Gene Gene information from NCBI Gene database.
Entrez ID 57464
Gene name Striatin interacting protein 2
Gene symbol STRIP2
Synonyms (NCBI Gene)
FAM40BFAR11B
Chromosome 7
Chromosome location 7q32.1
miRNA miRNA information provided by mirtarbase database.
750
miRTarBase ID miRNA Experiments Reference
MIRT038167 hsa-miR-423-5p CLASH 23622248
MIRT621983 hsa-miR-6736-3p HITS-CLIP 23824327
MIRT621982 hsa-miR-212-5p HITS-CLIP 23824327
MIRT621981 hsa-miR-3189-3p HITS-CLIP 23824327
MIRT621980 hsa-miR-214-5p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IDA 21834987
GO:0005737 Component Cytoplasm IEA
GO:0005829 Component Cytosol IBA
GO:0005829 Component Cytosol IDA
GO:0007010 Process Cytoskeleton organization IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
617919 22209 ENSG00000128578
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9ULQ0
Protein name Striatin-interacting protein 2 (Protein FAM40B)
Protein function Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (PubMed:21834987). Calmodulin-binding scaffolding protein which is the center of the striatin-interacting phosphatase and kina
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07923 N1221 49 324 N1221-like protein Family
PF11882 DUF3402 486 632 Domain of unknown function (DUF3402) Family
PF11882 DUF3402 622 792 Domain of unknown function (DUF3402) Family
Sequence
MEDPAAPGTGGPPANGNGNGGGKGKQAAPKGREAFRSQRRESEGSVDCPTLEFEYGDADG
HAAELSELYSYTENLEFTNNRRCFEEDFKTQVQGKEWLELEEDAQKAYIMGLLDRLEVVS
RERRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSTFLELLHMEIDNSQ
ACSSALRKPAVSIADSTELRVLLSVMYLMVENIRLERETDPCGWRTARETFRTELSFSMH
NEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQTLKVQKRAELGL
PPLAEDSIQVVKSMRAASPPSYTL
DLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNE
RDLFKTEEPATEEEEESAGDGERTLDGELDLLEQDPLVPPPPSQAPLSAERVAFPKGLPW
APKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIK
NEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINI
LADVLPEEMPITVLQSMKLGIDVNRHKEIIVKSISTLLLLLLKHFKLNHIYQFEYVSQHL
VFANCIPLILKFFNQNILSYI
TAKNSISVLDYPCCTIQDLPELTTESLEAGDNSQFCWRN
LFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKLQTKYL
GRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYD
RPQDSEFSPVDN
CLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH
Sequence length 834
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
GILLES DE LA TOURETTE SYNDROME Disgenet
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Adenocarcinoma of Lung Associate 31901223
★☆☆☆☆
Found in Text Mining only
Carcinoma Non Small Cell Lung Associate 36639675
★☆☆☆☆
Found in Text Mining only
Neoplasm Metastasis Inhibit 36639675
★☆☆☆☆
Found in Text Mining only
Neoplasms Associate 31901223
★☆☆☆☆
Found in Text Mining only
Neoplasms Stimulate 36639675
★☆☆☆☆
Found in Text Mining only