Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
574508
Gene name Gene Name - the full gene name approved by the HGNC.
MicroRNA 505
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIR505
Synonyms (NCBI Gene) Gene synonyms aliases
MIRN505, hsa-mir-505, mir-505
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xq27.1
Summary Summary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005615 Component Extracellular space HDA 26646931
GO:0005615 Component Extracellular space IDA 25203061, 25449503
GO:0016442 Component RISC complex IEA
GO:0016525 Process Negative regulation of angiogenesis IDA 25449503
GO:0035195 Process MiRNA-mediated post-transcriptional gene silencing IDA 25449503
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
301053 32140 ENSG00000207633
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Prostate cancer Prostate cancer miRNA (miR)?205, miR?221, miR?222, miR?30c, miR?224, miR?455?3p, miR?23b and miR?505 were downregulated in patients with prostate cancer (PCa) and were experimentally validated to function as tumor suppressors in prostate cancer cells, affecting tumor pro 32901864 CBGDA
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma Associate 25091571
Alzheimer Disease Associate 25992776
Aortic Valve Stenosis Associate 27579316
Atypical Squamous Cells of the Cervix Associate 39526479
Breast Neoplasms Associate 23144930
Carcinogenesis Associate 29251324
Carcinogenesis Inhibit 31322225
Carcinoma Hepatocellular Inhibit 31160483
Carcinoma Squamous Cell Associate 39526479
Cholangiocarcinoma Associate 33301605