XPO5 (exportin 5)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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57510 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Exportin 5 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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XPO5 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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exp5 |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p21.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9HAV4 | ||||||||||
| Protein name | Exportin-5 (Exp5) (Ran-binding protein 21) | ||||||||||
| Protein function | Mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos). XPO5 in the nucleus binds cooperatively to the RNA and to the GTPase Ran in its active GTP-bound form. Proteins conta | ||||||||||
| PDB | 3A6P , 5YU6 , 5YU7 | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in heart, brain, placenta, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:11777942}. | ||||||||||
| Sequence |
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| Sequence length | 1204 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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