MIR503 (microRNA 503)

Gene

• Entrez ID: 574506
• Gene name: MicroRNA 503
• Gene symbol: MIR503
• Synonyms (NCBI Gene): MIRN503, hsa-mir-503, mir-503
• Chromosome: X
• Chromosome location: Xq26.3
• Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001937	Process	Negative regulation of endothelial cell proliferation	IDA	21220732
GO:0010596	Process	Negative regulation of endothelial cell migration	IDA	21220732
GO:0010812	Process	Negative regulation of cell-substrate adhesion	IDA	21220732
GO:0016442	Component	RISC complex	IEA
GO:0016525	Process	Negative regulation of angiogenesis	IGI
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IDA	21220732, 23263626, 23724129, 26268439
GO:0035195	Process	MiRNA-mediated post-transcriptional gene silencing	IEA
GO:0035278	Process	MiRNA-mediated gene silencing by inhibition of translation	IDA	21220732
GO:0040037	Process	Negative regulation of fibroblast growth factor receptor signaling pathway	IGI	23263626
GO:0043537	Process	Negative regulation of blood vessel endothelial cell migration	IGI	23263626
GO:0070317	Process	Negative regulation of G0 to G1 transition	IGI	23263626
GO:0070373	Process	Negative regulation of ERK1 and ERK2 cascade	IGI	23263626
GO:0072563	Component	Endothelial microparticle	IDA	26268439
GO:0090051	Process	Negative regulation of cell migration involved in sprouting angiogenesis	IGI
GO:1902807	Process	Negative regulation of cell cycle G1/S phase transition	IDA	21220732
GO:1903231	Function	MRNA base-pairing post-transcriptional repressor activity	IDA	21220732, 23263626, 23724129, 26268439
GO:1903588	Process	Negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA	21220732
GO:1903589	Process	Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IGI	26268439
GO:1904706	Process	Negative regulation of vascular associated smooth muscle cell proliferation	IDA	21220732
GO:1904706	Process	Negative regulation of vascular associated smooth muscle cell proliferation	IGI	23263626
GO:1904753	Process	Negative regulation of vascular associated smooth muscle cell migration	IDA	21220732
GO:1905563	Process	Negative regulation of vascular endothelial cell proliferation	IGI	23263626

Other IDs

• MIM: 300865
• HGNC: 32138
• e!Ensembl: ENSG00000208005

Interactions View interactions