Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
574447
Gene name Gene Name - the full gene name approved by the HGNC.
MicroRNA 146b
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MIR146B
Synonyms (NCBI Gene) Gene synonyms aliases
MIRN146B, miRNA146B, mir-146b
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q24.32
Summary Summary of gene provided in NCBI Entrez Gene.
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0016442 Component RISC complex IEA
GO:0032700 Process Negative regulation of interleukin-17 production IDA 30362152
GO:0035195 Process MiRNA-mediated post-transcriptional gene silencing IDA 30362152
GO:0035195 Process MiRNA-mediated post-transcriptional gene silencing IEA
GO:1903231 Function MRNA base-pairing post-transcriptional repressor activity IDA 30362152
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610567 32079 ENSG00000202569
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Cervical Cancer Cervical cancer Our screens identified 10 miRNAs that enhance fitness of HeLa cells and have been reported to be up-regulated in cervical cancer (Table2). 29720387 CBGDA
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Adenocarcinoma Associate 31360113
Adenocarcinoma Follicular Associate 32824921
Adenocarcinoma of Lung Associate 27081085
Adenoma Associate 36749451, 36897102
Alzheimer Disease Associate 27213057
Aortic Valve Stenosis Associate 27579316
Arthritis Rheumatoid Associate 38477951
Asthma Associate 21917308, 25217662, 29940952
Atrial Fibrillation Associate 34100730
Atypical Squamous Cells of the Cervix Associate 22136206