Gene Gene information from NCBI Gene database.
Entrez ID 57532
Gene name Nuclear FMR1 interacting protein 2
Gene symbol NUFIP2
Synonyms (NCBI Gene)
182-FIP82-FIPFIP-82NUFP2PIG1
Chromosome 17
Chromosome location 17q11.2
miRNA miRNA information provided by mirtarbase database.
3245
miRTarBase ID miRNA Experiments Reference
MIRT005142 hsa-miR-30a-5p pSILAC 18668040
MIRT016195 hsa-miR-590-3p Sequencing 20371350
MIRT019613 hsa-miR-340-5p Sequencing 20371350
MIRT021149 hsa-miR-186-5p Sequencing 20371350
MIRT021672 hsa-miR-140-3p Sequencing 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IBA
GO:0003723 Function RNA binding IDA 12837692
GO:0003723 Function RNA binding IEA
GO:0005515 Function Protein binding IPI 12837692, 16407062, 21653829, 25416956, 26184334, 28514442, 32296183, 32525608, 32814053, 33961781, 35709258
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609356 17634 ENSG00000108256
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z417
Protein name FMR1-interacting protein NUFIP2 (82 kDa FMRP-interacting protein) (82-FIP) (Cell proliferation-inducing gene 1 protein) (FMRP-interacting protein 2) (Nuclear FMR1-interacting protein 2)
Protein function Binds RNA.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15293 NUFIP2 89 688 Nuclear fragile X mental retardation-interacting protein 2 Family
Sequence
Sequence length 695
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
9
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ATTENTION DEFICIT HYPERACTIVITY DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
GOUT GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
MIGRAINE DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Abnormalities Drug Induced Associate 20439717
★☆☆☆☆
Found in Text Mining only
Alzheimer Disease Associate 37440991
★☆☆☆☆
Found in Text Mining only
Arthritis Rheumatoid Associate 33482886
★☆☆☆☆
Found in Text Mining only
Attention Deficit Disorder with Hyperactivity Associate 32460900
★☆☆☆☆
Found in Text Mining only
Autism Spectrum Disorder Associate 24267887, 27260404, 28344757, 32243819
★☆☆☆☆
Found in Text Mining only
Autistic Disorder Associate 27260404, 30664714, 36070702
★☆☆☆☆
Found in Text Mining only
Down Syndrome Associate 36070702
★☆☆☆☆
Found in Text Mining only
Fragile X Syndrome Inhibit 15649335
★☆☆☆☆
Found in Text Mining only
Fragile X Syndrome Associate 16407062, 23912948, 32460900, 32525608, 34312401, 36070702
★☆☆☆☆
Found in Text Mining only
Intellectual Disability Associate 33149277
★☆☆☆☆
Found in Text Mining only