KIAA1328 (KIAA1328)

Gene

• Entrez ID: 57536
• Gene name: KIAA1328
• Gene symbol: KIAA1328
• Synonyms (NCBI Gene): -
• Chromosome: 18
• Chromosome location: 18q12.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017652	hsa-miR-335-5p	Microarray	18185580
MIRT702496	hsa-miR-6888-5p	HITS-CLIP	23313552
MIRT702495	hsa-miR-3929	HITS-CLIP	23313552
MIRT702494	hsa-miR-4419b	HITS-CLIP	23313552
MIRT702493	hsa-miR-4478	HITS-CLIP	23313552
MIRT702492	hsa-miR-5690	HITS-CLIP	23313552
MIRT702491	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687749	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT702490	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT702489	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT702488	hsa-let-7a-5p	HITS-CLIP	23313552
MIRT702487	hsa-let-7b-5p	HITS-CLIP	23313552
MIRT702486	hsa-let-7c-5p	HITS-CLIP	23313552
MIRT702485	hsa-let-7d-5p	HITS-CLIP	23313552
MIRT702484	hsa-let-7e-5p	HITS-CLIP	23313552
MIRT702483	hsa-let-7f-5p	HITS-CLIP	23313552
MIRT702482	hsa-let-7g-5p	HITS-CLIP	23313552
MIRT702481	hsa-let-7i-5p	HITS-CLIP	23313552
MIRT702480	hsa-miR-4458	HITS-CLIP	23313552
MIRT702479	hsa-miR-4500	HITS-CLIP	23313552
MIRT702478	hsa-miR-98-5p	HITS-CLIP	23313552
MIRT702477	hsa-miR-202-3p	HITS-CLIP	23313552
MIRT702476	hsa-miR-214-5p	HITS-CLIP	23313552
MIRT702475	hsa-miR-6811-3p	HITS-CLIP	23313552
MIRT702474	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT702473	hsa-miR-6769a-5p	HITS-CLIP	23313552
MIRT702472	hsa-miR-6769b-5p	HITS-CLIP	23313552
MIRT702471	hsa-miR-1271-3p	HITS-CLIP	23313552
MIRT702470	hsa-miR-550a-3-5p	HITS-CLIP	23313552
MIRT702469	hsa-miR-550a-5p	HITS-CLIP	23313552
MIRT702468	hsa-miR-6748-5p	HITS-CLIP	23313552
MIRT702467	hsa-miR-7977	HITS-CLIP	23313552
MIRT702466	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT702465	hsa-miR-6514-3p	HITS-CLIP	23313552
MIRT702464	hsa-miR-6741-5p	HITS-CLIP	23313552
MIRT702463	hsa-miR-665	HITS-CLIP	23313552
MIRT687765	hsa-miR-3714	HITS-CLIP	23313552
MIRT687764	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT687763	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT687762	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687761	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687760	hsa-miR-940	HITS-CLIP	23313552
MIRT687759	hsa-miR-3622a-3p	HITS-CLIP	23313552
MIRT687758	hsa-miR-3622b-3p	HITS-CLIP	23313552
MIRT687757	hsa-miR-6765-3p	HITS-CLIP	23313552
MIRT687756	hsa-miR-1288-5p	HITS-CLIP	23313552
MIRT687755	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT687754	hsa-miR-4459	HITS-CLIP	23313552
MIRT687753	hsa-miR-4433a-3p	HITS-CLIP	23313552
MIRT687752	hsa-miR-4514	HITS-CLIP	23313552
MIRT687751	hsa-miR-4692	HITS-CLIP	23313552
MIRT687750	hsa-miR-544b	HITS-CLIP	23313552
MIRT687749	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT687748	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT687747	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT687746	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT687745	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT687744	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT687743	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT687742	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT687741	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT687740	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT687739	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT687738	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT687737	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT687736	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT687735	hsa-miR-3689c	HITS-CLIP	23313552
MIRT687734	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT687733	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT687732	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT687731	hsa-miR-3122	HITS-CLIP	23313552
MIRT687730	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT687729	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT687728	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT702496	hsa-miR-6888-5p	HITS-CLIP	23313552
MIRT702495	hsa-miR-3929	HITS-CLIP	23313552
MIRT702494	hsa-miR-4419b	HITS-CLIP	23313552
MIRT702493	hsa-miR-4478	HITS-CLIP	23313552
MIRT702492	hsa-miR-5690	HITS-CLIP	23313552
MIRT702491	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT687749	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT702490	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT702489	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT702488	hsa-let-7a-5p	HITS-CLIP	23313552
MIRT702487	hsa-let-7b-5p	HITS-CLIP	23313552
MIRT702486	hsa-let-7c-5p	HITS-CLIP	23313552
MIRT702485	hsa-let-7d-5p	HITS-CLIP	23313552
MIRT702484	hsa-let-7e-5p	HITS-CLIP	23313552
MIRT702483	hsa-let-7f-5p	HITS-CLIP	23313552
MIRT702482	hsa-let-7g-5p	HITS-CLIP	23313552
MIRT702481	hsa-let-7i-5p	HITS-CLIP	23313552
MIRT702480	hsa-miR-4458	HITS-CLIP	23313552
MIRT702479	hsa-miR-4500	HITS-CLIP	23313552
MIRT702478	hsa-miR-98-5p	HITS-CLIP	23313552
MIRT702477	hsa-miR-202-3p	HITS-CLIP	23313552
MIRT702476	hsa-miR-214-5p	HITS-CLIP	23313552
MIRT702475	hsa-miR-6811-3p	HITS-CLIP	23313552
MIRT702474	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT702473	hsa-miR-6769a-5p	HITS-CLIP	23313552
MIRT702472	hsa-miR-6769b-5p	HITS-CLIP	23313552
MIRT702471	hsa-miR-1271-3p	HITS-CLIP	23313552
MIRT702470	hsa-miR-550a-3-5p	HITS-CLIP	23313552
MIRT702469	hsa-miR-550a-5p	HITS-CLIP	23313552
MIRT702468	hsa-miR-6748-5p	HITS-CLIP	23313552
MIRT702467	hsa-miR-7977	HITS-CLIP	23313552
MIRT702466	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT702465	hsa-miR-6514-3p	HITS-CLIP	23313552
MIRT702464	hsa-miR-6741-5p	HITS-CLIP	23313552
MIRT702463	hsa-miR-665	HITS-CLIP	23313552
MIRT687765	hsa-miR-3714	HITS-CLIP	23313552
MIRT687764	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT687763	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT687762	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT687761	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT687760	hsa-miR-940	HITS-CLIP	23313552
MIRT687759	hsa-miR-3622a-3p	HITS-CLIP	23313552
MIRT687758	hsa-miR-3622b-3p	HITS-CLIP	23313552
MIRT687757	hsa-miR-6765-3p	HITS-CLIP	23313552
MIRT687756	hsa-miR-1288-5p	HITS-CLIP	23313552
MIRT687755	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT687754	hsa-miR-4459	HITS-CLIP	23313552
MIRT687753	hsa-miR-4433a-3p	HITS-CLIP	23313552
MIRT687752	hsa-miR-4514	HITS-CLIP	23313552
MIRT687751	hsa-miR-4692	HITS-CLIP	23313552
MIRT687750	hsa-miR-544b	HITS-CLIP	23313552
MIRT687749	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT687748	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT687747	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT687746	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT687745	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT687744	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT687743	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT687742	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT687741	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT687740	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT687739	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT687738	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT687737	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT687736	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT687735	hsa-miR-3689c	HITS-CLIP	23313552
MIRT687734	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT687733	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT687732	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT687731	hsa-miR-3122	HITS-CLIP	23313552
MIRT687730	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT687729	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT687728	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT1090021	hsa-miR-149	CLIP-seq
MIRT1090022	hsa-miR-2052	CLIP-seq
MIRT1090023	hsa-miR-3064-5p	CLIP-seq
MIRT1090024	hsa-miR-3065-5p	CLIP-seq
MIRT1090025	hsa-miR-3545-3p	CLIP-seq
MIRT1090026	hsa-miR-3591-3p	CLIP-seq
MIRT1090027	hsa-miR-4680-5p	CLIP-seq
MIRT1090028	hsa-miR-4698	CLIP-seq
MIRT1090029	hsa-miR-4771	CLIP-seq
MIRT1090030	hsa-miR-4794	CLIP-seq
MIRT1090031	hsa-miR-639	CLIP-seq
MIRT1090032	hsa-miR-720	CLIP-seq
MIRT1090033	hsa-miR-767-5p	CLIP-seq
MIRT1090034	hsa-miR-938	CLIP-seq
MIRT2024024	hsa-miR-1323	CLIP-seq
MIRT1090024	hsa-miR-3065-5p	CLIP-seq
MIRT2024025	hsa-miR-30a	CLIP-seq
MIRT2024026	hsa-miR-30b	CLIP-seq
MIRT2024027	hsa-miR-30c	CLIP-seq
MIRT2024028	hsa-miR-30d	CLIP-seq
MIRT2024029	hsa-miR-30e	CLIP-seq
MIRT2024030	hsa-miR-3160-5p	CLIP-seq
MIRT2024031	hsa-miR-326	CLIP-seq
MIRT2024032	hsa-miR-330-5p	CLIP-seq
MIRT2024033	hsa-miR-3657	CLIP-seq
MIRT2024034	hsa-miR-4468	CLIP-seq
MIRT2024035	hsa-miR-4669	CLIP-seq
MIRT2024036	hsa-miR-4768-5p	CLIP-seq
MIRT2024037	hsa-miR-548ad	CLIP-seq
MIRT2024038	hsa-miR-548o	CLIP-seq
MIRT2024039	hsa-miR-587	CLIP-seq
MIRT2255053	hsa-miR-1207-5p	CLIP-seq
MIRT2255054	hsa-miR-1297	CLIP-seq
MIRT2024024	hsa-miR-1323	CLIP-seq
MIRT2255055	hsa-miR-1909	CLIP-seq
MIRT2255056	hsa-miR-26a	CLIP-seq
MIRT2255057	hsa-miR-26b	CLIP-seq
MIRT2255058	hsa-miR-4465	CLIP-seq
MIRT2255059	hsa-miR-4477b	CLIP-seq
MIRT2255060	hsa-miR-4688	CLIP-seq
MIRT2255061	hsa-miR-4711-5p	CLIP-seq
MIRT2255062	hsa-miR-4736	CLIP-seq
MIRT2255063	hsa-miR-4763-3p	CLIP-seq
MIRT2255064	hsa-miR-539	CLIP-seq
MIRT2024037	hsa-miR-548ad	CLIP-seq
MIRT2024038	hsa-miR-548o	CLIP-seq
MIRT2438214	hsa-miR-346	CLIP-seq
MIRT2438215	hsa-miR-4712-3p	CLIP-seq
MIRT2438216	hsa-miR-4738-3p	CLIP-seq
MIRT2438217	hsa-miR-4762-3p	CLIP-seq
MIRT2438218	hsa-miR-4766-5p	CLIP-seq
MIRT2557168	hsa-miR-1294	CLIP-seq
MIRT2438214	hsa-miR-346	CLIP-seq
MIRT2557169	hsa-miR-4316	CLIP-seq
MIRT2557170	hsa-miR-4501	CLIP-seq
MIRT2557171	hsa-miR-4668-3p	CLIP-seq
MIRT2438215	hsa-miR-4712-3p	CLIP-seq
MIRT2438216	hsa-miR-4738-3p	CLIP-seq
MIRT2438217	hsa-miR-4762-3p	CLIP-seq
MIRT2438218	hsa-miR-4766-5p	CLIP-seq
MIRT2557168	hsa-miR-1294	CLIP-seq
MIRT2438214	hsa-miR-346	CLIP-seq
MIRT2557169	hsa-miR-4316	CLIP-seq
MIRT2557170	hsa-miR-4501	CLIP-seq
MIRT2557171	hsa-miR-4668-3p	CLIP-seq
MIRT2438215	hsa-miR-4712-3p	CLIP-seq
MIRT2438216	hsa-miR-4738-3p	CLIP-seq
MIRT2438217	hsa-miR-4762-3p	CLIP-seq
MIRT2438218	hsa-miR-4766-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	15656913, 32296183

Other IDs

• MIM: 616480
• HGNC: 29248
• e!Ensembl: ENSG00000150477

Protein

• UniProt ID: Q86T90
• Protein name: Protein hinderin
• Protein function: Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15369	KIAA1328	93 → 410	Uncharacterised protein KIAA1328	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:15656913}.
• Sequence:

  MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
  DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
  ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
  SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
  AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
  TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
  QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW
  LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD
  ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN
  HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI

• Sequence length: 577

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial cancer of breast	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
KIAA1328-related disorder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOPATHY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NECROTIZING ENTEROCOLITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SUBSTANCE ABUSE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations