low levels in heart, liver, small intestine, sk

Sequence

MAHRGPSRASKGPGPTARAPSPGAPPPPRSPRSRPLLLLLLLLGACGAAGRSPEPGRLGP
HAQLTRVPRSPPAGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRRWERA
APLAGVASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESS
LWRSSDFGTSYTKLTLQPGVTTVIDNFYICPTNKRKVILVSSSLSDRDQSLFLSADEGAT
FQKQPIPFFVETLIFHPKEEDKVLAYTKESKLYVSSDLGKKWTLLQERVTKDHVFWSVSG
VDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGSLTVQDDYIFFKATS
ANQTKYYVSYRRNEFVLMKLPKYALPKDLQIISTDESQVFVAVQEWYQMDTYNLYQSDPR
GVRYALVLQDVRSSRQAEESVLIDILEVRGVKGVFLANQKIDGKVMTLITYNKGRDWDYL
RPPSMDMNGKPTNCKPPDCHLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLGSQLVEY
KEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDEGLTWSTHN
FTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFSRQCGEEDYSSWELS
NLQGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRVCECRDSDFLCDYGFERSSSSES
STNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGGVDMQQSQVQLQCPLTPP
RGLQVSIQGEAVAVRPGEDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRH
RYESPGIYRVSVRAENTAGHDEAVLFVQVNSPLQALYLEVVPVIGLNQEVNLTAVLLPLN
PNLTVFYWWIGHSLQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSVLQDSRVLRVLDQFQ
VMPLQFSKELDAYNPNTPEWREDVGLVVTRLLSKETSVPQELLVTVVKPGLPTLADLYVL
LPPPRPTRKRSLSSDKRLAAIQQVLNAQKISFLLRGGVRVLVALRDTGTGAEQLGGGGGY
WAVVVLFVIGLFAAGAFILYKFKRKRPGRTVYAQMHNEKEQEMTSPVSHSEDVQGAVQGN
HSGVVLSINSREMHSYLVS

Sequence length

1159

Interactions

View interactions

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Cervical cancer	Benign	rs150440148	RCV005908478
Clear cell carcinoma of kidney	Benign	rs150440148	RCV005908479
Malignant tumor of esophagus	Uncertain significance	rs368388764	RCV005927226
Uterine corpus endometrial carcinoma	Benign	rs150440148	RCV005908480

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Alcohol Withdrawal Seizures	Associate	30252935
Alzheimer Disease	Associate	23673467
Anxiety	Associate	35743044
Carcinoma Non Small Cell Lung	Associate	21483023
Colorectal Neoplasms	Associate	27609023
Death	Associate	21483023
Diabetes Mellitus	Associate	28068899
Fetal Diseases	Associate	36585686
Neoplasms	Associate	38111983
Obesity	Associate	28068899
Substance Withdrawal Syndrome	Associate	30252935

SORCS2 (sortilin related VPS10 domain containing receptor 2)